{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:46:48Z","timestamp":1740124008845,"version":"3.37.3"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["19411961100"],"award-info":[{"award-number":["19411961100"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Assist Reprod Genet"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1007\/s10815-024-03032-w","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T05:02:24Z","timestamp":1706677344000},"page":"727-737","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["lncRNA TTTY14 participates in the progression of repeated implantation failure by regulating the miR-6088\/SEMA5A axis"],"prefix":"10.1007","volume":"41","author":[{"given":"Lingzhu","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuju","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5603-6163","authenticated-orcid":false,"given":"Qingqing","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"issue":"1","key":"3032_CR1","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.rbmo.2013.08.011","volume":"28","author":"C Coughlan","year":"2014","unstructured":"Coughlan C, et al. Recurrent implantation failure: definition and management. Reprod Biomed Online. 2014;28(1):14\u201338.","journal-title":"Reprod Biomed Online"},{"issue":"5","key":"3032_CR2","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/j.fertnstert.2012.03.033","volume":"97","author":"N Laufer","year":"2012","unstructured":"Laufer N, Simon A. Recurrent implantation failure: current update and clinical approach to an ongoing challenge. Fertil Steril. 2012;97(5):1019\u201320.","journal-title":"Fertil Steril"},{"key":"3032_CR3","doi-asserted-by":"publisher","first-page":"118181","DOI":"10.1016\/j.lfs.2020.118181","volume":"258","author":"R Pourakbari","year":"2020","unstructured":"Pourakbari R, et al. Cell therapy in female infertility-related diseases: emphasis on recurrent miscarriage and repeated implantation failure. Life Sci. 2020;258:118181.","journal-title":"Life Sci"},{"issue":"5","key":"3032_CR4","doi-asserted-by":"publisher","first-page":"e13376","DOI":"10.1111\/aji.13376","volume":"85","author":"K Kuroda","year":"2021","unstructured":"Kuroda K, et al. Analysis of the risk factors and treatment for repeated implantation failure: OPtimization of thyroid function, IMmunity, and Uterine Milieu (OPTIMUM) treatment strategy. Am J Reprod Immunol. 2021;85(5):e13376.","journal-title":"Am J Reprod Immunol"},{"issue":"1","key":"3032_CR5","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1159\/000484887","volume":"44","author":"L Liu","year":"2017","unstructured":"Liu L, et al. Altered circular RNA expression in patients with repeated implantation failure. Cell Physiol Biochem. 2017;44(1):303\u201313.","journal-title":"Cell Physiol Biochem"},{"key":"3032_CR6","doi-asserted-by":"crossref","unstructured":"Chen Q et al. Real-time in vivo magnetic induction tomography in rabbits: a feasibility study. 2020;32(3).","DOI":"10.1088\/1361-6501\/abc579"},{"issue":"2","key":"3032_CR7","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1080\/19396368.2018.1563844","volume":"65","author":"D Li","year":"2019","unstructured":"Li D, et al. Preliminary functional inquiry of lncRNA ENST00000433673 in embryo implantation using bioinformatics analysis. Syst Biology Reproductive Med. 2019;65(2):164\u201373.","journal-title":"Syst Biology Reproductive Med"},{"issue":"3","key":"3032_CR8","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1080\/14647273.2017.1324180","volume":"21","author":"C Shi","year":"2018","unstructured":"Shi C, et al. Diverse endometrial mRNA signatures during the window of implantation in patients with repeated implantation failure. Hum Fertility. 2018;21(3):183\u201394.","journal-title":"Hum Fertility"},{"issue":"2","key":"3032_CR9","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s10815-018-1326-y","volume":"36","author":"AB Paul","year":"2019","unstructured":"Paul AB, Sadek ST, Mahesan AM. The role of microRNAs in human embryo implantation: a review. J Assist Reprod Genet. 