{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T21:43:51Z","timestamp":1757454231348,"version":"3.37.3"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004375","name":"Tel Aviv University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004375","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Assist Reprod Genet"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>To investigate treatment approaches for fertility preservation patients, with a focus on timing of oocyte retrieval, and to determine whether their characteristics differ from those of other IVF patients. Additionally, to evaluate the significance of follicle size on triggering day in the context of fertility preservation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This retrospective cohort study was conducted in a tertiary, university-affiliated medical center. It compared 140 matched patients undergoing social fertility preservation to 140 patients undergoing IVF treatment due to male factor infertility.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Patients undergoing fertility preservation received a higher initial gonadotropin dose and had more oocytes retrieved than the control group. Within the fertility preservation cohort, a negative correlation was observed between the rate of large follicles and the number of retrieved oocytes. While there was no significant association between rate of large follicles and oocyte maturation rate in the entire group, age-stratified analysis revealed a negative relationship. Analysis revealed that although traditional treatment determinants such as follicular size and gonadotropin dosing were considered, peak estradiol levels were consistently identified as significant predictors of treatment outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Physicians may modify treatments for fertility preservation, emphasizing a higher gonadotropin dosage to maximize oocyte retrieval. Elevated estradiol levels can serve as a real-time predictive marker for the number of mature oocytes. While treatment strategies can influence outcomes, intrinsic patient factors, particularly baseline ovarian function, remain crucial. These results challenge beliefs regarding the importance of larger follicles and suggest the need for a tailored approach, considering patient age and specific fertility preservation objectives.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10815-024-03138-1","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T02:01:29Z","timestamp":1716170489000},"page":"1863-1870","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oocyte retrieval in social fertility preservation: challenging traditional beliefs on gonadotropin dosing and follicular size"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-0051","authenticated-orcid":false,"given":"Einat Haikin","family":"Herzberger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mor","family":"Semo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Soifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Netanella","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitzan Goren","family":"Gepstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roni","family":"Rahav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattan","family":"Levi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Wiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"issue":"2359\u20132363","key":"3138_CR1","first-page":"e1","volume":"95","author":"B Almog","year":"2011","unstructured":"Almog B, Shehata F, Suissa S, Holzer H, Shalom-Paz E, La Marca A, Muttukrishna S, Blazar A, Hackett R, Nelson SM. Age-related normograms of serum antim\u00fcllerian hormone levels in a population of infertile women: a multicenter study. Fertil Steril. 2011;95(2359\u20132363):e1.","journal-title":"Fertil Steril"},{"key":"3138_CR2","unstructured":"Ash N. Expansion of the health services package for 2022. In: Circular DGS (Ed.): Israeli Ministry of Health. 2022."},{"key":"3138_CR3","unstructured":"ASRM Patient Education Committee. Can i freeze my eggs to use later if i'm not sick? : https:\/\/www.reproductivefacts.org\/news-and-publications\/fact-sheets-and-infographics\/can-i-freeze-my-eggs-to-use-later-if-im-not-sick\/. 2014."},{"key":"3138_CR4","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s12910-022-00774-z","volume":"23","author":"M De Proost","year":"2022","unstructured":"De Proost M, Coene G, Nekkebroeck J, Provoost V. \u2018I feel that injustice is being done to me\u2019: a qualitative study of women\u2019s viewpoints on the (lack of) reimbursement for social egg freezing. 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Egg freezing, fertility and reproductive choice: negotiating responsibility, hope and modern motherhood Emerald Publishing Limited. 2019.","DOI":"10.1108\/9781787564831"},{"key":"3138_CR7","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.rbmo.2015.08.005","volume":"31","author":"JK Bosdou","year":"2015","unstructured":"Bosdou JK, Kolibianakis EM, Venetis CA, Zepiridis L, Chatzimeletiou K, Makedos A, Triantafyllidis S, Masouridou S, Mitsoli A, Tarlatzis B. Is the time interval between HCG administration and oocyte retrieval associated with oocyte retrieval rate? Reprod Biomed Online. 2015;31:625\u201332.","journal-title":"Reprod Biomed Online"},{"key":"3138_CR8","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.fertnstert.2007.02.002","volume":"89","author":"L Engmann","year":"2008","unstructured":"Engmann L, Diluigi A, Schmidt D, Nulsen J, Maier D, Benadiva C. The use of gonadotropin-releasing hormone (GNRH) agonist to induce oocyte maturation after cotreatment with GNRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective randomized controlled study. Fertil Steril. 2008;89:84\u201391. https:\/\/doi.org\/10.1016\/j.fertnstert.2007.02.002.","journal-title":"Fertil Steril"},{"issue":"1618\u20131623","key":"3138_CR9","first-page":"e3","volume":"101","author":"P Fauque","year":"2014","unstructured":"Fauque P, Lehert P, Lamotte M, Bettahar-Lebugle K, Bailly A, Diligent C, Cl\u00e9dat M, Pierrot P, Gu\u00e9n\u00e9dal M-L, Sagot P. Clinical success of intrauterine insemination cycles is affected by the sperm preparation time. 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