{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T21:25:21Z","timestamp":1746653121558,"version":"3.37.3"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T00:00:00Z","timestamp":1581897600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T00:00:00Z","timestamp":1581897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Monit Comput"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1007\/s10877-020-00464-4","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T15:06:56Z","timestamp":1581952016000},"page":"175-181","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Low-dose droperidol suppresses transcranial electrical motor-evoked potential amplitude: a retrospective study"],"prefix":"10.1007","volume":"35","author":[{"given":"Hiroyuki","family":"Deguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1893-4384","authenticated-orcid":false,"given":"Kenta","family":"Furutani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Mitsuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Baba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,2,17]]},"reference":[{"key":"464_CR1","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1097\/EJA.0b013e328352813f","volume":"29","author":"I Schaub","year":"2012","unstructured":"Schaub I, Lysakowski C, Elia N, Tram\u00e8r MR. Low-dose droperidol (\u2264 1 mg or \u2264 15 \u00b5g kg\u22121) for the prevention of postoperative nausea and vomiting in adults: quantitative systematic review of randomised controlled trials. Eur J Anaesthesiol. 2012;29:286\u201394. https:\/\/doi.org\/10.1097\/EJA.0b013e328352813f.","journal-title":"Eur J Anaesthesiol"},{"key":"464_CR2","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/BF03018945","volume":"47","author":"I Henzi","year":"2000","unstructured":"Henzi I, Sonderegger J, Tram\u00e8r MR. Efficacy, dose-response, and adverse effects of droperidol for prevention of postoperative nausea and vomiting. Can J Anaesth. 2000;47:537\u201351. https:\/\/doi.org\/10.1007\/BF03018945.","journal-title":"Can J Anaesth"},{"key":"464_CR3","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1097\/ALN.0b013e31827dde8d","volume":"118","author":"GA Nuttall","year":"2013","unstructured":"Nuttall GA, Malone AM, Michels CA, Trudell LC, Renk TD, Marienau ME, Oliver WC, Ackerman MJ. Does low-dose droperidol increase the risk of polymorphic ventricular tachycardia or death in the surgical patient? Anesthesiology. 2013;118:382\u20136. https:\/\/doi.org\/10.1097\/ALN.0b013e31827dde8d.","journal-title":"Anesthesiology"},{"key":"464_CR4","doi-asserted-by":"publisher","first-page":"E6","DOI":"10.3171\/2009.8.FOCUS09150","volume":"27","author":"AA Gonzalez","year":"2009","unstructured":"Gonzalez AA, Jeyanandarajan D, Hansen C, Zada G, Hsieh PC. Intraoperative neurophysiological monitoring during spine surgery: a review. Neurosurg Focus. 2009;27:E6. https:\/\/doi.org\/10.3171\/2009.8.FOCUS09150.","journal-title":"Neurosurg Focus"},{"key":"464_CR5","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1016\/S1388-2457(02)00027-5","volume":"113","author":"L Pelosi","year":"2002","unstructured":"Pelosi L, Lamb J, Grevitt M, Mehdian SM, Webb JK, Blumhardt LD. Combined monitoring of motor and somatosensory evoked potentials in orthopaedic spinal surgery. Clin Neurophysiol. 2002;113:1082\u201391. https:\/\/doi.org\/10.1016\/S1388-2457(02)00027-5.","journal-title":"Clin Neurophysiol"},{"key":"464_CR6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3171\/2010.9.SPINE1085","volume":"14","author":"P Park","year":"2011","unstructured":"Park P, Wang AC, Sangala JR, Kim SM, Hervey-Jumper S, Than KD, Farokhrani A, Lamarca F. Impact of multimodal intraoperative monitoring during correction of symptomatic cervical or cervicothoracic kyphosis. J Neurosurg Spine. 2011;14:99\u2013105. https:\/\/doi.org\/10.3171\/2010.9.SPINE1085.","journal-title":"J Neurosurg Spine"},{"key":"464_CR7","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1097\/01.BRS.0000061995.75709.78","volume":"28","author":"DD Langeloo","year":"2003","unstructured":"Langeloo DD, Lelivelt A, Journee HL, Louis Journ\u00e9e H, Slappendel R, de Kleuver M. Transcranial electrical motor-evoked potential monitoring during surgery for spinal deformity: a study of 145 patients. Spine. 2003;28:1043\u201350. https:\/\/doi.org\/10.1097\/01.BRS.0000061995.75709.78.","journal-title":"Spine"},{"key":"464_CR8","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1093\/bja\/aeg211","volume":"91","author":"N Nathan","year":"2003","unstructured":"Nathan N, Tabaraud F, Lacroix F, Mouli\u00e8s D, Viviand X, Lansade A, Terrier G, Feiss P. Influence of propofol concentrations on multipulse transcranial motor evoked potentials. Br J Anaesth. 