2019;36(2):179\u201387.","journal-title":"J Assist Reprod Genet"},{"key":"3032_CR10","doi-asserted-by":"publisher","first-page":"144056","DOI":"10.1016\/j.gene.2019.144056","volume":"720","author":"H Xu","year":"2019","unstructured":"Xu H, et al. Genome-wide analysis of long noncoding RNAs, microRNAs, and mRNAs forming a competing endogenous RNA network in repeated implantation failure. Gene. 2019;720:144056.","journal-title":"Gene"},{"issue":"10","key":"3032_CR11","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.7150\/ijbs.25081","volume":"14","author":"C Feng","year":"2018","unstructured":"Feng C, et al. Construction of implantation failure related lncRNA-mRNA network and identification of lncRNA biomarkers for predicting endometrial receptivity. Int J Biol Sci. 2018;14(10):1361.","journal-title":"Int J Biol Sci"},{"key":"3032_CR12","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/978-1-4939-3578-9_5","volume":"1418","author":"E Clough","year":"2016","unstructured":"Clough E, Barrett T. The gene expression omnibus database. Methods Mol Biol. 2016;1418:93\u2013110.","journal-title":"Methods Mol Biol"},{"issue":"1","key":"3032_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13018-020-01655-0","volume":"15","author":"C Liu","year":"2020","unstructured":"Liu C, et al. MicroRNA-1202 plays a vital role in osteoarthritis via KCNQ1OT1 has-mir-1202-ETS1 regulatory pathway. J Orthop Surg Res. 2020;15(1):1\u20139.","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"3032_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.compbiomed.2013.12.002","volume":"46","author":"D Yang","year":"2014","unstructured":"Yang D, Parrish RS, Brock GN. Empirical evaluation of consistency and accuracy of methods to detect differentially expressed genes based on microarray data. Computers in Biology & Medicine. 2014;46(1):1\u201310.","journal-title":"Computers in Biology & Medicine"},{"issue":"6","key":"3032_CR15","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1093\/bioinformatics\/bts034","volume":"28","author":"JT Leek","year":"2012","unstructured":"Leek JT, et al. The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics. 2012;28(6):882\u20133.","journal-title":"Bioinformatics"},{"key":"3032_CR16","unstructured":"Smyth GK et al. LIMMA: linear models for microarray data. In Bioinformatics and computational biology solutions using R and bioconductor. Statistics for Biology and Health. 2005."},{"issue":"1","key":"3032_CR17","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1186\/s12864-021-07510-8","volume":"22","author":"Y Dai","year":"2021","unstructured":"Dai Y, et al. Gene co-expression network analysis reveals key pathways and hub genes in Chinese cabbage (Brassica rapa L.) during vernalization. BMC Genomics. 2021;22(1):236.","journal-title":"BMC Genomics"},{"issue":"5","key":"3032_CR18","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"G Yu","year":"2012","unstructured":"Yu G, et al. clusterProfiler: an R package for comparing biological themes among gene clusters. Omics. 2012;16(5):284\u20137.","journal-title":"Omics"},{"issue":"Database issue","key":"3032_CR19","doi-asserted-by":"publisher","first-page":"D1049","DOI":"10.1093\/nar\/gku1179","volume":"43","author":"Gene Ontology Consortium","year":"2015","unstructured":"Gene Ontology Consortium. Going forward. Nucleic Acids Res. 2015;43(Database issue):D1049\u201356.","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"3032_CR20","doi-asserted-by":"publisher","first-page":"D353","DOI":"10.1093\/nar\/gkw1092","volume":"45","author":"M Kanehisa","year":"2017","unstructured":"Kanehisa M, et al. KEGG: new perspectives on genomes, pathways, diseases and drugs. Nucleic Acids Res. 2017;45(D1):D353\u2013d361.","journal-title":"Nucleic Acids Res"},{"key":"3032_CR21","doi-asserted-by":"publisher","first-page":"779168","DOI":"10.3389\/fonc.2022.779168","volume":"12","author":"G Tanzhu","year":"2022","unstructured":"Tanzhu G, et al. Molecular subtypes and prognostic signature of pyroptosis-related lncRNAs in glioma patients. Front Oncol. 2022;12:779168\u20138.","journal-title":"Front Oncol"},{"key":"3032_CR22","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/978-1-60761-987-1_18","volume":"696","author":"M Kohl","year":"2011","unstructured":"Kohl M, Wiese S, Warscheid B. Cytoscape: software for visualization and analysis of biological networks. Methods Mol Biol. 2011;696:291\u2013303.","journal-title":"Methods Mol Biol"},{"issue":"2","key":"3032_CR23","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1002\/pmic.201200309","volume":"13","author":"X Lei","year":"2013","unstructured":"Lei X, et al. Clustering and overlapping modules detection in PPI network based on IBFO. Proteomics. 