{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:52:50Z","timestamp":1791809570885,"version":"4.3.4"},"reference-count":147,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Guangzhou Science and Technology Project","award":["2023A04J1219"],"award-info":[{"award-number":["2023A04J1219"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Assist Reprod Genet"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1007\/s10815-024-03375-4","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T10:24:29Z","timestamp":1736504669000},"page":"707-720","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Copper homeostasis and pregnancy complications: a comprehensive review"],"prefix":"10.1007","volume":"42","author":[{"given":"Tongyu","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanmin","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,10]]},"reference":[{"issue":"11","key":"3375_CR1","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1093\/jn\/109.11.1979","volume":"109","author":"KE Mason","year":"1979","unstructured":"Mason KE. A conspectus of research on copper metabolism and requirements of man. J Nutr. 1979;109(11):1979\u20132066. https:\/\/doi.org\/10.1093\/jn\/109.11.1979.","journal-title":"J Nutr"},{"issue":"10","key":"3375_CR2","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1007\/s00424-020-02412-2","volume":"472","author":"J Chen","year":"2020","unstructured":"Chen J, Jiang Y, Shi H, Peng Y, Fan X, Li C. The molecular mechanisms of copper metabolism and its roles in human diseases. Pflugers Arch. 2020;472(10):1415\u201329. https:\/\/doi.org\/10.1007\/s00424-020-02412-2.","journal-title":"Pflugers Arch"},{"key":"3375_CR3","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3389\/fnagi.2014.00092","volume":"6","author":"GJ Brewer","year":"2014","unstructured":"Brewer GJ. Alzheimer\u2019s disease causation by copper toxicity and treatment with zinc. Front Aging Neurosci. 2014;6:92. https:\/\/doi.org\/10.3389\/fnagi.2014.00092.","journal-title":"Front Aging Neurosci"},{"issue":"4","key":"3375_CR4","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1002\/jat.4252","volume":"42","author":"Q Lu","year":"2022","unstructured":"Lu Q, Zhang Y, Zhao C, Zhang H, Pu Y, Yin L. Copper induces oxidative stress and apoptosis of hippocampal neuron via pCREB\/BDNF\/ and Nrf2\/HO-1\/NQO1 pathway. J Appl Toxicol: JAT. 2022;42(4):694\u2013705. https:\/\/doi.org\/10.1002\/jat.4252.","journal-title":"J Appl Toxicol: JAT"},{"key":"3375_CR5","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/srep00011","volume":"1","author":"F Rose","year":"2011","unstructured":"Rose F, Hodak M, Bernholc J. Mechanism of copper(II)-induced misfolding of Parkinson\u2019s disease protein. Sci Rep. 2011;1:11. https:\/\/doi.org\/10.1038\/srep00011.","journal-title":"Sci Rep"},{"issue":"37","key":"3375_CR6","doi-asserted-by":"publisher","first-page":"14995","DOI":"10.1073\/pnas.1308535110","volume":"110","author":"G Xiao","year":"2013","unstructured":"Xiao G, Fan Q, Wang X, Zhou B. Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding. Proc Natl Acad Sci USA. 2013;110(37):14995\u20135000. https:\/\/doi.org\/10.1073\/pnas.1308535110.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3375_CR7","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/b978-0-444-63233-3.00018-x","volume":"147","author":"MT Lorincz","year":"2018","unstructured":"Lorincz MT. Wilson disease and related copper disorders. Handb Clin Neurol. 2018;147:279\u201392. https:\/\/doi.org\/10.1016\/b978-0-444-63233-3.00018-x.","journal-title":"Handb Clin Neurol"},{"issue":"6","key":"3375_CR8","first-page":"438","volume":"4","author":"R Xu","year":"2008","unstructured":"Xu R, Hajdu CH. Wilson disease and hepatocellular carcinoma. Gastroenterol Hepatol. 2008;4(6):438\u20139.","journal-title":"Gastroenterol Hepatol"},{"key":"3375_CR9","doi-asserted-by":"publisher","unstructured":"Antonucci L, Porcu C, Iannucci G, Balsano C, Barbaro B. Non-Alcoholic fatty liver disease and nutritional implications: special focus on copper. Nutrients. 2017;9(10). https:\/\/doi.org\/10.3390\/nu9101137.","DOI":"10.3390\/nu9101137"},{"issue":"2","key":"3375_CR10","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1007\/s12011-022-03191-w","volume":"201","author":"V Pouresmaeil","year":"2023","unstructured":"Pouresmaeil V, Al Abudi AH, Mahimid AH, Sarafraz Yazdi M, Es-Haghi A. Evaluation of serum selenium and copper levels with inflammatory cytokines and indices of oxidative stress in type 2 diabetes. Biol Trace Elem Res. 2023;201(2):617\u201326. https:\/\/doi.org\/10.1007\/s12011-022-03191-w.","journal-title":"Biol Trace Elem Res"},{"issue":"23","key":"3375_CR11","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.2217\/epi-2023-0230","volume":"15","author":"S Qian","year":"2023","unstructured":"Qian S, Liu J, Liao W, Wang F. METTL3 promotes non-small-cell lung cancer growth and metastasis by inhibiting FDX1 through copper death-associated pri-miR-21-5p maturation. Epigenomics. 2023;15(23):1237\u201355. https:\/\/doi.org\/10.2217\/epi-2023-0230.","journal-title":"Epigenomics"},{"issue":"3","key":"3375_CR12","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/s0041-008x(03)00247-3","volume":"191","author":"C Manzl","year":"2003","unstructured":"Manzl C, Ebner H, K\u00f6ck G, Dallinger R, Krumschnabel G. Copper, but not cadmium, is acutely toxic for trout hepatocytes: short-term effects on energetics and ion homeostasis. Toxicol Appl Pharmacol. 2003;191(3):235\u201344. https:\/\/doi.org\/10.1016\/s0041-008x(03)00247-3.","journal-title":"Toxicol Appl Pharmacol"},{"issue":"1\u20132","key":"3375_CR13","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.tox.2003.11.001","volume":"196","author":"C Manzl","year":"2004","unstructured":"Manzl C, Enrich J, Ebner H, Dallinger R, Krumschnabel G. Copper-induced formation of reactive oxygen species causes cell death and disruption of calcium homeostasis in trout hepatocytes. Toxicology. 2004;196(1\u20132):57\u201364. https:\/\/doi.org\/10.1016\/j.tox.2003.11.001.","journal-title":"Toxicology"},{"issue":"6586","key":"3375_CR14","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1126\/science.abo3959","volume":"375","author":"MA Kahlson","year":"2022","unstructured":"Kahlson MA, Dixon SJ. Copper-induced cell death. Science (New York, NY). 2022;375(6586):1231\u20132. https:\/\/doi.org\/10.1126\/science.abo3959.","journal-title":"Science (New York, NY)"},{"issue":"1","key":"3375_CR15","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1038\/s41392-022-01229-y","volume":"7","author":"L Chen","year":"2022","unstructured":"Chen L, Min J, Wang F. Copper homeostasis and cuproptosis in health and disease. Signal Transduct Target Ther. 2022;7(1):378. https:\/\/doi.org\/10.1038\/s41392-022-01229-y.","journal-title":"Signal Transduct Target Ther"},{"issue":"9","key":"3375_CR16","doi-asserted-by":"publisher","first-page":"105046","DOI":"10.1016\/j.jbc.2023.105046","volume":"299","author":"MB Dreishpoon","year":"2023","unstructured":"Dreishpoon MB, Bick NR, Petrova B, Warui DM, Cameron A, Booker SJ, et al. FDX1 regulates cellular protein lipoylation through direct binding to LIAS. J Biol Chem. 2023;299(9):105046. https:\/\/doi.org\/10.1016\/j.jbc.2023.105046.","journal-title":"J Biol Chem"},{"issue":"2","key":"3375_CR17","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1038\/s41589-022-01159-4","volume":"19","author":"V Schulz","year":"2023","unstructured":"Schulz V, Basu S, Freibert SA, Webert H, Boss L, M\u00fchlenhoff U, et al. Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2. Nat Chem Biol. 2023;19(2):206\u201317. https:\/\/doi.org\/10.1038\/s41589-022-01159-4.","journal-title":"Nat Chem Biol"},{"issue":"6586","key":"3375_CR18","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1126\/science.abf0529","volume":"375","author":"P Tsvetkov","year":"2022","unstructured":"Tsvetkov P, Coy S, Petrova B, Dreishpoon M, Verma A, Abdusamad M, et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science (New York, NY). 