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Antoni and F.J. Penedo are consultants for Blue Note Therapeutics. P.B. Pedreira, S.E. Fleszar-Pavlovi\u0107, E.A. Walsh, B. Noriega Esquives, P.I. Moreno, D. Perdomo, and A. Heller declare they have no financial or non-financial interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"Approval was obtained from the ethics committee of the University of Miami and Northwestern University. The procedures used in this study adhere to the tenets of the 1964 Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"This study was pre-registered at ClinicalTrials.gov on November 17, 2017 (NCT03344757). The analysis plan for this study was not formally pre-registered, and de-identified data from the study are not publicly archived. However, the de-identified data can be requested by emailing the corresponding author, in accordance with the University of Miami IRB standards. The analytic code used for the analyses presented in this study is not publicly available but may be obtained by contacting the corresponding author. Additionally, the materials used to conduct the study are not publicly available.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Transparency statements"}}]}}