{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:10:12Z","timestamp":1789089012155,"version":"build-2803163510"},"reference-count":96,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":78,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"DOI":"10.1007\/s10875-026-02030-0","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T17:55:07Z","timestamp":1782410107000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intersection Between Systemic Autoimmune Diseases, Primary Immunodeficiency and Cancer: a Field in its Infancy"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9585-6167","authenticated-orcid":false,"given":"Silvia","family":"S\u00e1nchez-Ram\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2727-1707","authenticated-orcid":false,"given":"Ana Isabel","family":"Ramos-Lisbona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Yousuf","family":"Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"issue":"20","key":"2030_CR1","doi-asserted-by":"publisher","first-page":"4729","DOI":"10.3390\/jcm10204729","volume":"10","author":"G Costagliola","year":"2021","unstructured":"Costagliola G, Cappelli S, Consolini R. Autoimmunity in Primary Immunodeficiency Disorders: An Updated Review on Pathogenic and Clinical Implications. J Clin Med. 2021;10(20):4729.","journal-title":"J Clin Med"},{"issue":"5","key":"2030_CR2","doi-asserted-by":"publisher","first-page":"340","DOI":"10.2500\/aap.2024.45.240058","volume":"45","author":"C Chang","year":"2024","unstructured":"Chang C. Immunodysregulation in immunodeficiency. Allergy Asthma Proc. 2024;45(5):340\u20136.","journal-title":"Allergy Asthma Proc"},{"issue":"2","key":"2030_CR3","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.jaip.2020.12.024","volume":"9","author":"JR Farmer","year":"2021","unstructured":"Farmer JR, Uzel G. Mapping Out Autoimmunity Control in Primary Immune Regulatory Disorders. J Allergy Clin Immunol Pract. 2021;9(2):653\u20139.","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"2030_CR4","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/nrrheum.2017.198","volume":"14","author":"RE Schmidt","year":"2018","unstructured":"Schmidt RE, Grimbacher B, Witte T. Autoimmunity and primary immunodeficiency: two sides of the same coin? Nat Rev Rheumatol. 2018;14(1):7\u201318.","journal-title":"Nat Rev Rheumatol"},{"key":"2030_CR5","doi-asserted-by":"publisher","first-page":"104501","DOI":"10.1016\/j.ebiom.2023.104501","volume":"90","author":"G Sogkas","year":"2023","unstructured":"Sogkas G, Witte T. The link between rheumatic disorders and inborn errors of immunity. eBioMedicine. 2023;90:104501.","journal-title":"eBioMedicine"},{"issue":"1","key":"2030_CR6","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.jaci.2015.11.004","volume":"137","author":"B Grimbacher","year":"2016","unstructured":"Grimbacher B, Warnatz K, Yong PFK, Korganow AS, Peter HH. The crossroads of autoimmunity and immunodeficiency: Lessons from polygenic traits and monogenic defects. J Allergy Clin Immunol. 2016;137(1):3\u201317.","journal-title":"J Allergy Clin Immunol"},{"issue":"9","key":"2030_CR7","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1182\/blood.2019000923","volume":"135","author":"OM Delmonte","year":"2020","unstructured":"Delmonte OM, Villa A, Notarangelo LD. Immune dysregulation in patients with RAG deficiency and other forms of combined immune deficiency. Blood. 2020;135(9):610\u20139.","journal-title":"Blood"},{"issue":"6","key":"2030_CR8","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1016\/j.jaip.2023.04.018","volume":"11","author":"PE Gray","year":"2023","unstructured":"Gray PE, David C. Inborn Errors of Immunity and Autoimmune Disease. J Allergy Clin Immunol Pract. 2023;11(6):1602\u201322.","journal-title":"J Allergy Clin Immunol Pract"},{"key":"2030_CR9","doi-asserted-by":"publisher","first-page":"928062","DOI":"10.3389\/fimmu.2022.928062","volume":"13","author":"M Ballow","year":"2022","unstructured":"Ballow M, S\u00e1nchez-Ram\u00f3n S, Walter JE. Secondary Immune Deficiency and Primary Immune Deficiency Crossovers: Hematological Malignancies and Autoimmune Diseases. Front Immunol. 2022;13:928062.","journal-title":"Front Immunol"},{"issue":"suppl 10","key":"2030_CR10","first-page":"abstract2116","volume":"71","author":"L Lindsay","year":"2019","unstructured":"Lindsay L, Chuo C, Jones N, Galanter J, McGregor A, Tuckwell K. Serious Infection in Patients with Systemic Lupus Erythematosus, Lupus Nephritis and Rheumatoid Arthritis Compared to the General Population: Incidence Rates Using Real-World Claims Data [abstract]. Arthritis Rheumatol. 