{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:43:47Z","timestamp":1792197827813,"version":"4.4.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:00:00Z","timestamp":1772236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"DOI":"10.1007\/s10875-026-01985-4","type":"journal-article","created":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T12:04:47Z","timestamp":1772280287000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Porto-sinusoidal Vascular Disease is Associated with Gastrointestinal Disorders in Common Variable Immunodefiency"],"prefix":"10.1007","volume":"46","author":[{"given":"Emilie","family":"Corvilain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"G\u00e9rard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehane","family":"Fadlallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Galicier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Delaval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessy","family":"Alchidiac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Plessier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Boutboul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Fieschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Oksenhendler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre Emmanuel","family":"Rautou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Malphettes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,28]]},"reference":[{"key":"1985_CR1","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1086\/587669","volume":"46","author":"E Oksenhendler","year":"2008","unstructured":"Oksenhendler E, G\u00e9rard L, Fieschi C, Malphettes M, Mouillot G, Jaussaud R, et al. Infections in 252 Patients with Common Variable Immunodeficiency. Clin Infect Dis. 2008;46:1547\u201354.","journal-title":"Clin Infect Dis"},{"key":"1985_CR2","doi-asserted-by":"crossref","unstructured":"Dion J, Malphettes M, B\u00e9n\u00e9jat L, Megraud F, Wargnier A, Boutboul D et al. Campylobacter infection in adult patients with primary antibody deficiency. J Allergy Clin Immunol Pract. 2019;7:1038-1041.e4.","DOI":"10.1016\/j.jaip.2018.06.014"},{"issue":"1","key":"1985_CR3","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.diagmicrobio.2018.08.002","volume":"93","author":"MC Rolfes","year":"2019","unstructured":"Rolfes MC, Sriaroon P, D\u00e1vila Salda\u00f1a BJ, Dvorak CC, Chapdelaine H, Ferdman RM, Chen K, Jolles S, Patel NC, Kim YJ, Tarrant TK, Martelius T, Seppanen MJA. Chronic norovirus infection in primary immune deficiency disorders: an international case series. Diagn Microbiol Infect Dis. 2019;93(1):69\u201373.","journal-title":"Diagn Microbiol Infect Dis"},{"key":"1985_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11882-016-0597-6","volume":"16","author":"PJ Maglione","year":"2016","unstructured":"Maglione PJ. Autoimmune and Lymphoproliferative Complications of Common Variable Immunodeficiency. Curr Allergy Asthma Rep. 2016;16:1\u201310.","journal-title":"Curr Allergy Asthma Rep"},{"key":"1985_CR5","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1007\/s10875-012-9778-9","volume":"33","author":"J-N Boursiquot","year":"2013","unstructured":"Boursiquot J-N, G\u00e9rard L, Malphettes M, Fieschi C, Galicier L, Boutboul D, et al. Granulomatous Disease in CVID: Retrospective Analysis of Clinical Characteristics and Treatment Efficacy in a Cohort of 59 Patients. J Clin Immunol. 2013;33:84\u201395.","journal-title":"J Clin Immunol"},{"key":"1985_CR6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jaut.2010.10.002","volume":"36","author":"J Boileau","year":"2011","unstructured":"Boileau J, Mouillot G, G\u00e9rard L, Carmagnat M, Rabian C, Oksenhendler E, et al. Autoimmunity in common variable immunodeficiency: Correlation with lymphocyte phenotype in the French DEFI study. J Autoimmun. 2011;36:25\u201332.","journal-title":"J Autoimmun"},{"key":"1985_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2020.00149","volume":"11","author":"H Ho","year":"2020","unstructured":"Ho H, Cunningham-rundles C. Non-infectious Complications of Common Variable Immunodeficiency: Updated Clinical Spectrum, Sequelae, and Insights to Pathogenesis. Front Immunol. 