2003;91:493\u20137. https:\/\/doi.org\/10.1093\/bja\/aeg211.","journal-title":"Br J Anaesth"},{"key":"464_CR9","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1227\/00006123-199412000-00008","volume":"35","author":"CJ Kalkman","year":"1994","unstructured":"Kalkman CJ, Drummond JC, Patel PM, Sano T, Chesnut RM. Effects of droperidol, pentobarbital, and ketamine on myogenic transcranial magnetic motor-evoked responses in humans. Neurosurgery. 1994;35:1066\u201371. https:\/\/doi.org\/10.1227\/00006123-199412000-00008.","journal-title":"Neurosurgery"},{"key":"464_CR10","doi-asserted-by":"publisher","first-page":"53","DOI":"10.5152\/TJAR.2016.50336","volume":"45","author":"\u00c1 Saponaro Gonz\u00e1lez","year":"2017","unstructured":"Saponaro Gonz\u00e1lez \u00c1, P\u00e9rez Lorensu PJ, Chaves G\u00f3mez S, Nodarse Medina JF, Torres Dios J. What can we learn from two consecutive cases? Droperidol may abolish TcMEPs. Turk J Anaesthesiol Reanim. 2017;45:53\u20135. https:\/\/doi.org\/10.5152\/TJAR.2016.50336.","journal-title":"Turk J Anaesthesiol Reanim"},{"key":"464_CR11","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/00000542-199701000-00004","volume":"86","author":"CF Minto","year":"1997","unstructured":"Minto CF, Schnider TW, Egan TD, Youngs E, Lemmens HJ, Gambus PL, Billard V, Hoke JF, Moore KH, Hermann DJ, Muir KT, Mandema JW, Shafer SL. Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development. Anesthesiology. 1997;86:10\u201323. https:\/\/doi.org\/10.1097\/00000542-199701000-00004.","journal-title":"Anesthesiology"},{"key":"464_CR12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1111\/j.1365-2044.2007.05391.x","volume":"63","author":"T Kunisawa","year":"2008","unstructured":"Kunisawa T, Nagashima M, Suzuki A, Takahata O, Iwasaki H. Calculating variable 'alpha' for predicting plasma concentrations of steady-state remifentanil. Anaesthesia. 2008;63:103\u20134. https:\/\/doi.org\/10.1111\/j.1365-2044.2007.05391.x.","journal-title":"Anaesthesia"},{"key":"464_CR13","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1007\/s00540-010-0961-y","volume":"24","author":"T Kunisawa","year":"2010","unstructured":"Kunisawa T, Nagashima M, Suzuki A, Takahata O, Iwasaki H. The range of values of \"variable alpha\" when predicting plasma concentrations and\/or effect site concentrations of remifentanil is huge. J Anesth. 2010;24:656\u20137. https:\/\/doi.org\/10.1007\/s00540-010-0961-y.","journal-title":"J Anesth"},{"key":"464_CR14","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/00000542-198802000-00013","volume":"68","author":"SL Shafer","year":"1988","unstructured":"Shafer SL, Siegel LC, Cooke JE, Scott JC. Testing computer-controlled infusion pumps by simulation. Anesthesiology. 1988;68:261\u20136. https:\/\/doi.org\/10.1097\/00000542-198802000-00013.","journal-title":"Anesthesiology"},{"key":"464_CR15","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1097\/00000542-199012000-00005","volume":"73","author":"SL Shafer","year":"1990","unstructured":"Shafer SL, Varvel JR, Aziz N, Scott JC. Pharmacokinetics of fentanyl administered by computer-controlled infusion pump. Anesthesiology. 1990;73:1091\u2013102. https:\/\/doi.org\/10.1097\/00000542-199012000-00005.","journal-title":"Anesthesiology"},{"key":"464_CR16","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1097\/00008506-199106000-00006","volume":"3","author":"RF Ghaly","year":"1991","unstructured":"Ghaly RF, Stone JL, Levy WJ, Kartha R, Brunner EA, Aldrete JA, Laege R. The effect of neuroleptanalgesia (droperiodol-fentanyl) on motor potentials evoked by transcranial magnetic stimulation in the monkey. J Neurosurg Anesthesiol. 1991;3:117\u201323. https:\/\/doi.org\/10.1097\/00008506-199106000-00006.","journal-title":"J Neurosurg Anesthesiol"},{"key":"464_CR17","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3171\/2013.10.SPINE12944","volume":"20","author":"S Kobayashi","year":"2014","unstructured":"Kobayashi S, Matsuyama Y, Shinomiya K, Kawabata S, Ando M, Kanchiku T, Saito T, Takahashi M, Ito Z, Muramoto A, Fujiwara Y, Kida K, Yamada K, Wada K, Yamamoto N, Satomi K, Tani T. A new alarm point of transcranial electrical stimulation motor evoked potentials for intraoperative spinal cord monitoring: a prospective multicenter study from the Spinal Cord Monitoring Working Group of the Japanese Society for Spine Surgery and Related Research. J Neurosurg Spine. 2014;20:102\u20137. https:\/\/doi.org\/10.3171\/2013.10.SPINE12944.","journal-title":"J Neurosurg Spine"},{"key":"464_CR18","first-page":"246","volume":"25","author":"JF Cassady Jr","year":"2000","unstructured":"Cassady JF Jr, Lederhaas G, Cancel DD, Cummings RJ, Loveless EA. A randomized comparison of the effects of continuous thoracic epidural analgesia and intravenous patient-controlled analgesia after posterior spinal fusion in adolescents. Reg Anesth Pain Med. 2000;25:246\u201353.","journal-title":"Reg Anesth Pain Med"},{"key":"464_CR19","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1111\/j.1460-9592.2004.01387.x","volume":"14","author":"JF O'Hara Jr","year":"2004","unstructured":"O'Hara JF Jr, Cywinski JB, Tetzlaff JE, Xu M, Gurd AR, Andrish JT. The effect of epidural vs intravenous analgesia for posterior spinal fusion surgery. Paediatr Anaesth. 