{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T11:44:36Z","timestamp":1784634276508,"version":"3.55.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T00:00:00Z","timestamp":1482883200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Fluoresc"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1007\/s10895-016-2015-9","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T04:11:16Z","timestamp":1482898276000},"page":"799-804","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A Water-Soluble Fluorescent Probe for SO2 Derivatives in Aqueous Solution and Serum Based on Phenanthroimidazole Dye"],"prefix":"10.1007","volume":"27","author":[{"given":"Yang","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuzhang","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiafeng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuonuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaibo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,12,28]]},"reference":[{"key":"2015_CR1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.lfs.2013.12.027","volume":"98","author":"X-B Wang","year":"2014","unstructured":"Wang X-B, Du J-B, Cui H (2014) Sulfur dioxide, a double-faced molecule in mammals. Life Sci 98:63\u201367","journal-title":"Life Sci"},{"key":"2015_CR2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/labinvest.2009.102","volume":"90","author":"Y Sun","year":"2010","unstructured":"Sun Y, Tian Y, Prabha M, Liu D, Chen S, Zhang R, Liu X, Tang C, Tang X, Jin H, Du J (2010) Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling. Lab Investig 90:68\u201382","journal-title":"Lab Investig"},{"key":"2015_CR3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ejphar.2015.06.044","volume":"764","author":"X-B Wang","year":"2015","unstructured":"Wang X-B, Du J-B, Cui H (2015) Signal pathways involved in the biological effects of sulfur dioxide. Eur J Pharmacol 764:94\u201399","journal-title":"Eur J Pharmacol"},{"key":"2015_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2458-12-1","volume":"12","author":"C-Y Tseng","year":"2012","unstructured":"Tseng C-Y, Huang Y-C, Su S-Y, Huang J-Y, Lai C-H, Lung C-C, Ho C-C, Liaw Y-P (2012) Cell type specificity of female lung cancer associated with sulfur dioxide from air pollutants in Taiwan: an ecological study. BMC Public Health 12:1\u20138","journal-title":"BMC Public Health"},{"key":"2015_CR5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2011.08.031","volume":"670","author":"X-B Wang","year":"2011","unstructured":"Wang X-B, Jin H-F, Tang C-S, Du J-B (2011) The biological effect of endogenous sulfur dioxide in the cardiovascular system. Eur J Pharmacol 670:1\u20136","journal-title":"Eur J Pharmacol"},{"key":"2015_CR6","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nchembio.69","volume":"4","author":"DW Domaille","year":"2008","unstructured":"Domaille DW, Que EL, Chang CJ (2008) Synthetic fluorescent sensors for studying the cell biology of metals. Nat Chem Biol 4:168\u2013175","journal-title":"Nat Chem Biol"},{"key":"2015_CR7","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.1039\/c1cs15028f","volume":"40","author":"JF Zhang","year":"2011","unstructured":"Zhang JF, Zhou Y, Yoon J, Kim JS (2011) Recent progress in fluorescent and colorimetric chemosensors for detection of precious metal ions (silver, gold and platinum ions). Chem Soc Rev 40:3416\u20133429","journal-title":"Chem Soc Rev"},{"key":"2015_CR8","doi-asserted-by":"crossref","first-page":"4619","DOI":"10.1039\/C4CS00275J","volume":"44","author":"J Yin","year":"2015","unstructured":"Yin J, Hu Y, Yoon J (2015) Fluorescent probes and bioimaging: alkali metals, alkaline earth metals and pH. Chem Soc Rev 44:4619\u20134644","journal-title":"Chem Soc Rev"},{"key":"2015_CR9","doi-asserted-by":"crossref","first-page":"13658","DOI":"10.1002\/anie.201510721","volume":"55","author":"W Xu","year":"2016","unstructured":"Xu W, Zeng Z, Jiang J-H, Chang Y-T, Yuan L (2016) Discerning the chemistry in individual organelles with small-molecule fluorescent probes. Angew Chem Int Ed 55:13658\u201313699","journal-title":"Angew Chem Int Ed"},{"key":"2015_CR10","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1039\/C4CS00285G","volume":"44","author":"H Zhu","year":"2015","unstructured":"Zhu H, Fan J, Wang B, Peng X (2015) Fluorescent, MRI, and colorimetric chemical sensors for the first-row d-block metal ions. Chem Soc Rev 44:4337\u20134366","journal-title":"Chem Soc Rev"},{"key":"2015_CR11","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s10895-005-0030-3","volume":"16","author":"A Gomes","year":"2006","unstructured":"Gomes A, Fernandes E, Lima JLFC (2006) Use of fluorescence probes for detection of reactive nitrogen species: a review. J Fluoresc 16:119\u2013139","journal-title":"J Fluoresc"},{"key":"2015_CR12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.snb.2010.09.066","volume":"152","author":"X-F Yang","year":"2011","unstructured":"Yang X-F, Zhao M, Wang G (2011) A rhodamine-based fluorescent probe selective for bisulfite anion in aqueous ethanol media. Sensors Actuators B 152:8\u201313","journal-title":"Sensors Actuators B"},{"key":"2015_CR13","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.snb.2012.03.034","volume":"166-167","author":"Y Yang","year":"2012","unstructured":"Yang Y, Huo F, Zhang J, Xie Z, Chao J, Yin C, Tong H, Liu D, Jin S, Cheng