2019;71(suppl 10):abstract2116.","journal-title":"Arthritis Rheumatol"},{"issue":"2","key":"2030_CR11","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s40744-022-00525-x","volume":"10","author":"WN Huang","year":"2023","unstructured":"Huang WN, Chuo CY, Lin CH, Chen YM, Lin WS, Tuckwell K, et al. Serious Infection Rates Among Patients with Select Autoimmune Conditions: A Claims-Based Retrospective Cohort Study from Taiwan and the USA. Rheumatol Ther. 2023;10(2):387\u2013404.","journal-title":"Rheumatol Ther"},{"issue":"1","key":"2030_CR12","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jaci.2015.10.023","volume":"137","author":"M Her","year":"2016","unstructured":"Her M, Kavanaugh A. Alterations in immune function with biologic therapies for autoimmune disease. J Allergy Clin Immunol. 2016;137(1):19\u201327.","journal-title":"J Allergy Clin Immunol"},{"issue":"10","key":"2030_CR13","first-page":"678","volume":"39","author":"WH Chou","year":"2021","unstructured":"Chou WH, McGregor B, Schmidt A, Carvalho FLF, Hirsch MS, Chang SL, et al. Cyclophosphamide-associated bladder cancers and considerations for survivorship care: A systematic review. Urol Oncol Semin Orig Investig. 2021;39(10):678\u201385.","journal-title":"Urol Oncol Semin Orig Investig"},{"issue":"10","key":"2030_CR14","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1007\/s00296-021-04969-2","volume":"41","author":"D Daoussis","year":"2021","unstructured":"Daoussis D, Leonidou L, Kalogeropoulou C, Paliogianni F, Tzouvelekis A. Protracted severe COVID-19 pneumonia following rituximab treatment: caution needed. Rheumatol Int. 2021;41(10):1839\u201343.","journal-title":"Rheumatol Int"},{"key":"2030_CR15","doi-asserted-by":"publisher","first-page":"1605243","DOI":"10.3389\/fimmu.2025.1605243","volume":"16","author":"SH Liu","year":"2025","unstructured":"Liu SH, Wang SH, Zuo YG. Efficacy and safety of low dose rituximab in pemphigus: an updated systematic review and meta-analysis. Front Immunol. 2025;16:1605243.","journal-title":"Front Immunol"},{"issue":"11","key":"2030_CR16","doi-asserted-by":"publisher","first-page":"1900","DOI":"10.1093\/rheumatology\/kez337","volume":"58","author":"GE Fragoulis","year":"2019","unstructured":"Fragoulis GE, Conway R, Nikiphorou E. Methotrexate and interstitial lung disease: controversies and questions. A narrative review of the literature. Rheumatology. 2019;58(11):1900\u20136.","journal-title":"Rheumatology"},{"issue":"12","key":"2030_CR17","doi-asserted-by":"publisher","first-page":"e14248","DOI":"10.1111\/apha.14248","volume":"240","author":"M Berber","year":"2024","unstructured":"Berber M, Penton D. Calcineurin inhibitors and the renin\u2013angiotensin\u2013aldosterone system. Acta Physiol. 2024;240(12):e14248.","journal-title":"Acta Physiol"},{"key":"2030_CR18","doi-asserted-by":"publisher","first-page":"1497921","DOI":"10.3389\/fimmu.2024.1497921","volume":"15","author":"M Cortesi","year":"2024","unstructured":"Cortesi M, Dotta L, Cattalini M, Lougaris V, Soresina A, Badolato R. Unmasking inborn errors of immunity: identifying the red flags of immune dysregulation. Front Immunol. 2024;15:1497921.","journal-title":"Front Immunol"},{"key":"2030_CR19","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/0896-8411(92)90034-N","volume":"5","author":"AD Steinberg","year":"1992","unstructured":"Steinberg AD, Krieg AM, Takashi T, Gourley MF. Timing of immunosuppression in the natural history of autoimmune disease. J Autoimmun. 1992;5:197\u2013203.","journal-title":"J Autoimmun"},{"key":"2030_CR20","doi-asserted-by":"crossref","unstructured":"Mikuls TR, Johnson SR, Fraenkel L, Arasaratnam RJ, Baden LR, Bermas BL et al. American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID-19 Pandemic: Version 3. Arthritis Rheumatol. 2021;73(2):e1\u2013e12.","DOI":"10.1002\/art.41596"},{"issue":"5","key":"2030_CR21","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1097\/00002281-200309000-00002","volume":"15","author":"I Kang","year":"2003","unstructured":"Kang I, Park SH. Infectious complications in SLE after immunosuppressive therapies. Curr Opin Rheumatol. 2003;15(5):528\u201334.","journal-title":"Curr Opin Rheumatol"},{"issue":"Supplement1","key":"2030_CR22","doi-asserted-by":"publisher","first-page":"i22","DOI":"10.1093\/rheumatology\/keac678","volume":"62","author":"J He","year":"2023","unstructured":"He J, Li Z. Dilemma of immunosuppression and infection risk in systemic lupus erythematosus. Rheumatology. 2023;62(Supplement1):i22\u20139.","journal-title":"Rheumatology"},{"issue":"2","key":"2030_CR23","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1002\/art.39849","volume":"69","author":"CH Feldman","year":"2017","unstructured":"Feldman CH, Marty FM, Winkelmayer WC, Guan H, Franklin JM, Solomon DH, et al. Comparative Rates of Serious Infections Among Patients With Systemic Lupus Erythematosus Receiving Immunosuppressive Medications. Arthritis Rheumatol. 