{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:42:40Z","timestamp":1793148160249,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:00:00Z","timestamp":1521849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Interv Card Electrophysiol"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s10840-018-0352-0","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T01:42:38Z","timestamp":1521855758000},"page":"141-148","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["High rate of persistent iatrogenic atrial septal defect after single transseptal puncture for cryoballoon pulmonary vein isolation"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4840-6192","authenticated-orcid":false,"given":"Markus","family":"Linhart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica T.","family":"Werner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"St\u00f6ckigt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika T.","family":"Kohlmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia C.","family":"Lodde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz P. T.","family":"Linneborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Beiert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Hammerstingl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Borr\u00e0s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Nickenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9 P.","family":"Andri\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan W.","family":"Schrickel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,24]]},"reference":[{"issue":"15","key":"352_CR1","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1161\/CIRCULATIONAHA.105.592055","volume":"114","author":"G Webb","year":"2006","unstructured":"Webb G, Gatzoulis MA. Atrial septal defects in the adult: recent progress and overview. Circulation. 2006;114(15):1645\u201353.","journal-title":"Circulation"},{"issue":"10","key":"352_CR2","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1093\/europace\/eur138","volume":"13","author":"NY Chan","year":"2011","unstructured":"Chan NY, Choy CC, Lau CL, Lo YK, Chu PS, Yuen HC, et al. Persistent iatrogenic atrial septal defect after pulmonary vein isolation by cryoballoon: an under-recognized complication. Europace. 2011;13(10):1406\u201310.","journal-title":"Europace"},{"issue":"2","key":"352_CR3","doi-asserted-by":"publisher","first-page":"362 e1","DOI":"10.1016\/j.ahj.2006.04.034","volume":"152","author":"C Hammerstingl","year":"2006","unstructured":"Hammerstingl C, Lickfett L, Jeong KM, Troatz C, Wedekind JA, Tiemann K, et al. Persistence of iatrogenic atrial septal defect after pulmonary vein isolation\u2014an underestimated risk? Am Heart J. 2006;152(2):362 e1\u20135.","journal-title":"Am Heart J"},{"issue":"3","key":"352_CR4","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1093\/europace\/eup428","volume":"12","author":"A Rillig","year":"2010","unstructured":"Rillig A, Meyerfeldt U, Kunze M, Birkemeyer R, Miljak T, Jackle S, et al. Persistent iatrogenic atrial septal defect after a single-puncture, double-transseptal approach for pulmonary vein isolation using a remote robotic navigation system: results from a prospective study. Europace. 2010;12(3):331\u20136.","journal-title":"Europace"},{"issue":"10","key":"352_CR5","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1111\/j.1540-8159.2004.00646.x","volume":"27","author":"O Obel","year":"2004","unstructured":"Obel O, Mansour M, Picard M, Ruskin J, Keane D. Persistence of septal defects after transseptal puncture for pulmonary vein isolation procedures. Pacing Clin Electrophysiol. 2004;27(10):1411\u20134.","journal-title":"Pacing Clin Electrophysiol"},{"issue":"16","key":"352_CR6","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/j.jacc.2013.07.017","volume":"62","author":"EM Cronin","year":"2013","unstructured":"Cronin EM, Collier P, Wazni OM, Griffin BP, Jaber WA, Saliba WI. Persistence of atrial septal defect after cryoballoon ablation of atrial fibrillation. J Am Coll Cardiol. 