{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:08:09Z","timestamp":1792724889913,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2013,11,29]],"date-time":"2013-11-29T00:00:00Z","timestamp":1385683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Autism Dev Disord"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1007\/s10803-013-2009-2","type":"journal-article","created":{"date-parts":[[2013,11,28]],"date-time":"2013-11-28T12:48:43Z","timestamp":1385642923000},"page":"1425-1432","source":"Crossref","is-referenced-by-count":64,"title":["Rigid\u2013Compulsive Behaviors are Associated with Mixed Bowel Symptoms in Autism Spectrum Disorder"],"prefix":"10.1007","volume":"44","author":[{"given":"Brittany","family":"Peters","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent C.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Gorrindo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evon Batey","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pat","family":"Levitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Veenstra-VanderWeele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,11,29]]},"reference":[{"key":"2009_CR1","doi-asserted-by":"crossref","unstructured":"Adams, J., Johansen, L., Powell, L., Quig, D., & Rubin R. (2011). Gastrointestinal flora and gastrointestinal status in children with autism\u2014Comparisons to typical children and correlation with autism severity. BMC Gastrology, 11(22).","DOI":"10.1186\/1471-230X-11-22"},{"issue":"4","key":"2009_CR2","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1542\/peds.112.4.939","volume":"112","author":"N Afzal","year":"2003","unstructured":"Afzal, N., Murch, S., Thirrupathy, K., Berger, L., Fagbemi, A., & Heuschkel, R. (2003). Constipation with acquired megarectum in children with autism. Pediatrics, 112(4), 939\u2013942.","journal-title":"Pediatrics"},{"issue":"2","key":"2009_CR3","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF01537726","volume":"7","author":"H Ando","year":"1977","unstructured":"Ando, H. (1977). Training autistic children to urinate in the toilet through operant conditioning techniques. Autism and Childhood Schizophrenia, 7(2), 151\u2013163.","journal-title":"Autism and Childhood Schizophrenia"},{"key":"2009_CR4","unstructured":"Baio, J. (2012). Prevalence of autism spectrum disorders\u2014Autism and developmental disabilities monitoring network, 14 sites, United States, 2008. Surveillance Summaries, 61(SS03), 1\u201319."},{"key":"2009_CR5","volume-title":"Bayley Scales of Infant and Toddler Development: Technical Manual","author":"N Bayley","year":"2006","unstructured":"Bayley, N. (2006). Bayley Scales of Infant and Toddler Development: Technical Manual (3rd ed.). San Antonio, TX: Harcourt Assessment.","edition":"3"},{"key":"2009_CR6","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/bmj.325.7361.419","volume":"325","author":"C Black","year":"2002","unstructured":"Black, C., Kaye, J. A., & Jick, H. (2002). Relation of childhood gastrointestinal disorders to autism: Nested case-control study using data from the UK General Practice Research Database. British Medical Journal, 325, 419\u2013421.","journal-title":"British Medical Journal"},{"key":"2009_CR7","doi-asserted-by":"crossref","unstructured":"Brazzelli, M., Griffiths, P. V., Cody, J. D., & Tappin, D. (2011). Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children. Cochrane Database System Review, 12, CD002240.","DOI":"10.1002\/14651858.CD002240.pub4"},{"key":"2009_CR8","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1542\/peds.2008-0819","volume":"123","author":"DB Campbell","year":"2009","unstructured":"Campbell, D. B., Buie, T. M., Winter, H., Bauma, M., Sutcliffe, J. S., Perrin, J. M., et al. (2009). Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions. Pediatrics, 123, 1018\u20131024.","journal-title":"Pediatrics"},{"issue":"16","key":"2009_CR9","doi-asserted-by":"crossref","first-page":"6348","DOI":"10.1523\/JNEUROSCI.21-16-06348.2001","volume":"21","author":"JJ Chen","year":"2001","unstructured":"Chen, J. J., Li, Z., Pan, H., Murphy, D. L., Tami, H., Koepsell, H., et al. (2001). Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters. Journal of Neuroscience, 21(16), 6348\u20136361.","journal-title":"Journal of Neuroscience"},{"issue":"1 Suppl 1","key":"2009_CR39","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1053\/j.gastro.2003.10.012","volume":"126","author":"C Di Lorenzo","year":"2004","unstructured":"Di Lorenzo, C., & Benninga, M. A. (2004). Pathophysiology of pediatric fecal incontinence. Gastroenterology, 126(1 Suppl 1), S33\u2013S40.","journal-title":"Gastroenterology"},{"issue":"7","key":"2009_CR10","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1038\/ajg.2009.223","volume":"104","author":"AC Ford","year":"2009","unstructured":"Ford, A. C., Brandt, L. J., Young, C., Chey, W. D., Foxx-Orenstein, A. E., & Moayyedi, P. (2009). Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: Systematic review and meta-analysis. American Journal of Gastroenterology, 104(7), 1831\u20131843.","journal-title":"American Journal of Gastroenterology"},{"key":"2009_CR11","volume-title":"Diagnostic and statistical manual of mental disorders","author":"A Frances","year":"2000","unstructured":"Frances, A., Pincus, H. A., First, M. B., & Widiger, T. A. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Arlington, VA: American Psychiatric Publishing.","edition":"4"},{"issue":"2","key":"2009_CR12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ridd.2004.05.003","volume":"26","author":"RE Gabrriels","year":"2005","unstructured":"Gabrriels, R. E., Cuccaro, M. L., Hill, D. E., Ivers, B. J., & Gosldon, E. (2005). Repetitive behaviors in autism: Relationships with associated clinical features. Research in Developmental Disabilities, 26(2), 169\u2013181.","journal-title":"Research in Developmental Disabilities"},{"issue":"1","key":"2009_CR13","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/MED.0b013e32835bc703","volume":"20","author":"MD Gershon","year":"2013","unstructured":"Gershon, M. D. (2013). 5-Hydroxytryptamine (serotonin) in the gastrointestinal tract. Current opinion in Endocrinology, Diabetes, and Obesity, 20(1), 14\u201321.","journal-title":"Current opinion in Endocrinology, Diabetes, and Obesity"},{"key":"2009_CR14","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1053\/j.gastro.2005.11.057","volume":"130","author":"P Gorrindo","year":"2006","unstructured":"Gorrindo, P., Levy, R. L., Olden, K. W., Baliboff, B. D., Bradley, L. A., Francisconi, C., et al. (2006). Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology, 130, 1447\u20131458.","journal-title":"Gastroenterology"},{"issue":"2","key":"2009_CR15","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/aur.237","volume":"5","author":"P Gorrindo","year":"2012","unstructured":"Gorrindo, P., Williams, K. C., Lee, E. B., Walker, L. S., McGrew, S. G., & Levitt, P. (2012). Gastrointestinal dysfunction in autism: Parental report, clinical evaluation and associated factors. Autism Research, 5(2), 101\u2013108.","journal-title":"Autism Research"},{"key":"2009_CR16","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1053\/j.gastro.2005.11.065","volume":"130","author":"PE Hyman","year":"2006","unstructured":"Hyman, P. E., Milla, P. J., Benninga, M. A., Davidson, G. P., Fleisher, D. F., & Taminiau, J. (2006). Childhood functional gastrointestinal disorders: Neonate\/toddler. Gastroenterology, 130, 1519\u20131526.","journal-title":"Gastroenterology"},{"issue":"2","key":"2009_CR17","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1542\/peds.2008-2933","volume":"124","author":"SH Ibrahim","year":"2009","unstructured":"Ibrahim, S. H., Voigt, R. G., Katusic, S. K., Weaver, A. L., & Barbaresi, W. J. (2009). Incidence of gastrointestinal symptoms in children with autism: A population-based study. Pediatrics, 124(2), 680\u2013686.","journal-title":"Pediatrics"},{"issue":"4","key":"2009_CR18","first-page":"100","volume":"35","author":"L Kanner","year":"1968","unstructured":"Kanner, L. (1968). Autistic disturbances of affective contact. Acta Paedopsychiatrica, 35(4), 100\u2013136.","journal-title":"Acta Paedopsychiatrica"},{"issue":"1601","key":"2009_CR19","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1098\/rstb.2012.0039","volume":"367","author":"KP Lesch","year":"2012","unstructured":"Lesch, K. P., Araragi, N., Waider, J., van den Hove, D., & Gutknecht, L. (2012). Targeting brain serotonin