2017;69(2):387\u201397.","journal-title":"Arthritis Rheumatol"},{"issue":"21","key":"2030_CR24","doi-asserted-by":"publisher","first-page":"e25985","DOI":"10.1097\/MD.0000000000025985","volume":"100","author":"S Lanjewar","year":"2021","unstructured":"Lanjewar S, McFarlane IM, Parker KN, Saad H, Haddadin M, Hirsch E, et al. Long-term immunosuppression and multiple transplants predispose systemic lupus erythematosus patients with cytopenias to hematologic malignancies. Med (Baltim). 2021;100(21):e25985.","journal-title":"Med (Baltim)"},{"issue":"4","key":"2030_CR25","doi-asserted-by":"publisher","first-page":"e005866","DOI":"10.1136\/rmdopen-2025-005866","volume":"11","author":"EWY Hsieh","year":"2025","unstructured":"Hsieh EWY, Chung JB, Amin A, Askanase AD, Bartok B, Brunetta P, et al. Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner\/disciplinary working group perspective. RMD Open. 2025;11(4):e005866.","journal-title":"RMD Open"},{"issue":"2","key":"2030_CR26","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/ajg.2016.537","volume":"112","author":"FA Farraye","year":"2017","unstructured":"Farraye FA, Melmed GY, Lichtenstein GR, Kane SV. ACG Clinical Guideline: Preventive Care in Inflammatory Bowel Disease. Am J Gastroenterol. 2017;112(2):241\u201358.","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"2030_CR27","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/j.jaad.2023.11.039","volume":"90","author":"EE Granger","year":"2024","unstructured":"Granger EE, Groover M, Harwood C, Proby CM, Karn E, Murad F, et al. Cutaneous squamous cell carcinoma tumor accrual rates in immunosuppressed patients with autoimmune and inflammatory conditions: A retrospective cohort study. J Am Acad Dermatol. 2024;90(4):731\u20138.","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"2030_CR28","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1136\/ard-2022-223356","volume":"82","author":"JS Smolen","year":"2023","unstructured":"Smolen JS, Landew\u00e9 RBM, Bergstra SA, Kerschbaumer A, Sepriano A, Aletaha D, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update. Ann Rheum Dis. 2023;82(1):3\u201318.","journal-title":"Ann Rheum Dis"},{"key":"2030_CR29","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1038\/ajg.2011.58","volume":"106","author":"NJ Talley","year":"2011","unstructured":"Talley NJ, Abreu MT, Achkar JP, Bernstein CN, Dubinsky MC, Hanauer SB, et al. An Evidence-Based Systematic Review on Medical Therapies for Inflammatory Bowel Disease. Am J Gastroenterol. 2011;106:S2\u201325.","journal-title":"Am J Gastroenterol"},{"key":"2030_CR30","doi-asserted-by":"publisher","first-page":"115706","DOI":"10.1016\/j.biopha.2023.115706","volume":"168","author":"X D\u00edaz-Villamar\u00edn","year":"2023","unstructured":"D\u00edaz-Villamar\u00edn X, Fern\u00e1ndez-Var\u00f3n E, Rojas Romero MC, Callejas-Rubio JL, Cabeza-Barrera J, Rodr\u00edguez-Nogales A, et al. Azathioprine dose tailoring based on pharmacogenetic information: Insights of clinical implementation. Biomed Pharmacother. 2023;168:115706.","journal-title":"Biomed Pharmacother"},{"issue":"3","key":"2030_CR31","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.cgh.2018.07.013","volume":"17","author":"L Beaugerie","year":"2019","unstructured":"Beaugerie L, Kirchgesner J. Balancing Benefit vs Risk of Immunosuppressive Therapy for Individual Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019;17(3):370\u20139.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2030_CR32","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.bcp.2019.04.009","volume":"165","author":"I Petta","year":"2019","unstructured":"Petta I, Peene I, Elewaut D, Vereecke L, De Bosscher K. Risks and benefits of corticosteroids in arthritic diseases in the clinic. Biochem Pharmacol. 2019;165:112\u201325.","journal-title":"Biochem Pharmacol"},{"issue":"8","key":"2030_CR33","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s40266-020-00775-w","volume":"37","author":"S Rajasimhan","year":"2020","unstructured":"Rajasimhan S, Pamuk O, Katz JD. Safety of Janus Kinase Inhibitors in Older Patients: A Focus on the Thromboembolic Risk. Drugs Aging. 2020;37(8):551\u20138.","journal-title":"Drugs Aging"},{"issue":"4","key":"2030_CR34","doi-asserted-by":"publisher","first-page":"3183","DOI":"10.1007\/s00210-024-03569-8","volume":"398","author":"G Rathi","year":"2025","unstructured":"Rathi G, Shamkuwar PB, Rathi K, Ranazunjare R, Kulkarni S. Contemporary and prospective use of azathioprine (AZA) in viral, rheumatic, and dermatological disorders: a review of pharmacogenomic and nanotechnology applications. Naunyn Schmiedebergs Arch Pharmacol. 