2022;375(6586):1254\u201361. https:\/\/doi.org\/10.1126\/science.abf0529.","journal-title":"Science (New York, NY)"},{"issue":"10","key":"3375_CR19","doi-asserted-by":"publisher","first-page":"2512","DOI":"10.1128\/jb.00058-10","volume":"192","author":"S Chillappagari","year":"2010","unstructured":"Chillappagari S, Seubert A, Trip H, Kuipers OP, Marahiel MA, Miethke M. Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. J Bacteriol. 2010;192(10):2512\u201324. https:\/\/doi.org\/10.1128\/jb.00058-10.","journal-title":"J Bacteriol"},{"issue":"10","key":"3375_CR20","doi-asserted-by":"publisher","first-page":"e2216722120","DOI":"10.1073\/pnas.2216722120","volume":"120","author":"M Zulkifli","year":"2023","unstructured":"Zulkifli M, Spelbring AN, Zhang Y, Soma S, Chen S, Li L, et al. FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery. Proc Natl Acad Sci USA. 2023;120(10):e2216722120. https:\/\/doi.org\/10.1073\/pnas.2216722120.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3375_CR21","doi-asserted-by":"publisher","first-page":"122223","DOI":"10.1016\/j.lfs.2023.122223","volume":"334","author":"Z Tian","year":"2023","unstructured":"Tian Z, Jiang S, Zhou J, Zhang W. Copper homeostasis and cuproptosis in mitochondria. Life Sci. 2023;334:122223. https:\/\/doi.org\/10.1016\/j.lfs.2023.122223.","journal-title":"Life Sci"},{"key":"3375_CR22","doi-asserted-by":"publisher","first-page":"101019","DOI":"10.1016\/j.mam.2021.101019","volume":"87","author":"P Valero","year":"2022","unstructured":"Valero P, Fuentes G, Cornejo M, Vega S, Grismaldo A, Pardo F, et al. Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus. Mol Aspects Med. 2022;87:101019. https:\/\/doi.org\/10.1016\/j.mam.2021.101019.","journal-title":"Mol Aspects Med"},{"issue":"6","key":"3375_CR23","doi-asserted-by":"publisher","first-page":"2922","DOI":"10.1016\/j.clnu.2018.12.032","volume":"38","author":"P Li","year":"2019","unstructured":"Li P, Yin J, Zhu Y, Li S, Chen S, Sun T, et al. Association between plasma concentration of copper and gestational diabetes mellitus. Clinical nutrition (Edinburgh, Scotland). 2019;38(6):2922\u20137. https:\/\/doi.org\/10.1016\/j.clnu.2018.12.032.","journal-title":"Clinical nutrition (Edinburgh, Scotland)"},{"issue":"1","key":"3375_CR24","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1186\/s12884-020-03081-w","volume":"20","author":"JT Enebe","year":"2020","unstructured":"Enebe JT, Dim CC, Ugwu EO, Enebe NO, Meka IA, Obioha KC, et al. Serum antioxidant micronutrient levels in pre-eclamptic pregnant women in Enugu, south-East Nigeria: a comparative cross-sectional analytical study. BMC Pregnancy Childbirth. 2020;20(1):392. https:\/\/doi.org\/10.1186\/s12884-020-03081-w.","journal-title":"BMC Pregnancy Childbirth"},{"key":"3375_CR25","doi-asserted-by":"publisher","first-page":"106061","DOI":"10.1016\/j.envint.2020.106061","volume":"144","author":"R Wang","year":"2020","unstructured":"Wang R, Zhang L, Chen Y, Zhang S, Zhuang T, Wang L, et al. Elevated non-essential metals and the disordered metabolism of essential metals are associated to abnormal pregnancy with spontaneous abortion. Environ Int. 2020;144:106061. https:\/\/doi.org\/10.1016\/j.envint.2020.106061.","journal-title":"Environ Int"},{"key":"3375_CR26","doi-asserted-by":"publisher","unstructured":"Lewandowska M, Wi\u0119ckowska B, Sajdak S, Lubi\u0144ski J. First trimester microelements and their relationships with pregnancy outcomes and complications. Nutrients. 2020;12(4). https:\/\/doi.org\/10.3390\/nu12041108.","DOI":"10.3390\/nu12041108"},{"issue":"1","key":"3375_CR27","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1080\/15513815.2020.1857484","volume":"41","author":"\u00d6 Y\u00fccel \u00c7elik","year":"2022","unstructured":"Y\u00fccel \u00c7elik \u00d6, Akdas S, Yucel A, Kesikli B, Yazihan N, Uygur D. Maternal and placental zinc and copper status in intra-uterine growth restriction. Fetal Pediatr Pathol. 2022;41(1):107\u201315. https:\/\/doi.org\/10.1080\/15513815.2020.1857484.","journal-title":"Fetal Pediatr Pathol"},{"issue":"2","key":"3375_CR28","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1007\/s12016-020-08780-y","volume":"61","author":"CM Kang","year":"2021","unstructured":"Kang CM, Chiang BL, Wang LC. Maternal nutritional status and development of atopic dermatitis in their offspring. Clin Rev Allergy Immunol. 2021;61(2):128\u201355. https:\/\/doi.org\/10.1007\/s12016-020-08780-y.","journal-title":"Clin Rev Allergy Immunol"},{"issue":"5 Suppl 1","key":"3375_CR29","doi-asserted-by":"publisher","first-page":"1554s","DOI":"10.1093\/jn\/133.5.1554S","volume":"133","author":"L Gambling","year":"2003","unstructured":"Gambling L, Danzeisen R, Fosset C, Andersen HS, Dunford S, Srai SK, et al. Iron and copper interactions in development and the effect on pregnancy outcome. J Nutr. 2003;133(5 Suppl 1):1554s-s1556. https:\/\/doi.org\/10.1093\/jn\/133.5.1554S.","journal-title":"J Nutr"},{"issue":"5 Suppl","key":"3375_CR30","doi-asserted-by":"publisher","first-page":"1003s","DOI":"10.1093\/ajcn\/67.5.1003S","volume":"67","author":"CL Keen","year":"1998","unstructured":"Keen CL, Uriu-Hare JY, Hawk SN, Jankowski MA, Daston GP, Kwik-Uribe CL, et al. Effect of copper deficiency on prenatal development and pregnancy outcome. Am J Clin Nutr. 1998;67(5 Suppl):1003s-s1011. https:\/\/doi.org\/10.1093\/ajcn\/67.5.1003S.","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"3375_CR31","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s00439-006-0202-5","volume":"120","author":"P Ferenci","year":"2006","unstructured":"Ferenci P. Regional distribution of mutations of the ATP7B gene in patients with Wilson disease: impact on genetic testing. Hum Genet. 2006;120(2):151\u20139. https:\/\/doi.org\/10.1007\/s00439-006-0202-5.","journal-title":"Hum Genet"},{"issue":"1","key":"3375_CR32","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/s1474-4422(14)70190-5","volume":"14","author":"O Bandmann","year":"2015","unstructured":"Bandmann O, Weiss KH, Kaler SG. Wilson\u2019s disease and other neurological copper disorders. Lancet Neurol. 2015;14(1):103\u201313. https:\/\/doi.org\/10.1016\/s1474-4422(14)70190-5.","journal-title":"Lancet Neurol"},{"issue":"5","key":"3375_CR33","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/ejhg.2009.187","volume":"18","author":"Z T\u00fcmer","year":"2010","unstructured":"T\u00fcmer Z, M\u00f8ller LB. Menkes disease. Eur J Human Gen: EJHG. 2010;18(5):511\u20138. https:\/\/doi.org\/10.1038\/ejhg.2009.187.","journal-title":"Eur J Human Gen: EJHG"},{"key":"3375_CR34","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/978-1-4615-4859-1_7","volume":"448","author":"Z T\u00fcmer","year":"1999","unstructured":"T\u00fcmer Z, M\u00f8ller LB, Horn N. Mutation spectrum of ATP7A, the gene defective in Menkes disease. Adv Exp Med Biol. 1999;448:83\u201395. https:\/\/doi.org\/10.1007\/978-1-4615-4859-1_7.","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"3375_CR35","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1152\/physrev.1987.67.3.858","volume":"67","author":"JR Prohaska","year":"1987","unstructured":"Prohaska JR. Functions of trace elements in brain metabolism. Physiol Rev. 1987;67(3):858\u2013901. https:\/\/doi.org\/10.1152\/physrev.1987.67.3.858.","journal-title":"Physiol Rev"},{"issue":"4","key":"3375_CR36","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1159\/000299148","volume":"17","author":"P Kiilholma","year":"1984","unstructured":"Kiilholma P, Gr\u00f6nroos M, Erkkola R, Pakarinen P, N\u00e4nt\u00f6 V. The role of calcium, copper, iron and zinc in preterm delivery and premature rupture of fetal membranes. Gynecol Obstet Invest. 