{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:41:21Z","timestamp":1740123681095,"version":"3.37.3"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"crossref","award":["2011\/06136-6"],"award-info":[{"award-number":["2011\/06136-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s10875-018-0531-x","type":"journal-article","created":{"date-parts":[[2018,7,14]],"date-time":"2018-07-14T01:36:24Z","timestamp":1531532184000},"page":"628-634","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Low Rates of Poliovirus Antibodies in Primary Immunodeficiency Patients on Regular Intravenous Immunoglobulin Treatment"],"prefix":"10.1007","volume":"38","author":[{"given":"Beatriz T.","family":"Costa-Carvalho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen E.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia M.","family":"Fontes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Aim\u00e9-Nobre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela G. S.","family":"Gonzales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaine S.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celso","family":"Granato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Isabel","family":"de Moraes-Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,7,14]]},"reference":[{"key":"531_CR1","unstructured":"Polio Global Eradication Initiative, 2018. http:\/\/polioeradication.org\/polio-today\/polio-now\/"},{"key":"531_CR2","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1001\/jama.1987.03390100073029","volume":"257","author":"BM Nkowane","year":"1987","unstructured":"Nkowane BM, Wassilak SG, Orenstein WA, Bart KJ, Schonberger LB, Hinman AR, et al. Vaccine-associated paralytic poliomyelitis. United States: 1973 through 1984. JAMA. 1987;257:1335\u201340.","journal-title":"JAMA"},{"key":"531_CR3","doi-asserted-by":"publisher","first-page":"292","DOI":"10.3109\/08820139.2013.859156","volume":"43","author":"M Shaghaghi","year":"2014","unstructured":"Shaghaghi M, Parvaneh N, Ostad-Rahimi P, Fathi SM, Shahmahmoodi S, Abolhassani H, et al. Combined immunodeficiency presenting with vaccine-associated paralytic poliomyelitis: a case report and narrative review of literature. Immunol Investig. 2014;43:292\u20138.","journal-title":"Immunol Investig"},{"key":"531_CR4","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.3201\/eid1607.091606","volume":"16","author":"S Shahmahmoodi","year":"2010","unstructured":"Shahmahmoodi S, Mamishi S, Aghamohammadi A, Aghazadeh N, Tabatabaie H, Gooya MM, et al. Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995\u20132008. Emerg Infect Dis. 2010;16:1133\u20136.","journal-title":"Emerg Infect Dis"},{"key":"531_CR5","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.virusres.2008.07.006","volume":"137","author":"S Shahmahmoodi","year":"2008","unstructured":"Shahmahmoodi S, Parvaneh N, Burns C, Asghar H, Mamishi S, Tabatabaie H, et al. Isolation of a type 3 vaccine-derived poliovirus (VDPV) from an Iranian child with X-linked agammaglobulinemia. Virus Res. 2008;137:168\u201372.","journal-title":"Virus Res"},{"key":"531_CR6","first-page":"570","volume":"22","author":"S Hidalgo","year":"2003","unstructured":"Hidalgo S, Garcia Erro M, Cisterna D, Freire MC. Paralytic poliomyelitis caused by a vaccine-derived polio virus in an antibody-deficient Argentinean child. Pediatr Infect Dis J. 2003;22:570\u20132.","journal-title":"Pediatr Infect Dis J"},{"key":"531_CR7","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1016\/j.vaccine.2015.01.018","volume":"33","author":"J Guo","year":"2015","unstructured":"Guo J, Bolivar-Wagers S, Srinivas N, Holubar M, Maldonado Y. Immunodeficiency-related vaccine-derived poliovirus (iVDPV) cases: a systematic review and implications for polio eradication. Vaccine. 