{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T09:41:29Z","timestamp":1792575689272,"version":"4.5.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Interv Card Electrophysiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ventricular tachycardia (VT) ablation is a high-risk procedure that often requires induction of VT for activation and entrainment mapping. VT induction, particularly those with rapid cycle lengths tends to predispose patients to acute hemodynamic instability, sometimes necessitating mechanical circulatory support (MCS) to maintain perfusion, especially during longer procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>We sought to evaluate clinical and procedural outcomes in patients requiring MCS during VT ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We queried the 2017\u20132021 National Inpatient Sample (NIS) database and identified patients who underwent VT ablation using ICD-10 codes. Patients were stratified based on the use of MCS during VT ablation. MCS devices included intra-aortic balloon pump (IABP), percutaneous ventricular assist device (pVAD), and extracorporeal membrane oxygenation (ECMO). We then compared clinical outcomes and utilization of resources between the two groups (VT ablation with MCS vs. VT ablation without MCS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 10,980 patients underwent VT ablations during the specified time period of 2017\u20132021 and of these, 815 (7.42%) required MCS during the ablation procedure. The patients who required MCS had a significantly higher in-hospital mortality as compared to those who did not require MCS (16.56% vs. 2.26%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The use of MCS was also associated with a relatively longer length of inpatient stay (mean: 18 vs. 6\u00a0days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) and also incurred a greater cost of hospitalization (USD 538,598 vs. 200,308,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The risk of inpatient complications (such as acute kidney injury, stroke, cardiac tamponade, bleeding and vascular complications) was also observed to be higher in the group of patients requiring MCS vs. the group which did not require MCS during VT ablation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The utilization of MCS during VT ablation was associated with significantly worse inpatient outcomes, post-procedural complications and a longer stay in the hospital. It is plausible that patients requiring MCS during VT ablation represent a relatively sicker subset of patients. Despite the use of MCS to prevent hemodynamic compromise during VT ablation, the post-procedural outcomes remain poorer. Our findings also suggest that an individualized strategy for the use of MCS might be more useful than an empiric use of MCS during VT ablation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10840-026-02249-2","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:36:08Z","timestamp":1772170568000},"page":"1909-1917","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of mechanical circulatory support use with inpatient outcomes in patients undergoing ventricular tachycardia ablation"],"prefix":"10.1007","volume":"69","author":[{"given":"Nahush","family":"Bansal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishnavi","family":"Aradhyula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navkirat","family":"Kahlon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urja","family":"Sanghvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Moukarbel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Chacko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab","family":"Eltahawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komandoor","family":"Srivathsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Sorajja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Maan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"issue":"2","key":"2249_CR1","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1056\/NEJMoa1513614","volume":"375","author":"JL Sapp","year":"2016","unstructured":"Sapp JL, et al. Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs. N Engl J Med. 2016;375(2):111\u201321. https:\/\/doi.org\/10.1056\/NEJMoa1513614.","journal-title":"N Engl J Med"},{"issue":"13","key":"2249_CR2","doi-asserted-by":"publisher","first-page":"e210","DOI":"10.1161\/CIR.0000000000000548","volume":"138","author":"SM Al-Khatib","year":"2018","unstructured":"Al-Khatib SM, et al. 2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2018;138(13):e210\u201371. https:\/\/doi.org\/10.1161\/CIR.0000000000000548.","journal-title":"Circulation"},{"issue":"21","key":"2249_CR3","doi-asserted-by":"publisher","first-page":"2750","DOI":"10.1161\/CIRCULATIONAHA.106.655720","volume":"115","author":"WG Stevenson","year":"2007","unstructured":"Stevenson WG, Soejima K. Catheter ablation for ventricular tachycardia. Circulation. 2007;115(21):2750\u201360. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.106.655720.","journal-title":"Circulation"},{"issue":"4","key":"2249_CR4","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.hrthm.2012.12.013","volume":"10","author":"R Tung","year":"2013","unstructured":"Tung R, et al. Epicardial ablation of ventricular tachycardia: an institutional experience of safety and efficacy. Heart Rhythm. 