{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T07:45:26Z","timestamp":1776930326834,"version":"3.51.2"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2009,2,14]],"date-time":"2009-02-14T00:00:00Z","timestamp":1234569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1007\/s10875-009-9277-9","type":"journal-article","created":{"date-parts":[[2009,2,13]],"date-time":"2009-02-13T09:25:41Z","timestamp":1234517141000},"page":"470-478","source":"Crossref","is-referenced-by-count":74,"title":["Plasma 1,25 Dihydroxy Vitamin D3 Level and Expression of Vitamin D Receptor and Cathelicidin in Pulmonary Tuberculosis"],"prefix":"10.1007","volume":"29","author":[{"given":"P.","family":"Selvaraj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Prabhu Anand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Harishankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Alagarasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,2,14]]},"reference":[{"key":"9277_CR1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1046\/j.1445-5994.2003.00344.x","volume":"33","author":"SA Skull","year":"2003","unstructured":"Skull SA, Ngeow JY, Biggs BA, Street A, Ebeling PR. Vitamin D deficiency is common and unrecognized among recently arrived adult immigrants from The Horn of Africa. Intern Med J 2003;33:47\u201351. doi: 10.1046\/j.1445-5994.2003.00344.x .","journal-title":"Intern Med J"},{"issue":"1","key":"9277_CR2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0033-3549(04)50110-3","volume":"117","author":"AR Lifson","year":"2002","unstructured":"Lifson AR, Thai D, O\u2019Fallon A, Mills WA, Hang K. Prevalence of tuberculosis, hepatitis B virus, and intestinal parasitic infections among refugees to Minnesota. Public Health Rep 2002;117(1):69\u201377.","journal-title":"Public Health Rep"},{"key":"9277_CR3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4269\/ajtmh.2003.69.115","volume":"69","author":"R Lopez-Velez","year":"2003","unstructured":"Lopez-Velez R, Huerga H, Turrientes MC. Infectious diseases in immigrants from the perspective of a tropical medicine referral unit. Am J Trop Med Hyg 2003;69:115\u201321.","journal-title":"Am J Trop Med Hyg"},{"key":"9277_CR4","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1136\/thx.2006.070060","volume":"62","author":"A Sita-Lumsden","year":"2007","unstructured":"Sita-Lumsden A, Lapthorn G, Swaminathan R, Milburn HJ. Reactivation of tuberculosis and vitamin D deficiency: the contribution of diet and exposure to sunlight. Thorax 2007;62:1003\u20137. doi: 10.1136\/thx.2006.070060 .","journal-title":"Thorax"},{"key":"9277_CR5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0041-3879(85)90035-2","volume":"66","author":"JM Grange","year":"1985","unstructured":"Grange JM, Davies PD, Brown RC, Woodhead JS, Kardjito T. A study of vitamin D levels in Indonesian patients with untreated pulmonary tuberculosis. Tubercle 1985;66:187\u201391. doi: 10.1016\/0041-3879(85)90035-2 .","journal-title":"Tubercle"},{"key":"9277_CR6","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0140-6736(99)02301-6","volume":"355","author":"RJ Wilkinson","year":"2000","unstructured":"Wilkinson RJ, Llewelyn M, Toossi Z, Patel P, Pasvol G, Lalvani A, et al. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet 2000;355:618\u201321. doi: 10.1016\/S0140-6736(99)02301-6 .","journal-title":"Lancet"},{"key":"9277_CR7","first-page":"13","volume":"24","author":"P Anderson","year":"2003","unstructured":"Anderson P, May B, Morris H. Vitamin d metabolism: new concepts and clinical implications. Clin Biochem Rev 2003;24:13\u201326.","journal-title":"Clin Biochem Rev"},{"key":"9277_CR8","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1126\/science.1123933","volume":"311","author":"PT Liu","year":"2006","unstructured":"Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770\u20133. doi: 10.1126\/science.1123933 .","journal-title":"Science"},{"key":"9277_CR9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1262-3636(07)70017-4","volume":"29","author":"MT Malecki","year":"2003","unstructured":"Malecki MT, Klupa T, Wolkow P, Bochenski J, Wanic K, Sieradzki J. Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population. Diabetes Metab 2003;29:119\u201324. doi: 10.1016\/S1262-3636(07)70017-4 .","journal-title":"Diabetes Metab"},{"key":"9277_CR10","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1677\/jme.1.01760","volume":"34","author":"CE Jennings","year":"2005","unstructured":"Jennings CE, Owen CJ, Wilson V, Pearce SH. A haplotype of the CYP27B1 promoter is associated with autoimmune Addison\u2019s disease but not with Graves\u2019 disease in a UK population. J Mol Endocrinol 2005;34:859\u201363. doi: 10.1677\/jme.1.01760 .","journal-title":"J Mol Endocrinol"},{"key":"9277_CR11","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1128\/IAI.00353-08","volume":"76","author":"JH White","year":"2008","unstructured":"White JH. Vitamin D signaling, infectious diseases and regulation of innate immunity. Infect Immun 2008;76:3837\u201343. doi: 10.1128\/IAI.00353-08 .","journal-title":"Infect Immun"},{"key":"9277_CR12","doi-asserted-by":"crossref","first-page":"7190","DOI":"10.4049\/jimmunol.178.11.7190","volume":"178","author":"AR Martineau","year":"2007","unstructured":"Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, et al. IFN-gamma- and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37. J Immunol 2007;178:7190\u20138.","journal-title":"J Immunol"},{"key":"9277_CR13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1023\/B:JOCI.0000025446.44146.52","volume":"24","author":"G Chandra","year":"2004","unstructured":"Chandra G, Selvaraj P, Jawahar MS, Banurekha VV, Narayanan PR. Effect of vitamin D3 on phagocytic potential of macrophages with live Mycobacterium tuberculosis and lymphoproliferative response in pulmonary tuberculosis. J Clin Immunol 2004;24:249\u201357. doi: 10.1023\/B:JOCI.0000025446.44146.52 .","journal-title":"J Clin Immunol"},{"key":"9277_CR14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.cyto.2007.08.005","volume":"40","author":"M Vidyarani","year":"2007","unstructured":"Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR. 1,25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine 2007;40:128\u201334. doi: 10.1016\/j.cyto.2007.08.005 .","journal-title":"Cytokine"},{"key":"9277_CR15","first-page":"3","volume":"38","author":"EW Nursyam","year":"2006","unstructured":"Nursyam EW, Amin Z, Rumende CM. The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion. Acta Med Indones 2006;38:3\u20135.","journal-title":"Acta Med Indones"},{"key":"9277_CR16","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.gene.2004.05.014","volume":"338","author":"AG Uitterlinden","year":"2004","unstructured":"Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA, Van Leeuwen JP. Genetics and biology of vitamin D receptor polymorphisms. Gene 2004;338:143\u201356. doi: 10.1016\/j.gene.2004.05.014 .","journal-title":"Gene"},{"key":"9277_CR17","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1023\/B:JOCI.0000040923.07879.31","volume":"24","author":"P Selvaraj","year":"2004","unstructured":"Selvaraj P, Chandra G, Jawahar MS, Rani MV, Rajeshwari DN, Narayanan PR. Regulatory role of vitamin D receptor gene variants of Bsm I, Apa I, Taq I, and Fok I polymorphisms on macrophage phagocytosis and lymphoproliferative response to Mycobacterium tuberculosis antigen in pulmonary tuberculosis. J Clin Immunol 2004;24:523\u201332. doi: 10.1023\/B:JOCI.0000040923.07879.31 .","journal-title":"J Clin Immunol"},{"key":"9277_CR18","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/s10875-007-9152-5","volume":"28","author":"P Selvaraj","year":"2008","unstructured":"Selvaraj P, Vidyarani M, Alagarasu K, Prabhu Anand S, Narayanan PR. Regulatory role of promoter and 3\u2032 UTR variants of vitamin D receptor gene on cytokine response in pulmonary tuberculosis. J Clin Immunol 2008;28:306\u201313. doi: 10.1007\/s10875-007-9152-5 .","journal-title":"J Clin Immunol"},{"key":"9277_CR19","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1359\/jbmr.2003.18.9.1632","volume":"18","author":"Y Fang","year":"2003","unstructured":"Fang Y, van Meurs JB, Bergink AP, Hofman A, van Duijn CM, van Leeuwen JP, et al. Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly. J Bone Miner Res 2003;18:1632\u201341. doi: 10.1359\/jbmr.2003.18.9.1632 .","journal-title":"J Bone Miner Res"},{"issue":"3","key":"9277_CR20","doi-asserted-by":"crossref","first-page":"504","DOI":"10.2337\/diabetes.49.3.504","volume":"49","author":"MA Pani","year":"2000","unstructured":"Pani MA, Knapp M, Donner H, Braun J, Baur MP, Usadel KH, et al. Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans. Diabetes 2000;49(3):504\u20137. doi: 10.2337\/diabetes.49.3.504 .","journal-title":"Diabetes"},{"key":"9277_CR21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/ije\/dym247","volume":"37","author":"KE Nnoaham","year":"2008","unstructured":"Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol 2008;37:113\u20139. doi: 10.1093\/ije\/dym247 .","journal-title":"Int J Epidemiol"},{"key":"9277_CR22","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.lab.2003.08.002","volume":"143","author":"JM Chang","year":"2004","unstructured":"Chang JM, Kuo MC, Kuo HT, Hwang SJ, Tsai JC, Chen HC, et al. 1-Alpha,25-Dihydroxyvitamin D3 regulates inducible nitric oxide synthase messenger RNA expression and nitric oxide release in macrophage-like RAW 264.7 cells. J Lab Clin Med 2004;143:14\u201322. doi: 10.1016\/j.lab.2003.08.002 .","journal-title":"J Lab Clin Med"},{"key":"9277_CR23","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/00063198-200009000-00010","volume":"6","author":"OP Sharma","year":"2000","unstructured":"Sharma OP. Hypercalcemia in granulomatous disorders: a clinical review. Curr Opin Pulm Med 2000;6:442\u20137. doi: 10.1097\/00063198-200009000-00010 .","journal-title":"Curr Opin Pulm Med"},{"issue":"1\u20132","key":"9277_CR24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.mce.2006.08.009","volume":"263","author":"D Lechner","year":"2007","unstructured":"Lechner D, Kallay E, Cross HS. 1Alpha,25-dihydroxyvitamin D3 downregulates CYP27B1 and induces CYP24A1 in colon cells. Mol Cell Endocrinol 2007;263(1\u20132):55\u201364. doi: 10.1016\/j.mce.2006.08.009 .","journal-title":"Mol Cell Endocrinol"},{"key":"9277_CR25","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1096\/fj.04-3284com","volume":"19","author":"FA Gombart","year":"2005","unstructured":"Gombart FA, Borregaard N, Koeffler P. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly upregulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J 2005;19:1067\u201377. doi: 10.1096\/fj.04-3284com .","journal-title":"FASEB J"},{"key":"9277_CR26","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0955-0674(95)80094-8","volume":"7","author":"CJ Decker","year":"1995","unstructured":"Decker CJ, Parker R. Diversity of cytoplasmic functions for the 3\u2032 untranslated region of eukaryotic transcripts. Curr Opin Cell Biol 1995;7:386\u201392. doi: 10.1016\/0955-0674(95)80094-8 .","journal-title":"Curr Opin Cell Biol"},{"key":"9277_CR27","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/367284a0","volume":"367","author":"NA Morrison","year":"1994","unstructured":"Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, et al. Prediction of bone density from vitamin D receptor alleles. Nature 1994;367:284\u20137. doi: 10.1038\/367284a0 .","journal-title":"Nature"},{"key":"9277_CR28","first-page":"2255","volume":"83","author":"T Carling","year":"1998","unstructured":"Carling T, Rastad J, Akerstrom G, Westin G. Vitamin D receptor (VDR) and parathyroid hormone messenger ribonucleic acid levels correspond to polymorphic VDR alleles in human parathyroid tumors. J Clin Endocrinol Metab 1998;83:2255\u20139. doi: 10.1210\/jc.83.7.2255 .","journal-title":"J Clin Endocrinol Metab"},{"key":"9277_CR29","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.2337\/diabetes.51.7.2294","volume":"51","author":"BW Ogunkolade","year":"2002","unstructured":"Ogunkolade BW, Boucher BJ, Prahl JM, Bustin SA, Burrin JM, Noonan K, et al. Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians. Diabetes 2002;51:2294\u2013300. doi: 10.2337\/diabetes.51.7.2294 .","journal-title":"Diabetes"},{"key":"9277_CR30","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s007740050080","volume":"17","author":"M Yamagata","year":"1999","unstructured":"Yamagata M, Nakajima S, Tokita A, Sakai N, Yanagihara I, Yabuta K, et al. Analysis of the stable levels of messenger RNA derived from different polymorphic alleles in the vitamin D receptor gene. J Bone Miner Metab 1999;17:164\u201370. doi: 10.1007\/s007740050080 .","journal-title":"J Bone Miner Metab"},{"key":"9277_CR31","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1086\/497438","volume":"77","author":"Y Fang","year":"2005","unstructured":"Fang Y, van Meurs JB, d\u2019Alesio A, Jhamai M, Zhao H, Rivadeneira F, et al. Promoter and 3\u2032-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the Rotterdam study. Am J Hum Genet 2005;77:807\u201323. doi: 10.1086\/497438 .","journal-title":"Am J Hum Genet"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-009-9277-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10875-009-9277-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-009-9277-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T04:10:05Z","timestamp":1559275805000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10875-009-9277-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,14]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["9277"],"URL":"https:\/\/doi.org\/10.1007\/s10875-009-9277-9","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"value":"0271-9142","type":"print"},{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,14]]}}}