{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T04:36:25Z","timestamp":1759638985738,"version":"3.37.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81571407"],"award-info":[{"award-number":["81571407"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Assist Reprod Genet"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1007\/s10815-019-01627-2","type":"journal-article","created":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T09:07:50Z","timestamp":1575450470000},"page":"119-126","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Tauroursodeoxycholic acid (TUDCA) enhanced intracytoplasmic sperm injection (ICSI) embryo developmental competence by ameliorating endoplasmic reticulum (ER) stress and inhibiting apoptosis"],"prefix":"10.1007","volume":"37","author":[{"given":"Tengfei","family":"Deng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juanke","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hengtao","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobing","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuilian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,4]]},"reference":[{"key":"1627_CR1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.rbmo.2018.01.006","volume":"36","author":"MJ Faddy","year":"2018","unstructured":"Faddy MJ, Gosden MD, Gosden RG. A demographic projection of the contribution of assisted reproductive technologies to world population growth. Reprod Biomed Online. 2018;36:455\u20138.","journal-title":"Reprod Biomed Online."},{"key":"1627_CR2","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1177\/1933719111398148","volume":"18","author":"K Singh","year":"2011","unstructured":"Singh K, Jaiswal D. Human male infertility: a complex multifactorial phenotype. Reprod Sci. 2011;18:418\u201325.","journal-title":"Reprod Sci."},{"key":"1627_CR3","first-page":"194","volume":"22","author":"P Rubino","year":"2016","unstructured":"Rubino P, Vigano P, Luddi A, Piomboni P. The ICSI procedure from past to future: a systematic review of the more controversial aspects. Hum Reprod Update. 2016;22:194\u2013227.","journal-title":"Hum Reprod Update."},{"key":"1627_CR4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/S0967199411000694","volume":"21","author":"R Khoueiry","year":"2013","unstructured":"Khoueiry R, Ibala-Romdhane S, Al-Khtib M, Blachere T, Lornage J, Guerin JF, et al. Abnormal methylation of KCNQ1OT1 and differential methylation of H19 imprinting control regions in human ICSI embryos. Zygote. 2013;21:129\u201338.","journal-title":"Zygote."},{"key":"1627_CR5","doi-asserted-by":"crossref","first-page":"e0187869","DOI":"10.1371\/journal.pone.0187869","volume":"12","author":"L Tang","year":"2017","unstructured":"Tang L, Liu Z, Zhang R, Su C, Yang W, Yao Y, et al. Imprinting alterations in sperm may not significantly influence ART outcomes and imprinting patterns in the cord blood of offspring. PLoS One. 2017;12:e0187869.","journal-title":"PLoS One."},{"key":"1627_CR6","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/humrep\/dex366","volume":"33","author":"C Choux","year":"2018","unstructured":"Choux C, Binquet C, Carmignac V, Bruno C, Chapusot C, Barberet J, et al. The epigenetic control of transposable elements and imprinted genes in newborns is affected by the mode of conception: ART versus spontaneous conception without underlying infertility. Hum Reprod. 2018;33:331\u201340.","journal-title":"Hum Reprod."},{"key":"1627_CR7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1055\/s-0032-1320013","volume":"30","author":"DE Marchesi","year":"2012","unstructured":"Marchesi DE, Qiao J, Feng HL. Embryo manipulation and imprinting. Semin Reprod Med. 2012;30:323\u201334.","journal-title":"Semin Reprod Med."},{"key":"1627_CR8","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1017\/S2040174417000228","volume":"8","author":"M Chen","year":"2017","unstructured":"Chen M, Heilbronn LK. The health outcomes of human offspring conceived by assisted reproductive technologies (ART). J Dev Orig Health Dis. 2017;8:388\u2013402.","journal-title":"J Dev Orig Health Dis."},{"key":"1627_CR9","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s10815-019-01474-1","volume":"36","author":"C Vlachopoulos","year":"2019","unstructured":"Vlachopoulos C, Kosteria I, Sakka S, Gkourogianni A, Terentes-Printzios D, Koutagiar I, et al. PCSK9 and Lp(a) levels of children born after assisted reproduction technologies. J Assist Reprod Genet. 