2013;13(2):278\u201390.","journal-title":"Proteomics"},{"issue":"5","key":"3032_CR24","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"G Yu","year":"2012","unstructured":"Yu G, et al. clusterProfiler: an R package for comparing biological themes among gene clusters. Omics-a J Integr Biology. 2012;16(5):284\u20137.","journal-title":"Omics-a J Integr Biology"},{"issue":"Database issue","key":"3032_CR25","doi-asserted-by":"publisher","first-page":"D1228","DOI":"10.1093\/nar\/gks1147","volume":"41","author":"K Breuer","year":"2013","unstructured":"Breuer K, et al. InnateDB: systems biology of innate immunity and beyond\u2013recent updates and continuing curation. Nucleic Acids Res. 2013;41(Database issue):D1228\u201333.","journal-title":"Nucleic Acids Res"},{"issue":"8","key":"3032_CR26","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1038\/nmeth.3485","volume":"12","author":"H Dweep","year":"2015","unstructured":"Dweep H, Gretz N. miRWalk2. 0: a comprehensive atlas of microRNA-target interactions. Nat Methods. 2015;12(8):697\u20137.","journal-title":"Nat Methods"},{"issue":"D1","key":"3032_CR27","doi-asserted-by":"publisher","first-page":"D127","DOI":"10.1093\/nar\/gkz757","volume":"48","author":"Y Chen","year":"2020","unstructured":"Chen Y, Wang X. miRDB: an online database for prediction of functional microRNA targets. Nucleic Acids Res. 2020;48(D1):D127\u2013d131.","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"3032_CR28","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.molcel.2007.06.017","volume":"27","author":"A Grimson","year":"2007","unstructured":"Grimson A, et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell. 2007;27(1):91\u2013105.","journal-title":"Mol Cell"},{"issue":"8","key":"3032_CR29","doi-asserted-by":"publisher","first-page":"R90","DOI":"10.1186\/gb-2010-11-8-r90","volume":"11","author":"D Betel","year":"2010","unstructured":"Betel D, et al. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol. 2010;11(8):R90\u20130.","journal-title":"Genome Biol"},{"issue":"11","key":"3032_CR30","doi-asserted-by":"publisher","first-page":"3296","DOI":"10.1007\/s12094-023-03180-y","volume":"25","author":"G Wang","year":"2023","unstructured":"Wang G, et al. A nine-gene signature as prognostic biomarker in gastric cancer by bioinformatics analysis. Clin Transl Oncol. 2023;25(11):3296\u2013306.","journal-title":"Clin Transl Oncol"},{"issue":"22","key":"3032_CR31","doi-asserted-by":"publisher","first-page":"11673","DOI":"10.1093\/nar\/gks901","volume":"40","author":"Charles","year":"2012","unstructured":"Charles, et al. miRmap: Comprehensive prediction of microRNA target repression strength. Nucleic Acids Res. 2012;40(22):11673.","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"3032_CR32","doi-asserted-by":"publisher","first-page":"D231","DOI":"10.1093\/nar\/gkv1270","volume":"44","author":"M Paraskevopoulou","year":"2016","unstructured":"Paraskevopoulou M, et al. DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Res. 2016;44(D1):D231\u20138.","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"3032_CR33","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12955-021-01666-3","volume":"19","author":"Y Ni","year":"2021","unstructured":"Ni Y, et al. The analysis of fertility quality of life and the influencing factors of patients with repeated implantation failure. Health Qual Life Outcomes. 2021;19(1):32.","journal-title":"Health Qual Life Outcomes"},{"issue":"2","key":"3032_CR34","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1093\/humupd\/dmq037","volume":"17","author":"H Cakmak","year":"2011","unstructured":"Cakmak H, Taylor HS. Implantation failure: molecular mechanisms and clinical treatment. Hum Reprod Update. 2011;17(2):242\u201353.","journal-title":"Hum Reprod Update"},{"issue":"21","key":"3032_CR35","doi-asserted-by":"publisher","first-page":"4989","DOI":"10.1523\/JNEUROSCI.4390-03.2004","volume":"24","author":"JL Goldberg","year":"2004","unstructured":"Goldberg JL, et al. An oligodendrocyte lineage-specific semaphorin, Sema5A, inhibits axon growth by retinal ganglion cells. J Neurosci. 2004;24(21):4989\u201399.","journal-title":"J Neurosci"},{"issue":"1","key":"3032_CR36","doi-asserted-by":"publisher","first-page":"45","DOI":"10.2174\/1389201020666190911113611","volume":"21","author":"K Dziobek","year":"2020","unstructured":"Dziobek K, et al. Assessment of the usefulness of the SEMA5A concentration profile changes as a molecular marker in endometrial cancer. Curr Pharm Biotechnol. 