2025;398(4):3183\u201397.","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"10","key":"2030_CR35","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1080\/14740338.2017.1361404","volume":"16","author":"G Murdaca","year":"2017","unstructured":"Murdaca G, Negrini S, Magnani O, Penza E, Pellecchio M, Puppo F. Impact of pharmacogenomics upon the therapeutic response to etanercept in psoriasis and psoriatic arthritis. Expert Opin Drug Saf. 2017;16(10):1173\u20139.","journal-title":"Expert Opin Drug Saf"},{"issue":"3","key":"2030_CR36","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/j.jaci.2023.11.021","volume":"153","author":"R Bacchetta","year":"2024","unstructured":"Bacchetta R, Roncarolo MG. IPEX syndrome from diagnosis to cure, learning along the way. J Allergy Clin Immunol. 2024;153(3):595\u2013605.","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"2030_CR37","doi-asserted-by":"publisher","first-page":"389","DOI":"10.3324\/haematol.2012.067488","volume":"98","author":"O Lambotte","year":"2013","unstructured":"Lambotte O, Neven B, Galicier L, Magerus-Chatinet A, Schleinitz N, Hermine O, et al. Diagnosis of autoimmune lymphoproliferative syndrome caused by FAS deficiency in adults. Haematologica. 2013;98(3):389\u201392.","journal-title":"Haematologica"},{"issue":"7","key":"2030_CR38","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1007\/s12519-022-00545-1","volume":"18","author":"W Wang","year":"2022","unstructured":"Wang W, Wang W, He TY, Zou LP, Li WD, Yu ZX, et al. Analysis of clinical characteristics of children with Aicardi-Goutieres syndrome in China. World J Pediatr. 2022;18(7):490\u20137.","journal-title":"World J Pediatr"},{"issue":"1","key":"2030_CR39","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/cei.13600","volume":"205","author":"M Jamee","year":"2021","unstructured":"Jamee M, Hosseinzadeh S, Sharifinejad N, Zaki-Dizaji M, Matloubi M, Hasani M, et al. Comprehensive comparison between 222 CTLA-4 haploinsufficiency and 212 LRBA deficiency patients: a systematic review. Clin Exp Immunol. 2021;205(1):28\u201343.","journal-title":"Clin Exp Immunol"},{"issue":"8","key":"2030_CR40","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1111\/pedi.13426","volume":"23","author":"SAW Greeley","year":"2022","unstructured":"Greeley SAW, Polak M, Nj\u00f8lstad PR, Barbetti F, Williams R, Castano L, et al. ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes. 2022;23(8):1188\u2013211.","journal-title":"Pediatr Diabetes"},{"key":"2030_CR41","doi-asserted-by":"publisher","first-page":"2496","DOI":"10.3389\/fimmu.2018.02496","volume":"9","author":"JM Alperin","year":"2018","unstructured":"Alperin JM, Ortiz-Fern\u00e1ndez L, Sawalha AH. Monogenic Lupus: A Developing Paradigm of Disease. Front Immunol. 2018;9:2496.","journal-title":"Front Immunol"},{"issue":"4","key":"2030_CR42","doi-asserted-by":"publisher","first-page":"e653","DOI":"10.1016\/j.cgh.2021.03.021","volume":"20","author":"R Nambu","year":"2022","unstructured":"Nambu R, Warner N, Mulder DJ, Kotlarz D, McGovern DPB, Cho J, et al. A Systematic Review of Monogenic Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2022;20(4):e653\u201363.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2030_CR43","doi-asserted-by":"publisher","first-page":"48","DOI":"10.21037\/dmr-20-149","volume":"3","author":"T Hammer","year":"2020","unstructured":"Hammer T, Langholz E. The epidemiology of inflammatory bowel disease: balance between East and West? A narrative review. Dig Med Res. 2020;3:48\u201348.","journal-title":"Dig Med Res"},{"issue":"3","key":"2030_CR44","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.ecl.2010.05.011","volume":"39","author":"DM Maahs","year":"2010","unstructured":"Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ. Epidemiology of Type 1 Diabetes. Endocrinol Metab Clin North Am. 2010;39(3):481\u201397.","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"9563","key":"2030_CR45","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/S0140-6736(07)60363-8","volume":"369","author":"A Ravelli","year":"2007","unstructured":"Ravelli A, Martini A. Juvenile idiopathic arthritis. Lancet. 2007;369(9563):767\u201378.","journal-title":"Lancet"},{"key":"2030_CR46","unstructured":"Kaur J, Jialal I, Hashimoto Thyroiditis. En: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025. Available from: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459262\/"},{"issue":"4","key":"2030_CR47","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1007\/s00415-023-12047-9","volume":"271","author":"A Habbestad","year":"2024","unstructured":"Habbestad A, Willumsen JS, Aarseth JH, Grytten N, Midgard R, Wergeland S, et al. Increasing age of multiple sclerosis onset from 1920 to 2022: a population-based study. J Neurol. 