{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:25:12Z","timestamp":1788467112910,"version":"build-2803163510"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Departmental sources of the National Heart Institute."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Interv Card Electrophysiol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>While studies comparing the effectiveness of remifentanil and dexmedetomidine are prevalent in other nations, using remifentanil alone is uncommon in Malaysia. This research aims to evaluate the effectiveness of sedation with remifentanil or dexmedetomidine infusion in monitored anesthesia care for electrophysiology procedures.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This study is a single-center, single-blinded, prospective randomized clinical study. One hundred twenty patients were randomized into two groups (remifentanil vs dexmedetomidine). Demographic characteristics and clinical outcomes, including level of sedation, vital signs, and patient satisfaction were monitored and recorded.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Group R showed a higher mean observer\u2019s assessment of alertness\/sedation score (3.9\u2009\u00b1\u20090.7 vs 3.6\u2009\u00b1\u20090.8; <jats:italic>p<\/jats:italic>\u2009=\u20090.008), mean arterial pressure (92.0\u2009\u00b1\u200912.0 vs 83.0\u2009\u00b1\u200913.0\u00a0mmHg; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), heart rate (82.0\u2009\u00b1\u200920.0 vs 73.0\u2009\u00b1\u200918.0 beats\/min; <jats:italic>p<\/jats:italic>\u2009=\u20090.006), systolic blood pressure (139.0\u2009\u00b1\u200916.0 vs 123.0\u2009\u00b1\u200917.0\u00a0mmHg; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and diastolic blood pressure (75.0\u2009\u00b1\u200913.0 vs 69.0\u2009\u00b1\u200914.0\u00a0mmHg; <jats:italic>p<\/jats:italic>\u2009=\u20090.009) than Group D. Oxygen saturation (99.0\u2009\u00b1\u20091.0%; <jats:italic>p<\/jats:italic>\u2009=\u20090.220) and respiration rate (16.0\u2009\u00b1\u20093.0 breaths\/min; <jats:italic>p<\/jats:italic>\u2009=\u20090.361) for both groups were the same. Adverse events, including hypotension, bradycardia, and respiratory depression were observed in both groups. Both groups gave positive responses ranging from fair to good for patient satisfaction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Dexmedetomidine is a better choice of anesthesia as it was associated with a higher level of sedation, more stable hemodynamics, lower incidence of adverse events, and better patient satisfaction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s10840-024-01884-x","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T12:04:50Z","timestamp":1723032290000},"page":"1735-1743","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Randomized single-blinded study comparing sedation effectiveness and hemodynamic stability of remifentanil vs dexmedetomidine infusion for electrophysiology procedures in patients of National Heart Institute cathlab"],"prefix":"10.1007","volume":"67","author":[{"given":"Rozaini","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azlee Abdul","family":"Mutalib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen Yi","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirpal Singh","family":"Sachdev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farkad Abdul","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther Siew Lee","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"key":"1884_CR1","doi-asserted-by":"publisher","unstructured":"de Lepper AGW, Buck CMA, van \u2019t Veer M, Huberts W, van de Vosse FN, Dekker LRC. 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