{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T03:22:42Z","timestamp":1787714562510,"version":"build-2784847793"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Autism Dev Disord"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s10803-020-04698-8","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T05:02:30Z","timestamp":1600232550000},"page":"2068-2076","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["A Longitudinal Study of Features Associated with Autism Spectrum in Clinic Referred, Gender Diverse Adolescents Accessing Puberty Suppression Treatment"],"prefix":"10.1007","volume":"51","author":[{"given":"Ian","family":"Russell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-9471","authenticated-orcid":false,"given":"Una","family":"Masic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,16]]},"reference":[{"key":"4698_CR1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders (DSM-5\u00ae)","author":"American Psychiatric Association","year":"2013","unstructured":"American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5\u00ae). Washington, DC: American Psychiatric Pub."},{"issue":"6","key":"4698_CR2","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1192\/bjp.bp.108.059345","volume":"194","author":"S Baron-Cohen","year":"2009","unstructured":"Baron-Cohen, S., Scott, F. J., Allison, C., Williams, J., Bolton, P., Matthews, F. E., et al. (2009). Prevalence of autism-spectrum conditions: UK school-based population study. The British Journal of Psychiatry, 194(6), 500\u2013509.","journal-title":"The British Journal of Psychiatry"},{"issue":"2","key":"4698_CR3","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s00787-013-0427-5","volume":"23","author":"H Cholemkery","year":"2014","unstructured":"Cholemkery, H., Kitzerow, J., Rohrmann, S., & Freitag, C. M. (2014). Validity of the social responsiveness scale to differentiate between autism spectrum disorders and disruptive behaviour disorders. European Child & Adolescent Psychiatry, 23(2), 81\u201393.","journal-title":"European Child & Adolescent Psychiatry"},{"key":"4698_CR4","doi-asserted-by":"crossref","unstructured":"Coleman, E., Bockting, W., Botzer, M., Cohen-Kettenis, P., DeCuypere, G., Feldman, J.,... & Monstrey, S. (2012). Standards of care for the health of transsexual, transgender, and gender-nonconforming people, version 7. International Journal of Transgenderism, 13(4), 165\u2013232","DOI":"10.1080\/15532739.2011.700873"},{"key":"4698_CR5","volume-title":"Social responsiveness scale second edition (SRS-2): Manual","author":"JN Constantino","year":"2012","unstructured":"Constantino, J. N., & Gruber, C. P. (2012). Social responsiveness scale second edition (SRS-2): Manual. Torrance: Western Psychological Services."},{"issue":"11","key":"4698_CR6","doi-asserted-by":"publisher","first-page":"2206","DOI":"10.1111\/jsm.13034","volume":"12","author":"R Costa","year":"2015","unstructured":"Costa, R., Dunsford, M., Skagerberg, E., Holt, V., Carmichael, P., & Colizzi, M. (2015). Psychological support, puberty suppression, and psychosocial functioning in adolescents with gender dysphoria. The Journal of Sexual Medicine, 12(11), 2206\u20132214.","journal-title":"The Journal of Sexual Medicine"},{"issue":"4","key":"4698_CR7","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1542\/peds.2013-2958","volume":"134","author":"AL De Vries","year":"2014","unstructured":"De Vries, A. L., McGuire, J. K., Steensma, T. D., Wagenaar, E. C., Doreleijers, T. A., & Cohen-Kettenis, P. T. (2014). Young adult psychological outcome after puberty suppression and gender reassignment. Pediatrics, 134(4), 696\u2013704.","journal-title":"Pediatrics"},{"issue":"8","key":"4698_CR8","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1007\/s10803-010-0935-9","volume":"40","author":"AL De Vries","year":"2010","unstructured":"De Vries, A. L., Noens, I. L., Cohen-Kettenis, P. T., van Berckelaer-Onnes, I. A., & Doreleijers, T. A. (2010). Autism spectrum disorders in gender dysphoric children and adolescents. Journal of Autism and Developmental Disorders, 40(8), 930\u2013936.