1984;17(4):194\u2013201. https:\/\/doi.org\/10.1159\/000299148.","journal-title":"Gynecol Obstet Invest"},{"issue":"2","key":"3375_CR37","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s12291-013-0338-8","volume":"29","author":"M Jariwala","year":"2014","unstructured":"Jariwala M, Suvarna S, Kiran Kumar G, Amin A, Udas AC. Study of the concentration of trace elements Fe, Zn, Cu, Se and their correlation in maternal serum, cord serum and colostrums. Indian J Clin Biochem: IJCB. 2014;29(2):181\u20138. https:\/\/doi.org\/10.1007\/s12291-013-0338-8.","journal-title":"Indian J Clin Biochem: IJCB"},{"key":"3375_CR38","doi-asserted-by":"publisher","unstructured":"Minoia C, Sabbioni E, Apostoli P, Pietra R, Pozzoli L, Gallorini M, et al. Trace element reference values in tissues from inhabitants of the European community. I. A study of 46 elements in urine, blood and serum of Italian subjects. Sci Total Environ. 1990;95:89\u2013105. https:\/\/doi.org\/10.1016\/0048-9697(90)90055-y.","DOI":"10.1016\/0048-9697(90)90055-y"},{"key":"3375_CR39","doi-asserted-by":"crossref","unstructured":"Caroli S, Alimonti A, Coni E, Petrucci F, Senofonte O, Violante NJCRiAC. The assessment of reference values for elements in human biological tissues and fluids: a systematic review. 1994;24:363-98","DOI":"10.1080\/10408349408048824"},{"issue":"2","key":"3375_CR40","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1007\/s12291-013-0336-x","volume":"29","author":"FM Tabrizi","year":"2014","unstructured":"Tabrizi FM, Pakdel FG. Serum level of some minerals during three trimesters of pregnancy in Iranian women and their newborns: a longitudinal study. Indian J Clin Biochem: IJCB. 2014;29(2):174\u201380. https:\/\/doi.org\/10.1007\/s12291-013-0336-x.","journal-title":"Indian J Clin Biochem: IJCB"},{"issue":"1","key":"3375_CR41","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1186\/s12884-023-05625-2","volume":"23","author":"H Gohari","year":"2023","unstructured":"Gohari H, Khajavian N, Mahmoudian A, Bilandi RR. Copper and zinc deficiency to the risk of preterm labor in pregnant women: a case-control study. BMC Pregnancy Childbirth. 2023;23(1):366. https:\/\/doi.org\/10.1186\/s12884-023-05625-2.","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"3375_CR42","doi-asserted-by":"publisher","first-page":"97","DOI":"10.22074\/ijfs.2019.5586","volume":"13","author":"R Thaker","year":"2019","unstructured":"Thaker R, Oza H, Shaikh I, Kumar S. Correlation of copper and zinc in spontaneous abortion. Intl J Fertil Steril. 2019;13(2):97\u2013101. https:\/\/doi.org\/10.22074\/ijfs.2019.5586.","journal-title":"Intl J Fertil Steril"},{"key":"3375_CR43","doi-asserted-by":"publisher","unstructured":"Lewandowska M, Sajdak S, Marciniak W, Lubi\u0144ski J. First trimester serum copper or zinc levels, and risk of pregnancy-induced hypertension. Nutrients. 2019;11(10). https:\/\/doi.org\/10.3390\/nu11102479.","DOI":"10.3390\/nu11102479"},{"issue":"12","key":"3375_CR44","doi-asserted-by":"publisher","first-page":"4396","DOI":"10.1007\/s12011-020-02566-1","volume":"199","author":"S Lian","year":"2021","unstructured":"Lian S, Zhang T, Yu Y, Zhang B. Relationship of circulating copper level with gestational diabetes mellitus: a meta-analysis and systemic review. Biol Trace Elem Res. 2021;199(12):4396\u2013409. https:\/\/doi.org\/10.1007\/s12011-020-02566-1.","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"3375_CR45","first-page":"157","volume":"28","author":"FA Mishu","year":"2019","unstructured":"Mishu FA, Boral N, Ferdous N, Nahar S, Sultana GS, Yesmin MS, et al. Estimation of serum zinc, copper and magnesium levels in Bangladeshi women with Gestational diabetes mellitus attending in a tertiary care hospital. Mymensingh Med J: MMJ. 2019;28(1):157\u201362.","journal-title":"Mymensingh Med J: MMJ"},{"key":"3375_CR46","doi-asserted-by":"crossref","unstructured":"Ugwuja E, Ejikeme BN, Ugwu NC, Obeka NC, Akubugwo EI, Obidoa OJPJoN. Comparison of plasma copper, iron and zinc levels in hypertensive and non-hypertensive pregnant women in Abakaliki, South Eastern Nigeria. 2010;9:1136-40","DOI":"10.3923\/pjn.2010.1136.1140"},{"issue":"2","key":"3375_CR47","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/0028-2243(79)90003-0","volume":"9","author":"BA Bassiouni","year":"1979","unstructured":"Bassiouni BA, Rafei AA. 5-Hydroxytryptamine (serotonin), copper and ceruloplasmin plasma concentrations in spontaneous abortion. Eur J Obstet Gynecol Reprod Biol. 1979;9(2):81\u20138. https:\/\/doi.org\/10.1016\/0028-2243(79)90003-0.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"3375_CR48","doi-asserted-by":"publisher","unstructured":"Cornelis R, Fuentes-Arderiu X, Bruunshuus I, Templeton D. Properties and units in the clinical laboratory sciences. IX. Properties and units in trace elements (IUPAC-IFCC Technical report 1997). International Union of Pure and Applied Chemistry and International Federation of Clinical Chemistry. rita.cornelis@rug.ac.be. Clinica chimica acta; international journal of clinical chemistry. 1997;268(1\u20132):S75\u201389. https:\/\/doi.org\/10.1016\/s0009-8981(97)00146-0.","DOI":"10.1016\/s0009-8981(97)00146-0"},{"issue":"12","key":"3375_CR49","doi-asserted-by":"publisher","first-page":"6836","DOI":"10.1073\/pnas.111057298","volume":"98","author":"YM Kuo","year":"2001","unstructured":"Kuo YM, Zhou B, Cosco D, Gitschier J. The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc Natl Acad Sci USA. 2001;98(12):6836\u201341. https:\/\/doi.org\/10.1073\/pnas.111057298.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"12","key":"3375_CR50","doi-asserted-by":"publisher","first-page":"6842","DOI":"10.1073\/pnas.111058698","volume":"98","author":"J Lee","year":"2001","unstructured":"Lee J, Prohaska JR, Thiele DJ. Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci USA. 2001;98(12):6842\u20137. https:\/\/doi.org\/10.1073\/pnas.111058698.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"3375_CR51","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1074\/mcp.M113.035600","volume":"13","author":"L Fagerberg","year":"2014","unstructured":"Fagerberg L, Hallstr\u00f6m BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteom: MCP. 2014;13(2):397\u2013406. https:\/\/doi.org\/10.1074\/mcp.M113.035600.","journal-title":"Mol Cell Proteom: MCP"},{"issue":"1","key":"3375_CR52","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1186\/s12967-023-04533-5","volume":"21","author":"M Tarin","year":"2023","unstructured":"Tarin M, Babaie M, Eshghi H, Matin MM, Saljooghi AS. Elesclomol, a copper-transporting therapeutic agent targeting mitochondria: from discovery to its novel applications. J Transl Med. 2023;21(1):745. https:\/\/doi.org\/10.1186\/s12967-023-04533-5.","journal-title":"J Transl Med"},{"issue":"6641","key":"3375_CR53","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/41343","volume":"388","author":"H Gunshin","year":"1997","unstructured":"Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature. 1997;388(6641):482\u20138. https:\/\/doi.org\/10.1038\/41343.","journal-title":"Nature"},{"issue":"2","key":"3375_CR54","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1074\/jbc.R800055200","volume":"284","author":"ML Turski","year":"2009","unstructured":"Turski ML, Thiele DJ. New roles for copper metabolism in cell proliferation, signaling, and disease. J Biol Chem. 2009;284(2):717\u201321. https:\/\/doi.org\/10.1074\/jbc.R800055200.","journal-title":"J Biol Chem"},{"issue":"52","key":"3375_CR55","doi-asserted-by":"publisher","first-page":"20085","DOI":"10.1074\/jbc.RA118.004889","volume":"293","author":"K Schmidt","year":"2018","unstructured":"Schmidt K, Ralle M, Schaffer T, Jayakanthan S, Bari B, Muchenditsi A, et al. ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine-\u03b2-hydroxylase. J Biol Chem. 2018;293(52):20085\u201398. https:\/\/doi.org\/10.1074\/jbc.RA118.004889.","journal-title":"J Biol Chem"},{"issue":"1","key":"3375_CR56","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/nrneurol.2010.180","volume":"7","author":"SG Kaler","year":"2011","unstructured":"Kaler SG. ATP7A-related copper transport diseases-emerging concepts and future trends. Nat Rev Neurol. 