2020;11:1\u201314.","journal-title":"Front Immunol"},{"key":"1985_CR8","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s12016-017-8638-z","volume":"55","author":"J Song","year":"2018","unstructured":"Song J, Lleo A, Yang GX, Zhang W. Common Variable Immunodeficiency and Liver Involvement. Clin Rev Allerg Immunol. 2018;55:340\u201351.","journal-title":"Clin Rev Allerg Immunol"},{"key":"1985_CR9","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1080\/1744666X.2019.1658523","volume":"15","author":"F Kiaee","year":"2019","unstructured":"Kiaee F, Azizi G, Rafiemanesh H, et al. Malignancy in common variable immunodeficiency: a systematic review and meta-analysis. Expert Rev Clin Immunol. 2019;15:1105\u201313.","journal-title":"Expert Rev Clin Immunol"},{"key":"1985_CR10","unstructured":"Seidel MG, Kindle G, Inf D, Gathmann B, Quinti I. The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity.:1763\u201370."},{"issue":"6","key":"1985_CR11","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1016\/j.jaip.2016.07.002","volume":"4","author":"R Bertinchamp","year":"2016","unstructured":"Bertinchamp R, G\u00e9rard L, Boutboul D, et al. Exclusion of Patients with a Severe T-Cell Defect Improves the Definition of Common Variable Immunodeficiency. J Allergy Clin Immunol Pract. 2016;4(6):1147\u201357.","journal-title":"J Allergy Clin Immunol Pract"},{"key":"1985_CR12","first-page":"77","volume":"111","author":"C Wehr","year":"2013","unstructured":"Wehr C, Kivioja T, Schmitt C, Ferry B, Witte T, Eren E, et al. The EUROclass trial: defining subgroups in common variable immunodeficiency. EUROclass trial : defining subgroups common variable immunodeficiency. 2013;111:77\u201385.","journal-title":"EUROclass trial : defining subgroups common variable immunodeficiency"},{"key":"1985_CR13","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1182\/blood-2007-11-124545","volume":"112","author":"H Chapel","year":"2008","unstructured":"Chapel H, Lucas M, Lee M, Bjorkander J, Webster D, Grimbacher B, et al. Common Variable immunodeficiency disorders: Division into distinct clinical phenotypes. Blood. 2008;112:277\u201386.","journal-title":"Blood"},{"key":"1985_CR14","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/j.jaci.2012.05.046","volume":"130","author":"H Chapel","year":"2012","unstructured":"Chapel H, Lucas M, Patel S, Lee M, Cunningham-Rundles C, Resnick E, et al. Confirmation and improvement of criteria for clinical phenotyping in common variable immunodeficiency disorders in replicate cohorts. J Allergy Clin Immunol. 2012;130:1197\u2013e11989.","journal-title":"J Allergy Clin Immunol"},{"key":"1985_CR15","unstructured":"Tuijnenburg P, Allen L, Burns SO, Greene D. Loss-of-function nuclear factor k B subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans. 2018;1:1285\u201396."},{"key":"1985_CR16","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1182\/blood-2011-09-377945","volume":"119","author":"ES Resnick","year":"2012","unstructured":"Resnick ES, Moshier EL, Godbold JH, Cunningham-rundles C. Morbidity and mortality in common variable immune deficiency over 4 decades. Blood. 2012;119:1650\u20137.","journal-title":"Blood"},{"key":"1985_CR17","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/j.jaip.2025.03.009","volume":"13","author":"P Bez","year":"2025","unstructured":"Bez P, Smits B, Geier C, Hirsch A, Caballero de Oyteza A, Proietti M, et al. Uncovering Risk Factors of Premature Mortality in Common Variable Immunodeficiency. J Allergy Clin Immunology: Pract. 2025;13:1201\u2013e120910.","journal-title":"J Allergy Clin Immunology: Pract"},{"key":"1985_CR18","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jhep.2007.08.011","volume":"48","author":"G Malamut","year":"2008","unstructured":"Malamut G, Ziol M, Suarez F, Beaugrand M, Lascaux AS, Verkarre V, et al. Nodular regenerative hyperplasia: The main liver disease in patients with primary hypogammaglobulinemia and hepatic abnormalities. J Hepatol. 