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Informed consent was obtained and all data appropriately de-identified. Three other patients were enrolled in an IRB-approved protocol at the University of South Florida and Johns Hopkins All Children\u2019s Hospital (USF) that allowed collection of data on patients with WHIM syndrome from collaborating sites. NIH and USF contributed this de-identified data for joint analysis and publication.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"J.E.W. has received grants as principal investigator on investigator-initiated translational studies and sponsored clinical trials of patients with WHIM syndrome funded by X4 Pharmaceuticals.Unrelated:J.E.W. has been an advisory board member, speaker bureau participant and site-principal investigator for a trial funded by Takeda (former Shire) outside of the submitted work.J.E.W. has also run sponsored studies for Lediant, Octapharma, and Momenta as site principal investigator outside of the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Freely-given, informed consent to participate in the study was obtained from parent or legal guardians for each infant.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Consent from individuals to publish de-identified data was included in NIH and USF enrollment consents.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The views expressed in this article are those of the author and do not reflect the official policy or position of the Department of the Army, DOD, or the U.S. Government.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}}]}}