{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:06:55Z","timestamp":1793236015402,"version":"4.5.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Joint Project of Anesthesiology and Pharmacology","award":["2021lcxk002"],"award-info":[{"award-number":["2021lcxk002"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Monit Comput"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s10877-024-01126-5","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T08:02:41Z","timestamp":1705910561000},"page":"613-621","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study"],"prefix":"10.1007","volume":"38","author":[{"given":"Pan-Pan","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Wen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-Xi","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Xiang","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,22]]},"reference":[{"issue":"3","key":"1126_CR1","doi-asserted-by":"publisher","first-page":"M146","DOI":"10.1093\/gerona\/56.3.m146","volume":"56","author":"P Linda","year":"2001","unstructured":"Linda P, Fried, Catherine M, Tangen JW. Frailty in older adults: evidence for a phenotype. J Gerontol. 2001;56(3):M146\u201356. https:\/\/doi.org\/10.1093\/gerona\/56.3.m146.","journal-title":"J Gerontol"},{"issue":"9868","key":"1126_CR2","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/s0140-6736(12)62167-9","volume":"381","author":"A Clegg","year":"2013","unstructured":"Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. The Lancet. 2013;381(9868):752\u201362. https:\/\/doi.org\/10.1016\/s0140-6736(12)62167-9.","journal-title":"The Lancet"},{"issue":"6","key":"1126_CR3","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1001\/jamasurg.2015.5085","volume":"1","author":"DI McIsaac","year":"2016","unstructured":"McIsaac DI, Bryson GL, van Walraven C. Association of Frailty and 1-Year postoperative mortality following major elective noncardiac surgery: a Population-based Cohort Study. JAMA Surg Jun. 2016;1(6):538\u201345. https:\/\/doi.org\/10.1001\/jamasurg.2015.5085.","journal-title":"JAMA Surg Jun"},{"issue":"5","key":"1126_CR4","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.bja.2020.07.003","volume":"125","author":"DI McIsaac","year":"2020","unstructured":"McIsaac DI, Taljaard M, Bryson GL, et al. Frailty and long-term postoperative disability trajectories: a prospective multicentre cohort study. Br J Anaesth Nov. 2020;125(5):704\u201311. https:\/\/doi.org\/10.1016\/j.bja.2020.07.003.","journal-title":"Br J Anaesth Nov"},{"issue":"3","key":"1126_CR5","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s40520-021-01961-5","volume":"21","author":"S Esmaeeli","year":"2021","unstructured":"Esmaeeli S, Franco-Garcia E, Akeju O, et al. Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients. Aging Clin Exp Res Aug. 2021;21(3):625\u201331. https:\/\/doi.org\/10.1007\/s40520-021-01961-5.","journal-title":"Aging Clin Exp Res Aug"},{"issue":"2","key":"1126_CR6","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.bja.2021.11.018","volume":"128","author":"R Chan","year":"2022","unstructured":"Chan R, Ueno R, Afroz A, Billah B, Tiruvoipati R, Subramaniam A. Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis. Br J Anaesth Feb. 2022;128(2):258\u201371. https:\/\/doi.org\/10.1016\/j.bja.2021.11.018.","journal-title":"Br J Anaesth Feb"},{"issue":"10206","key":"1126_CR7","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1016\/s0140-6736(19)31786-6","volume":"394","author":"EO Hoogendijk","year":"2019","unstructured":"Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. The Lancet. 