2011;7(1):15\u201329. https:\/\/doi.org\/10.1038\/nrneurol.2010.180.","journal-title":"Nat Rev Neurol"},{"issue":"10","key":"3375_CR57","doi-asserted-by":"publisher","first-page":"9640","DOI":"10.1074\/jbc.M413840200","volume":"280","author":"N Barnes","year":"2005","unstructured":"Barnes N, Tsivkovskii R, Tsivkovskaia N, Lutsenko S. The copper-transporting ATPases, menkes and Wilson disease proteins, have distinct roles in adult and developing cerebellum. J Biol Chem. 2005;280(10):9640\u20135. https:\/\/doi.org\/10.1074\/jbc.M413840200.","journal-title":"J Biol Chem"},{"issue":"3","key":"3375_CR58","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1152\/physrev.00004.2006","volume":"87","author":"S Lutsenko","year":"2007","unstructured":"Lutsenko S, Barnes NL, Bartee MY, Dmitriev OY. Function and regulation of human copper-transporting ATPases. Physiol Rev. 2007;87(3):1011\u201346. https:\/\/doi.org\/10.1152\/physrev.00004.2006.","journal-title":"Physiol Rev"},{"issue":"31","key":"3375_CR59","doi-asserted-by":"publisher","first-page":"22008","DOI":"10.1074\/jbc.274.31.22008","volume":"274","author":"I Voskoboinik","year":"1999","unstructured":"Voskoboinik I, Strausak D, Greenough M, Brooks H, Petris M, Smith S, et al. Functional analysis of the N-terminal CXXC metal-binding motifs in the human Menkes copper-transporting P-type ATPase expressed in cultured mammalian cells. J Biol Chem. 1999;274(31):22008\u201312. https:\/\/doi.org\/10.1074\/jbc.274.31.22008.","journal-title":"J Biol Chem"},{"issue":"3","key":"3375_CR60","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00418-013-1123-8","volume":"140","author":"R Polishchuk","year":"2013","unstructured":"Polishchuk R, Lutsenko S. Golgi in copper homeostasis: a view from the membrane trafficking field. Histochem Cell Biol. 2013;140(3):285\u201395. https:\/\/doi.org\/10.1007\/s00418-013-1123-8.","journal-title":"Histochem Cell Biol"},{"issue":"Pt 3","key":"3375_CR61","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1042\/bj20031804","volume":"380","author":"MA Cater","year":"2004","unstructured":"Cater MA, Forbes J, La Fontaine S, Cox D, Mercer JF. Intracellular trafficking of the human Wilson protein: the role of the six N-terminal metal-binding sites. Biochem J. 2004;380(Pt 3):805\u201313. https:\/\/doi.org\/10.1042\/bj20031804.","journal-title":"Biochem J"},{"issue":"16","key":"3375_CR62","doi-asserted-by":"publisher","first-page":"11170","DOI":"10.1074\/jbc.274.16.11170","volume":"274","author":"D Strausak","year":"1999","unstructured":"Strausak D, La Fontaine S, Hill J, Firth SD, Lockhart PJ, Mercer JF. The role of GMXCXXC metal binding sites in the copper-induced redistribution of the Menkes protein. J Biol Chem. 1999;274(16):11170\u20137. https:\/\/doi.org\/10.1074\/jbc.274.16.11170.","journal-title":"J Biol Chem"},{"key":"3375_CR63","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1016\/b978-0-444-59565-2.00045-9","volume":"113","author":"SG Kaler","year":"2013","unstructured":"Kaler SG. Inborn errors of copper metabolism. Handb Clin Neurol. 2013;113:1745\u201354. https:\/\/doi.org\/10.1016\/b978-0-444-59565-2.00045-9.","journal-title":"Handb Clin Neurol"},{"key":"3375_CR64","doi-asserted-by":"publisher","unstructured":"Robison ATR, Sturrock GR, Zaengle-Barone JM, Wiebelhaus N, Dharani A, Williams IG, et al. Analysis of copper-induced protein precipitation across the E. coli proteome. Metallomics: Integr Biometal Sci. 2023;15(1). https:\/\/doi.org\/10.1093\/mtomcs\/mfac098.","DOI":"10.1093\/mtomcs\/mfac098"},{"issue":"7","key":"3375_CR65","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1038\/s41589-019-0291-9","volume":"15","author":"P Tsvetkov","year":"2019","unstructured":"Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, et al. Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nat Chem Biol. 2019;15(7):681\u20139. https:\/\/doi.org\/10.1038\/s41589-019-0291-9.","journal-title":"Nat Chem Biol"},{"issue":"5","key":"3375_CR66","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060\u201372. https:\/\/doi.org\/10.1016\/j.cell.2012.03.042.","journal-title":"Cell"},{"key":"3375_CR67","doi-asserted-by":"publisher","unstructured":"Carpenter KL, Wilkins GM, Fussell B, Ballantine JA, Taylor SE, Mitchinson MJ, et al. Production of oxidized lipids during modification of low-density lipoprotein by macrophages or copper. Biochem J. 1994;304 ( Pt 2)(Pt 2):625\u201333. https:\/\/doi.org\/10.1042\/bj3040625.","DOI":"10.1042\/bj3040625"},{"issue":"2","key":"3375_CR68","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.abb.2007.07.005","volume":"465","author":"ET Horsley","year":"2007","unstructured":"Horsley ET, Burkitt MJ, Jones CM, Patterson RA, Harris LK, Moss NJ, et al. Mechanism of the antioxidant to pro-oxidant switch in the behavior of dehydroascorbate during LDL oxidation by copper(II) ions. Arch Biochem Biophys. 2007;465(2):303\u201314. https:\/\/doi.org\/10.1016\/j.abb.2007.07.005.","journal-title":"Arch Biochem Biophys"},{"key":"3375_CR69","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.jinorgbio.2016.10.009","volume":"166","author":"C Saporito-Magri\u00f1\u00e1","year":"2017","unstructured":"Saporito-Magri\u00f1\u00e1 C, Musacco-Sebio R, Acosta JM, Bajicoff S, Paredes-Fleitas P, Boveris A, et al. Rat liver mitochondrial dysfunction by addition of copper(II) or iron(III) ions. J Inorg Biochem. 2017;166:5\u201311. https:\/\/doi.org\/10.1016\/j.jinorgbio.2016.10.009.","journal-title":"J Inorg Biochem"},{"key":"3375_CR70","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.biocel.2018.07.001","volume":"102","author":"H Zischka","year":"2018","unstructured":"Zischka H, Einer C. Mitochondrial copper homeostasis and its derailment in Wilson disease. Int J Biochem Cell Biol. 2018;102:71\u20135. https:\/\/doi.org\/10.1016\/j.biocel.2018.07.001.","journal-title":"Int J Biochem Cell Biol"},{"issue":"2","key":"3375_CR71","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.molcel.2018.10.042","volume":"73","author":"M Gao","year":"2019","unstructured":"Gao M, Yi J, Zhu J, Minikes AM, Monian P, Thompson CB, et al. Role of mitochondria in ferroptosis. Mol Cell. 2019;73(2):354-63.e3. https:\/\/doi.org\/10.1016\/j.molcel.2018.10.042.","journal-title":"Mol Cell"},{"issue":"3","key":"3375_CR72","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1080\/15592294.2019.1661211","volume":"15","author":"E Kennedy","year":"2020","unstructured":"Kennedy E, Everson TM, Punshon T, Jackson BP, Hao K, Lambertini L, et al. Copper associates with differential methylation in placentae from two US birth cohorts. Epigenetics. 2020;15(3):215\u201330. https:\/\/doi.org\/10.1080\/15592294.2019.1661211.","journal-title":"Epigenetics"},{"key":"3375_CR73","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/978-3-642-00663-0_6","volume":"196","author":"PG Wells","year":"2010","unstructured":"Wells PG, Lee CJ, McCallum GP, Perstin J, Harper PA. Receptor- and reactive intermediate-mediated mechanisms of teratogenesis. Handb Exp Pharmacol. 2010;196:131\u201362. https:\/\/doi.org\/10.1007\/978-3-642-00663-0_6.","journal-title":"Handb Exp Pharmacol"},{"issue":"1","key":"3375_CR74","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1186\/s12940-022-00950-z","volume":"21","author":"T Michael","year":"2022","unstructured":"Michael T, Kohn E, Daniel S, Hazan A, Berkovitch M, Brik A, et al. Prenatal exposure to heavy metal mixtures and anthropometric birth outcomes: a cross-sectional study. Environ Health: a Global Access Sci Source. 2022;21(1):139. https:\/\/doi.org\/10.1186\/s12940-022-00950-z.","journal-title":"Environ Health: a Global Access Sci Source"},{"issue":"2","key":"3375_CR75","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jtemb.2009.02.005","volume":"23","author":"M Zadrozna","year":"2009","unstructured":"Zadrozna M, Gawlik M, Nowak B, Marcinek A, Mrowiec H, Walas S, et al. Antioxidants activities and concentration of selenium, zinc and copper in preterm and IUGR human placentas. J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS). 