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Existing QoL measures often focus on health-related QoL in neurotypical populations or were developed specifically for autism. The CFQL was designed to bridge this gap. The present study describes evaluation of the second revision of the CFQL - the CFQL-3\/AFQL-3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Psychometric evaluation was conducted in two samples: a large validation sample and a clinical intervention sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Results indicated a clear factor structure, measurement invariance across demographic and clinical factors, good scale and conditional reliability, adequate or better test-retest stability, good construct validity, and good sensitivity to change during behavioral intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The CFQL-3\/AFQL-3 may be a useful clinical and research measure for QoL in clinical and research settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10803-026-07554-3","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T02:45:12Z","timestamp":1790563512000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive Psychometric Evaluation of the Child\/Adult and Family Quality of Life Scale : Third Edition"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6951-2667","authenticated-orcid":false,"given":"Thomas W.","family":"Frazier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nissa","family":"Van Etten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Richard M.","family":"Kubina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Knaebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Frazier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yagnesh","family":"Vadgama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lacey","family":"Chetcuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Uljarevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"issue":"7","key":"7554_CR1","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1177\/1362361317714988","volume":"22","author":"M Ayres","year":"2018","unstructured":"Ayres, M., Parr, J. 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Dr. Frazier has received funding or research support from, acted as a consultant to, received travel support from, and\/or received a speaker\u2019s honorarium from the PTEN Research Foundation, SYNGAP Research Fund, Malan Syndrome Foundation, ADNP Kids Research Foundation, Quadrant Biosciences, Autism Speaks, Impel NeuroPharma, F. Hoffmann-La Roche AG Pharmaceuticals, the Cole Family Research Fund, Simons Foundation, Ingalls Foundation, Forest Laboratories, Ecoeos, IntegraGen, Kugona LLC, Shire Development, Bristol-Myers Squibb, Roche Pharma, MaraBio, Scioto Biosciences, National Institutes of Health, and the Brain and Behavior Research Foundation, has equity options in Quadrant Biosciences\/Autism Analytica, MaraBio, and Springtide, and has an investor stake in Autism EYES LLC, iSCAN-R, and AI-Measures. He is employed by CentralReach which owns the CFQL-3 \/ AFQL-3. Dr. Uljarevic has an investor stake in iSCAN-R and AI-Measures. Drs. Van Etten and Kubina and Mr. Vadgama and Knaebel and Mrs. Frazier are employed by CentralReach, which owns the CFQL-3 \/ AFQL-3. Dr. Chetcuti\u2019s research effort was supported by the Hilibrand Foundation. No other authors have conflicts of interest to disclose relevant to this manuscript.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}