2024;271(4):1610\u20137.","journal-title":"J Neurol"},{"issue":"1","key":"2030_CR48","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1038\/s41598-022-04836-5","volume":"12","author":"B Gbaguidi","year":"2022","unstructured":"Gbaguidi B, Guillemin F, Soudant M, Debouverie M, Mathey G, Epstein J. Age-period-cohort analysis of the incidence of multiple sclerosis over twenty years in Lorraine, France. Sci Rep. 2022;12(1):1001.","journal-title":"Sci Rep"},{"issue":"19","key":"2030_CR49","doi-asserted-by":"publisher","first-page":"3089","DOI":"10.1016\/j.scib.2024.04.075","volume":"69","author":"M Li","year":"2024","unstructured":"Li M, Li C, Cao M, Lu K, Wu C, Wang J, et al. Incidence and prevalence of systemic lupus erythematosus in urban China, 2013\u20132017: A nationwide population-based study. Sci Bull. 2024;69(19):3089\u201397.","journal-title":"Sci Bull"},{"issue":"7","key":"2030_CR50","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.3899\/jrheum.151221","volume":"43","author":"MLF Hermansen","year":"2016","unstructured":"Hermansen MLF, Lindhardsen J, Torp-Pedersen C, Faurschou M, Jacobsen S. Incidence of Systemic Lupus Erythematosus and Lupus Nephritis in Denmark: A Nationwide Cohort Study. J Rheumatol. 2016;43(7):1335\u20139.","journal-title":"J Rheumatol"},{"issue":"1","key":"2030_CR51","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.berh.2016.03.001","volume":"30","author":"G Egiziano","year":"2016","unstructured":"Egiziano G, Bernatsky S, Shah AA. Cancer and autoimmunity: Harnessing longitudinal cohorts to probe the link. Best Pract Res Clin Rheumatol. 2016;30(1):53\u201362.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"5","key":"2030_CR52","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/cac2.12283","volume":"42","author":"Z Zhou","year":"2022","unstructured":"Zhou Z, Liu H, Yang Y, Zhou J, Zhao L, Chen H, et al. The five major autoimmune diseases increase the risk of cancer: epidemiological data from a large-scale cohort study in China. Cancer Commun. 2022;42(5):435\u201346.","journal-title":"Cancer Commun"},{"key":"2030_CR53","doi-asserted-by":"crossref","unstructured":"Cao L, Tong H, Xu G, Liu P, Meng H, Wang J et al. Systemic Lupus Erythematous and Malignancy Risk: A Meta-Analysis. Scheurer M, editor. PLOS ONE. 2015;10(4):e0122964.","DOI":"10.1371\/journal.pone.0122964"},{"issue":"6","key":"2030_CR54","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1016\/j.semarthrit.2021.09.009","volume":"51","author":"AE Clarke","year":"2021","unstructured":"Clarke AE, Pooley N, Marjenberg Z, Langham J, Nicholson L, Langham S, et al. Risk of malignancy in patients with systemic lupus erythematosus: Systematic review and meta-analysis. Semin Arthritis Rheum. 2021;51(6):1230\u201341.","journal-title":"Semin Arthritis Rheum"},{"issue":"5","key":"2030_CR55","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1097\/BOR.0000000000000202","volume":"27","author":"GC Goobie","year":"2015","unstructured":"Goobie GC, Bernatsky S, Ramsey-Goldman R, Clarke AE. Malignancies in systemic lupus erythematosus: a 2015 update. Curr Opin Rheumatol. 2015;27(5):454\u201360.","journal-title":"Curr Opin Rheumatol"},{"issue":"10","key":"2030_CR56","doi-asserted-by":"publisher","first-page":"e693","DOI":"10.1016\/S2665-9913(24)00183-8","volume":"6","author":"AV Goules","year":"2024","unstructured":"Goules AV, Chatzis L, Pezoulas VC, Patsouras M, Mavragani C, Quartuccio L, et al. Identification and evolution of predictors of Sj\u00f6gren\u2019s disease-associated mucosa-associated lymphoid tissue lymphoma development over time: a case-control study. Lancet Rheumatol. 2024;6(10):e693\u2013702.","journal-title":"Lancet Rheumatol"},{"issue":"3","key":"2030_CR57","doi-asserted-by":"publisher","first-page":"587","DOI":"10.55730\/1300-0144.5350","volume":"52","author":"B Aslan","year":"2022","unstructured":"Aslan B, \u00d6\u011f\u00fct TS, Erbasan F, Di\u0307Lbi\u0307L M, \u00c7eli\u0307K E, Terzi\u0307O\u011flu ME, et al. The risk of cancer in patients with primary Sj\u00f6grensyndrome; A single-center study from Turkey. Turk J Med Sci. 2022;52(3):587\u201395.","journal-title":"Turk J Med Sci"},{"issue":"1","key":"2030_CR58","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s10067-017-3676-8","volume":"37","author":"HL Wang","year":"2018","unstructured":"Wang HL, Zhou YM, Zhu GZ, Yang Z, Hua BJ. Malignancy as a comorbidity in rheumatic diseases: a retrospective hospital-based study. Clin Rheumatol. 2018;37(1):81\u20135.","journal-title":"Clin Rheumatol"},{"issue":"2","key":"2030_CR59","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1002\/ijc.24287","volume":"125","author":"LA Anderson","year":"2009","unstructured":"Anderson LA, Gadalla S, Morton LM, Landgren O, Pfeiffer R, Warren JL, et al. Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies. Int J Cancer. 2009;125(2):398\u2013405.","journal-title":"Int J Cancer"},{"key":"2030_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/8631061","volume":"2016","author":"S Yadlapati","year":"2016","unstructured":"Yadlapati S, Efthimiou P. Autoimmune\/Inflammatory Arthritis Associated Lymphomas: Who Is at Risk? BioMed Res Int. 2016;2016:1\u201311.","journal-title":"BioMed Res Int"},{"issue":"8","key":"2030_CR61","doi-asserted-by":"publisher","first-page":"4029","DOI":"10.1182\/blood-2007-10-119974","volume":"111","author":"K Ekstr\u00f6m Smedby","year":"2008","unstructured":"Ekstr\u00f6m Smedby K, Vajdic CM, Falster M, Engels EA, Mart\u00ednez-Maza O, Turner J, et al. Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium. Blood. 2008;111(8):4029\u201338.","journal-title":"Blood"},{"issue":"1","key":"2030_CR62","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1038\/s41584-024-01188-4","volume":"21","author":"NA Allameen","year":"2025","unstructured":"Allameen NA, Ramos-Lisbona AI, Wedderburn LR, Lundberg IE, Isenberg DA. An update on autoantibodies in the idiopathic inflammatory myopathies. Nat Rev Rheumatol. 2025;21(1):46\u201362.","journal-title":"Nat Rev Rheumatol"},{"issue":"12","key":"2030_CR63","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/s41584-023-01045-w","volume":"19","author":"AGS Oldroyd","year":"2023","unstructured":"Oldroyd AGS, Callen JP, Chinoy H, Chung L, Fiorentino D, Gordon P, et al. International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative. Nat Rev Rheumatol. 2023;19(12):805\u201317.","journal-title":"Nat Rev Rheumatol"},{"issue":"3","key":"2030_CR64","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.jaci.2023.12.022","volume":"153","author":"MG Seidel","year":"2024","unstructured":"Seidel MG, Hauck F. Multilayer concept of autoimmune mechanisms and manifestations in inborn errors of immunity: Relevance for precision therapy. J Allergy Clin Immunol. 2024;153(3):615\u2013e6284.","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"2030_CR65","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1136\/ard-2024-225735","volume":"84","author":"JU Scher","year":"2025","unstructured":"Scher JU, Nayak R, Clemente JC. Microbiome research in autoimmune and immune-mediated inflammatory diseases: lessons, advances and unmet needs. Ann Rheum Dis. 2025;84(1):9\u201313.","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"2030_CR66","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1093\/cei\/uxac057","volume":"209","author":"WA Shaheen","year":"2022","unstructured":"Shaheen WA, Quraishi MN, Iqbal TH. Gut microbiome and autoimmune disorders. Clin Exp Immunol. 2022;209(2):161\u201374.","journal-title":"Clin Exp Immunol"},{"issue":"4","key":"2030_CR67","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1007\/s12026-023-09365-5","volume":"71","author":"Y Peng","year":"2023","unstructured":"Peng Y, Chen Y, Wang Y, Wang W, Qiao S, Lan J, et al. Dysbiosis and primary B-cell immunodeficiencies: current knowledge and future perspective. Immunol Res. 2023;71(4):528\u201336.","journal-title":"Immunol Res"},{"issue":"6","key":"2030_CR68","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1007\/s11926-012-0281-3","volume":"14","author":"A Agha","year":"2012","unstructured":"Agha A, Bateman H, Sterrett A, Valeriano-Marcet J. Myelodysplasia and Malignancy-Associated Vasculitis. Curr Rheumatol Rep. 2012;14(6):526\u201331.","journal-title":"Curr Rheumatol Rep"},{"key":"2030_CR69","doi-asserted-by":"publisher","first-page":"855445","DOI":"10.3389\/fped.2022.855445","volume":"10","author":"G Costagliola","year":"2022","unstructured":"Costagliola G, Peroni DG, Consolini R. Beyond Infections: New Warning Signs for Inborn Errors of Immunity in Children. Front Pediatr. 2022;10:855445.","journal-title":"Front Pediatr"},{"issue":"5","key":"2030_CR70","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/j.semarthrit.2020.07.002","volume":"50","author":"AL Roupie","year":"2020","unstructured":"Roupie AL, Guedon A, Terrier B, Lahuna C, Jachiet V, Regent A, et al. Vasculitis associated with myelodysplastic syndrome and chronic myelomonocytic leukemia: French multicenter case-control study. Semin Arthritis Rheum. 2020;50(5):879\u201384.","journal-title":"Semin Arthritis Rheum"},{"issue":"8","key":"2030_CR71","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1002\/art.41774","volume":"73","author":"M Maz","year":"2021","unstructured":"Maz M, Chung SA, Abril A, Langford CA, Gorelik M, Guyatt G, et al. 2021 American College of Rheumatology\/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis. Arthritis Rheumatol. 2021;73(8):1349\u201365.","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"2030_CR72","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1136\/ard.60.3.293","volume":"60","author":"MA Hamidou","year":"2001","unstructured":"Hamidou MA, El Kouri D, Audrain M, Grolleau JY. Systemic antineutrophil cytoplasmic antibody vasculitis associated with lymphoid neoplasia. Ann Rheum Dis. 2001;60(3):293\u20135.","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"2030_CR73","doi-asserted-by":"publisher","first-page":"e253","DOI":"10.1016\/S2665-9913(24)00094-8","volume":"6","author":"The Lancet Rheumatology","year":"2024","unstructured":"The Lancet Rheumatology. Vasculitis: the promising road ahead. Lancet Rheumatol. 