2009;23(2):144\u20138. https:\/\/doi.org\/10.1016\/j.jtemb.2009.02.005.","journal-title":"J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)"},{"key":"3375_CR76","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.placenta.2021.05.001","volume":"110","author":"MD G\u00f3mez-Roig","year":"2021","unstructured":"G\u00f3mez-Roig MD, Mazarico E, Cuadras D, Muniesa M, Pascal R, Ferrer P, et al. Placental chemical elements concentration in small fetuses and its relationship with Doppler markers of placental function. Placenta. 2021;110:1\u20138. https:\/\/doi.org\/10.1016\/j.placenta.2021.05.001.","journal-title":"Placenta"},{"key":"3375_CR77","doi-asserted-by":"publisher","first-page":"5062365","DOI":"10.1155\/2019\/5062365","volume":"2019","author":"R Irwinda","year":"2019","unstructured":"Irwinda R, Wibowo N, Putri AS. The concentration of micronutrients and heavy metals in maternal serum, placenta, and cord blood: a cross-sectional study in preterm birth. J Pregnancy. 2019;2019:5062365. https:\/\/doi.org\/10.1155\/2019\/5062365.","journal-title":"J Pregnancy"},{"issue":"3","key":"3375_CR78","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1002\/jat.1490","volume":"30","author":"S Stasenko","year":"2010","unstructured":"Stasenko S, Bradford EM, Piasek M, Henson MC, Varnai VM, Jurasovi\u0107 J, et al. Metals in human placenta: focus on the effects of cadmium on steroid hormones and leptin. J Appl Toxicol: JAT. 2010;30(3):242\u201353. https:\/\/doi.org\/10.1002\/jat.1490.","journal-title":"J Appl Toxicol: JAT"},{"key":"3375_CR79","unstructured":"Hart EB, Steenbock H, Waddell J, Elvehjem CA. Iron in nutrition. VII. Copper as a supplement to iron for hemoglobin building in the rat. 1928. J Biol Chem. 2002;277(34):e22."},{"key":"3375_CR80","doi-asserted-by":"crossref","unstructured":"Keil HL, Nelson VEJJoBC. The role of copper in h\u00e6moglobin regeneration and in reproduction. 1931;93:49-57","DOI":"10.1016\/S0021-9258(18)76487-9"},{"key":"3375_CR81","doi-asserted-by":"crossref","unstructured":"Bennetts HW, Chapman FEJAVJ. Copper deficiency in sheep in Western Australia: a preliminary account of the \u00e6tiology of enzootic ataxia of lambs and an an\u00e6mia of ewes. 1937;13:138-49","DOI":"10.1111\/j.1751-0813.1937.tb04108.x"},{"issue":"12","key":"3375_CR82","doi-asserted-by":"publisher","first-page":"2424","DOI":"10.1093\/jn\/116.12.2424","volume":"116","author":"GD Mieden","year":"1986","unstructured":"Mieden GD, Keen CL, Hurley LS, Klein NW. Effects of whole rat embryos cultured on serum from zinc- and copper-deficient rats. J Nutr. 1986;116(12):2424\u201331. https:\/\/doi.org\/10.1093\/jn\/116.12.2424.","journal-title":"J Nutr"},{"key":"3375_CR83","doi-asserted-by":"publisher","unstructured":"Hawk SN, Uriu-Hare JY, Daston GP, Jankowski MA, Kwik-Uribe C, Rucker RB, et al. Rat embryos cultured under copper-deficient conditions develop abnormally and are characterized by an impaired oxidant defense system. Teratology. 1998;57(6):310\u201320. https:\/\/doi.org\/10.1002\/(sici)1096-9926(199806)57:6%3c310::Aid-tera4%3e3.0.Co;2-#.","DOI":"10.1002\/(sici)1096-9926(199806)57:6%3c310::Aid-tera4%3e3.0.Co;2-#"},{"issue":"3","key":"3375_CR84","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1002\/cbf.1235","volume":"24","author":"Z Serdar","year":"2006","unstructured":"Serdar Z, G\u00fcr E, Develio\u011flu O. Serum iron and copper status and oxidative stress in severe and mild preeclampsia. Cell Biochem Funct. 2006;24(3):209\u201315. https:\/\/doi.org\/10.1002\/cbf.1235.","journal-title":"Cell Biochem Funct"},{"issue":"1\u20132","key":"3375_CR85","doi-asserted-by":"publisher","first-page":"42","DOI":"10.2298\/SARH1202042V","volume":"140","author":"J Vukeli\u0107","year":"2012","unstructured":"Vukeli\u0107 J, Kapamadzija A, Petrovi\u0107 D, Gruji\u0107 Z, Novakov-Miki\u0107 A, Kopitovi\u0107 V, et al. Variations of serum copper values in pregnancy. Srp Arh Celok Lek. 2012;140(1\u20132):42\u20136.","journal-title":"Srp Arh Celok Lek"},{"issue":"11","key":"3375_CR86","doi-asserted-by":"publisher","first-page":"2382","DOI":"10.1093\/ajcn\/34.11.2382","volume":"34","author":"SC Vir","year":"1981","unstructured":"Vir SC, Love AH, Thompson W. Serum and hair concentrations of copper during pregnancy. Am J Clin Nutr. 1981;34(11):2382\u20138. https:\/\/doi.org\/10.1093\/ajcn\/34.11.2382.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"3375_CR87","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s43054-021-00059-x","volume":"69","author":"M Abdellatif","year":"2021","unstructured":"Abdellatif M, Elhawary IM, Mahmoud MM, Youness ER, Abuelhamd WA. Cord levels of zinc and copper in relation to maternal serum levels in different gestational ages. Egypt Pediatr Assoc Gazette. 2021;69(1):11. https:\/\/doi.org\/10.1186\/s43054-021-00059-x.","journal-title":"Egypt Pediatr Assoc Gazette"},{"issue":"11","key":"3375_CR88","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.earlhumdev.2015.08.013","volume":"91","author":"NJ Andreas","year":"2015","unstructured":"Andreas NJ, Kampmann B, Mehring L-D. Human breast milk: a review on its composition and bioactivity. Early Human Dev. 2015;91(11):629\u201335. https:\/\/doi.org\/10.1016\/j.earlhumdev.2015.08.013.","journal-title":"Early Human Dev"},{"issue":"11\u201312","key":"3375_CR89","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/s0899-9007(00)00426-3","volume":"16","author":"FM Al-Awadi","year":"2000","unstructured":"Al-Awadi FM, Srikumar TS. Trace-element status in milk and plasma of Kuwaiti and non-Kuwaiti lactating mothers. Nutrition (Burbank, Los Angeles County, Calif). 2000;16(11\u201312):1069\u201373. https:\/\/doi.org\/10.1016\/s0899-9007(00)00426-3.","journal-title":"Nutrition (Burbank, Los Angeles County, Calif)"},{"issue":"4","key":"3375_CR90","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/s0946-672x(99)80062-5","volume":"12","author":"ML Dodge","year":"1999","unstructured":"Dodge ML, Wander RC, Xia Y, Butler JA, Whanger PD. Glutathione peroxidase activity modulates fatty acid profiles of plasma and breast milk in Chinese women. J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS). 1999;12(4):221\u201330. https:\/\/doi.org\/10.1016\/s0946-672x(99)80062-5.","journal-title":"J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)"},{"issue":"1","key":"3375_CR91","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1007\/s12011-013-9870-x","volume":"157","author":"A Winiarska-Mieczan","year":"2014","unstructured":"Winiarska-Mieczan A. Cadmium, lead, copper and zinc in breast milk in Poland. Biol Trace Elem Res. 2014;157(1):36\u201344. https:\/\/doi.org\/10.1007\/s12011-013-9870-x.","journal-title":"Biol Trace Elem Res"},{"issue":"1\u20132","key":"3375_CR92","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/s0300-483x(03)00159-8","volume":"189","author":"LM Gaetke","year":"2003","unstructured":"Gaetke LM, Chow CK. Copper toxicity, oxidative stress, and antioxidant nutrients. Toxicology. 2003;189(1\u20132):147\u201363. https:\/\/doi.org\/10.1016\/s0300-483x(03)00159-8.","journal-title":"Toxicology"},{"key":"3375_CR93","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.jtemb.2018.09.008","volume":"51","author":"PC Castillo-Casta\u00f1eda","year":"2019","unstructured":"Castillo-Casta\u00f1eda PC, Garc\u00eda-Gonz\u00e1lez A, Bencomo-Alvarez AE, Barros-Nu\u00f1ez P, Gaxiola-Robles R, M\u00e9ndez-Rodr\u00edguez LC, et al. Micronutrient content and antioxidant enzyme activities in human breast milk. J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS). 2019;51:36\u201341. https:\/\/doi.org\/10.1016\/j.jtemb.2018.09.008.","journal-title":"J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)"},{"issue":"2","key":"3375_CR94","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/tera.1420510207","volume":"51","author":"MA Jankowski","year":"1995","unstructured":"Jankowski MA, Uriu-Hare JY, Rucker RB, Rogers JM, Keen CL. Maternal zinc deficiency, but not copper deficiency or diabetes, results in increased embryonic cell death in the rat: implications for mechanisms underlying abnormal development. Teratology. 