2019;36:1091\u20139.","journal-title":"J Assist Reprod Genet."},{"key":"1627_CR10","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/molehr\/6.9.861","volume":"6","author":"DS Cram","year":"2000","unstructured":"Cram DS, Song B, McLachlan RI, Trounson AO. CAG trinucleotide repeats in the androgen receptor gene of infertile men exhibit stable inheritance in female offspring conceived after ICSI. Mol Hum Reprod. 2000;6:861\u20136.","journal-title":"Mol Hum Reprod."},{"key":"1627_CR11","doi-asserted-by":"crossref","first-page":"F111","DOI":"10.1530\/REP-17-0357","volume":"154","author":"DF Salamone","year":"2017","unstructured":"Salamone DF, Canel NG, Rodriguez MB. Intracytoplasmic sperm injection in domestic and wild mammals. Reproduction. 2017;154:F111\u201324.","journal-title":"Reproduction."},{"key":"1627_CR12","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1017\/S096719941600037X","volume":"25","author":"ME Arias","year":"2017","unstructured":"Arias ME, Sanchez-Villalba E, Delgado A, Felmer R. Effect of transfection and co-incubation of bovine sperm with exogenous DNA on sperm quality and functional parameters for its use in sperm-mediated gene transfer. Zygote. 2017;25:85\u201397.","journal-title":"Zygote."},{"issue":"675-82","key":"1627_CR13","first-page":"e1","volume":"81","author":"HT Jo","year":"2014","unstructured":"Jo HT, Bang JI, Kim SS, Choi BH, Jin JI, Kim HL, et al. Production of female bovine embryos with sex-sorted sperm using intracytoplasmic sperm injection: efficiency and in vitro developmental competence. Theriogenology. 2014;81(675-82):e1.","journal-title":"Theriogenology."},{"key":"1627_CR14","doi-asserted-by":"crossref","first-page":"F51","DOI":"10.1530\/REP-18-0011","volume":"156","author":"CL O\u2019Neill","year":"2018","unstructured":"O\u2019Neill CL, Chow S, Rosenwaks Z, Palermo GD. Development of ICSI. Reproduction. 2018;156:F51\u20138.","journal-title":"Reproduction."},{"key":"1627_CR15","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1095\/biolreprod52.4.709","volume":"52","author":"Y Kimura","year":"1995","unstructured":"Kimura Y, Yanagimachi R. Intracytoplasmic sperm injection in the mouse. Biol Reprod. 1995;52:709\u201320.","journal-title":"Biol Reprod."},{"key":"1627_CR16","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s10815-018-1174-9","volume":"35","author":"RM Salgado","year":"2018","unstructured":"Salgado RM, Brom-de-Luna JG, Resende HL, Canesin HS, Hinrichs K. Lower blastocyst quality after conventional vs. Piezo ICSI in the horse reflects delayed sperm component remodeling and oocyte activation. J Assist Reprod Genet. 2018;35:825\u201340.","journal-title":"J Assist Reprod Genet"},{"key":"1627_CR17","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1530\/REP-06-0358","volume":"133","author":"Y Yu","year":"2007","unstructured":"Yu Y, Ding C, Wang E, Chen X, Li X, Zhao C, et al. Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis. Reproduction. 2007;133:947\u201354.","journal-title":"Reproduction."},{"key":"1627_CR18","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3389\/fcell.2019.00123","volume":"7","author":"L Sampieri","year":"2019","unstructured":"Sampieri L, Di Giusto P, Alvarez C. CREB3 transcription factors: ER-Golgi stress transducers as hubs for cellular homeostasis. Front Cell Dev Biol. 2019;7:123.","journal-title":"Front Cell Dev Biol."},{"key":"1627_CR19","doi-asserted-by":"crossref","first-page":"711","DOI":"10.2217\/epi-2016-0160","volume":"9","author":"S Khan","year":"2017","unstructured":"Khan S, Komarya SK, Jena G. Phenylbutyrate and beta-cell function: contribution of histone deacetylases and ER stress inhibition. Epigenomics. 2017;9:711\u201320.","journal-title":"Epigenomics."},{"key":"1627_CR20","doi-asserted-by":"crossref","first-page":"735","DOI":"10.2174\/1566524015666150921105453","volume":"15","author":"WS Lee","year":"2015","unstructured":"Lee WS, Yoo WH, Chae HJ. ER stress and autophagy. Curr Mol Med. 2015;15:735\u201345.","journal-title":"Curr Mol Med."},{"key":"1627_CR21","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1071\/RD18203","volume":"31","author":"P Qu","year":"2019","unstructured":"Qu P, Zhao Y, Wang R, Zhang Y, Li L, Fan J, et al. Extracellular vesicles derived from donor oviduct fluid improved birth rates after embryo transfer in mice. Reprod Fertil Dev. 2019;31:324\u201332.","journal-title":"Reprod Fertil Dev."