2015;33:1235\u201342.","journal-title":"Vaccine"},{"key":"531_CR8","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1093\/infdis\/128.6.802","volume":"128","author":"HV Wyatt","year":"1973","unstructured":"Wyatt HV. Poliomyelitis in hypogammaglobulinemics. J Infect Dis. 1973;128:802\u20136.","journal-title":"J Infect Dis"},{"key":"531_CR9","doi-asserted-by":"publisher","first-page":"20120140","DOI":"10.1098\/rstb.2012.0140","volume":"368","author":"NC Grassly","year":"2013","unstructured":"Grassly NC. The final stages of the global eradication of poliomyelitis. Philos Trans R Soc Lond Ser B Biol Sci. 2013;368:20120140.","journal-title":"Philos Trans R Soc Lond Ser B Biol Sci"},{"key":"531_CR10","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1128\/CMR.00001-09","volume":"22","author":"AJ Fried","year":"2009","unstructured":"Fried AJ, Bonilla FA. Pathogenesis, diagnosis, and management of primary antibody deficiencies and infections. Clin Microbiol Rev. 2009;22:396\u2013414.","journal-title":"Clin Microbiol Rev"},{"key":"531_CR11","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.jaip.2015.12.015","volume":"4","author":"D Bearden","year":"2016","unstructured":"Bearden D, Collett M, Quan PL, Costa-Carvalho BT, Sullivan KE. Enteroviruses in X-linked Agammaglobulinemia: update on epidemiology and therapy. J Allergy Clin Immunol Pract. 2016;4:1059\u201365.","journal-title":"J Allergy Clin Immunol Pract"},{"key":"531_CR12","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1128\/JCM.36.10.2893-2899.1998","volume":"36","author":"OM Kew","year":"1998","unstructured":"Kew OM, Sutter RW, Nottay BK, McDonough MJ, Prevots DR, Quick L, et al. Prolonged replication of a type 1 vaccine-derived poliovirus in an immunodeficient patient. J Clin Microbiol. 1998;36:2893\u20139.","journal-title":"J Clin Microbiol"},{"key":"531_CR13","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1086\/379791","volume":"188","author":"N Khetsuriani","year":"2003","unstructured":"Khetsuriani N, Prevots DR, Quick L, Elder ME, Pallansch M, Kew O, et al. Persistence of vaccine-derived polioviruses among immunodeficient persons with vaccine-associated paralytic poliomyelitis. J Infect Dis. 2003;188:1845\u201352.","journal-title":"J Infect Dis"},{"key":"531_CR14","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.biologicals.2006.02.005","volume":"34","author":"J Martin","year":"2006","unstructured":"Martin J. Vaccine-derived poliovirus from long term excretors and the end game of polio eradication. Biologicals. 2006;34:117\u201322.","journal-title":"Biologicals"},{"key":"531_CR15","doi-asserted-by":"publisher","first-page":"e1005114","DOI":"10.1371\/journal.ppat.1005114","volume":"11","author":"G Dunn","year":"2015","unstructured":"Dunn G, Klapsa D, Wilton T, Stone L, Minor PD, Martin J. Twenty-eight years of poliovirus replication in an immunodeficient individual: impact on the global polio eradication initiative. PLoS Pathog. 2015;11:e1005114.","journal-title":"PLoS Pathog"},{"key":"531_CR16","doi-asserted-by":"publisher","first-page":"7561","DOI":"10.1016\/j.vaccine.2012.10.035","volume":"30","author":"R Silva de","year":"2012","unstructured":"de Silva R, Gunasena S, Ratnayake D, Wickremesinghe GD, Kumarasiri CD, Pushpakumara BA, et al. Prevalence of prolonged and chronic poliovirus excretion among persons with primary immune deficiency disorders in Sri Lanka. Vaccine. 2012;30:7561\u20135.","journal-title":"Vaccine"},{"key":"531_CR17","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.intimp.2005.11.003","volume":"6","author":"EW Gelfand","year":"2006","unstructured":"Gelfand EW. Differences between IGIV products: impact on clinical outcome. Int Immunopharmacol. 2006;6:592\u20139.","journal-title":"Int Immunopharmacol"},{"issue":"Suppl 2","key":"531_CR18","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1365-2249.2011.04387.x","volume":"164","author":"SV Kaveri","year":"2011","unstructured":"Kaveri SV, Maddur MS, Hegde P, Lacroix-Desmazes S, Bayry J. Intravenous immunoglobulins in immunodeficiencies: more than mere replacement therapy. Clin Exp Immunol. 