2019;394(10206):1365\u201375. https:\/\/doi.org\/10.1016\/s0140-6736(19)31786-6.","journal-title":"The Lancet"},{"issue":"6","key":"1126_CR8","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1213\/ANE.0000000000004602","volume":"130","author":"DI McIsaac","year":"2020","unstructured":"McIsaac DI, MacDonald DB, Aucoin SD. Frailty for Perioperative clinicians: a narrative review. Anesth Analg Jun. 2020;130(6):1450\u201360. https:\/\/doi.org\/10.1213\/ANE.0000000000004602.","journal-title":"Anesth Analg Jun"},{"issue":"2","key":"1126_CR9","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1213\/ANE.0000000000005609","volume":"1","author":"TJ Gracie","year":"2021","unstructured":"Gracie TJ, Caufield-Noll C, Wang NY, Sieber FE. The Association of Preoperative Frailty and Postoperative Delirium: a Meta-analysis. Anesth Analg Aug. 2021;1(2):314\u201323. https:\/\/doi.org\/10.1213\/ANE.0000000000005609.","journal-title":"Anesth Analg Aug"},{"issue":"6","key":"1126_CR10","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1213\/ANE.0000000000004773","volume":"130","author":"E Mahanna-Gabrielli","year":"2020","unstructured":"Mahanna-Gabrielli E, Zhang K, Sieber FE, et al. Frailty is Associated with postoperative Delirium but Not with Postoperative Cognitive decline in older noncardiac surgery patients. Anesth Analg Jun. 2020;130(6):1516\u201323. https:\/\/doi.org\/10.1213\/ANE.0000000000004773.","journal-title":"Anesth Analg Jun"},{"issue":"6","key":"1126_CR11","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1016\/j.surg.2021.05.048","volume":"170","author":"CM Wang","year":"2021","unstructured":"Wang CM, Ma YL, Yang XY, Ji RQ, Gu WJ, Zhou JX. Association of preoperative frailty with postoperative delirium after elective brain tumor resection: retrospective analysis of a prospective cohort. Surg Dec. 2021;170(6):1763\u20139. https:\/\/doi.org\/10.1016\/j.surg.2021.05.048.","journal-title":"Surg Dec"},{"issue":"3","key":"1126_CR12","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/ALN.0000000000002323","volume":"129","author":"KK MacKenzie","year":"2018","unstructured":"MacKenzie KK, Britt-Spells AM, Sands LP, Leung JM. Processed Electroencephalogram Monitoring and Postoperative Delirium: a systematic review and Meta-analysis. Anesthesiology Sep. 2018;129(3):417\u201327. https:\/\/doi.org\/10.1097\/ALN.0000000000002323.","journal-title":"Anesthesiology Sep"},{"issue":"S1","key":"1126_CR13","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1111\/anae.15607","volume":"77","author":"CJ Swarbrick","year":"2022","unstructured":"Swarbrick CJ, Partridge JSL. Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review. Anaesthesia. 2022;77(S1):92\u2013101. https:\/\/doi.org\/10.1111\/anae.15607.","journal-title":"Anaesthesia"},{"issue":"2","key":"1126_CR14","doi-asserted-by":"publisher","first-page":"e263","DOI":"10.1016\/j.bja.2022.11.002","volume":"130","author":"PP Fang","year":"2023","unstructured":"Fang PP, Shang ZX, Xu J, et al. Contribution of intraoperative electroencephalogram suppression to frailty-associated postoperative delirium: mediation analysis of a prospective surgical cohort. Br J Anaesth Feb. 2023;130(2):e263\u201371. https:\/\/doi.org\/10.1016\/j.bja.2022.11.002.","journal-title":"Br J Anaesth Feb"},{"issue":"9596","key":"1126_CR15","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1016\/s0140-6736(07)61602-x","volume":"370","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. The strengthening the reporting of Observational studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. The Lancet. 2007;370(9596):1453\u20137. https:\/\/doi.org\/10.1016\/s0140-6736(07)61602-x.","journal-title":"The Lancet"},{"key":"1126_CR16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.ejim.2016.03.007","volume":"31","author":"E Dent","year":"2016","unstructured":"Dent E, Kowal P, Hoogendijk EO. Frailty measurement in research and clinical practice: a review. Eur J Intern Med Jun. 2016;31:3\u201310. https:\/\/doi.org\/10.1016\/j.ejim.2016.03.007.","journal-title":"Eur J Intern Med Jun"},{"issue":"7","key":"1126_CR17","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.jamda.2017.01.009","volume":"1","author":"I Aprahamian","year":"2017","unstructured":"Aprahamian I, Cezar NOC, Izbicki R, et al. Screening for Frailty with the FRAIL scale: a comparison with the phenotype Criteria. J Am Med Dir Assoc Jul. 2017;1(7):592\u20136. https:\/\/doi.org\/10.1016\/j.jamda.2017.01.009.","journal-title":"J Am Med Dir Assoc Jul"},{"issue":"Suppl 1","key":"1126_CR18","doi-asserted-by":"publisher","first-page":"i46","DOI":"10.1093\/bja\/aev213","volume":"115","author":"PL Purdon","year":"2015","unstructured":"Purdon PL, Pavone KJ, Akeju O, et al. The ageing brain: age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia. Br