1995;51(2):85\u201393. https:\/\/doi.org\/10.1002\/tera.1420510207.","journal-title":"Teratology"},{"key":"3375_CR95","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.theriogenology.2017.04.037","volume":"97","author":"JP Anchordoquy","year":"2017","unstructured":"Anchordoquy JP, Anchordoquy JM, Pascua AM, Nikoloff N, Peral-Garc\u00eda P, Furnus CC. The copper transporter (SLC31A1\/CTR1) is expressed in bovine spermatozoa and oocytes: copper in IVF medium improves sperm quality. Theriogenology. 2017;97:124\u201333. https:\/\/doi.org\/10.1016\/j.theriogenology.2017.04.037.","journal-title":"Theriogenology"},{"issue":"3","key":"3375_CR96","doi-asserted-by":"publisher","first-page":"168","DOI":"10.5001\/omj.2010.51","volume":"25","author":"OF Abdul-Rasheed","year":"2010","unstructured":"Abdul-Rasheed OF. Association between seminal plasma copper and magnesium levels with oxidative stress in Iraqi infertile men. Oman Med J. 2010;25(3):168\u201372. https:\/\/doi.org\/10.5001\/omj.2010.51.","journal-title":"Oman Med J"},{"issue":"8","key":"3375_CR97","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1007\/s10646-014-1295-6","volume":"23","author":"A Miska-Schramm","year":"2014","unstructured":"Miska-Schramm A, Kruczek M, Kapusta J. Effect of copper exposure on reproductive ability in the bank vole (Myodes glareolus). Ecotoxicology (London, England). 2014;23(8):1546\u201354. https:\/\/doi.org\/10.1007\/s10646-014-1295-6.","journal-title":"Ecotoxicology (London, England)"},{"issue":"2","key":"3375_CR98","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1152\/physrev.1985.65.2.238","volume":"65","author":"RJ Cousins","year":"1985","unstructured":"Cousins RJ. Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev. 1985;65(2):238\u2013309. https:\/\/doi.org\/10.1152\/physrev.1985.65.2.238.","journal-title":"Physiol Rev"},{"key":"3375_CR99","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3389\/fnagi.2014.00173","volume":"6","author":"DB Lovejoy","year":"2014","unstructured":"Lovejoy DB, Guillemin GJ. The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis. Front Aging Neurosc. 2014;6:173. https:\/\/doi.org\/10.3389\/fnagi.2014.00173.","journal-title":"Front Aging Neurosc"},{"issue":"5","key":"3375_CR100","doi-asserted-by":"publisher","first-page":"8004","DOI":"10.3390\/ijms15058004","volume":"15","author":"A Le","year":"2014","unstructured":"Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, et al. Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease. Int J Mol Sci. 2014;15(5):8004\u201323. https:\/\/doi.org\/10.3390\/ijms15058004.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"3375_CR101","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/hep.26047","volume":"57","author":"V Medici","year":"2013","unstructured":"Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, et al. Wilson\u2019s disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatology (Baltimore, MD). 2013;57(2):555\u201365. https:\/\/doi.org\/10.1002\/hep.26047.","journal-title":"Hepatology (Baltimore, MD)"},{"issue":"12","key":"3375_CR102","doi-asserted-by":"publisher","first-page":"2478","DOI":"10.1038\/nprot.2017.124","volume":"12","author":"J Ernst","year":"2017","unstructured":"Ernst J, Kellis M. Chromatin-state discovery and genome annotation with ChromHMM. Nat Protoc. 2017;12(12):2478\u201392. https:\/\/doi.org\/10.1038\/nprot.2017.124.","journal-title":"Nat Protoc"},{"issue":"7539","key":"3375_CR103","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/nature14248","volume":"518","author":"A Kundaje","year":"2015","unstructured":"Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al. Integrative analysis of 111 reference human epigenomes. Nature. 2015;518(7539):317\u201330. https:\/\/doi.org\/10.1038\/nature14248.","journal-title":"Nature"},{"issue":"2","key":"3375_CR104","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.placenta.2012.12.001","volume":"34","author":"EJ Crosley","year":"2013","unstructured":"Crosley EJ, Elliot MG, Christians JK, Crespi BJ. Placental invasion, preeclampsia risk and adaptive molecular evolution at the origin of the great apes: evidence from genome-wide analyses. Placenta. 2013;34(2):127\u201332. https:\/\/doi.org\/10.1016\/j.placenta.2012.12.001.","journal-title":"Placenta"},{"issue":"6","key":"3375_CR105","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/s0029-7844(99)00433-0","volume":"94","author":"PL Zusterzeel","year":"1999","unstructured":"Zusterzeel PL, Peters WH, De Bruyn MA, Knapen MF, Merkus HM, Steegers EA. Glutathione S-transferase isoenzymes in decidua and placenta of preeclamptic pregnancies. Obstet Gynecol. 1999;94(6):1033\u20138. https:\/\/doi.org\/10.1016\/s0029-7844(99)00433-0.","journal-title":"Obstet Gynecol"},{"issue":"6","key":"3375_CR106","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1007\/s00125-011-2109-5","volume":"54","author":"TL Hectors","year":"2011","unstructured":"Hectors TL, Vanparys C, van der Ven K, Martens GA, Jorens PG, Van Gaal LF, et al. Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function. Diabetologia. 2011;54(6):1273\u201390. https:\/\/doi.org\/10.1007\/s00125-011-2109-5.","journal-title":"Diabetologia"},{"issue":"1","key":"3375_CR107","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1002\/jat.3381","volume":"37","author":"L Schumacher","year":"2017","unstructured":"Schumacher L, Abbott LC. Effects of methyl mercury exposure on pancreatic beta cell development and function. J Appl Toxicol: JAT. 2017;37(1):4\u201312. https:\/\/doi.org\/10.1002\/jat.3381.","journal-title":"J Appl Toxicol: JAT"},{"key":"3375_CR108","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.toxlet.2018.09.015","volume":"299","author":"EN Dover","year":"2018","unstructured":"Dover EN, Patel NY, St\u00fdblo M. Impact of in vitro heavy metal exposure on pancreatic \u03b2-cell function. Toxicol Lett. 2018;299:137\u201344. https:\/\/doi.org\/10.1016\/j.toxlet.2018.09.015.","journal-title":"Toxicol Lett"},{"issue":"4","key":"3375_CR109","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1007\/s12011-020-02499-9","volume":"199","author":"T Onat","year":"2021","unstructured":"Onat T, Demir Caltekin M, Turksoy VA, Baser E, Aydogan Kirmizi D, Kara M, et al. The relationship between heavy metal exposure, trace element level, and monocyte to HDL cholesterol ratio with gestational diabetes mellitus. Biol Trace Elem Res. 2021;199(4):1306\u201315. https:\/\/doi.org\/10.1007\/s12011-020-02499-9.","journal-title":"Biol Trace Elem Res"},{"issue":"10","key":"3375_CR110","doi-asserted-by":"publisher","first-page":"4295","DOI":"10.1210\/jc.2019-00109","volume":"104","author":"Y Zheng","year":"2019","unstructured":"Zheng Y, Zhang C, Weisskopf M, Williams PL, Parsons PJ, Palmer CD, et al. A prospective study of early pregnancy essential metal(loid)s and glucose levels late in the second trimester. J Clin Endocrinol Metab. 2019;104(10):4295\u2013303. https:\/\/doi.org\/10.1210\/jc.2019-00109.","journal-title":"J Clin Endocrinol Metab"},{"key":"3375_CR111","doi-asserted-by":"publisher","first-page":"111854","DOI":"10.1016\/j.ecoenv.2020.111854","volume":"210","author":"Z Zhou","year":"2021","unstructured":"Zhou Z, Chen G, Li P, Rao J, Wang L, Yu D, et al. Prospective association of metal levels with gestational diabetes mellitus and glucose: a retrospective cohort study from South China. Ecotoxicol Environ Saf. 2021;210:111854. https:\/\/doi.org\/10.1016\/j.ecoenv.2020.111854.","journal-title":"Ecotoxicol Environ Saf"},{"issue":"11","key":"3375_CR112","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1007\/s00204-014-1355-y","volume":"88","author":"LM Gaetke","year":"2014","unstructured":"Gaetke LM, Chow-Johnson HS, Chow CK. Copper: toxicological relevance and mechanisms. Arch Toxicol. 