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"8","key":"4698_CR9","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1111\/j.1743-6109.2010.01943.x","volume":"8","author":"AL De Vries","year":"2011","unstructured":"De Vries, A. L., Steensma, T. D., Doreleijers, T. A., & Cohen-Kettenis, P. T. (2011). Puberty suppression in adolescents with gender identity disorder: A prospective follow-up study. The Journal of Sexual Medicine, 8(8), 2276\u20132283.","journal-title":"The Journal of Sexual Medicine"},{"issue":"6","key":"4698_CR10","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1177\/1362361316671845","volume":"21","author":"M Dean","year":"2017","unstructured":"Dean, M., Harwood, R., & Kasari, C. (2017). The art of camouflage: Gender differences in the social behaviors of girls and boys with autism spectrum disorder. Autism, 21(6), 678\u2013689.","journal-title":"Autism"},{"issue":"1","key":"4698_CR11","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1177\/1362361313500382","volume":"18","author":"TW Frazier","year":"2014","unstructured":"Frazier, T. W., Ratliff, K. R., Gruber, C., Zhang, Y., Law, P. A., & Constantino, J. N. (2014). Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the social responsiveness scale-2. Autism, 18(1), 31\u201344.","journal-title":"Autism"},{"key":"4698_CR12","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/s13229-015-0019-y","volume":"6","author":"AK Halladay","year":"2015","unstructured":"Halladay, A. K., Bishop, S., Constantino, J. N., Daniels, A. M., Koenig, K., Palmer, K., et al. (2015). Sex and gender differences in autism spectrum disorder: Summarizing evidence gaps and identifying emerging areas of priority. Molecular Autism, 6, 36. https:\/\/doi.org\/10.1186\/s13229-015-0019-y.","journal-title":"Molecular Autism"},{"issue":"1","key":"4698_CR13","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1186\/s12888-018-1800-1","volume":"18","author":"J Hayes","year":"2018","unstructured":"Hayes, J., Ford, T., Rafeeque, H., & Russell, G. (2018). Clinical practice guidelines for diagnosis of autism spectrum disorder in adults and children in the UK: A narrative review. BMC Psychiatry, 18(1), 222.","journal-title":"BMC Psychiatry"},{"issue":"4","key":"4698_CR14","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.chc.2011.08.004","volume":"20","author":"WC Hembree","year":"2011","unstructured":"Hembree, W. C. (2011). Guidelines for pubertal suspension and gender reassignment for transgender adolescents. Child and Adolescent Psychiatric Clinics, 20(4), 725\u2013732.","journal-title":"Child and Adolescent Psychiatric Clinics"},{"issue":"1","key":"4698_CR15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1177\/1362361314568899","volume":"20","author":"RM Hiller","year":"2016","unstructured":"Hiller, R. M., Young, R. L., & Weber, N. (2016). Sex differences in pre-diagnosis concerns for children later diagnosed with autism spectrum disorder. Autism, 20(1), 75\u201384.","journal-title":"Autism"},{"issue":"1","key":"4698_CR16","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1177\/1359104514558431","volume":"21","author":"V Holt","year":"2016","unstructured":"Holt, V., Skagerberg, E., & Dunsford, M. (2016). Young people with features of gender dysphoria: Demographics and associated difficulties. Clinical Child Psychology and Psychiatry, 21(1), 108\u2013118.","journal-title":"Clinical Child Psychology and Psychiatry"},{"issue":"2","key":"4698_CR17","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1111\/j.1469-7610.2012.02589.x","volume":"54","author":"V Hus","year":"2013","unstructured":"Hus, V., Bishop, S., Gotham, K., Huerta, M., & Lord, C. (2013). Factors influencing scores on the social responsiveness scale. Journal of Child Psychology and Psychiatry, 54(2), 216\u2013224.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"4698_CR18","doi-asserted-by":"publisher","first-page":"31","DOI":"10.2147\/AHMT.S135432","volume":"9","author":"R Kaltiala-Heino","year":"2018","unstructured":"Kaltiala-Heino, R., Bergman, H., Ty\u00f6l\u00e4j\u00e4rvi, M., & Fris\u00e9n, L. (2018). Gender dysphoria in adolescence: Current perspectives. Adolescent Health, Medicine and Therapeutics, 9, 31\u201341. https:\/\/doi.org\/10.2147\/AHMT.S135432.","journal-title":"Adolescent Health, Medicine and Therapeutics"},{"issue":"1","key":"4698_CR19","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13034-015-0042-y","volume":"9","author":"R Kaltiala-Heino","year":"2015","unstructured":"Kaltiala-Heino, R., Sumia, M., Ty\u00f6l\u00e4j\u00e4rvi, M., & Lindberg, N. (2015). Two years of gender identity service for minors: Overrepresentation of natal girls with severe problems in adolescent development. Child and Adolescent Psychiatry and Mental Health, 9(1), 9.","journal-title":"Child and Adolescent Psychiatry and Mental Health"},{"issue":"11","key":"4698_CR20","doi-asserted-by":"publisher","first-page":"2584","DOI":"10.1007\/s10803-013-1811-1","volume":"43","author":"M Kirkovski","year":"2013","unstructured":"Kirkovski, M., Enticott, P. G., & Fitzgerald, P. B. (2013). A review of the role of female gender in autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(11), 2584\u20132603.