synthesis: Insights into neurodevelopmental disorders with longterm outcomes related to negative emotionality, aggression and antisocial behavior. Philosophical Transactions of the Royal Society of London. Series B, Biological sciences, 367(1601), 2426\u20132443.","journal-title":"Philosophical Transactions of the Royal Society of London. Series B, Biological sciences"},{"issue":"7","key":"2009_CR20","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1007\/s10803-011-1379-6","volume":"42","author":"MJ Maenner","year":"2012","unstructured":"Maenner, M. J., Arneson, C. L., Levy, S. E., Kriby, R. S., Nicholas, J. S., & Durkin, M. S. (2012). Brief report: Association between behavioral features and gastrointestinal problems among children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 42(7), 1520\u20131525.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"1","key":"2009_CR21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1017\/S1092852900024123","volume":"11","author":"PS Masand","year":"2006","unstructured":"Masand, P. S., Keuthen, N. J., Gupta, S., Virk, S., Yu-Siao, B., & Kaplan, D. (2006). Prevalence of irritable bowel syndrome in obsessive\u2013compulsive disorder. CNS Spectrums, 11(1), 21\u201325.","journal-title":"CNS Spectrums"},{"key":"2009_CR22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10802-012-9668-x","volume":"41","author":"MO Mazurec","year":"2013","unstructured":"Mazurec, M. O., Vasa, R. A., Kalb, L. G., Kanne, S. M., Rosenberg, D., Keefer, A., et al. (2013). Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. Journal of Abnormal Child Psychology, 41, 165\u2013176.","journal-title":"Journal of Abnormal Child Psychology"},{"issue":"2","key":"2009_CR23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/1362361303007002004","volume":"7","author":"CA Molloy","year":"2003","unstructured":"Molloy, C. A., & Manning-Courtney, P. (2003). Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders. Autism, 7(2), 165\u2013171.","journal-title":"Autism"},{"issue":"4","key":"2009_CR24","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/00004583-200404000-00016","volume":"43","author":"EJ Mulder","year":"2004","unstructured":"Mulder, E. J., Anderson, G. M., Kema, I. P., de Bildt, A., van Lang, N. D., den Boer, J. A., et al. (2004). Platelet serotonin levels in pervasive developmental disorders and mental retardation: Diagnostic group differences, within-group distribution, and behavioral correlates. Journal of the American Academy of Child and Adolescent Psychiatry, 43(4), 491\u2013499.","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"2009_CR25","volume-title":"Mullen Scales of Early Learning","year":"1995","unstructured":"Mullen, E. (Ed.). (1995). Mullen Scales of Early Learning. Circle Pines, MN: American Guidance Service Inc."},{"issue":"5","key":"2009_CR26","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1176\/appi.ajp.163.5.934","volume":"163","author":"DG Murphy","year":"2006","unstructured":"Murphy, D. G., Daly, E., Schmitz, N., Toal, F., Murphy, K., Curran, S., et al. (2006). Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger\u2019s syndrome: An in vivo SPECT study. American Journal of Psychiatry, 163(5), 934\u2013936.","journal-title":"American Journal of Psychiatry"},{"issue":"2","key":"2009_CR27","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nrn2284","volume":"9","author":"DL Murphy","year":"2008","unstructured":"Murphy, D. L., & Lesch, K. P. (2008). Targeting the murine serotonin transporter: Insights into human neurobiology. Nature Reviews Neuroscience, 9(2), 85\u201396.","journal-title":"Nature Reviews Neuroscience"},{"key":"2009_CR28","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s10803-008-0637-8","volume":"39","author":"RN Nikolov","year":"2009","unstructured":"Nikolov, R. N., Bearss, K. E., Lettinga, J., Erickson, C., Rodowski, M., Aman, M. G., et al. (2009). Gastrointestinal symptoms in a sample of children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 39, 405\u2013413.