{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:40:51Z","timestamp":1786981251247,"version":"build-2736575974"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T00:00:00Z","timestamp":1648252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T00:00:00Z","timestamp":1648252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["2015-1\/257849"],"award-info":[{"award-number":["2015-1\/257849"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["2013-222290"],"award-info":[{"award-number":["2013-222290"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Bioenerg Biomembr"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s10863-022-09937-4","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T20:03:54Z","timestamp":1648497834000},"page":"145-152","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chronic exposure to ozone induces cardiac antioxidant response and overexpression of either mitochondrial fision protein DRP1 and hipertrophyc-related proteins"],"prefix":"10.1007","volume":"54","author":[{"given":"Nancy P.","family":"G\u00f3mez-Cris\u00f3stomo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selva","family":"Rivas-Arancibia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Rodr\u00edguez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erick N.","family":"De la Cruz-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coraz\u00f3n","family":"de Mar\u00eda M\u00e1rquez \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Alexis","family":"Estrada Caraveo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noem\u00ed","family":"Gelista Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlen","family":"Vald\u00e9s-Fuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6369-5880","authenticated-orcid":false,"given":"Eduardo","family":"Mart\u00ednez-Abundis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,26]]},"reference":[{"issue":"6","key":"9937_CR1","doi-asserted-by":"publisher","first-page":"e21620","DOI":"10.1096\/fj.202100067R","volume":"J35","author":"M Adebayo","year":"2021","unstructured":"Adebayo M, Singh S, Singh AP, Dasgupta S (2021) Mitochondrial fusion and fission: the fine-tune balance for cellular homeostasis. FASEB J35(6):e21620. https:\/\/doi.org\/10.1096\/fj.202100067R","journal-title":"FASEB"},{"issue":"20","key":"9937_CR2","doi-asserted-by":"publisher","first-page":"24815","DOI":"10.1007\/s11356-020-09042-2","volume":"27","author":"AA Almetwally","year":"2020","unstructured":"Almetwally AA, Bin-Jumah M, Allam AA (2020) Ambient air pollution and its influence on human health and welfare: an overview. Environ Sci Pollut Res Int 27(20):24815\u201324830","journal-title":"Environ Sci Pollut Res Int"},{"issue":"3","key":"9937_CR3","doi-asserted-by":"publisher","first-page":"825","DOI":"10.3233\/JAD-200289","volume":"76","author":"L Attademo","year":"2020","unstructured":"Attademo L, Bernardini F (2020) Air pollution as risk factor for mental disorders: In search for a possible link with Alzheimer's disease and schizophrenia. J Alzheimers Dis 76(3):825\u2013830","journal-title":"J Alzheimers Dis"},{"issue":"19","key":"9937_CR4","first-page":"30006","volume":"S0213-4853","author":"PC Bello-Medina","year":"2019","unstructured":"Bello-Medina PC, Rodr\u00edguez-Mart\u00ednez E, Prado-Alcal\u00e1 RA, Rivas-Arancibia S (2019) Ozone pollution, oxidative stress, synaptic plasticity, and neurodegeneration. Contaminaci\u00f3n por ozono, estr\u00e9s oxidativo, plasticidad sin\u00e1ptica y neurodegeneraci\u00f3n. Neurologia S0213-4853(19):30006\u201330004","journal-title":"Neurologia"},{"issue":"2","key":"9937_CR5","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1177\/0192623308329340","volume":"37","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2009","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Mac\u00edas-Parra M, Hoffmann HJ et al (2009) Immunotoxicity and environment: Immunodysregulation and systemic inflammation in children. Toxicol Pathol 37(2):161\u2013169","journal-title":"Toxicol Pathol"},{"key":"9937_CR6","doi-asserted-by":"publisher","unstructured":"Cheng QQ, Wan YW, Yang WM et al (2020) Gastrodin protects H9c2 cardiomyocytes against oxidative injury by ameliorating imbalanced mitochondrial dynamics and mitochondrial dysfunction. Acta Pharmacol Sin. https:\/\/doi.org\/10.1038\/s41401-020-0382-x","DOI":"10.1038\/s41401-020-0382-x"},{"issue":"3\u20134","key":"9937_CR7","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3109\/00207450108986511","volume":"108","author":"C Dorado-Mart\u00ednez","year":"2001","unstructured":"Dorado-Mart\u00ednez C, Paredes-Carbajal C, Mascher D, Borgonio-P\u00e9rez G, Rivas-Arancibia S (2001) Effects of different ozone doses on memory, motor activity and lipid peroxidation levels, in rats. Int J Neurosci 108(3\u20134):149\u2013161. https:\/\/doi.org\/10.3109\/00207450108986511","journal-title":"Int