{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T16:11:45Z","timestamp":1787155905168,"version":"build-2736575974"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,4,18]],"date-time":"2016-04-18T00:00:00Z","timestamp":1460937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1007\/s10875-016-0278-1","type":"journal-article","created":{"date-parts":[[2016,4,18]],"date-time":"2016-04-18T04:50:56Z","timestamp":1460955056000},"page":"511-516","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["The Potential and Limits of Hematopoietic Stem Cell Transplantation for the Treatment of Autosomal Dominant Hyper-IgE Syndrome"],"prefix":"10.1007","volume":"36","author":[{"given":"Masakatsu","family":"Yanagimachi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ohya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Yokosuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Kajiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehiro","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Morio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumpei","family":"Yokota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,18]]},"reference":[{"key":"278_CR1","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1038\/nature06096","volume":"448","author":"Y Minegishi","year":"2007","unstructured":"Minegishi Y, Saito M, Tsuchiya S, Tsuge I, Takada H, Hara T, et al. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007;448:1058\u201362.","journal-title":"Nature"},{"key":"278_CR2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/MOH.0000000000000104","volume":"22","author":"S Farmand","year":"2015","unstructured":"Farmand S, Sundin M. Hyper-IgE syndromes: recent advances in pathogenesis, diagnostics and clinical care. Curr Opin Hematol. 2015;22:12\u201322.","journal-title":"Curr Opin Hematol"},{"key":"278_CR3","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.jaci.2006.12.666","volume":"119","author":"AF Freeman","year":"2007","unstructured":"Freeman AF, Kleiner DE, Nadiminti H, Davis J, Quezado M, Anderson V, et al. Causes of death in hyper-IgE syndrome. J Allergy Clin Immunol. 2007;119:1234\u201340.","journal-title":"J Allergy Clin Immunol"},{"key":"278_CR4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/MOH.0b013e328365a13b","volume":"20","author":"AJ Worth","year":"2013","unstructured":"Worth AJ, Booth C, Veys P. Stem cell transplantation for primary immune deficiency. Curr Opin Hematol. 2013;20:501\u20138.","journal-title":"Curr Opin Hematol"},{"key":"278_CR5","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/sj.bmt.1702446","volume":"25","author":"AR Gennery","year":"2000","unstructured":"Gennery AR, Flood TJ, Abinun M, Cant AJ. Bone marrow transplantation does not correct the hyper IgE syndrome. Bone Marrow Transplant. 2000;25:1303\u20135.","journal-title":"Bone Marrow Transplant"},{"key":"278_CR6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jaci.2010.05.005","volume":"126","author":"E Goussetis","year":"2010","unstructured":"Goussetis E, Peristeri I, Kitra V, Traeger-Synodinos J, Theodosaki M, Psarra K, et al. Successful long-term immunologic reconstitution by allogeneic hematopoietic stem cell transplantation cures patients with autosomal dominant hyper-IgE syndrome. J Allergy Clin Immunol. 2010;126:392\u20134.","journal-title":"J Allergy Clin Immunol"},{"key":"278_CR7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0002-9343(98)00200-9","volume":"105","author":"TA Nester","year":"1998","unstructured":"Nester TA, Wagnon AH, Reilly WF, Spitzer G, Kjeldsberg CR, Hill HR. Effects of allogeneic peripheral stem cell transplantation in a patient with job syndrome of hyperimmunoglobulinemia E and recurrent infections. Am J Med. 1998;105:162\u20134.","journal-title":"Am J Med"},{"key":"278_CR8","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s10875-015-0167-z","volume":"35","author":"NC Patel","year":"2015","unstructured":"Patel NC, Gallagher JL, Torgerson TR, Gilman AL. Successful haploidentical donor hematopoietic stem cell transplant and restoration of STAT3 function in an adolescent with autosomal dominant hyper-IgE syndrome. J Clin Immunol. 2015;35:479\u201385.","journal-title":"J Clin Immunol"},{"key":"278_CR9","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.1182\/blood-2013-09-523167","volume":"123","author":"SM Steward-Tharp","year":"2014","unstructured":"Steward-Tharp SM, Laurence A, Kanno Y, Kotlyar A, Villarino AV, Sciume G, et al. A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3. Blood. 2014;123:2978\u201387.","journal-title":"Blood"},{"key":"278_CR10","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/sji.12063","volume":"78","author":"LY Zhang","year":"2013","unstructured":"Zhang LY, Tian W, Shu L, Jiang LP, Zhan YZ, Liu W, et al. Clinical features, STAT3 gene mutations and Th17 cell analysis in nine children with hyper-IgE syndrome in mainland China. Scand J Immunol. 2013;78:258\u201365.","journal-title":"Scand J Immunol"},{"key":"278_CR11","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1084\/jem.20120260","volume":"210","author":"SM Choi","year":"2013","unstructured":"Choi SM, McAleer JP, Zheng M, Pociask DA, Kaplan MH, Qin S, et al. Innate Stat3-mediated induction of the antimicrobial protein Reg3gamma is required for host defense against MRSA pneumonia. J Exp Med. 2013;210:551\u201361.","journal-title":"J Exp Med"},{"key":"278_CR12","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1172\/JCI40891","volume":"120","author":"JS Cho","year":"2010","unstructured":"Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest. 2010;120:1762\u201373.","journal-title":"J Clin Invest"},{"key":"278_CR13","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/MD.0b013e31825f95b9","volume":"91","author":"MO Chandesris","year":"2012","unstructured":"Chandesris MO, Melki I, Natividad A, Puel A, Fieschi C, Yun L, et al. Autosomal dominant STAT3 deficiency and hyper-IgE syndrome: molecular, cellular, and clinical features from a French national survey. Medicine (Baltimore). 2012;91:e1\u201319.","journal-title":"Medicine (Baltimore)"},{"key":"278_CR14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10875-014-9988-4","volume":"34","author":"O Wolach","year":"2014","unstructured":"Wolach O, Kuijpers T, Ben-Ari J, Gavrieli R, Feinstein-Goren N, Alders M, et al. Variable clinical expressivity of STAT3 mutation in hyperimmunoglobulin E syndrome: genetic and clinical studies of six patients. J Clin Immunol. 2014;34:163\u201370.","journal-title":"J Clin Immunol"},{"key":"278_CR15","doi-asserted-by":"crossref","first-page":"4367","DOI":"10.1182\/blood-2010-10-312082","volume":"117","author":"MA Slatter","year":"2011","unstructured":"Slatter MA, Rao K, Amrolia P, Flood T, Abinun M, Hambleton S, et al. Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience. Blood. 2011;117:4367\u201375.","journal-title":"Blood"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-016-0278-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10875-016-0278-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-016-0278-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T04:15:02Z","timestamp":1559276102000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10875-016-0278-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,18]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["278"],"URL":"https:\/\/doi.org\/10.1007\/s10875-016-0278-1","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"value":"0271-9142","type":"print"},{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,18]]}}}