2011;164(Suppl 2):2\u20135.","journal-title":"Clin Exp Immunol"},{"key":"531_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1471-2172-15-26","volume":"15","author":"FA Nobre","year":"2014","unstructured":"Nobre FA, Gonzalez IG, Simao RM, de Moraes Pinto MI, Costa-Carvalho BT. Antibody levels to tetanus, diphtheria, measles and varicella in patients with primary immunodeficiency undergoing intravenous immunoglobulin therapy: a prospective study. BMC Immunol. 2014;15:26.","journal-title":"BMC Immunol"},{"key":"531_CR20","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.aller.2016.04.014","volume":"45","author":"RM Simao-Gurge","year":"2017","unstructured":"Simao-Gurge RM, Costa-Carvalho BT, Nobre FA, Gonzalez IG, de Moraes-Pinto MI. Prospective evaluation of Streptococcus pneumoniae serum antibodies in patients with primary immunodeficiency on regular intravenous immunoglobulin treatment. Allergol Immunopathol (Madr). 2017;45:55\u201362.","journal-title":"Allergol Immunopathol (Madr)"},{"key":"531_CR21","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.1749-6632.1995.tb44462.x","volume":"754","author":"RW Sutter","year":"1995","unstructured":"Sutter RW, Pallansch MA, Sawyer LA, Cochi SL, Hadler SC. Defining surrogate serologic tests with respect to predicting protective vaccine efficacy: poliovirus vaccination. Ann N Y Acad Sci. 1995;754:289\u201399.","journal-title":"Ann N Y Acad Sci"},{"key":"531_CR22","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.clim.2010.06.012","volume":"137","author":"JS Orange","year":"2010","unstructured":"Orange JS, Grossman WJ, Navickis RJ, Wilkes MM. Impact of trough IgG on pneumonia incidence in primary immunodeficiency: a meta-analysis of clinical studies. Clin Immunol. 2010;137:21\u201330.","journal-title":"Clin Immunol"},{"key":"531_CR23","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/S0022-3476(99)70246-5","volume":"134","author":"P Quartier","year":"1999","unstructured":"Quartier P, Debre M, De Blic J, de Sauverzac R, Sayegh N, Jabado N, et al. Early and prolonged intravenous immunoglobulin replacement therapy in childhood agammaglobulinemia: a retrospective survey of 31 patients. J Pediatr. 1999;134:589\u201396.","journal-title":"J Pediatr"},{"key":"531_CR24","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/j.1423-0410.1983.tb04485.x","volume":"44","author":"GW Fischer","year":"1983","unstructured":"Fischer GW, Hunter KW, Hemming VG, Wilson SR. Functional antibacterial activity of a human intravenous immunoglobulin preparation: in vitro and in vivo studies. Vox Sang. 1983;44:296\u20139.","journal-title":"Vox Sang"},{"key":"531_CR25","doi-asserted-by":"publisher","first-page":"S92","DOI":"10.1016\/0090-1229(92)90047-R","volume":"62","author":"GW Fischer","year":"1992","unstructured":"Fischer GW, Weisman LE, Hemming VG. Directed immune globulin for the prevention or treatment of neonatal group B streptococcal infections: a review. Clin Immunol Immunopathol. 1992;62:S92\u20137.","journal-title":"Clin Immunol Immunopathol"},{"key":"531_CR26","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1086\/519392","volume":"196","author":"CB Planitzer","year":"2007","unstructured":"Planitzer CB, Modrof J, Kreil TR. West Nile virus neutralization by US plasma-derived immunoglobulin products. J Infect Dis. 2007;196:435\u201340.","journal-title":"J Infect Dis"},{"key":"531_CR27","doi-asserted-by":"crossref","unstructured":"Orange JS, Du W, Falsey AR. Therapeutic immunoglobulin selected for high antibody titer to RSV also contains high antibody titers to other respiratory viruses. Front Immunol. 