{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:15:53Z","timestamp":1791519353086,"version":"4.3.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T00:00:00Z","timestamp":1733443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T00:00:00Z","timestamp":1733443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["P50HD104463"],"award-info":[{"award-number":["P50HD104463"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013224","name":"National Fragile X Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013224","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Assist Reprod Genet"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s10815-024-03337-w","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T05:03:32Z","timestamp":1733461412000},"page":"499-508","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Women\u2019s healthcare providers\u2019 knowledge and practices surrounding fragile-X associated primary ovarian insufficiency (FXPOI)"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6588-7293","authenticated-orcid":false,"given":"Alexandra L.","family":"Singleton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1089-3928","authenticated-orcid":false,"given":"Heather S.","family":"Hipp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Poteet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0963-036X","authenticated-orcid":false,"given":"Emily G.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,6]]},"reference":[{"key":"3337_CR1","doi-asserted-by":"publisher","first-page":"601752","DOI":"10.3389\/fendo.2021.601752","volume":"12","author":"X Jiao","year":"2021","unstructured":"Jiao X, Meng T, Zhai Y, et al. Ovarian reserve markers in premature ovarian insufficiency: within different clinical stages and different etiologies. Front Endocrinol (Lausanne). 2021;12:601752. https:\/\/doi.org\/10.3389\/fendo.2021.601752.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"3337_CR2","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1002\/ajmg.b.32176","volume":"162b","author":"MJ Maenner","year":"2013","unstructured":"Maenner MJ, Baker MW, Broman KW, et al. FMR1 CGG expansions: prevalence and sex ratios. Am J Med Genet B Neuropsychiatr Genet. 2013;162b(5):466\u201373. https:\/\/doi.org\/10.1002\/ajmg.b.32176.","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"9","key":"3337_CR3","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1038\/s41436-021-01177-y","volume":"23","author":"EG Allen","year":"2021","unstructured":"Allen EG, Charen K, Hipp HS, et al. Refining the risk for fragile X-associated primary ovarian insufficiency (FXPOI) by FMR1 CGG repeat size. Genet Med. 2021;23(9):1648\u201355. https:\/\/doi.org\/10.1038\/s41436-021-01177-y.","journal-title":"Genet Med"},{"key":"3337_CR4","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3389\/fgene.2018.00529","volume":"9","author":"DA Fink","year":"2018","unstructured":"Fink DA, Nelson LM, Pyeritz R, et al. Fragile X Associated primary ovarian insufficiency (FXPOI): case report and literature review. Front Genet. 2018;9:529. https:\/\/doi.org\/10.3389\/fgene.2018.00529.","journal-title":"Front Genet"},{"issue":"9","key":"3337_CR5","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1097\/gme.0000000000000658","volume":"23","author":"HS Hipp","year":"2016","unstructured":"Hipp HS, Charen KH, Spencer JB, Allen EG, Sherman SL. Reproductive and gynecologic care of women with fragile X primary ovarian insufficiency (FXPOI). Menopause. 2016;23(9):993\u20139. https:\/\/doi.org\/10.1097\/gme.0000000000000658.","journal-title":"Menopause"},{"issue":"5","key":"3337_CR6","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1093\/humrep\/13.5.1184","volume":"13","author":"GS Conway","year":"1998","unstructured":"Conway GS, Payne NN, Webb J, Murray A, Jacobs PA. Fragile X premutation screening in women with premature ovarian failure. Hum Reprod. 1998;13(5):1184\u20137. https:\/\/doi.org\/10.1093\/humrep\/13.5.1184.","journal-title":"Hum Reprod"},{"key":"3337_CR7","doi-asserted-by":"publisher","first-page":"17065","DOI":"10.1038\/nrdp.2017.65","volume":"3","author":"RJ Hagerman","year":"2017","unstructured":"Hagerman RJ, Berry-Kravis E, Hazlett HC, et al. Fragile X syndrome. Nat Rev Dis Primers. 