2013;62(16):1491\u20132.","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"352_CR7","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1111\/j.1540-8183.2011.00630.x","volume":"24","author":"PM McGinty","year":"2011","unstructured":"McGinty PM, Smith TW, Rogers JH. Transseptal left heart catheterization and the incidence of persistent iatrogenic atrial septal defects. J Interv Cardiol. 2011;24(3):254\u201363.","journal-title":"J Interv Cardiol"},{"issue":"12","key":"352_CR8","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1111\/j.1540-8167.2009.01560.x","volume":"20","author":"M Linhart","year":"2009","unstructured":"Linhart M, Bellmann B, Mittmann-Braun E, Schrickel JW, Bitzen A, Andrie R, et al. Comparison of cryoballoon and radiofrequency ablation of pulmonary veins in 40 patients with paroxysmal atrial fibrillation: a case-control study. J Cardiovasc Electrophysiol. 2009;20(12):1343\u20138.","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"4","key":"352_CR9","doi-asserted-by":"publisher","first-page":"e149","DOI":"10.1016\/j.jacc.2006.07.018","volume":"48","author":"V Fuster","year":"2006","unstructured":"Fuster V, Ryd\u00e9n LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. ACC\/AHA\/ESC 2006 guidelines for the management of patients with atrial fibrillation. J Am Coll Cardiol. 2006;48(4):e149\u2013246.","journal-title":"J Am Coll Cardiol."},{"issue":"21","key":"352_CR10","doi-asserted-by":"publisher","first-page":"2719","DOI":"10.1093\/eurheartj\/ehs253","volume":"33","author":"AJ Camm","year":"2012","unstructured":"Camm AJ, Lip GY, de Caterina R, Savelieva I, Atar D, Hohnloser SH, et al. Focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Eur Heart J. 2012;33(21):2719\u201347.","journal-title":"Eur Heart J"},{"issue":"7","key":"352_CR11","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/S0002-9149(00)01078-X","volume":"86","author":"Y Agmon","year":"2000","unstructured":"Agmon Y, Khandheria BK, Meissner I, Schwartz GL, Petterson TM, O'Fallon WM, et al. Left atrial appendage flow velocities in subjects with normal left ventricular function. Am J Cardiol. 2000;86(7):769\u201373.","journal-title":"Am J Cardiol"},{"issue":"7","key":"352_CR12","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.jcmg.2010.01.007","volume":"3","author":"BS Rana","year":"2010","unstructured":"Rana BS, Thomas MR, Calvert PA, Monaghan MJ, Hildick-Smith D. Echocardiographic evaluation of patent foramen ovale prior to device closure. JACC Cardiovasc Imaging. 2010;3(7):749\u201360.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"74","key":"352_CR13","doi-asserted-by":"publisher","first-page":"862","DOI":"10.4065\/74.9.862","volume":"74","author":"I Meissner","year":"1999","unstructured":"Meissner I, Whisnant JP, Khanderia BK, Spittell PC, O'Fallon WM, Pascoe RD, et al. Prevalence of potential risk factors for stroke assessed by transesophageal echocardiography and carotid ultrasonography: the SPARC Study. Mayo Clin Proc. 1999;74(74):862\u20139.","journal-title":"Mayo Clin Proc"},{"issue":"8","key":"352_CR14","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1016\/j.echo.2015.05.015","volume":"28","author":"FE Silvestry","year":"2015","unstructured":"Silvestry FE, Cohen MS, Armsby LB, Burkule NJ, Fleishman CE, Hijazi ZM, et al. Guidelines for the echocardiographic assessment of atrial septal defect and patent foramen ovale: from the American Society of Echocardiography and Society for Cardiac Angiography and Interventions. J Am Soc Echocardiogr. 2015;28(8):910\u201358.","journal-title":"J Am Soc Echocardiogr"},{"issue":"24","key":"352_CR15","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.1056\/NEJMoa011503","volume":"345","author":"J-L Mas","year":"2001","unstructured":"Mas J-L, Arquizan C, Lamy C, Zuber M, Cabanes L, Derumeaux G, et al. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med. 2001;345(24):1740\u20136.","journal-title":"N Engl J Med"},{"issue":"7","key":"352_CR16","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1016\/j.amjcard.2010.11.031","volume":"107","author":"I Ben-Dor","year":"2011","unstructured":"Ben-Dor I, Goldstein SA, Pichard AD, Satler LF, Maluenda G, Li Y, et al. Clinical profile, prognostic implication, and response to treatment of pulmonary hypertension in patients with severe aortic stenosis. Am J Cardiol. 2011;107(7):1046\u201351.","journal-title":"Am J Cardiol"},{"issue":"1","key":"352_CR17","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1111\/jce.12279","volume":"25","author":"J Sieira","year":"2014","unstructured":"Sieira J, Chierchia GB, Di Giovanni G, Conte G, de AC, Sarkozy A, et al. One year incidence of iatrogenic atrial septal defect after cryoballoon ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2014;25(1):11\u20135.","journal-title":"J Cardiovasc Electrophysiol."},{"issue":"1","key":"352_CR18","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s10840-016-0193-7","volume":"48","author":"A Davies","year":"2017","unstructured":"Davies A, Gunaruwan P, Collins N, Barlow M, Jackson N, Leitch J. Persistent iatrogenic atrial septal defects after pulmonary vein isolation: long-term follow-up with contrast transesophageal echocardiography. J Interv Card Electrophysiol. 2017;48(1):99\u2013103.","journal-title":"J Interv Card Electrophysiol"},{"issue":"9","key":"352_CR19","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1111\/pace.12663","volume":"38","author":"G Mugnai","year":"2015","unstructured":"Mugnai G, Sieira J, Ciconte G, Hervas MS, Irfan G, Saitoh Y, et al. One year incidence of atrial septal defect after PV isolation: a comparison between conventional radiofrequency and cryoballoon ablation. Pacing Clin Electrophysiol. 2015;38(9):1049\u201357.","journal-title":"Pacing Clin Electrophysiol."},{"issue":"6","key":"352_CR20","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1093\/eurheartj\/ehn570","volume":"30","author":"K-RJ Chun","year":"2009","unstructured":"Chun K-RJ, Schmidt B, Metzner A, Tilz R, Zerm T, Koster I, et al. The \u2018single big cryoballoon\u2019 technique for acute pulmonary vein isolation in patients with paroxysmal atrial fibrillation: a prospective observational single centre study. Eur Heart J. 2009;30(6):699\u2013709.","journal-title":"Eur Heart J"},{"issue":"23","key":"352_CR21","doi-asserted-by":"publisher","first-page":"2235","DOI":"10.1056\/NEJMoa1602014","volume":"374","author":"K-H Kuck","year":"2016","unstructured":"Kuck K-H, Brugada J, Furnkranz A, Metzner A, Ouyang F, Chun KRJ, et al. Cryoballoon or radiofrequency ablation for paroxysmal atrial fibrillation. N Engl J Med. 2016;374(23):2235\u201345.","journal-title":"N Engl J Med"},{"key":"352_CR22","volume":"100","author":"ME Rich","year":"2015","unstructured":"Rich ME, Tseng A, Lim HW, Wang PJ, Su WW. Reduction of iatrogenic atrial septal defects with an anterior and inferior transseptal puncture site when operating the cryoballoon ablation catheter. J Vis Exp. 2015;100:e52811.","journal-title":"J Vis Exp"},{"issue":"7","key":"352_CR23","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.1016\/S0735-1097(99)00472-6","volume":"34","author":"Y Agmon","year":"1999","unstructured":"Agmon Y, Khandheria BK, Gentile F, Seward JB. Echocardiographic assessment of the left atrial appendage. J Am Coll Cardiol. 1999;34(7):1867\u201377.","journal-title":"J Am Coll Cardiol."},{"issue":"15","key":"352_CR24","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1136\/hrt.2010.196147","volume":"96","author":"A Hoffmann","year":"2010","unstructured":"Hoffmann A, Chockalingam P, Balint OH, Dadashev A, Dimopoulos K, Engel R, et al. Cerebrovascular accidents in adult patients with congenital heart disease. Heart. 