2008;48:74\u201382.","journal-title":"J Hepatol"},{"key":"1985_CR19","first-page":"933463","volume":"13","author":"FMS Lima","year":"2022","unstructured":"Lima FMS, Toledo-barros M, Takakura C, Bernardes-silva CF, Karolina A, Berselli B, et al. Liver disease accompanied by enteropathy in common variable immunode fi ciency. Common pathophysiological Mech. 2022;13:933463.","journal-title":"Common pathophysiological Mech"},{"key":"1985_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2023.1268207","volume":"14","author":"LG Hanitsch","year":"2023","unstructured":"Hanitsch LG, Steiner S, Schumann M, Wittke K, Kedor C, Scheibenbogen C, et al. Portal hypertension in common variable immunodeficiency disorders \u2013 a single center analysis on clinical and immunological parameter in 196 patients. Front Immunol. 2023;14:1\u201313.","journal-title":"Front Immunol"},{"key":"1985_CR21","doi-asserted-by":"crossref","unstructured":"Fuss IJ, Friend J, Yang Z, Xi L, Raffeld M, Kleiner DE et al. Nodular Regenerative Hyperplasia in Common Variable Immunodeficiency. J Clin Immunol. 2013;748\u201358.","DOI":"10.1007\/s10875-013-9873-6"},{"key":"1985_CR22","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1111\/j.1365-2249.2008.03711.x","volume":"153","author":"C Ward","year":"2008","unstructured":"Ward C, Lucas M, Piris J. Abnormal liver function in common variable immunodeficiency disorders due to nodular regenerative hyperplasia. Clin Exp Immunol. 2008;153:331\u20137.","journal-title":"Clin Exp Immunol"},{"key":"1985_CR23","doi-asserted-by":"publisher","first-page":"672458","DOI":"10.1155\/2014\/672458","volume":"2014","author":"F Pulvirenti","year":"2014","unstructured":"Pulvirenti F, Pentassuglio I, Milito C, Valente M, Santis A, De, Conti V, et al. Idiopathic Non Cirrhotic Portal Hypertension and Spleno-Portal Axis Abnormalities in Patients with Severe Primary Antibody Deficiencies. J Immunol Res. 2014;2014:672458.","journal-title":"J Immunol Res"},{"key":"1985_CR24","doi-asserted-by":"publisher","first-page":"2484","DOI":"10.1016\/j.jaip.2019.04.016","volume":"7","author":"V Azzu","year":"2019","unstructured":"Azzu V, Fonseca M, Duckworth A, Kennard L, Moini N, Qurashi M, et al. Liver disease is common in patients with common variable immunodeficiency and predicts mortality in the presence of cirrhosis or portal hypertension. J Allergy Clin Immunol Pract. 2019;7:2484\u2013e24863.","journal-title":"J Allergy Clin Immunol Pract"},{"key":"1985_CR25","doi-asserted-by":"publisher","first-page":"e0322","DOI":"10.1097\/HC9.0000000000000322","volume":"8","author":"N Halliday","year":"2024","unstructured":"Halliday N, Eden N, Somers H, Burke N, Silva H, Gx C, et al. Common variable immunodeficiency disorder-related liver disease is common and results in portal hypertension and an increased risk of death. Hepatol Commun. 2024;8:e0322.","journal-title":"Hepatol Commun"},{"key":"1985_CR26","unstructured":"Franchis R, De, Bosch J, Garcia-tsao G, Reiberger T, Baveno. VII \u2013 Renewing consensus portal Hypertens. 2022;76."},{"issue":"5","key":"1985_CR27","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/S2468-1253(19)30047-0","volume":"4","author":"A De Gottardi","year":"2019","unstructured":"De Gottardi A, Rautou PE, Schouten J, et al. Porto-sinusoidal vascular disease: proposal and description of a novel entity. Lancet Gastroenterol Hepatol. 2019;4(5):399\u2013411.","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"1985_CR28","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.jhep.2024.07.035","volume":"82","author":"M Magaz","year":"2025","unstructured":"Magaz M, Giudicelli-Lett H, Abraldes JG, Nicoar\u0103-Farc\u0103u O, Turon F, Rajoriya N, et al. Porto-sinusoidal vascular liver disorder with portal hypertension: Natural history and long-term outcome. J Hepatol. 2025;82:72\u201383.","journal-title":"J Hepatol"},{"key":"1985_CR29","unstructured":"G\u00e9rard L, Garzaro M, Ferrer V, Malphettes M, Fieschi C, Garnier JL, Just N, Masseau A, Delaugerre C, Izopet J. Oksenhendler E AFD study group. Hepatitis E infection in adults with primary immunodeficiency with or without immunoglobulin replacement therapy. Blood Transfus. 