2024;6(5):e253.","journal-title":"Lancet Rheumatol"},{"key":"2030_CR74","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jaut.2019.01.011","volume":"99","author":"L Amaya-Uribe","year":"2019","unstructured":"Amaya-Uribe L, Rojas M, Azizi G, Anaya JM, Gershwin ME. Primary immunodeficiency and autoimmunity: A comprehensive review. J Autoimmun. 2019;99:52\u201372.","journal-title":"J Autoimmun"},{"issue":"5","key":"2030_CR75","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1097\/BOR.0000000000000091","volume":"26","author":"SM Maggadottir","year":"2014","unstructured":"Maggadottir SM, Sullivan KE. The intersection of immune deficiency and autoimmunity. Curr Opin Rheumatol. 2014;26(5):570\u20138.","journal-title":"Curr Opin Rheumatol"},{"issue":"3","key":"2030_CR76","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1136\/annrheumdis-2020-218280","volume":"80","author":"G Sogkas","year":"2021","unstructured":"Sogkas G, Dubrowinskaja N, Adriawan IR, Anim M, Witte T, Schmidt RE, et al. High frequency of variants in genes associated with primary immunodeficiencies in patients with rheumatic diseases with secondary hypogammaglobulinaemia. Ann Rheum Dis. 2021;80(3):392\u20139.","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"2030_CR77","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.autrev.2017.03.003","volume":"16","author":"J Day","year":"2017","unstructured":"Day J, Limaye V, Proudman S, Hayball JD, Hissaria P. The utility of monitoring peripheral blood lymphocyte subsets by flow cytometric analysis in patients with rheumatological diseases treated with rituximab. Autoimmun Rev. 2017;16(5):542\u20137.","journal-title":"Autoimmun Rev"},{"issue":"11","key":"2030_CR78","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1136\/annrheumdis-2017-211191","volume":"76","author":"MY Md Yusof","year":"2017","unstructured":"Md Yusof MY, Shaw D, El-Sherbiny YM, Dunn E, Rawstron AC, Emery P, et al. Predicting and managing primary and secondary non-response to rituximab using B-cell biomarkers in systemic lupus erythematosus. Ann Rheum Dis. 2017;76(11):1829\u201336.","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"2030_CR79","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1136\/ard-2023-224489","volume":"83","author":"R Zonozi","year":"2024","unstructured":"Zonozi R, Cortazar FB, Jeyabalan A, Sauvage G, Nithagon P, Huizenga NR, et al. Maintenance of remission of ANCA vasculitis by rituximab based on B cell repopulation versus serological flare: a randomised trial. Ann Rheum Dis. 2024;83(3):351\u20139.","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"2030_CR80","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.jaci.2017.01.004","volume":"139","author":"LD Notarangelo","year":"2017","unstructured":"Notarangelo LD, Fleisher TA. Targeted strategies directed at the molecular defect: Toward precision medicine for select primary immunodeficiency disorders. J Allergy Clin Immunol. 2017;139(3):715\u201323.","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"2030_CR81","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1097\/ACI.0000000000000431","volume":"18","author":"JW Leiding","year":"2018","unstructured":"Leiding JW, Ballow M. Precision medicine in the treatment of primary immunodeficiency diseases. Curr Opin Allergy Clin Immunol. 2018;18(2):159\u201366.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"2030_CR82","doi-asserted-by":"publisher","first-page":"1029560","DOI":"10.3389\/fimmu.2022.1029560","volume":"13","author":"MV Pinto","year":"2022","unstructured":"Pinto MV, Neves JF. Precision medicine: The use of tailored therapy in primary immunodeficiencies. Front Immunol. 2022;13:1029560.","journal-title":"Front Immunol"},{"issue":"3","key":"2030_CR83","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/j.jaip.2018.12.017","volume":"7","author":"JW Leiding","year":"2019","unstructured":"Leiding JW, Forbes LR. Mechanism-Based Precision Therapy for the Treatment of Primary Immunodeficiency and Primary Immunodysregulatory Diseases. J Allergy Clin Immunol Pract. 2019;7(3):761\u201373.","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"2030_CR84","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s12016-016-8591-2","volume":"52","author":"P Vignesh","year":"2017","unstructured":"Vignesh P, Rawat A, Singh S. An Update on the Use of Immunomodulators in Primary Immunodeficiencies. Clin Rev Allergy Immunol. 2017;52(2):287\u2013303.","journal-title":"Clin Rev Allergy Immunol"},{"key":"2030_CR85","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3389\/fimmu.2017.00937","volume":"8","author":"BE Marciano","year":"2017","unstructured":"Marciano BE, Holland SM. Primary Immunodeficiency Diseases: Current and Emerging Therapeutics. Front Immunol. 