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"2","key":"2009_CR29","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/10401239509149029","volume":"7","author":"CS North","year":"1995","unstructured":"North, C. S., Napier, M., Alpers, D. H., & Spitznagel, E. L. (1995). Complaints of constipation in obsessive\u2013compulsive disorder. Annals of Clinical Psychiatry, 7(2), 65\u201370.","journal-title":"Annals of Clinical Psychiatry"},{"key":"2009_CR30","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1053\/j.gastro.2005.08.063","volume":"130","author":"A Rasquin","year":"2006","unstructured":"Rasquin, A., Di Lorenzo, C., Forbes, D., Guiraldes, E., Hyams, J. S., Staiano, A., et al. (2006). Childhood functional gastrointestinal disorders: Child\/adolescent. Gastroenterology, 130, 1527\u20131537.","journal-title":"Gastroenterology"},{"key":"2009_CR31","volume-title":"Stanford\u2013Binet Intelligence Scales","author":"GH Roid","year":"2003","unstructured":"Roid, G. H. (2003). Stanford\u2013Binet Intelligence Scales (5th ed.). Rolling Meadows, IL: Riverside Publishing.","edition":"5"},{"key":"2009_CR32","volume-title":"Leiter International Performance Scale-Revised","author":"GH Roid","year":"1997","unstructured":"Roid, G. H., & Miller, L. J. (1997). Leiter International Performance Scale-Revised. Wood Dale, IL: Stoelting Co."},{"key":"2009_CR33","doi-asserted-by":"crossref","unstructured":"Ruepert, L., Quartero, A. O., de Wit, M. J., van der Heijden, G. J., Rubin, G., & Muris, J. W. (2011). Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome. Cochrane Database Systematic Review, 10(8).","DOI":"10.1002\/14651858.CD003460.pub3"},{"issue":"6","key":"2009_CR34","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.pediatrneurol.2008.07.019","volume":"39","author":"MD Valicenti-McDermott","year":"2008","unstructured":"Valicenti-McDermott, M. D., McVIcar, K., Cohen, H. J., Wershil, B. K., & Shinnar, S. (2008). Gastrointestinal symptoms in children with an autism spectrum disorder and language regression. Pediatric Neurology, 39(6), 392\u2013398.","journal-title":"Pediatric Neurology"},{"issue":"Suppl 2","key":"2009_CR35","doi-asserted-by":"crossref","first-page":"S128","DOI":"10.1097\/00004703-200604002-00011","volume":"27","author":"M Valicenti-McDermott","year":"2006","unstructured":"Valicenti-McDermott, M., McVicar, K., Rapin, I., Wershil, B. K., Cohen, H., & Shinnar, S. (2006). Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease. Journal of Developmental and Behavioral Pediatrics, 27(Suppl 2), S128\u2013S136.","journal-title":"Journal of Developmental and Behavioral Pediatrics"},{"issue":"1","key":"2009_CR36","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/npp.2011.185","volume":"37","author":"J Veenstra-Vanderweele","year":"2012","unstructured":"Veenstra-Vanderweele, J., & Blakely, R. D. (2012). Networking in autism: Leveraging genetic, biomarker, and model system findings in the search for new treatments. Neuropsychopharmacology, 37(1), 196\u2013212.","journal-title":"Neuropsychopharmacology"},{"key":"2009_CR37","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/DBP.0b013e31821bd06a","volume":"5","author":"LW Wang","year":"2011","unstructured":"Wang, L. W., Tancredi, D. J., & Thomas, D. W. (2011). The prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected members. Journal of Developmental and Behavioral Pediatrics, 5, 351\u2013360.","journal-title":"Journal of Developmental and Behavioral Pediatrics"},{"key":"2009_CR38","unstructured":"What is the ATN?. (2012). Autism Treatment Network. http:\/\/www.autismspeaks.org\/science\/resources-programs\/autism-treatment-network . Accessed July 12, 2012."}],"container-title":["Journal of Autism and Developmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10803-013-2009-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10803-013-2009-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10803-013-2009-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,4]],"date-time":"2019-08-04T06:15:11Z","timestamp":1564899311000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10803-013-2009-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,29]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["2009"],"URL":"https:\/\/doi.org\/10.1007\/s10803-013-2009-2","relation":{},"ISSN":["0162-3257","1573-3432"],"issn-type":[{"value":"0162-3257","type":"print"},{"value":"1573-3432","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,29]]}}}