2014;88(11):1929\u201338. https:\/\/doi.org\/10.1007\/s00204-014-1355-y.","journal-title":"Arch Toxicol"},{"key":"3375_CR113","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.freeradbiomed.2014.10.580","volume":"78","author":"HD Mistry","year":"2015","unstructured":"Mistry HD, Gill CA, Kurlak LO, Seed PT, Hesketh JE, M\u00e9plan C, et al. Association between maternal micronutrient status, oxidative stress, and common genetic variants in antioxidant enzymes at 15 weeks\u05f3 gestation in nulliparous women who subsequently develop preeclampsia. Free Radical Biol Med. 2015;78:147\u201355. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2014.10.580.","journal-title":"Free Radical Biol Med"},{"key":"3375_CR114","doi-asserted-by":"publisher","first-page":"83","DOI":"10.2174\/1874091x01408010083","volume":"8","author":"A Rafeeinia","year":"2014","unstructured":"Rafeeinia A, Tabandeh A, Khajeniazi S, Marjani AJ. Serum copper, zinc and lipid peroxidation in pregnant women with preeclampsia in Gorgan. Open Biochem J. 2014;8:83\u20138. https:\/\/doi.org\/10.2174\/1874091x01408010083.","journal-title":"Open Biochem J"},{"key":"3375_CR115","doi-asserted-by":"publisher","first-page":"841749","DOI":"10.1155\/2011\/841749","volume":"2011","author":"HD Mistry","year":"2011","unstructured":"Mistry HD, Williams PJ. The importance of antioxidant micronutrients in pregnancy. Oxid Med Cell Longev. 2011;2011:841749. https:\/\/doi.org\/10.1155\/2011\/841749.","journal-title":"Oxid Med Cell Longev"},{"issue":"5","key":"3375_CR116","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.nutres.2015.04.004","volume":"35","author":"A Basu","year":"2015","unstructured":"Basu A, Yu JY, Jenkins AJ, Nankervis AJ, Hanssen KF, Henriksen T, et al. Trace elements as predictors of preeclampsia in type 1 diabetic pregnancy. Nutri Res (New York, NY). 2015;35(5):421\u201330. https:\/\/doi.org\/10.1016\/j.nutres.2015.04.004.","journal-title":"Nutri Res (New York, NY)"},{"key":"3375_CR117","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.envint.2018.11.009","volume":"122","author":"Y Hao","year":"2019","unstructured":"Hao Y, Pang Y, Yan H, Zhang Y, Liu J, Jin L, et al. Association of maternal serum copper during early pregnancy with the risk of spontaneous preterm birth: a nested case-control study in China. Environ Int. 2019;122:237\u201343. https:\/\/doi.org\/10.1016\/j.envint.2018.11.009.","journal-title":"Environ Int"},{"issue":"5","key":"3375_CR118","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1097\/AOG.0b013e31818aa5b5","volume":"112","author":"JM Catov","year":"2008","unstructured":"Catov JM, Bodnar LM, Hackney D, Roberts JM, Simhan HN. Activation of the fibrinolytic cascade early in pregnancy among women with spontaneous preterm birth. Obstet Gynecol. 2008;112(5):1116\u201322. https:\/\/doi.org\/10.1097\/AOG.0b013e31818aa5b5.","journal-title":"Obstet Gynecol"},{"issue":"6","key":"3375_CR119","doi-asserted-by":"publisher","first-page":"610.e1","DOI":"10.1016\/j.ajog.2007.04.024","volume":"197","author":"JM Catov","year":"2007","unstructured":"Catov JM, Bodnar LM, Kip KE, Hubel C, Ness RB, Harger G, et al. Early pregnancy lipid concentrations and spontaneous preterm birth. Am J Obstet Gynecol. 2007;197(6):610.e1-7. https:\/\/doi.org\/10.1016\/j.ajog.2007.04.024.","journal-title":"Am J Obstet Gynecol"},{"issue":"6","key":"3375_CR120","doi-asserted-by":"publisher","first-page":"619","DOI":"10.4065\/76.6.619","volume":"76","author":"C Napoli","year":"2001","unstructured":"Napoli C, Lerman LO. Involvement of oxidation-sensitive mechanisms in the cardiovascular effects of hypercholesterolemia. Mayo Clin Proc. 2001;76(6):619\u201331. https:\/\/doi.org\/10.4065\/76.6.619.","journal-title":"Mayo Clin Proc"},{"key":"3375_CR121","doi-asserted-by":"publisher","first-page":"9435972","DOI":"10.1155\/2020\/9435972","volume":"2020","author":"G Chiudzu","year":"2020","unstructured":"Chiudzu G, Choko AT, Maluwa A, Huber S, Odland J. Maternal serum concentrations of selenium, copper, and zinc during pregnancy are associated with risk of spontaneous preterm birth: a case-control study from Malawi. J Pregnancy. 2020;2020:9435972. https:\/\/doi.org\/10.1155\/2020\/9435972.","journal-title":"J Pregnancy"},{"issue":"6","key":"3375_CR122","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/0002-9378(71)90805-2","volume":"109","author":"S Burrows","year":"1971","unstructured":"Burrows S, Pekala B. Serum copper and ceruloplasmin in pregnancy. Am J Obstet Gynecol. 1971;109(6):907\u20139. https:\/\/doi.org\/10.1016\/0002-9378(71)90805-2.","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"3375_CR123","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3109\/00016346709158191","volume":"46","author":"NE Borglin","year":"1967","unstructured":"Borglin NE, Heijkenskj\u00f6ld F. Studies on serum copper in pregnancy. Acta Obstet Gynecol Scand. 1967;46(2):119\u201325.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"7","key":"3375_CR124","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1097\/jcma.0000000000000077","volume":"82","author":"K Turan","year":"2019","unstructured":"Turan K, Arslan A, U\u00e7kan K, Demir H, Demir C. Change of the levels of trace elements and heavy metals in threatened abortion. J Chinese Med Assoc: JCMA. 2019;82(7):554\u20137. https:\/\/doi.org\/10.1097\/jcma.0000000000000077.","journal-title":"J Chinese Med Assoc: JCMA"},{"issue":"5","key":"3375_CR125","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1097\/AOG.0b013e3181da8d38","volume":"115","author":"JA Lykke","year":"2010","unstructured":"Lykke JA, Dideriksen KL, Lidegaard \u00d8, Langhoff-Roos J. First-trimester vaginal bleeding and complications later in pregnancy. Obstet Gynecol. 2010;115(5):935\u201344. https:\/\/doi.org\/10.1097\/AOG.0b013e3181da8d38.","journal-title":"Obstet Gynecol"},{"key":"3375_CR126","doi-asserted-by":"publisher","unstructured":"Saraswat L, Bhattacharya S, Maheshwari A, Bhattacharya S. Maternal and perinatal outcome in women with threatened miscarriage in the first trimester: a systematic review. BJOG: an Intl J Obstet Gynaecol. 2010;117(3):245\u201357. https:\/\/doi.org\/10.1111\/j.1471-0528.2009.02427.x.","DOI":"10.1111\/j.1471-0528.2009.02427.x"},{"issue":"3","key":"3375_CR127","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.ajog.2003.09.023","volume":"190","author":"JL Weiss","year":"2004","unstructured":"Weiss JL, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, et al. Threatened abortion: a risk factor for poor pregnancy outcome, a population-based screening study. Am J Obstet Gynecol. 2004;190(3):745\u201350. https:\/\/doi.org\/10.1016\/j.ajog.2003.09.023.","journal-title":"Am J Obstet Gynecol"},{"issue":"2\u20133","key":"3375_CR128","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.jtemb.2005.08.002","volume":"19","author":"A Alebic-Juretic","year":"2005","unstructured":"Alebic-Juretic A, Frkovic A. Plasma copper concentrations in pathological pregnancies. J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS). 2005;19(2\u20133):191\u20134. https:\/\/doi.org\/10.1016\/j.jtemb.2005.08.002.","journal-title":"J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)"},{"issue":"11","key":"3375_CR129","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1007\/bf02828116","volume":"71","author":"P Pathak","year":"2004","unstructured":"Pathak P, Kapil U. Role of trace elements zinc, copper and magnesium during pregnancy and its outcome. Indian J Pediatr. 2004;71(11):1003\u20135. https:\/\/doi.org\/10.1007\/bf02828116.","journal-title":"Indian J Pediatr"},{"issue":"4","key":"3375_CR130","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1079\/pns2004385","volume":"63","author":"L Gambling","year":"2004","unstructured":"Gambling L, McArdle HJ. Iron, copper and fetal development. Proc Nutr Soc. 2004;63(4):553\u201362. https:\/\/doi.org\/10.1079\/pns2004385.","journal-title":"Proc Nutr Soc"},{"issue":"5 Suppl","key":"3375_CR131","doi-asserted-by":"publisher","first-page":"996s","DOI":"10.1093\/ajcn\/67.5.996S","volume":"67","author":"RB Rucker","year":"1998","unstructured":"Rucker RB, Kosonen T, Clegg MS, Mitchell AE, Rucker BR, Uriu-Hare JY, et al. Copper, lysyl oxidase, and extracellular matrix protein cross-linking. Am J Clin Nutr. 1998;67(5 Suppl):996s\u20131002s. https:\/\/doi.org\/10.1093\/ajcn\/67.5.996S.