2013;10(4):490\u20138. https:\/\/doi.org\/10.1016\/j.hrthm.2012.12.013.","journal-title":"Heart Rhythm"},{"issue":"1","key":"2249_CR5","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1161\/CIRCEP.114.002155","volume":"8","author":"P Santangeli","year":"2015","unstructured":"Santangeli P, et al. Acute hemodynamic decompensation during catheter ablation of scar-related ventricular tachycardia: incidence, predictors, and impact on mortality. Circ Arrhythm Electrophysiol. 2015;8(1):68\u201375. https:\/\/doi.org\/10.1161\/CIRCEP.114.002155.","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2249_CR6","doi-asserted-by":"publisher","first-page":"S98","DOI":"10.1016\/j.cardfail.2022.03.250","volume":"28","author":"M Agarwal","year":"2022","unstructured":"Agarwal M, Garg L, Ziaeian B, Bradfield J, Fonarow G. National trends in the utilization of short-term mechanical circulatory support devices during ventricular tachycardia ablation related hospitalizations. J Card Fail. 2022;28:S98\u20139.","journal-title":"J Card Fail"},{"issue":"1","key":"2249_CR7","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.hrthm.2022.08.037","volume":"20","author":"NVK Pothineni","year":"2023","unstructured":"Pothineni NVK, et al. Outcomes of a PAINESD score-guided multidisciplinary management approach for patients with ventricular tachycardia storm and advanced heart failure: a pilot study. Heart Rhythm. 2023;20(1):134\u20139. https:\/\/doi.org\/10.1016\/j.hrthm.2022.08.037.","journal-title":"Heart Rhythm"},{"issue":"4","key":"2249_CR8","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1111\/aor.14877","volume":"49","author":"K Hashimoto","year":"2025","unstructured":"Hashimoto K, Akkawi AR, Ghazal M, Briasoulis A, Kuno T. Impact of mechanical circulatory support on in-hospital outcomes among patients with ventricular tachycardia requiring ablation. Artif Organs. 2025;49(4):681\u201390. https:\/\/doi.org\/10.1111\/aor.14877.","journal-title":"Artif Organs"},{"key":"2249_CR9","doi-asserted-by":"publisher","unstructured":"Akkawi, Abdul Rahman, Chehab, Omar, Briasoulis, Alexandros Abstract 18575: Impact of Mechanical Circulatory Support on In-Hospital Mortality in Ventricular Tachycardia Ablation: A United States Nationwide Analysis. Circulation 2023;148. https:\/\/doi.org\/10.1161\/circ.148.suppl_1.18575.","DOI":"10.1161\/circ.148.suppl_1.18575"},{"issue":"6","key":"2249_CR10","doi-asserted-by":"publisher","first-page":"e004717","DOI":"10.1161\/CIRCEP.116.004717","volume":"10","author":"S Kusa","year":"2017","unstructured":"Kusa S, et al. Outcomes of ventricular tachycardia ablation using percutaneous left ventricular assist devices. Circ Arrhythm Electrophysiol. 2017;10(6):e004717. https:\/\/doi.org\/10.1161\/CIRCEP.116.004717.","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"1","key":"2249_CR11","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ccep.2016.10.011","volume":"9","author":"C Palaniswamy","year":"2017","unstructured":"Palaniswamy C, et al. Hemodynamic support for ventricular tachycardia ablation. Cardiac Electrophysiol Clin. 2017;9(1):141\u201352. https:\/\/doi.org\/10.1016\/j.ccep.2016.10.011.","journal-title":"Cardiac Electrophysiol Clin"},{"issue":"5","key":"2249_CR12","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.jacc.2023.05.012","volume":"82","author":"J Sroubek","year":"2023","unstructured":"Sroubek J, et al. First-in-human experience with Impella 5.0\/5.5 for high-risk patients with advanced heart failure undergoing VT ablation. J Am Coll Cardiol. 2023;82(5):469\u201371. https:\/\/doi.org\/10.1016\/j.jacc.2023.05.012.","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"2249_CR13","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1111\/jce.13312","volume":"28","author":"A Aryana","year":"2017","unstructured":"Aryana A, et al. Outcomes of catheter ablation of ventricular tachycardia with mechanical hemodynamic support: an analysis of the Medicare database. J Cardiovasc Electrophysiol. 2017;28(11):1295\u2013302. https:\/\/doi.org\/10.1111\/jce.13312.","journal-title":"J Cardiovasc Electrophysiol"},{"issue":"2","key":"2249_CR14","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1161\/CIRCEP.113.000548","volume":"7","author":"YM Reddy","year":"2014","unstructured":"Reddy YM, et al. Percutaneous left ventricular assist devices in ventricular tachycardia ablation: multicenter experience. Circ Arrhythm Electrophysiol. 2014;7(2):244\u201350. https:\/\/doi.org\/10.1161\/CIRCEP.113.000548.","journal-title":"Circ Arrhythm Electrophysiol"}],"container-title":["Journal of Interventional Cardiac Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10840-026-02249-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10840-026-02249-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10840-026-02249-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:54:55Z","timestamp":1792572895000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10840-026-02249-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":14,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["2249"],"URL":"https:\/\/doi.org\/10.1007\/s10840-026-02249-2","relation":{},"ISSN":["1572-8595"],"issn-type":[{"value":"1572-8595","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]},"assertion":[{"value":"25 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethical review and approval were waived for this study as it utilized the National Inpatient Sample (NIS) database, which contains de-identified patient information and publicly available. According to our institution\u2019s policy, studies using de-identified data are exempt from IRB review.","order":1,"name":"Ethics","label":"Ethical statement","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}