2004;14:1009\u201315. https:\/\/doi.org\/10.1111\/j.1460-9592.2004.01387.x.","journal-title":"Paediatr Anaesth"},{"key":"464_CR20","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1093\/bja\/aep177","volume":"103","author":"CC Apfel","year":"2009","unstructured":"Apfel CC, Cakmakkaya OS, Frings G, Kranke P, Malhotra A, Stader A, Turan A, Biedler A, Kolodzie K. Droperidol has comparable clinical efficacy against both nausea and vomiting. Br J Anaesth. 2009;103:359\u201363. https:\/\/doi.org\/10.1093\/bja\/aep177.","journal-title":"Br J Anaesth"},{"key":"464_CR21","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1213\/00000539-199911000-00030","volume":"89","author":"A Macario","year":"1999","unstructured":"Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg. 1999;89:652\u20138.","journal-title":"Anesth Analg"},{"key":"464_CR22","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/BF00304763","volume":"24","author":"A Hamik","year":"1989","unstructured":"Hamik A, Peroutka SJ. Differential interactions of traditional and novel antiemetics with dopamine D 2 and 5-hydroxytryptamine 3 receptors. Cancer Chemother Pharmacol. 1989;24:307\u201310. https:\/\/doi.org\/10.1007\/BF00304763.","journal-title":"Cancer Chemother Pharmacol"},{"key":"464_CR23","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/S0006-8993(00)02066-7","volume":"863","author":"EJ Heyer","year":"2000","unstructured":"Heyer EJ, Flood P. Droperidol suppresses spontaneous electrical activity in neurons cultured from ventral midbrain: implications for neuroleptanesthesia. Brain Res. 2000;863:20\u20134. https:\/\/doi.org\/10.1016\/S0006-8993(00)02066-7.","journal-title":"Brain Res"},{"key":"464_CR24","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1126\/science.3854","volume":"192","author":"I Creese","year":"1976","unstructured":"Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science. 1976;192:481\u20133. https:\/\/doi.org\/10.1126\/science.3854.","journal-title":"Science"},{"key":"464_CR25","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1097\/00000542-200204000-00029","volume":"96","author":"P Flood","year":"2002","unstructured":"Flood P, Coates KM. Droperidol inhibits GABA(A) and neuronal nicotinic receptor activation. Anesthesiology. 2002;96:987\u201393. https:\/\/doi.org\/10.1097\/00000542-200204000-00029.","journal-title":"Anesthesiology"},{"key":"464_CR26","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1097\/00000542-200006000-00026","volume":"92","author":"A Olschewski","year":"2000","unstructured":"Olschewski A, Br\u00e4u ME, Hempelmann G, Vogel W, Safronov BV. Differential block of fast and slow inactivating tetrodotoxin-sensitive sodium channels by droperidol in spinal dorsal horn neurons. Anesthesiology. 2000;92:1667\u201376. https:\/\/doi.org\/10.1097\/00000542-200006000-00026.","journal-title":"Anesthesiology"},{"key":"464_CR27","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1213\/01.ANE.0000048517.98692.53","volume":"96","author":"M Nakayama","year":"2003","unstructured":"Nakayama M, Kanaya N, Ichinose H, Yamamoto S, Namiki A. Intravenous droperidol causes a reduction in the bispectral index in propofol-sedated patients during spinal anesthesia. Anesth Analg. 2003;96:765\u20138. https:\/\/doi.org\/10.1213\/01.ANE.0000048517.98692.53.","journal-title":"Anesth Analg"}],"container-title":["Journal of Clinical Monitoring and Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10877-020-00464-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10877-020-00464-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10877-020-00464-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T21:55:36Z","timestamp":1693518936000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10877-020-00464-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,17]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["464"],"URL":"https:\/\/doi.org\/10.1007\/s10877-020-00464-4","relation":{},"ISSN":["1387-1307","1573-2614"],"issn-type":[{"type":"print","value":"1387-1307"},{"type":"electronic","value":"1573-2614"}],"subject":[],"published":{"date-parts":[[2020,2,17]]},"assertion":[{"value":"4 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"This study was approved by the Ethics Committee of Niigata University Medical and Dental Hospital, Niigata, Japan (Approval No. 2017-0246). The Ethics Committee waived the requirement for written informed consent due to the retrospective nature of this study; however, patients received opt-out notices on the hospital\u2019s web site and information flyers were posted in the hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}}]}}