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"3375_CR132","first-page":"7","volume":"41","author":"HD Zhang","year":"2006","unstructured":"Zhang HD, Chen HC, Shan LF. Study on the relationship between copper, lysyl oxidase and premature rupture of membranes. Zhonghua Fu Chan Ke Za Zhi. 2006;41(1):7\u201311.","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"3375_CR133","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.jtemb.2019.08.009","volume":"56","author":"MG Skalnaya","year":"2019","unstructured":"Skalnaya MG, Tinkov AA, Lobanova YN, Chang JS, Skalny AV. Serum levels of copper, iron, and manganese in women with pregnancy, miscarriage, and primary infertility. J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS). 2019;56:124\u201330. https:\/\/doi.org\/10.1016\/j.jtemb.2019.08.009.","journal-title":"J Trace Elem Med Biol Organ Soc Min Trace Elem (GMS)"},{"issue":"6","key":"3375_CR134","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1080\/15513815.2023.2245892","volume":"42","author":"M Sengul","year":"2023","unstructured":"Sengul M, Karadas B, Acar-Sahan S, Simsek F, Horoz E, \u00d6zok IC, et al. Functional and histological changes in umbilical artery and myometrium isolated from IUGR complicated pregnancies. Fetal Pediatr Pathol. 2023;42(6):845\u201359. https:\/\/doi.org\/10.1080\/15513815.2023.2245892.","journal-title":"Fetal Pediatr Pathol"},{"key":"3375_CR135","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1824-7288-37-41","volume":"37","author":"T Saleem","year":"2011","unstructured":"Saleem T, Sajjad N, Fatima S, Habib N, Ali SR, Qadir M. Intrauterine growth retardation\u2013small events, big consequences. Ital J Pediatr. 2011;37:41. https:\/\/doi.org\/10.1186\/1824-7288-37-41.","journal-title":"Ital J Pediatr"},{"issue":"11","key":"3375_CR136","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1111\/ped.13409","volume":"59","author":"C Kojima","year":"2017","unstructured":"Kojima C, Shoji H, Ikeda N, Kitamura T, Hisata K, Shimizu T. Association of zinc and copper with clinical parameters in the preterm newborn. Pediatr Intl: Official J Japan Pediatr Soc. 2017;59(11):1165\u20138. https:\/\/doi.org\/10.1111\/ped.13409.","journal-title":"Pediatr Intl: Official J Japan Pediatr Soc"},{"issue":"11","key":"3375_CR137","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.3390\/nu4111747","volume":"4","author":"CE West","year":"2012","unstructured":"West CE, Dunstan J, McCarthy S, Metcalfe J, D\u2019Vaz N, Meldrum S, et al. Associations between maternal antioxidant intakes in pregnancy and infant allergic outcomes. Nutrients. 2012;4(11):1747\u201358. https:\/\/doi.org\/10.3390\/nu4111747.","journal-title":"Nutrients"},{"key":"3375_CR138","doi-asserted-by":"publisher","unstructured":"Di Toro R, Galdo Capotorti G, Gialanella G, Miraglia del Giudice M, Moro R, Perrone L. Zinc and copper status of allergic children. Acta Paediatrica Scandinavica. 1987;76(4):612\u20137. https:\/\/doi.org\/10.1111\/j.1651-2227.1987.tb10530.x.","DOI":"10.1111\/j.1651-2227.1987.tb10530.x"},{"issue":"1","key":"3375_CR139","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1006\/geno.1994.1341","volume":"22","author":"AM George","year":"1994","unstructured":"George AM, Reed V, Glenister P, Chelly J, T\u00fcmer Z, Horn N, et al. Analysis of Mnk, the murine homologue of the locus for Menkes disease, in normal and mottled (Mo) mice. Genomics. 1994;22(1):27\u201335. https:\/\/doi.org\/10.1006\/geno.1994.1341.","journal-title":"Genomics"},{"issue":"460","key":"3375_CR140","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1038\/249852a0","volume":"249","author":"DM Hunt","year":"1974","unstructured":"Hunt DM. Primary defect in copper transport underlies mottled mutants in the mouse. Nature. 1974;249(460):852\u20134. https:\/\/doi.org\/10.1038\/249852a0.","journal-title":"Nature"},{"issue":"5","key":"3375_CR141","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1093\/oxfordjournals.jhered.a108423","volume":"64","author":"CH Yoon","year":"1973","unstructured":"Yoon CH. Recent advances in Syrian hamster genetics. J Hered. 1973;64(5):305\u20137. https:\/\/doi.org\/10.1093\/oxfordjournals.jhered.a108423.","journal-title":"J Hered"},{"issue":"2","key":"3375_CR142","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1038\/ng0696-219","volume":"13","author":"EJ Kelly","year":"1996","unstructured":"Kelly EJ, Palmiter RD. A murine model of Menkes disease reveals a physiological function of metallothionein. Nat Genet. 1996;13(2):219\u201322. https:\/\/doi.org\/10.1038\/ng0696-219.","journal-title":"Nat Genet"},{"key":"3375_CR143","doi-asserted-by":"crossref","unstructured":"Doolitile Dp, Davisson Mt, Guidi jN, Green Mc. Catalog of mutant genes and polymorphic loci. In: Lyon MF, Rastan S, Brown SDM, editors. Genetic variants and strains of the Laboratory mouse. Oxford University Press; 1996. p. 0.","DOI":"10.1093\/oso\/9780198548690.003.0002"},{"issue":"6","key":"3375_CR144","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1258\/shorts.2010.010069","volume":"1","author":"T Young","year":"2010","unstructured":"Young T, Downey G, Maheshwari MB, Nicholl DJ. A cupric pregnancy - thirteenth time lucky. JRSM Short Reports. 2010;1(6):51. https:\/\/doi.org\/10.1258\/shorts.2010.010069.","journal-title":"JRSM Short Reports"},{"issue":"9","key":"3375_CR145","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1093\/hmg\/8.9.1665","volume":"8","author":"OI Buiakova","year":"1999","unstructured":"Buiakova OI, Xu J, Lutsenko S, Zeitlin S, Das K, Das S, et al. Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation. Hum Mol Genet. 1999;8(9):1665\u201371. https:\/\/doi.org\/10.1093\/hmg\/8.9.1665.","journal-title":"Hum Mol Genet"},{"issue":"3","key":"3375_CR146","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1093\/oxfordjournals.jhered.a109751","volume":"74","author":"H Rauch","year":"1983","unstructured":"Rauch H. Toxic milk, a new mutation affecting cooper metabolism in the mouse. J Hered. 1983;74(3):141\u20134. https:\/\/doi.org\/10.1093\/oxfordjournals.jhered.a109751.","journal-title":"J Hered"},{"issue":"2","key":"3375_CR147","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1007\/s11033-021-06192-5","volume":"48","author":"K Hadrian","year":"2021","unstructured":"Hadrian K, Przyby\u0142kowski A. Toxic milk mice models of Wilson\u2019s disease. Mol Biol Rep. 2021;48(2):1903\u201314. https:\/\/doi.org\/10.1007\/s11033-021-06192-5.","journal-title":"Mol Biol Rep"}],"container-title":["Journal of Assisted Reproduction and Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03375-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10815-024-03375-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10815-024-03375-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T07:32:49Z","timestamp":1743319969000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10815-024-03375-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":147,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["3375"],"URL":"https:\/\/doi.org\/10.1007\/s10815-024-03375-4","relation":{},"ISSN":["1058-0468","1573-7330"],"issn-type":[{"value":"1058-0468","type":"print"},{"value":"1573-7330","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,10]]},"assertion":[{"value":"19 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All co-authors have approved its publication, and the responsible authorities have approved its publication at the institution where the work is carried out.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}