J Neurosci"},{"key":"9937_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cotox.2017.10.007","volume":"7","author":"TR Dugas","year":"2018","unstructured":"Dugas TR (2018) Unraveling mechanisms of toxicant-induced oxidative stress in cardiovascular disease. Curr Opin Toxicol 7:1\u20138. https:\/\/doi.org\/10.1016\/j.cotox.2017.10.007","journal-title":"Curr Opin Toxicol"},{"key":"9937_CR9","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/978-3-319-55330-6_11","volume":"982","author":"HDTF Facundo","year":"2017","unstructured":"Facundo HDTF, Brainard RE, Caldas FRL, Lucas AMB (2017) Mitochondria and cardiac hypertrophy. Adv Exp Med Biol 982:203\u2013226","journal-title":"Adv Exp Med Biol"},{"key":"9937_CR10","doi-asserted-by":"publisher","first-page":"805764","DOI":"10.1155\/2014\/805764","volume":"2014","author":"NP G\u00f3mez-Cris\u00f3stomo","year":"2014","unstructured":"G\u00f3mez-Cris\u00f3stomo NP, Rodr\u00edguez Mart\u00ednez E, Rivas-Arancibia S (2014) Oxidative stress activates the transcription factors FoxO 1a and FoxO 3a in the hippocampus of rats exposed to low doses of ozone. Oxidative Med Cell Longev 2014:805764. https:\/\/doi.org\/10.1155\/2014\/805764","journal-title":"Oxidative Med Cell Longev"},{"issue":"1","key":"9937_CR11","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1186\/s12906-016-1256-0","volume":"16","author":"S Jan","year":"2016","unstructured":"Jan S, Khan MR (2016) Protective effects of Monotheca buxifolia fruit on renal toxicity induced by CCl4 in rats. BMC Complement Altern Med 16(1):289. https:\/\/doi.org\/10.1186\/s12906-016-1256-0","journal-title":"BMC Complement Altern Med"},{"issue":"1","key":"9937_CR12","doi-asserted-by":"publisher","first-page":"11","DOI":"10.5483\/bmbrep.2008.41.1.011","volume":"41","author":"SY Jeong","year":"2008","unstructured":"Jeong SY, Seol DW (2008) The role of mitochondria in apoptosis. BMB Rep 41(1):11\u201322. https:\/\/doi.org\/10.5483\/bmbrep.2008.41.1.011","journal-title":"BMB Rep"},{"issue":"1\u20132","key":"9937_CR13","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s11010-018-3450-5","volume":"454","author":"CJ Jong","year":"2019","unstructured":"Jong CJ, Yeung J, Tseung E, Karmazyn M (2019) Leptin-induced cardiomyocyte hypertrophy is associated with enhanced mitochondrial fission. Mol Cell Biochem 454(1\u20132):33\u201344. https:\/\/doi.org\/10.1007\/s11010-018-3450-5","journal-title":"Mol Cell Biochem"},{"key":"9937_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1139\/bcb-2020-0641","volume":"23","author":"WC Li","year":"2021","unstructured":"Li WC, Yao SP, Zhang J, Liu WB, Liu J, Geng CK (2021) Low-dose lipopolysaccharide protects nerve cells against spinal cord injury via regulating the PI3K-AKT-Nrf2 signaling pathway. Biochem Cell Biol 23:1\u20139. https:\/\/doi.org\/10.1139\/bcb-2020-0641","journal-title":"Biochem Cell Biol"},{"key":"9937_CR15","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1001\/jama.2012.126","volume":"307","author":"H Mustafic","year":"2012","unstructured":"Mustafic H, Jabre P, Caussin C, Murad MH, Escolano S, Tafflet M, Perier MC, Marijon E, Vernerey D, Empana JP, Jouven X (2012) Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA 307:713\u2013721","journal-title":"JAMA"},{"issue":"7","key":"9937_CR16","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1016\/j.bbamcr.2017.03.006","volume":"1864","author":"J Nan","year":"2017","unstructured":"Nan J, Zhu W, Rahman MS, Liu M, Li D, Su S, Zhang N, Hu X, Yu H, Gupta MP, Wang J (2017) Molecular regulation of mitochondrial dynamics in cardiac disease. Biochim Biophys Acta, Mol Cell Res 1864(7):1260\u20131273. https:\/\/doi.org\/10.1016\/j.bbamcr.2017.03.006","journal-title":"Biochim Biophys Acta, Mol Cell Res"},{"issue":"9","key":"9937_CR17","doi-asserted-by":"publisher","first-page":"8074","DOI":"10.1007\/s11356-017-9239-3","volume":"25","author":"D Nuvolone","year":"2018","unstructured":"Nuvolone D, Petri D, Voller F (2018) The effects of ozone on human health. Environ Sci Pollut Res Int 25(9):8074\u20138088","journal-title":"Environ Sci Pollut Res Int"},{"issue":"Pt 12","key":"9937_CR18","doi-asserted-by":"publisher","first-page":"2659","DOI":"10.1242\/jcs.139394","volume":"127","author":"C Pennanen","year":"2014","unstructured":"Pennanen C, Parra V, L\u00f3pez-Crisosto C, Morales PE, Del Campo A, Gutierrez T, Rivera-Mej\u00edas P et al (2014) Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+\u2212calcineurin signaling pathway. J Cell Sci 127(Pt 12):2659\u20132671. https:\/\/doi.org\/10.1242\/jcs.139394","journal-title":"J Cell Sci"},{"issue":"1","key":"9937_CR19","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/0891-5849(91)90186-7","volume":"11","author":"WA Pryor","year":"1991","unstructured":"Pryor WA, Church DF (1991) Aldehydes, hydrogen