},{"key":"1627_CR22","doi-asserted-by":"crossref","first-page":"e0174535","DOI":"10.1371\/journal.pone.0174535","volume":"12","author":"P Qu","year":"2017","unstructured":"Qu P, Qing S, Liu R, Qin H, Wang W, Qiao F, et al. Effects of embryo-derived exosomes on the development of bovine cloned embryos. PLoS One. 2017;12:e0174535.","journal-title":"PLoS One."},{"key":"1627_CR23","doi-asserted-by":"crossref","unstructured":"Qu P, Zuo Z, Liu Z, Niu Z, Zhang Y, Du Y, et al. Sperm-borne small RNA regulate alpha-tubulin acetylation and epigenetic modification of early bovine somatic cell nuclear transfer embryos. Mol Hum Reprod. 2019.","DOI":"10.1093\/molehr\/gaz023"},{"key":"1627_CR24","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1017\/S0967199419000200","volume":"27","author":"L Jia","year":"2019","unstructured":"Jia L, Ding B, Shen C, Luo S, Zhang Y, Zhou L, et al. Use of oocytes selected by brilliant cresyl blue staining enhances rabbit cloned embryo development in vitro. Zygote. 2019;27:166\u201372.","journal-title":"Zygote."},{"key":"1627_CR25","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.rbmo.2017.02.001","volume":"34","author":"RL Kelley","year":"2017","unstructured":"Kelley RL, Gardner DK. In vitro culture of individual mouse preimplantation embryos: the role of embryo density, microwells, oxygen, timing and conditioned media. Reprod Biomed Online. 2017;34:441\u201354.","journal-title":"Reprod Biomed Online."},{"key":"1627_CR26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1387\/ijdb.180355ks","volume":"63","author":"J Bradley","year":"2019","unstructured":"Bradley J, Swann K. Mitochondria and lipid metabolism in mammalian oocytes and early embryos. Int J Dev Biol. 2019;63:93\u2013103.","journal-title":"Int J Dev Biol."},{"key":"1627_CR27","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1210\/me.2011-1362","volume":"26","author":"LL Wu","year":"2012","unstructured":"Wu LL, Russell DL, Norman RJ, Robker RL. Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion, mitochondrial membrane potential (DeltaPsi m), and embryo development. Mol Endocrinol. 2012;26:562\u201373.","journal-title":"Mol Endocrinol."},{"key":"1627_CR28","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00441-015-2124-9","volume":"363","author":"KE Latham","year":"2016","unstructured":"Latham KE. Stress signaling in mammalian oocytes and embryos: a basis for intervention and improvement of outcomes. Cell Tissue Res. 2016;363:159\u201367.","journal-title":"Cell Tissue Res."},{"key":"1627_CR29","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1128\/MCB.00779-06","volume":"26","author":"S Luo","year":"2006","unstructured":"Luo S, Mao C, Lee B, Lee AS. GRP78\/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development. Mol Cell Biol. 2006;26:5688\u201397.","journal-title":"Mol Cell Biol."},{"key":"1627_CR30","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.repbio.2016.10.003","volume":"16","author":"T Lin","year":"2016","unstructured":"Lin T, Lee JE, Oqani RK, Kim SY, Cho ES, Jeong YD, et al. Tauroursodeoxycholic acid improves pre-implantation development of porcine SCNT embryo by endoplasmic reticulum stress inhibition. Reprod Biol. 2016;16:269\u201378.","journal-title":"Reprod Biol."},{"key":"1627_CR31","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s11626-018-0308-9","volume":"55","author":"O Ullah","year":"2019","unstructured":"Ullah O, Li Z, Ali I, Xu L, Liu H, Jin HZ, et al. Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. In Vitro Cell Dev Biol Anim. 2019;55:82\u201393.","journal-title":"In Vitro Cell Dev Biol Anim."},{"key":"1627_CR32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1262\/jrd.2017-055","volume":"64","author":"I Ali","year":"2018","unstructured":"Ali I, Liu HX, Zhong-Shu L, Dong-Xue M, Xu L, Shah SZA, et al. Reduced glutathione alleviates tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. J Reprod Dev. 2018;64:15\u201324.","journal-title":"J Reprod Dev."},{"key":"1627_CR33","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1002\/mrd.20563","volume":"74","author":"Y Xie","year":"2007","unstructured":"Xie Y, Wang F, Puscheck EE, Rappolee DA. Pipetting causes shear stress and elevation of phosphorylated stress-activated protein kinase\/jun kinase in preimplantation embryos. Mol Reprod Dev. 2007;74:1287\u201394.","journal-title":"Mol Reprod Dev."