2017;3:17065. https:\/\/doi.org\/10.1038\/nrdp.2017.65.","journal-title":"Nat Rev Dis Primers"},{"key":"3337_CR8","doi-asserted-by":"publisher","unstructured":"ACOG committee opinion. No. 338: Screening for fragile X syndrome. Obstet Gynecol. 2006;107(6):1483\u20135. https:\/\/doi.org\/10.1097\/00006250-200606000-00059","DOI":"10.1097\/00006250-200606000-00059"},{"key":"3337_CR9","doi-asserted-by":"publisher","unstructured":"Committee Opinion No. 691: Carrier Screening for Genetic Conditions. Obstet Gynecol. 2017;129(3):e41-e55. https:\/\/doi.org\/10.1097\/aog.0000000000001952","DOI":"10.1097\/aog.0000000000001952"},{"issue":"1","key":"3337_CR10","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s10815-022-02671-1","volume":"40","author":"B Poteet","year":"2023","unstructured":"Poteet B, Ali N, Bellcross C, et al. The diagnostic experience of women with fragile X-associated primary ovarian insufficiency (FXPOI). J Assist Reprod Genet. 2023;40(1):179\u201390. https:\/\/doi.org\/10.1007\/s10815-022-02671-1.","journal-title":"J Assist Reprod Genet"},{"key":"3337_CR11","unstructured":"Colleges AoAM. Medical School Graduation Questionnaire All Schools Summary Report. 2023."},{"issue":"1","key":"3337_CR12","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1002\/jgc4.1795","volume":"33","author":"S Kapur","year":"2024","unstructured":"Kapur S, Lichten L, Ali N, Garber KB. Poor recall of genetics curriculum by medical students highlights barriers to use in clinical practice. J Genet Couns. 2024;33(1):179\u201388. https:\/\/doi.org\/10.1002\/jgc4.1795.","journal-title":"J Genet Couns"},{"issue":"5","key":"3337_CR13","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1097\/ACM.0b013e31803e86c5","volume":"82","author":"VC Thurston","year":"2007","unstructured":"Thurston VC, Wales PS, Bell MA, Torbeck L, Brokaw JJ. The current status of medical genetics instruction in US and Canadian medical schools. Acad Med. 2007;82(5):441\u20135. https:\/\/doi.org\/10.1097\/ACM.0b013e31803e86c5.","journal-title":"Acad Med"},{"issue":"11","key":"3337_CR14","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1038\/gim.2014.208","volume":"17","author":"J Plunkett-Rondeau","year":"2015","unstructured":"Plunkett-Rondeau J, Hyland K, Dasgupta S. Training future physicians in the era of genomic medicine: trends in undergraduate medical genetics education. Genet Med. 2015;17(11):927\u201334. https:\/\/doi.org\/10.1038\/gim.2014.208.","journal-title":"Genet Med"},{"key":"3337_CR15","unstructured":"Education ACfGM. ACGME Program Requirements for Graduate Medical Education in Obstetrics and Gynecology. 2023."},{"key":"3337_CR16","unstructured":"Counseling ACfG. Standards of Accreditation for Graduate Programs in Genetic Counseling. 2023."},{"key":"3337_CR17","unstructured":"Counseling ACfG. Practice-Based Competencies for Genetic Counselors. 2023."},{"key":"3337_CR18","unstructured":"Education ACfGM. Data Resource Book Academic Year 2022\u20132023. 2023."}],"container-title":["Journal of Assisted Reproduction and Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03337-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10815-024-03337-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03337-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T13:36:51Z","timestamp":1740749811000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10815-024-03337-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,6]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["3337"],"URL":"https:\/\/doi.org\/10.1007\/s10815-024-03337-w","relation":{},"ISSN":["1058-0468","1573-7330"],"issn-type":[{"value":"1058-0468","type":"print"},{"value":"1573-7330","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,6]]},"assertion":[{"value":"1 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Alexandra Singleton, Heather Hipp, Bonnie Poteet and Emily Allen declare that they have no conflicts of interest. Nadia Ali has received research support from Sanofi Genzyme, Shire Takeda, BioMarin, Amicus, and Pfizer, as well as lecturers\u2019 honoraria from Sanofi Genzyme, BioMarin, Amicus, and Vitaflo. These activities are monitored and in compliance with conflict of interest policies at Emory University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}