2022;516\u201324."},{"key":"1985_CR30","unstructured":"ESID Registry Working Party. ESID Registry - Working definitions for clinical diagnosis of IEI. 2019;1\u201333."},{"key":"1985_CR31","doi-asserted-by":"crossref","unstructured":"Conley ME, Notarangelo LD, Etzioni A. at al. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol. 1999;93(3):190-197.","DOI":"10.1006\/clim.1999.4799"},{"key":"1985_CR32","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1086\/606059","volume":"49","author":"M Malphettes","year":"2009","unstructured":"Malphettes M, G\u00e9rard L, Carmagnat M, Mouillot G, Vince N, Boutboul D, et al. Late-Onset Combined Immune Deficiency: A Subset of Common Variable Immunodeficiency with Severe T Cell Defect. Clin Infect Dis. 2009;49:1329\u201338.","journal-title":"Clin Infect Dis"},{"issue":"2","key":"1985_CR33","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s12016-017-8645-0","volume":"4","author":"R Ameratunga","year":"2018","unstructured":"Ameratunga R, Lehnert K, Woon ST, et al. Review: Diagnosing Common Variable Immunodeficiency Disorder in the Era of Genome Sequencing. Clin Rev Allergy Immunol. 2018;4(2):261\u20138.","journal-title":"Clin Rev Allergy Immunol"},{"key":"1985_CR34","doi-asserted-by":"publisher","first-page":"2384","DOI":"10.3389\/fimmu.2018.02384","volume":"9","author":"LMA Janssen","year":"2018","unstructured":"Janssen LMA, Bassett P, Macken T, Van Esch J, Pruijt H, Knoops A, et al. Mild hypogammaglobulinemia can be a serious condition. Front Immunol. 2018;9:2384.","journal-title":"Front Immunol"},{"key":"1985_CR35","doi-asserted-by":"crossref","unstructured":"Sipos F. and MG. Good \u2019 s syndrome: brief overview of an enigmatic immune deficiency. 2023;698\u2013704.","DOI":"10.1111\/apm.13351"},{"issue":"2","key":"1985_CR36","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1586\/17474124.2014.869476","volume":"8","author":"EBC Burri","year":"2014","unstructured":"Burri EBC. The use of fecal calprotectin as a biomarker in gastrointestinal disease. Expert Rev Gastroenterol Hepatol. 2014;8(2):197\u2013210.","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"1985_CR37","doi-asserted-by":"crossref","unstructured":"Hercun J, Asif B, Vittal A, Ahmed A, Gopalakrishna Pillai HK, Bergerson JRE et al. Development of hepatic fibrosis in common variable immunodeficiency-related porto-sinusoidal vascular disorder. Alimentary pharmacology & therapeutics. England; 2024;60:888\u201396.","DOI":"10.1111\/apt.18180"},{"key":"1985_CR38","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1097\/PAS.0000000000001452","volume":"44","author":"R Crotty","year":"2020","unstructured":"Crotty R, Taylor MS, Farmer JR, Kakar S, Yilmaz F, Ardeniz \u00d6, et al. Spectrum of Hepatic Manifestations of Common Variable Immunodeficiency. Am J Surg Pathol. 2020;44:617\u201325.","journal-title":"Am J Surg Pathol"},{"key":"1985_CR39","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1007\/s10875-022-01319-0","volume":"42","author":"AM Globig","year":"2022","unstructured":"Globig AM, Strohmeier V, Surabattula R, Leeming DJ, Karsdal MA, Heeg M, et al. Evaluation of Laboratory and Sonographic Parameters for Detection of Portal Hypertension in Patients with Common Variable Immunodeficiency. J Clin Immunol. 2022;42:1626\u201337.","journal-title":"J Clin Immunol"},{"key":"1985_CR40","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.jceh.2019.11.005","volume":"10","author":"A Tanwar","year":"2020","unstructured":"Tanwar A, Gupta GK, Chauhan V, Sharma D, Jain MK, Bhardwaj H, et al. Celiac Disease and Portal Hypertension: A Causal Association or Just a Coincidence? J Clin Experimental Hepatol. 2020;10:290\u20135.","journal-title":"J Clin Experimental Hepatol"},{"key":"1985_CR41","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/j.dld.2023.11.021","volume":"56","author":"N Pugliese","year":"2024","unstructured":"Pugliese N, Giuli L, Mastrorocco E, Santopaolo F, Marcozzi G, Bezzio C, et al. Exploring the link: Porto-sinusoidal vascular disorder and inflammatory bowel disease \u2013 A comprehensive narrative review. Dig Liver Disease. 