2017;8:937.","journal-title":"Front Immunol"},{"issue":"7","key":"2030_CR86","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1097\/MPH.0000000000002940","volume":"46","author":"P Cao","year":"2024","unstructured":"Cao P, Zhang X, Fu Y, Wang H, Yu Y, Zhu X, et al. XMEN-associated Systemic EBV-positive T-cell Lymphoma of Childhood: Report of Two Cases and Literature Review. J Pediatr Hematol Oncol. 2024;46(7):356\u201363.","journal-title":"J Pediatr Hematol Oncol"},{"issue":"2","key":"2030_CR87","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/S0049-0172(96)80044-8","volume":"26","author":"MD Wooten","year":"1996","unstructured":"Wooten MD, Jasin HE. Vasculitis and lymph op roliferative diseases. Semin Arthritis Rheum. 1996;26(2):564\u201374.","journal-title":"Semin Arthritis Rheum"},{"issue":"3","key":"2030_CR88","doi-asserted-by":"publisher","first-page":"S71","DOI":"10.1016\/j.kint.2023.10.008","volume":"105","author":"J Floege","year":"2024","unstructured":"Floege J, Jayne DRW, Sanders JSF, Tesar V, Rovin BH. KDIGO 2024 Clinical Practice Guideline for the Management of Antineutrophil Cytoplasmic Antibody (ANCA)\u2013Associated Vasculitis. Kidney Int. 2024;105(3):S71\u2013116.","journal-title":"Kidney Int"},{"issue":"1","key":"2030_CR89","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1136\/ard-2022-223764","volume":"83","author":"B Hellmich","year":"2024","unstructured":"Hellmich B, Sanchez-Alamo B, Schirmer JH, Berti A, Blockmans D, Cid MC, et al. EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. Ann Rheum Dis. 2024;83(1):30\u201347.","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"2030_CR90","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12016-022-08942-0","volume":"65","author":"GT Padron","year":"2022","unstructured":"Padron GT, Hernandez-Trujillo VP. Autoimmunity in Primary Immunodeficiencies (PID). Clin Rev Allergy Immunol. 2022;65(1):1\u201318.","journal-title":"Clin Rev Allergy Immunol"},{"issue":"2","key":"2030_CR91","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1016\/j.jaip.2020.10.057","volume":"9","author":"AA Mauracher","year":"2021","unstructured":"Mauracher AA, Gujer E, Bachmann LM, G\u00fcsewell S, Pachlopnik Schmid J. Patterns of Immune Dysregulation in Primary Immunodeficiencies: A Systematic Review. J Allergy Clin Immunol Pract. 2021;9(2):792\u2013e80210.","journal-title":"J Allergy Clin Immunol Pract"},{"key":"2030_CR92","doi-asserted-by":"publisher","first-page":"2753","DOI":"10.3389\/fimmu.2019.02753","volume":"10","author":"JD Gereige","year":"2019","unstructured":"Gereige JD, Maglione PJ. Current Understanding and Recent Developments in Common Variable Immunodeficiency Associated Autoimmunity. Front Immunol. 2019;10:2753.","journal-title":"Front Immunol"},{"issue":"1","key":"2030_CR93","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jaci.2022.11.001","volume":"151","author":"A Long","year":"2023","unstructured":"Long A, Kleiner A, Looney RJ. Immune dysregulation. J Allergy Clin Immunol. 2023;151(1):70\u201380.","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"2030_CR94","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1097\/ACI.0000000000000583","volume":"19","author":"M Kitcharoensakkul","year":"2019","unstructured":"Kitcharoensakkul M, Cooper MA. Rheumatologic and autoimmune manifestations in primary immune deficiency. Curr Opin Allergy Clin Immunol. 2019;19(6):545\u201352.","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"2030_CR95","doi-asserted-by":"publisher","first-page":"3094","DOI":"10.3389\/fimmu.2019.03094","volume":"10","author":"MF Khan","year":"2020","unstructured":"Khan MF, Wang H. Environmental Exposures and Autoimmune Diseases: Contribution of Gut Microbiome. Front Immunol. 2020;10:3094.","journal-title":"Front Immunol"},{"key":"2030_CR96","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.jaut.2017.03.009","volume":"83","author":"B Chen","year":"2017","unstructured":"Chen B, Sun L, Zhang X. Integration of microbiome and epigenome to decipher the pathogenesis of autoimmune diseases. J Autoimmun. 2017;83:31\u201342.","journal-title":"J Autoimmun"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10875-026-02030-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-026-02030-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10875-026-02030-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:02:32Z","timestamp":1789088552000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10875-026-02030-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,25]]},"references-count":96,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2030"],"URL":"https:\/\/doi.org\/10.1007\/s10875-026-02030-0","relation":{},"ISSN":["1573-2592"],"issn-type":[{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,25]]},"assertion":[{"value":"14 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"87"}}