},{"key":"1627_CR34","doi-asserted-by":"crossref","first-page":"43","DOI":"10.12717\/DR.2019.23.1.043","volume":"23","author":"YR Park","year":"2019","unstructured":"Park YR, Park HB, Kim MJ, Jung BD, Lee S, Park CK, et al. Effects of endoplasmic reticulum stress inhibitor treatment during the micromanipulation of somatic cell nuclear transfer in porcine oocytes. Dev Reprod. 2019;23:43\u201354.","journal-title":"Dev Reprod."},{"key":"1627_CR35","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1016\/j.bbamcr.2013.06.028","volume":"1833","author":"R Sano","year":"2013","unstructured":"Sano R, Reed JC. ER stress-induced cell death mechanisms. Biochim Biophys Acta. 2013;1833:3460\u201370.","journal-title":"Biochim Biophys Acta."},{"key":"1627_CR36","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.repbio.2015.01.004","volume":"15","author":"T Lin","year":"2015","unstructured":"Lin T, Diao YF, Kang JW, Lee JE, Kim DK, Jin DI. Tauroursodeoxycholic acid improves the implantation and live-birth rates of mouse embryos. Reprod Biol. 2015;15:101\u20135.","journal-title":"Reprod Biol."},{"key":"1627_CR37","doi-asserted-by":"crossref","first-page":"e0202962","DOI":"10.1371\/journal.pone.0202962","volume":"13","author":"M Mochizuki","year":"2018","unstructured":"Mochizuki M, Miyagi K, Kishigami S. Optimizing treatment of tauroursodeoxycholic acid to improve embryonic development after in vitro maturation of cumulus-free oocytes in mice. PLoS One. 2018;13:e0202962.","journal-title":"PLoS One."},{"key":"1627_CR38","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cryobiol.2014.12.001","volume":"70","author":"N Zhao","year":"2015","unstructured":"Zhao N, Liu XJ, Li JT, Zhang L, Fu Y, Zhang YJ, et al. Endoplasmic reticulum stress inhibition is a valid therapeutic strategy in vitrifying oocytes. Cryobiology. 2015;70:48\u201352.","journal-title":"Cryobiology."},{"key":"1627_CR39","doi-asserted-by":"crossref","first-page":"e0187717","DOI":"10.1371\/journal.pone.0187717","volume":"12","author":"N Dicks","year":"2017","unstructured":"Dicks N, Bohrer RC, Gutierrez K, Michalak M, Agellon LB, Bordignon V. Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos. PLoS One. 2017;12:e0187717.","journal-title":"PLoS One."},{"key":"1627_CR40","doi-asserted-by":"crossref","first-page":"6773","DOI":"10.1038\/s41598-017-07185-w","volume":"7","author":"XX Li","year":"2017","unstructured":"Li XX, Diao YF, Wei HJ, Wang SY, Cao XY, Zhang YF, et al. Tauroursodeoxycholic acid enhances the development of porcine embryos derived from in vitro-matured oocytes and evaporatively dried spermatozoa. Sci Rep. 2017;7:6773.","journal-title":"Sci Rep."},{"key":"1627_CR41","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ab.2011.05.033","volume":"416","author":"E Wydooghe","year":"2011","unstructured":"Wydooghe E, Vandaele L, Beek J, Favoreel H, Heindryckx B, De Sutter P, et al. Differential apoptotic staining of mammalian blastocysts based on double immunofluorescent CDX2 and active caspase-3 staining. Anal Biochem. 2011;416:228\u201330.","journal-title":"Anal Biochem."},{"key":"1627_CR42","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s10815-019-01424-x","volume":"36","author":"IV Ilina","year":"2019","unstructured":"Ilina IV, Khramova YV, Filatov MA, Sitnikov DS. Femtosecond laser is effective tool for zona pellucida engraving and tagging of preimplantation mammalian embryos. J Assist Reprod Genet. 2019;36:1251\u201361.","journal-title":"J Assist Reprod Genet."}],"container-title":["Journal of Assisted Reproduction and Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-019-01627-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10815-019-01627-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-019-01627-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T01:45:52Z","timestamp":1606959952000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10815-019-01627-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,4]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["1627"],"URL":"https:\/\/doi.org\/10.1007\/s10815-019-01627-2","relation":{},"ISSN":["1058-0468","1573-7330"],"issn-type":[{"type":"print","value":"1058-0468"},{"type":"electronic","value":"1573-7330"}],"subject":[],"published":{"date-parts":[[2019,12,4]]},"assertion":[{"value":"25 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Animal Care and Use Committee of Zhengzhou University approved all procedures related to the use of and experimentation on animals.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}