J Anaesth Jul. 2015;115(Suppl 1):i46\u2013i57. https:\/\/doi.org\/10.1093\/bja\/aev213.","journal-title":"Br J Anaesth Jul"},{"issue":"2","key":"1126_CR19","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1097\/ALN.0000000000001717","volume":"127","author":"JM Lee","year":"2017","unstructured":"Lee JM, Akeju O, Terzakis K, et al. A prospective study of Age-dependent changes in Propofol-induced Electroencephalogram oscillations in Children. Anesthesiology Aug. 2017;127(2):293\u2013306. https:\/\/doi.org\/10.1097\/ALN.0000000000001717.","journal-title":"Anesthesiology Aug"},{"issue":"5","key":"1126_CR20","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1097\/ALN.0000000000003182","volume":"132","author":"M Kreuzer","year":"2020","unstructured":"Kreuzer M, Stern MA, Hight D, et al. Spectral and entropic features are altered by age in the Electroencephalogram in patients under Sevoflurane Anesthesia. Anesthesiology May. 2020;132(5):1003\u201316. https:\/\/doi.org\/10.1097\/ALN.0000000000003182.","journal-title":"Anesthesiology May"},{"issue":"5","key":"1126_CR21","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/j.bja.2020.12.042","volume":"126","author":"SL Eagleman","year":"2021","unstructured":"Eagleman SL, Drover CM, Li X, MacIver MB, Drover DR. Offline comparison of processed electroencephalogram monitors for anaesthetic-induced electroencephalogram changes in older adults. Br J Anaesth May. 2021;126(5):975\u201384. https:\/\/doi.org\/10.1016\/j.bja.2020.12.042.","journal-title":"Br J Anaesth May"},{"issue":"12","key":"1126_CR22","doi-asserted-by":"publisher","first-page":"2299","DOI":"10.1016\/j.neurobiolaging.2010.01.013","volume":"32","author":"CC Chen","year":"2011","unstructured":"Chen CC, Tung YY, Chang C. A lifespan MRI evaluation of ventricular enlargement in normal aging mice. Neurobiol Aging Dec. 2011;32(12):2299\u2013307. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2010.01.013.","journal-title":"Neurobiol Aging Dec"},{"issue":"4","key":"1126_CR23","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1038\/nrn3200","volume":"7","author":"JH Morrison","year":"2012","unstructured":"Morrison JH, Baxter MG. The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat Rev Neurosci Mar. 2012;7(4):240\u201350. https:\/\/doi.org\/10.1038\/nrn3200.","journal-title":"Nat Rev Neurosci Mar"},{"issue":"3\u20134","key":"1126_CR24","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s10548-011-0198-6","volume":"24","author":"SM McGinnis","year":"2011","unstructured":"McGinnis SM, Brickhouse M, Pascual B, Dickerson BC. Age-related changes in the thickness of cortical zones in humans. Brain Topogr Oct. 2011;24(3\u20134):279\u201391. https:\/\/doi.org\/10.1007\/s10548-011-0198-6.","journal-title":"Brain Topogr Oct"},{"issue":"4","key":"1126_CR25","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.bja.2020.06.054","volume":"125","author":"HA Kaiser","year":"2020","unstructured":"Kaiser HA, Hirschi T, Sleigh C, et al. Comorbidity-dependent changes in alpha and broadband electroencephalogram power during general anaesthesia for cardiac surgery. Br J Anaesth Oct. 2020;125(4):456\u201365. https:\/\/doi.org\/10.1016\/j.bja.2020.06.054.","journal-title":"Br J Anaesth Oct"},{"key":"1126_CR26","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3389\/fnsys.2017.00024","volume":"11","author":"CM Giattino","year":"2017","unstructured":"Giattino CM, Gardner JE, Sbahi FM, et al. Intraoperative Frontal Alpha-Band Power Correlates with preoperative neurocognitive function in older adults. Front Syst Neurosci. 