{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T07:21:47Z","timestamp":1794640907296,"version":"4.9.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Basel","id":[{"id":"https:\/\/ror.org\/02s6k3f65","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Interv Card Electrophysiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The impact of left atrial (LA) anatomical features on atrial arrhythmia (AA) recurrence after pulsed-field (PF)-based pulmonary vein isolation (PVI) is unknown. This study aimed to assess LA anatomical features associated with long-term AA recurrence after PVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively enrolled patients undergoing PVI with a pentaspline PF-catheter at a tertiary center from June 2023 to September 2024. AA recurrence was assessed at 3, 6 and 12 months with Holter-ECGs and symptom-driven monitoring. The following anatomical features were assessed in pre-interventional CT or MR imaging: pulmonary vein (PV) ostial diameters, circularity, cross-sectional area, and inter-carina distances. Regression models adjusted for established risk factors were used for their associations with AA recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 287 patients (median age 66 years; 34% female; 61% paroxysmal AF), 98 (34%) experienced recurrence at a median of 6 months after PVI. In adjusted regression analysis, a larger minimal diameter of the right superior PV (OR 1.11 per 1\u00a0mm increase, 95% CI (1.02\u20131.21);\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021), and higher circularity indices of the left inferior PV (OR 1.04 per 0.01 increase, 95% CI (1.01\u20131.07);\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) and the right superior PV (OR 1.03 per 0.01 increase, 95% CI (1.00\u20131.06);\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040) were associated with AA recurrence. There was no interaction for catheter size but some effect modification for the number of PF-applications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Specific anatomical features of the right superior and left inferior PV were associated with recurrence after PF-based PVI. Although PF-based PVI appears suitable across diverse LA anatomies, the prognostic value of these anatomical characteristics warrants further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10840-026-02435-2","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:15:22Z","timestamp":1789550122000},"page":"3137-3146","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Left atrial anatomy and atrial arrhythmia recurrence after pulsed-field ablation"],"prefix":"10.1007","volume":"69","author":[{"given":"Mikko","family":"Mutti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Spreen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Br\u00fcgger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Jordan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Schaerli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albin","family":"Bislimaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behnam","family":"Subin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Mahfoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Sticherling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"K\u00fchne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Badertscher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Knecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Krisai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"},{"role":"corresponding-author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"issue":"7","key":"2435_CR1","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1038\/s41591-024-03114-3","volume":"30","author":"E Ekanem","year":"2024","unstructured":"Ekanem E, Neuzil P, Reichlin T, Kautzner J, van der Voort P, Jais P, et al. 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Royalties from Springer Nature. Christian Sticherling: Member of Medtronic Advisory Board Europe and Boston Scientific Advisory Board Europe, received educational grants from Biosense Webster and Biotronik and a research grant from the European Union\u2019s FP7 program and Biosense Webster and lecture and consulting fees from Abbott, Medtronic, Biosense Webster, Boston Scientific, Microport, and Biotronik, all outside the submitted work. Philipp Krisai reports speaker fees from BMS\/Pfizer. Grants from the Swiss National Science Foundation, Swiss Heart Foundation, Foundation for Cardiovascular Research Basel, Machaon Foundation. Felix Mahfoud has been supported by Deutsche Gesellschaft f\u00fcr Kardiologie (DGK), Deutsche Forschungsgemeinschaft (SFB TRR219, Project-ID 322900939), and Deutsche Herzstiftung. Until May 2024, FM received speaker honoraria\/consulting fees from Ablative Solutions, Amgen, Astra-Zeneca, Bayer, Boehringer Ingelheim, Inari, Medtronic, Merck, ReCor Medical, Servier, and Terumo all outside the submitted work. Patrick Badertscher has received research funding from the \u201cUniversity of Basel\u201c, the \u201cStiftung f\u00fcr Herzschrittmacher und Elektrophysiologie\u201d, the \u201cFreiwillige Akademische Gesellschaft Basel\u201d, the \u201cSwiss Heart Foundation\u201d and Johnson&Johnson, and reports personal fees from BMS, Boston Scientific and Abbott, all outside the submitted work. Sven Knecht has received funding of the \u201cSwiss Heart Foundation\u201d outside of the submitted work. The other authors have nothing to declare.","order":2,"name":"Ethics","label":"Disclosures","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}