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"4698_CR21","doi-asserted-by":"crossref","unstructured":"Lai, M. C., Lombardo, M. V., Ruigrok, A. N., Chakrabarti, B., Auyeung, B., Szatmari, P.,... & MRC AIMS Consortium. (2017). Quantifying and exploring camouflaging in men and women with autism. Autism, 21(6), 690\u2013702","DOI":"10.1177\/1362361316671012"},{"key":"4698_CR23","unstructured":"Leef, J. H. (2018). Characteristics of autism spectrum disorder in children with gender dysphoria (Doctoral dissertation)."},{"key":"4698_CR22","doi-asserted-by":"crossref","unstructured":"Leef, J. H., Brian, J., Van der Laan, D. P., Wood, H., Scott, K., Lai, M. C.,... & Zucker, K. J. (2019). Traits of autism spectrum disorder in school-aged children with gender dysphoria: A comparison to clinical controls. Clinical Practice in Pediatric Psychology, 7(4), 383","DOI":"10.1037\/cpp0000303"},{"issue":"6","key":"4698_CR24","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.jaac.2017.03.013","volume":"56","author":"R Loomes","year":"2017","unstructured":"Loomes, R., Hull, L., & Mandy, W. P. L. (2017). What is the male-to-female ratio in autism spectrum disorder? A systematic review and meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry, 56(6), 466\u2013474.","journal-title":"Journal of the American Academy of Child & Adolescent Psychiatry"},{"issue":"4","key":"4698_CR25","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1007\/s10803-018-3863-8","volume":"49","author":"A Nordahl-Hansen","year":"2019","unstructured":"Nordahl-Hansen, A., Cicchetti, D. V., & \u00d8ien, R. A. (2019). A review update on gender dysphoria and ASD and response to corrections. Journal of Autism and Developmental Disorders, 49(4), 1745\u20131748.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"5","key":"4698_CR26","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1089\/lgbt.2015.0070","volume":"3","author":"DE Shumer","year":"2016","unstructured":"Shumer, D. E., Reisner, S. L., Edwards-Leeper, L., & Tishelman, A. (2016). Evaluation of Asperger syndrome in youth presenting to a gender dysphoria clinic. LGBT Health, 3(5), 387\u2013390.","journal-title":"LGBT Health"},{"issue":"8","key":"4698_CR27","doi-asserted-by":"publisher","first-page":"2628","DOI":"10.1007\/s10803-015-2413-x","volume":"45","author":"E Skagerberg","year":"2015","unstructured":"Skagerberg, E., Di Ceglie, D., & Carmichael, P. (2015). Brief report: Autistic features in children and adolescents with gender dysphoria. Journal of Autism and Developmental Disorders, 45(8), 2628\u20132632.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"3","key":"4698_CR28","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1542\/peds.2011-0907","volume":"129","author":"NP Spack","year":"2012","unstructured":"Spack, N. P., Edwards-Leeper, L., Feldman, H. A., Leibowitz, S., Mandel, F., Diamond, D. A., et al. (2012). Children and adolescents with gender identity disorder referred to a pediatric medical center. Pediatrics, 129(3), 418\u2013425.","journal-title":"Pediatrics"},{"key":"4698_CR29","doi-asserted-by":"crossref","unstructured":"Strang, J. F., Meagher, H., Kenworthy, L., de Vries, A. L., Menvielle, E., Leibowitz, S.,... & Pleak, R. R. (2018). Initial clinical guidelines for co-occurring autism spectrum disorder and gender dysphoria or incongruence in adolescents. Journal of Clinical Child & Adolescent Psychology, 47(1), 105\u2013115.","DOI":"10.1080\/15374416.2016.1228462"},{"issue":"2","key":"4698_CR30","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/j.1753-4887.1981.tb06734.x","volume":"39","author":"JM Tanner","year":"1981","unstructured":"Tanner, J. M. (1981). Growth and maturation during adolescence. Nutrition Reviews, 39(2), 43\u201355.","journal-title":"Nutrition Reviews"},{"issue":"12","key":"4698_CR31","doi-asserted-by":"publisher","first-page":"4007","DOI":"10.1007\/s10803-018-3603-0","volume":"48","author":"JL Turban","year":"2018","unstructured":"Turban, J. L. (2018). Potentially reversible social deficits among transgender youth. Journal of Autism and Developmental Disorders, 48(12), 4007\u20134009.