2015;6(431)","DOI":"10.3389\/fimmu.2015.00431"},{"key":"531_CR28","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.ebiom.2017.04.010","volume":"19","author":"S Rockman","year":"2017","unstructured":"Rockman S, Lowther S, Camuglia S, Vandenberg K, Taylor S, Fabri L, et al. Intravenous immunoglobulin protects against severe pandemic influenza infection. EBioMedicine. 2017;19:119\u201327.","journal-title":"EBioMedicine"},{"key":"531_CR29","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1086\/528993","volume":"197","author":"I Davidkin","year":"2008","unstructured":"Davidkin I, Jokinen S, Broman M, Leinikki P, Peltola H. Persistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up. J Infect Dis. 2008;197:950\u20136.","journal-title":"J Infect Dis"},{"key":"531_CR30","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1086\/381439","volume":"38","author":"U Heininger","year":"2004","unstructured":"Heininger U, Cherry JD, Stehr K. Serologic response and antibody-titer decay in adults with pertussis. Clin Infect Dis. 2004;38:591\u20134.","journal-title":"Clin Infect Dis"},{"key":"531_CR31","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1139\/w06-026","volume":"52","author":"DN Pavlov","year":"2006","unstructured":"Pavlov DN. Poliovirus vaccine strains in sewage and river water in South Africa. Can J Microbiol. 2006;52:717\u201323.","journal-title":"Can J Microbiol"},{"key":"531_CR32","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1084\/jem.71.6.765","volume":"71","author":"JR Paul","year":"1940","unstructured":"Paul JR, Trask JD, Gard S. II. Poliomyelitic virus in urban sewage. J Exp Med. 1940;71:765\u201377.","journal-title":"J Exp Med"},{"key":"531_CR33","first-page":"1393","volume":"59","author":"Centers for Disease C, and Prevention","year":"2010","unstructured":"Centers for Disease C, and Prevention. Outbreaks following wild poliovirus importations\u2014Europe, Africa, and Asia, January 2009\u2013September 2010. MMWR Morb Mortal Wkly Rep. 2010;59:1393\u20139.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"531_CR34","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1007\/s10875-017-0426-2","volume":"37","author":"KE Sullivan","year":"2017","unstructured":"Sullivan KE, Bassiri H, Bousfiha AA, Costa-Carvalho BT, Freeman AF, Hagin D, et al. Emerging infections and pertinent infections related to travel for patients with primary immunodeficiencies. J Clin Immunol. 2017;37:650\u201392.","journal-title":"J Clin Immunol"},{"key":"531_CR35","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1089\/hs.2016.0054","volume":"14","author":"M Doganay","year":"2016","unstructured":"Doganay M, Demiraslan H. Refugees of the Syrian civil war: impact on reemerging infections, health services, and biosecurity in Turkey. Health Secur. 2016;14:220\u20135.","journal-title":"Health Secur"},{"key":"531_CR36","first-page":"846","volume":"60","author":"Centers for Disease C, and Prevention","year":"2011","unstructured":"Centers for Disease C, and Prevention. Update on vaccine-derived polioviruses\u2014worldwide, July 2009\u2013March 2011. MMWR Morb Mortal Wkly Rep. 2011;60:846\u201350.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"531_CR37","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.clim.2003.11.011","volume":"111","author":"L Fiore","year":"2004","unstructured":"Fiore L, Plebani A, Buttinelli G, Fiore S, Donati V, Marturano J, et al. Search for poliovirus long-term excretors among patients affected by agammaglobulinemia. Clin Immunol. 2004;111:98\u2013102.","journal-title":"Clin Immunol"},{"key":"531_CR38","doi-asserted-by":"publisher","first-page":"881","DOI":"10.3855\/jidc.2372","volume":"6","author":"NM Galal","year":"2012","unstructured":"Galal NM, Bassiouny L, Nasr E, Abdelmeguid N. Isolation of poliovirus shedding following vaccination in children with antibody deficiency disorders. J Infect Dev Ctries. 