2020;21(1):45\u201351.","journal-title":"Curr Pharm Biotechnol"},{"issue":"18","key":"3032_CR37","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.4103\/0366-6999.240808","volume":"131","author":"H Cai","year":"2018","unstructured":"Cai H, et al. MicroRNA dysregulation and steroid hormone receptor expression in uterine tissues of rats with endometriosis during the implantation window. Chin Med J. 2018;131(18):2193.","journal-title":"Chin Med J"},{"issue":"1","key":"3032_CR38","doi-asserted-by":"publisher","first-page":"151","DOI":"10.2131\/jts.38.151","volume":"38","author":"A Honda","year":"2013","unstructured":"Honda A, et al. Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation. J Toxicol Sci. 2013;38(1):151\u20133.","journal-title":"J Toxicol Sci"},{"issue":"5","key":"3032_CR39","doi-asserted-by":"publisher","first-page":"566","DOI":"10.4103\/0366-6999.200550","volume":"130","author":"C Shi","year":"2017","unstructured":"Shi C, et al. Endometrial microRNA signature during the window of implantation changed in patients with repeated implantation failure. Chin Med J. 2017;130(5):566.","journal-title":"Chin Med J"},{"issue":"5","key":"3032_CR40","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.tranon.2019.01.006","volume":"12","author":"R Pandey","year":"2019","unstructured":"Pandey R, et al. Circulating miRNA profiling of women at high risk for ovarian cancer. Translational Oncol. 2019;12(5):714\u201325.","journal-title":"Translational Oncol"},{"issue":"43","key":"3032_CR41","doi-asserted-by":"publisher","first-page":"75007","DOI":"10.18632\/oncotarget.20496","volume":"8","author":"Y Miao","year":"2017","unstructured":"Miao Y, et al. Comprehensive analysis of a novel four-lncRNA signature as a prognostic biomarker for human gastric cancer. Oncotarget. 2017;8(43):75007.","journal-title":"Oncotarget"},{"issue":"1","key":"3032_CR42","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s12958-019-0465-z","volume":"17","author":"MA Bhat","year":"2019","unstructured":"Bhat MA, et al. Genomic evidence of Y chromosome microchimerism in the endometrium during endometriosis and in cases of infertility. Reprod Biol Endocrinol. 2019;17(1):22.","journal-title":"Reprod Biol Endocrinol"},{"issue":"17","key":"3032_CR43","doi-asserted-by":"publisher","first-page":"8227","DOI":"10.1093\/nar\/gkv721","volume":"43","author":"E Kim","year":"2015","unstructured":"Kim E, et al. ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in facioscapulohumeral dystrophy. Nucleic Acids Res. 2015;43(17):8227\u201342.","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"3032_CR44","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1097\/ACO.0000000000000311","volume":"29","author":"M Heesen","year":"2016","unstructured":"Heesen M, Klimek M. Nonobstetric anesthesia during pregnancy. Curr Opin Anaesthesiol. 2016;29(3):297\u2013303.","journal-title":"Curr Opin Anaesthesiol"},{"issue":"4","key":"3032_CR45","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1136\/jmedgenet-2013-102116","volume":"51","author":"LE Docherty","year":"2014","unstructured":"Docherty LE, et al. Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes. J Med Genet. 2014;51(4):229\u201338.","journal-title":"J Med Genet"},{"issue":"2","key":"3032_CR46","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.fertnstert.2021.03.011","volume":"116","author":"EH Yeung","year":"2021","unstructured":"Yeung EH, et al. Conception by fertility treatment and offspring deoxyribonucleic acid methylation. Fertil Steril. 2021;116(2):493\u2013504.","journal-title":"Fertil Steril"}],"container-title":["Journal of Assisted Reproduction and Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03032-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10815-024-03032-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03032-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T07:07:44Z","timestamp":1711004864000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10815-024-03032-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,31]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["3032"],"URL":"https:\/\/doi.org\/10.1007\/s10815-024-03032-w","relation":{},"ISSN":["1058-0468","1573-7330"],"issn-type":[{"type":"print","value":"1058-0468"},{"type":"electronic","value":"1573-7330"}],"subject":[],"published":{"date-parts":[[2024,1,31]]},"assertion":[{"value":"8 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}