2024;56:964\u201370.","journal-title":"Dig Liver Disease"},{"key":"1985_CR42","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.jceh.2014.07.005","volume":"4","author":"A Goel","year":"2014","unstructured":"Goel A, Elias JE, Eapen CE, Ramakrishna B, Elias E. Idiopathic Non-Cirrhotic Intrahepatic Portal Hypertension (NCIPH)- Newer Insights into Pathogenesis and Emerging Newer Treatment Options. J Clin Experimental Hepatol. 2014;4:247\u201356.","journal-title":"J Clin Experimental Hepatol"},{"issue":"3","key":"1985_CR43","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/0016-5085(88)90255-7","volume":"94","author":"K Kono","year":"1988","unstructured":"Kono K, Ohnishi K, Omata M, et al. Experimental portal fibrosis produced by intraportal injection of killed nonpathogenic Escherichia coli in rabbits. Gastroenterology. 1988;94(3):787\u201396.","journal-title":"Gastroenterology"},{"key":"1985_CR44","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/j.humpath.2004.06.016","volume":"35","author":"M Ziol","year":"2004","unstructured":"Ziol M, Poirel H, Kountchou GN, Boyer O, Mohand D, Mouthon LUC, et al. Intrasinusoidal Cytotoxic CD8\u2009+\u2009T Cells in Nodular Regenerative Hyperplasia of the Liver. Hum Pathol. 2004;35:1241\u201351.","journal-title":"Hum Pathol"},{"key":"1985_CR45","doi-asserted-by":"crossref","unstructured":"Silva H, Gabriela C, Brito X, De, Hall A, Eden N, Somers H et al. Common variable immunodeficiency disorder (CVID) - \u00ad related liver disease: assessment of the main histological aspects using novel semiquantitative scoring systems, image analysis and correlation with clinical parameters of liver stiffness and portal hypertension. 2024;709\u201316.","DOI":"10.1136\/jcp-2023-208977"},{"key":"1985_CR46","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1038\/s41575-018-0020-y","volume":"15","author":"S Shetty","year":"2018","unstructured":"Shetty S, Lalor PF, Adams DH. Liver sinusoidal endothelial cells \u2014 gatekeepers of hepatic immunity. Nat Reviews Gastroenterol Hepatol. 2018;15:555\u201367.","journal-title":"Nat Reviews Gastroenterol Hepatol"},{"key":"1985_CR47","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1016\/j.jaci.2022.12.822","volume":"151","author":"Q Riller","year":"2023","unstructured":"Riller Q, Fourgeaud J, Bruneau J, De Ravin SS, Smith G, Fusaro M, et al. Late-onset enteric virus infection associated with hepatitis (EVAH) in transplanted SCID patients. J Allergy Clin Immunol. 2023;151:1634\u201345.","journal-title":"J Allergy Clin Immunol"},{"key":"1985_CR48","doi-asserted-by":"crossref","unstructured":"Bez P, Santangeli E, Goldacker S, Salzer U, Warnatz K. Expansion of CD57\u2009+\u2009CD8 T cells in common variable immunode fi ciency with hepatopathy and CMV infection. 2025;1\u201310.","DOI":"10.3389\/fimmu.2025.1577934"},{"key":"1985_CR49","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1016\/j.jhep.2022.05.033","volume":"77","author":"A Gottardi","year":"2022","unstructured":"Gottardi A, De, Sempoux C, Berzigotti A. Review Porto-sinusoidal vascular disorder. J Hepatol. 2022;77:1124\u201335.","journal-title":"J Hepatol"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10875-026-01985-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-026-01985-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-026-01985-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:25:34Z","timestamp":1773123934000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10875-026-01985-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,28]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1985"],"URL":"https:\/\/doi.org\/10.1007\/s10875-026-01985-4","relation":{},"ISSN":["1573-2592"],"issn-type":[{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,28]]},"assertion":[{"value":"7 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"29"}}