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"2","key":"4698_CR32","doi-asserted-by":"publisher","first-page":"e20191725","DOI":"10.1542\/peds.2019-1725","volume":"145","author":"JL Turban","year":"2020","unstructured":"Turban, J. L., King, D., Carswell, J. M., & Keuroghlian, A. S. (2020). Pubertal suppression for transgender youth and risk of suicidal ideation. Pediatrics, 145(2), e20191725.","journal-title":"Pediatrics"},{"key":"4698_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaac.2017.10.018","volume":"57","author":"JL Turban","year":"2018","unstructured":"Turban, J. L., & van Schalkwyk, G. I. (2018). \u201cGender dysphoria\u201d and autism spectrum disorder: Is the link real? Journal of the American Academy of Child & Adolescent Psychiatry., 57, 1.","journal-title":"Journal of the American Academy of Child & Adolescent Psychiatry."},{"issue":"2","key":"4698_CR34","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1177\/1359104518804311","volume":"24","author":"J Twist","year":"2019","unstructured":"Twist, J., & de Graaf, N. M. (2019). Gender diversity and non-binary presentations in young people attending the United Kingdom\u2019s National Gender Identity Development Service. Clinical Child Psychology and Psychiatry, 24(2), 277\u2013290.","journal-title":"Clinical Child Psychology and Psychiatry"},{"issue":"5","key":"4698_CR36","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1007\/s10803-017-3417-5","volume":"48","author":"AI Van der Miesen","year":"2018","unstructured":"Van der Miesen, A. I., de Vries, A. L., Steensma, T. D., & Hartman, C. A. (2018). Autistic symptoms in children and adolescents with gender dysphoria. Journal of Autism and Developmental Disorders, 48(5), 1537\u20131548.","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"1","key":"4698_CR35","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3109\/09540261.2015.1111199","volume":"28","author":"AI Van Der Miesen","year":"2016","unstructured":"Van Der Miesen, A. I., Hurley, H., & De Vries, A. L. (2016). Gender dysphoria and autism spectrum disorder: A narrative review. International Review of Psychiatry, 28(1), 70\u201380.","journal-title":"International Review of Psychiatry"},{"issue":"3","key":"4698_CR38","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1016\/j.ridd.2011.12.017","volume":"33","author":"S Wigham","year":"2012","unstructured":"Wigham, S., McConachie, H., Tandos, J., Le Couteur, A. S., & Gateshead Millennium Study Core Team. (2012). The reliability and validity of the Social Responsiveness Scale in a UK general child population. Research in Developmental Disabilities, 33(3), 944\u2013995.","journal-title":"Research in Developmental Disabilities"},{"issue":"2","key":"4698_CR39","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1080\/0092623X.2011.611219","volume":"38","author":"KJ Zucker","year":"2012","unstructured":"Zucker, K. J., Bradley, S. J., Owen-Anderson, A., Kibblewhite, S. J., Wood, H., Singh, D., et al. (2012). Demographics, behavior problems, and psychosexual characteristics of adolescents with gender identity disorder or transvestic fetishism. Journal of Sex & Marital Therapy, 38(2), 151\u2013189.","journal-title":"Journal of Sex & Marital Therapy"},{"key":"4698_CR40","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/978-1-4614-7441-8_9","volume-title":"Gender dysphoria and disorders of sex development","author":"KJ Zucker","year":"2014","unstructured":"Zucker, K. J., Wood, H., & VanderLaan, D. P. (2014). Models of psychopathology in children and adolescents with gender dysphoria. In T. D. Steensma, B. P. C. Kreukels, & A. L. C. de Vries (Eds.), Gender dysphoria and disorders of sex development (pp. 171\u2013192). Boston, MA: Springer."}],"container-title":["Journal of Autism and Developmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10803-020-04698-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10803-020-04698-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10803-020-04698-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:12:32Z","timestamp":1631751152000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10803-020-04698-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,16]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["4698"],"URL":"https:\/\/doi.org\/10.1007\/s10803-020-04698-8","relation":{},"ISSN":["0162-3257","1573-3432"],"issn-type":[{"value":"0162-3257","type":"print"},{"value":"1573-3432","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,16]]},"assertion":[{"value":"16 September 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}