2017;11:24. https:\/\/doi.org\/10.3389\/fnsys.2017.00024.","journal-title":"Front Syst Neurosci"},{"issue":"1","key":"1126_CR27","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1213\/ANE.0000000000005262","volume":"1","author":"RG Gutierrez","year":"2021","unstructured":"Gutierrez RG, Egana JI, Maldonado FA, et al. Association between Lower Preoperative Cognition with Intraoperative Electroencephalographic features consistent with Deep States of Anesthesia in older patients: an Observational Cohort Study. Anesth Analg Jul. 2021;1(1):205\u201314. https:\/\/doi.org\/10.1213\/ANE.0000000000005262.","journal-title":"Anesth Analg Jul"},{"issue":"1","key":"1126_CR28","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1097\/ALN.0000000000002775","volume":"131","author":"PE Vlisides","year":"2019","unstructured":"Vlisides PE, Mashour GA. Pharmacologic unmasking of neurologic deficits: a stress test for the brain. Anesthesiology Jul. 2019;131(1):5\u20136. https:\/\/doi.org\/10.1097\/ALN.0000000000002775.","journal-title":"Anesthesiology Jul"},{"issue":"4","key":"1126_CR29","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1097\/00000542-199810000-00023","volume":"89","author":"IJ Rampil","year":"1998","unstructured":"Rampil IJ. A primer for EEG Signal Processing in Anesthesia. Anesthesiology. 1998;89(4):980\u20131002. https:\/\/doi.org\/10.1097\/00000542-199810000-00023.","journal-title":"Anesthesiology"},{"issue":"6","key":"1126_CR30","first-page":"466","volume":"2","author":"H Li","year":"2011","unstructured":"Li H, Manwani B, Leng SX. Frailty, inflammation, and immunity. Aging and Disease. 2011;2(6):466\u201373.","journal-title":"Aging and Disease"},{"issue":"5","key":"1126_CR31","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1159\/000211949","volume":"55","author":"PO Lang","year":"2009","unstructured":"Lang PO, Michel JP, Zekry D. Frailty syndrome: a transitional state in a dynamic process. Gerontology. 2009;55(5):539\u201349. https:\/\/doi.org\/10.1159\/000211949.","journal-title":"Gerontology"},{"issue":"4","key":"1126_CR32","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1080\/21551197.2011.623931","volume":"30","author":"RA Heuberger","year":"2011","unstructured":"Heuberger RA. The frailty syndrome: a comprehensive review. J Nutr Gerontol Geriatr. 2011;30(4):315\u201368. https:\/\/doi.org\/10.1080\/21551197.2011.623931.","journal-title":"J Nutr Gerontol Geriatr"},{"issue":"1\u20132","key":"1126_CR33","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1159\/000502950","volume":"48","author":"S Koch","year":"2019","unstructured":"Koch S, Feinkohl I, Chakravarty S, et al. Cognitive impairment is Associated with Absolute Intraoperative Frontal alpha-Band Power but not with baseline alpha-Band Power: a pilot study. Dement Geriatr Cogn Disord. 2019;48(1\u20132):83\u201392. https:\/\/doi.org\/10.1159\/000502950.","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1126_CR34","doi-asserted-by":"publisher","unstructured":"Koch S, Windmann V, Chakravarty S, et al. Perioperative Electroencephalogram Spectral Dynamics Related to postoperative delirium in older patients. Anesth Analg Sep. 2021;27. https:\/\/doi.org\/10.1213\/ANE.0000000000005668.","DOI":"10.1213\/ANE.0000000000005668"},{"issue":"6","key":"1126_CR35","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1097\/ALN.0000000000004754","volume":"1","author":"S Dragovic","year":"2023","unstructured":"Dragovic S, Schneider G, Garcia PS, et al. Predictors of low risk for Delirium during Anesthesia Emergence. Anesthesiology Dec. 2023;1(6):757\u201368. https:\/\/doi.org\/10.1097\/ALN.0000000000004754.","journal-title":"Anesthesiology Dec"}],"container-title":["Journal of Clinical Monitoring and Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10877-024-01126-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10877-024-01126-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10877-024-01126-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T10:13:15Z","timestamp":1718014395000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10877-024-01126-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,22]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1126"],"URL":"https:\/\/doi.org\/10.1007\/s10877-024-01126-5","relation":{},"ISSN":["1387-1307","1573-2614"],"issn-type":[{"value":"1387-1307","type":"print"},{"value":"1573-2614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,22]]},"assertion":[{"value":"14 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors declare that they have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the ethics committee of the First Affiliated Hospital of Anhui Medical University, Hefei, China (Chairperson Prof. Hei Wang) on November 14, 2019 (approval number: PJ2019-15-18).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}