2012;6:881\u20135.","journal-title":"J Infect Dev Ctries"},{"key":"531_CR39","first-page":"3","volume":"82","author":"NA Halsey","year":"2004","unstructured":"Halsey NA, Pinto J, Espinosa-Rosales F, Faure-Fontenla MA, da Silva E, Khan AJ, et al. Search for poliovirus carriers among people with primary immune deficiency diseases in the United States, Mexico, Brazil, and the United Kingdom. Bull World Health Organ. 2004;82:3\u20138.","journal-title":"Bull World Health Organ"},{"key":"531_CR40","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1111\/risa.12044","volume":"33","author":"RJ Duintjer Tebbens","year":"2013","unstructured":"Duintjer Tebbens RJ, Pallansch MA, Kalkowska DA, Wassilak SG, Cochi SL, Thompson KM. Characterizing poliovirus transmission and evolution: insights from modeling experiences with wild and vaccine-related polioviruses. Risk Anal. 2013;33:703\u201349.","journal-title":"Risk Anal"},{"key":"531_CR41","doi-asserted-by":"crossref","unstructured":"Aghamohammadi A, Abolhassani H, Kutukculer N, Wassilak SG, Pallansch MA, Kluglein S, et al. Patients with primary immunodeficiencies are a reservoir of poliovirus and a risk to polio eradication. Front Immunol. 2017;8(685)","DOI":"10.3389\/fimmu.2017.00685"},{"issue":"Suppl 1","key":"531_CR42","doi-asserted-by":"publisher","first-page":"S143","DOI":"10.1093\/infdis\/jit588","volume":"210","author":"CM Domingues","year":"2014","unstructured":"Domingues CM, de Fatima Pereira S, Cunha Marreiros AC, Menezes N, Flannery B. Introduction of sequential inactivated polio vaccine-oral polio vaccine schedule for routine infant immunization in Brazil\u2019s National Immunization Program. J Infect Dis. 2014;210(Suppl 1):S143\u201351.","journal-title":"J Infect Dis"},{"key":"531_CR43","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1046\/j.1469-0691.2000.00173.x","volume":"6","author":"JM Galama","year":"2000","unstructured":"Galama JM, Gielen M, Weemaes CM. Enterovirus antibody titers after IVIG replacement in agammaglobulinemic children. Clin Microbiol Infect. 2000;6:630\u20132.","journal-title":"Clin Microbiol Infect"},{"key":"531_CR44","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1590\/S0036-46652015000500017","volume":"57","author":"FA Nobre","year":"2015","unstructured":"Nobre FA, Gonzalez IG, de Moraes-Pinto MI, Costa-Carvalho BT. Protective levels of varicella-zoster antibody did not effectively prevent chickenpox in an X-linked agammaglobulinemia patient. Rev Inst Med Trop Sao Paulo. 2015;57:455\u20137.","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"531_CR45","doi-asserted-by":"publisher","first-page":"4437","DOI":"10.1016\/j.vaccine.2016.06.079","volume":"34","author":"E Ng","year":"2016","unstructured":"Ng E, Sanmartin C, Elien-Massenat D, Manuel DG. Vaccine-preventable disease-related hospitalization among immigrants and refugees to Canada: study of linked population-based databases. Vaccine. 2016;34:4437\u201342.","journal-title":"Vaccine"},{"key":"531_CR46","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1056\/NEJMp1406250","volume":"371","author":"E Kopel","year":"2014","unstructured":"Kopel E, Kaliner E, Grotto I. Lessons from a public health emergency\u2014importation of wild poliovirus to Israel. N Engl J Med. 2014;371:981\u20133.","journal-title":"N Engl J Med"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10875-018-0531-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-018-0531-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-018-0531-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T22:36:44Z","timestamp":1604615804000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10875-018-0531-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["531"],"URL":"https:\/\/doi.org\/10.1007\/s10875-018-0531-x","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"type":"print","value":"0271-9142"},{"type":"electronic","value":"1573-2592"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"13 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}