peroxide, and organic radicals as mediators of ozone toxicity. Free Radic Biol Med 11(1):41\u201346. https:\/\/doi.org\/10.1016\/0891-5849(91)90186-7 Erratum in: Free Radic Biol Med 1992;12(5):451","journal-title":"Free Radic Biol Med"},{"key":"9937_CR20","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/0378-4274(95)03563-x","volume":"82-83","author":"WA Pryor","year":"1995","unstructured":"Pryor WA, Squadrito GL, Friedman M (1995) A new mechanism for the toxicity of ozone. Toxicol Lett 82-83:287\u2013293. https:\/\/doi.org\/10.1016\/0378-4274(95)03563-x","journal-title":"Toxicol Lett"},{"issue":"1","key":"9937_CR21","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1093\/toxsci\/kfp252","volume":"113","author":"S Rivas-Arancibia","year":"2010","unstructured":"Rivas-Arancibia S, Guevara-Guzm\u00e1n R, L\u00f3pez-Vidal Y et al (2010) Oxidative stress caused by ozone exposure induces loss of brain repair in the hippocampus of adult rats. Toxicol Sci 113(1):187\u2013197","journal-title":"Toxicol Sci"},{"issue":"2","key":"9937_CR22","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s11356-009-0140-6","volume":"17","author":"V Rubio","year":"2010","unstructured":"Rubio V, Valverde M, Rojas E (2010) Effects of atmospheric pollutants on the Nrf2 survival pathway. Environ Sci Pollut Res Int 17(2):369\u2013382. https:\/\/doi.org\/10.1007\/s11356-009-0140-6","journal-title":"Environ Sci Pollut Res Int"},{"key":"9937_CR23","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/978-3-319-55330-6_4","volume":"982","author":"FL Sheeran","year":"2017","unstructured":"Sheeran FL, Pepe S (2017) Mitochondrial bioenergetics and dysfunction in failing heart. Adv Exp Med Biol 982:65\u201380","journal-title":"Adv Exp Med Biol"},{"key":"9937_CR24","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1476-7120-7-30","volume":"7","author":"V Srebot","year":"2009","unstructured":"Srebot V, Gianicolo EA, Rainaldi G, Trivella MG, Sicari R (2009) Ozone and cardiovascular injury. Cardiovasc Ultrasound 7:30. https:\/\/doi.org\/10.1186\/1476-7120-7-30","journal-title":"Cardiovasc Ultrasound"},{"issue":"22","key":"9937_CR25","doi-asserted-by":"publisher","first-page":"2934","DOI":"10.1161\/01.CIR.99.22.2934","volume":"99","author":"R von Harsdorf","year":"1999","unstructured":"von Harsdorf R, Li PF, Dietz R (1999) Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation 99(22):2934\u20132941","journal-title":"Circulation"},{"issue":"5","key":"9937_CR26","doi-asserted-by":"publisher","first-page":"57001","DOI":"10.1289\/EHP3325","volume":"127","author":"M Wang","year":"2019","unstructured":"Wang M, Sampson PD, Sheppard LE, Stein JH, Vedal S, Kaufman JD (2019) Long-term exposure to ambient ozone and progression of subclinical arterial disease: the multi-ethnic study of atherosclerosis and air pollution. Environ Health Perspect 127(5):57001","journal-title":"Environ Health Perspect"},{"key":"9937_CR27","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.ijcard.2014.05.044","volume":"175","author":"WS Yang","year":"2014","unstructured":"Yang WS, Wang X, Deng Q, Fan WY, Wang WY (2014) An evidence-based appraisal of global association between air pollution and risk of stroke. Int J Cardiol 175:307\u2013313","journal-title":"Int J Cardiol"},{"key":"9937_CR28","doi-asserted-by":"publisher","first-page":"2518","DOI":"10.3389\/fimmu.2019.02518","volume":"10","author":"JJ Zhang","year":"2019","unstructured":"Zhang JJ, Wei Y, Fang Z (2019) Ozone pollution: a major health Hazard worldwide. Front Immunol 10:2518","journal-title":"Front Immunol"}],"updated-by":[{"DOI":"10.1007\/s10863-022-09943-6","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T00:00:00Z","timestamp":1656892800000}}],"container-title":["Journal of Bioenergetics and Biomembranes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10863-022-09937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10863-022-09937-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10863-022-09937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T03:25:51Z","timestamp":1657682751000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10863-022-09937-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,26]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["9937"],"URL":"https:\/\/doi.org\/10.1007\/s10863-022-09937-4","relation":{},"ISSN":["0145-479X","1573-6881"],"issn-type":[{"value":"0145-479X","type":"print"},{"value":"1573-6881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,26]]},"assertion":[{"value":"16 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2022","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10863-022-09943-6","URL":"https:\/\/doi.org\/10.1007\/s10863-022-09943-6","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report not conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}