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Consequences of too few alerts are missed detections of oncoming complications, and too many alerts result in over-alerting and over-treatment. This study aimed to describe duration and deviation of vital signs in postoperative patients without complications when monitored continuously. Adult patients admitted to the general ward after major surgery were included. Continuous wireless vital sign monitoring (CVSM) was performed during the early postoperative period, with data collection blinded to ward nurses. For peripheral oxygen saturation (SpO\u2082), systolic blood pressure, heart rate, and respiratory rate, the longest consecutive durations outside predefined thresholds were identified. The primary outcome was the longest consecutive duration of SpO\u2082 &lt; 88%. A total of 600 patients were analyzed and of these, 277 patients had no complications of any kind. The longest sustained episodes with SpO\n                    <jats:sub>2<\/jats:sub>\n                    \u2009&lt;\u200988% were median 9\u00a0min [IQR 2\u201331\u00a0min]. The maximum length of other vital sign sustained deviations had the following median duration in minutes: SpO\n                    <jats:sub>2<\/jats:sub>\n                    \u2009&lt;\u200992%: 58[6 -129], HR\u2009&gt;\u2009110\/min: 3 [0\u201313], HR\u2009&lt;\u200950\/min: 0 [0\u20131], RF\u2009&gt;\u200924\/min: 1 [0\u20134] and RF\u2009&lt;\u200911\/min: 4 [2\u201312].\n                    <jats:italic>Sustained<\/jats:italic>\n                    episodes of severe desaturations, tachycardia and tachypnea were short, but moderate desaturations frequent. These findings indicate that vital signs in complication free patients should be carefully analyzed when monitored continuously after major surgery.\n                  <\/jats:p>","DOI":"10.1007\/s10877-026-01471-7","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T07:16:50Z","timestamp":1783754210000},"page":"1147-1154","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vital signs during complication-free recovery after major surgery: a retrospective analysis"],"prefix":"10.1007","volume":"40","author":[{"given":"Casper H.","family":"Guldager","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper","family":"M\u00f8lgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helle K.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian S.","family":"Meyhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eske K.","family":"Aasvang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,11]]},"reference":[{"key":"1471_CR1","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1097\/01.CCM.0000254826.10520.87","volume":"35","author":"BH Cuthbertson","year":"2007","unstructured":"Cuthbertson BH, Boroujerdi M, McKie L, Aucott L, Prescott G. 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WARD24\/7 ApS has obtained license agreement for any WARD-project software and patents. One patent has been filed: \u201cWireless Assessment of Respiratory and circulatory Distress (WARD), EP 21184712.4 and EP 21205557.8\u201d.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}