2010;96(15):1223\u20136.","journal-title":"Heart"},{"key":"352_CR25","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/1471-2261-14-38","volume":"14","author":"Y-S Lin","year":"2014","unstructured":"Lin Y-S, Liu P-H, Wu L-S, Chen Y-M, Chang C-J, Chu P-H. Major adverse cardiovascular events in adult congenital heart disease: a population-based follow-up study from Taiwan. BMC Cardiovasc Disord. 2014;14:38.","journal-title":"BMC Cardiovasc Disord"},{"issue":"2","key":"352_CR26","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.ijcard.2014.05.007","volume":"175","author":"TO Cheng","year":"2014","unstructured":"Cheng TO. All atrial septal defects should be closed. Int J Cardiol. 2014;175(2):224\u20135.","journal-title":"Int J Cardiol"},{"issue":"3","key":"352_CR27","first-page":"258","volume":"10","author":"J-Y Chen","year":"2013","unstructured":"Chen J-Y, Zhang A-D, Lu H-Y, Guo J, Wang F-F, Li Z-C. CHADS2 versus CHA2DS2-VASc score in assessing the stroke and thromboembolism risk stratification in patients with atrial fibrillation: a systematic review and meta-analysis. J Geriatr Cardiol. 2013;10(3):258\u201366.","journal-title":"J Geriatr Cardiol"},{"issue":"3","key":"352_CR28","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.jcin.2014.10.024","volume":"8","author":"R Schueler","year":"2015","unstructured":"Schueler R, Ozturk C, Wedekind JA, Werner N, Stockigt F, Mellert F, et al. ersistence of iatrogenic atrial septal defect after interventional mitral valve repair with the MitraClip system: a note of caution. JACC Cardiovasc Interv. 2015;8(3):450\u20139.","journal-title":"JACC Cardiovasc Interv"},{"issue":"4","key":"352_CR29","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1111\/jce.12608","volume":"26","author":"T Deneke","year":"2015","unstructured":"Deneke T, Jais P, Scaglione M, Schmitt R, Di Biase L, Christopoulos G, et al. Silent cerebral events\/lesions related to atrial fibrillation ablation: a clinical review. J Cardiovasc Electrophysiol. 2015;26(4):455\u201363.","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"3","key":"352_CR30","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s10840-015-0004-6","volume":"43","author":"C Bary von","year":"2015","unstructured":"von Bary C, Deneke T, Arentz T, Schade A, Lehrmann H, Eissnert C, et al. Silent cerebral events as a result of left atrial catheter ablation do not cause neuropsychological sequelae\u2014a MRI-controlled multicenter study. J Interv Card Electrophysiol. 2015;43(3):217\u201326.","journal-title":"J Interv Card Electrophysiol"},{"issue":"7","key":"352_CR31","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1164\/rccm.200811-1691OC","volume":"179","author":"MR Fisher","year":"2009","unstructured":"Fisher MR, Forfia PR, Chamera E, Housten-Harris T, Champion HC, Girgis RE, et al. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med. 2009;179(7):615\u201321.","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Journal of Interventional Cardiac Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10840-018-0352-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10840-018-0352-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10840-018-0352-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,23]],"date-time":"2019-03-23T20:09:34Z","timestamp":1553371774000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10840-018-0352-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,24]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["352"],"URL":"https:\/\/doi.org\/10.1007\/s10840-018-0352-0","relation":{},"ISSN":["1383-875X","1572-8595"],"issn-type":[{"value":"1383-875X","type":"print"},{"value":"1572-8595","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,24]]},"assertion":[{"value":"8 November 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the local ethics committee (Ethikkommission an der Medizinischen Fakult\u00e4t der Rheinischen Friedrich-Wilhelms-Universit\u00e4t Bonn, approval no. 353\/13) and was carried out in concordance with the Declaration of Helsinki. All patients gave written informed consent before study inclusion.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}