F, Yan X (2012) A novel coumarin-based fluorescent probe for selective detection of bissulfite anions in water and sugar samples. Sensors Actuators B 166-167:665\u2013670","journal-title":"Sensors Actuators B"},{"key":"2015_CR14","doi-asserted-by":"crossref","first-page":"8663","DOI":"10.1039\/C5OB00765H","volume":"13","author":"X Liu","year":"2015","unstructured":"Liu X, Yang Q, Chen W, Mo L, Chen S, Kang J, Song X (2015) A ratiometric fluorescent probe for rapid, sensitive and selective detection of sulfur dioxide with large stokes shifts by single wavelength excitation. Org Biomol Chem 13:8663\u20138668","journal-title":"Org Biomol Chem"},{"key":"2015_CR15","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.snb.2016.06.055","volume":"236","author":"L-J Zhang","year":"2016","unstructured":"Zhang L-J, Wang Z-Y, Cao X-J, Liu J-T, Zhao B-X (2016) An effective ICT-based and ratiometric fluorescent probe for sensing sulfite. Sensors Actuators B 236:741\u2013748","journal-title":"Sensors Actuators B"},{"key":"2015_CR16","doi-asserted-by":"crossref","first-page":"5624","DOI":"10.1021\/ol102298b","volume":"12","author":"MG Choi","year":"2010","unstructured":"Choi MG, Hwang J, Eor S, Chang S-K (2010) Chromogenic and fluorogenic signaling of sulfite by selective deprotection of resorufin levulinate. Org Lett 12:5624\u20135627","journal-title":"Org Lett"},{"key":"2015_CR17","doi-asserted-by":"crossref","first-page":"11935","DOI":"10.1021\/jf2032928","volume":"59","author":"X Gu","year":"2011","unstructured":"Gu X, Liu C, Zhu Y-C, Zhu Y-Z (2011) A boron-dipyrromethene-based fluorescent probe for colorimetric and ratiometric detection of sulfite. J Agric Food Chem 59:11935\u201311939","journal-title":"J Agric Food Chem"},{"key":"2015_CR18","doi-asserted-by":"crossref","first-page":"10869","DOI":"10.1039\/c2ra21471g","volume":"2","author":"S Chen","year":"2012","unstructured":"Chen S, Hou P, Wang J, Song X (2012) A highly sulfite-selective ratiometric fluorescent probe based on ESIPT. RSC Adv 2:10869\u201310873","journal-title":"RSC Adv"},{"key":"2015_CR19","doi-asserted-by":"crossref","first-page":"10381","DOI":"10.1039\/C6CC03910C","volume":"52","author":"S Samanta","year":"2016","unstructured":"Samanta S, Dey P, Ramesh A, Das G (2016) A solo fluorogenic probe for the real-time sensing of SO3 2\u2212 and SO4 2\u2212\/HSO4 \u2212 in aqueous medium and live cells by distinct turn-on emission signals. Chem Commun 52:10381\u201310384","journal-title":"Chem Commun"},{"key":"2015_CR20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2015.03.038","volume":"56","author":"W Xu","year":"2015","unstructured":"Xu W, Teoh CL, Peng J, Su D, Yuan L, Chang Y-T (2015) A mitochondria-targeted ratiometric fluorescent probe to monitor endogenously generated sulfur dioxide derivatives in living cells. Biomaterials 56:1\u20139","journal-title":"Biomaterials"},{"key":"2015_CR21","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1039\/C5CC10505F","volume":"52","author":"Y Liu","year":"2016","unstructured":"Liu Y, Li K, Xie K-X, Li L-L, Yu K-K, Wang X, Yu X-Q (2016) A water-soluble and fast-response mitochondria targeted fluorescent probe for colorimetric and ratiometric sensing of endogenously generated SO2 derivatives in living cells. Chem Commun 52:3430\u20133433","journal-title":"Chem Commun"},{"key":"2015_CR22","doi-asserted-by":"crossref","first-page":"33507","DOI":"10.1039\/C4RA05292G","volume":"4","author":"C Liu","year":"2014","unstructured":"Liu C, Liu L, Li X, Shao C, Huang X, Zhu B, Zhang X (2014) A highly selective colorimetric and far-red fluorescent probe for imaging bisulfite in living cells. RSC Adv 4:33507\u201333513","journal-title":"RSC Adv"},{"key":"2015_CR23","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1039\/c3cc39161b","volume":"49","author":"Y-Q Sun","year":"2013","unstructured":"Sun Y-Q, Liu J, Zhang J, Yang T, Guo W (2013) Fluorescent probe for biological gas SO2 derivatives bisulfite and sulfite. Chem Commun 49:2637\u20132639","journal-title":"Chem Commun"},{"key":"2015_CR24","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1021\/acs.analchem.6b00061","volume":"88","author":"Y Zhang","year":"2016","unstructured":"Zhang Y, Guan L, Yu H, Yan Y, Du L, Liu Y, Sun M, Huang D, Wang S (2016) Reversible fluorescent probe for selective detection and cell imaging of oxidative stress indicator bisulfite. Anal Chem 88:4426\u20134431","journal-title":"Anal Chem"},{"key":"2015_CR25","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1021\/acs.iecr.5b04530","volume":"55","author":"H Li","year":"2016","unstructured":"Li H, Yao Q, Fan J, Hu C, Xu F, Du J, Wang J, Peng X (2016) A fluorescent probe for ratiometric imaging of SO2 derivatives in mitochondria of living cells. Ind Eng Chem Res 55:1477\u20131483","journal-title":"Ind Eng Chem Res"},{"key":"2015_CR26","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.snb.2016.07.107","volume":"238","author":"M G\u00f3mez","year":"2017","unstructured":"G\u00f3mez M, Perez EG, Arancibia V, Iribarren C, Bravo-D\u00edaz C, Garc\u00eda-Beltr\u00e1n O, Aliaga ME (2017) New fluorescent turn-off probes for highly sensitive and selectivedetection of SO2 derivatives in a micellar media. Sensors Actuators B 238:578\u2013587","journal-title":"Sensors Actuators B"},{"key":"2015_CR27","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.aca.2016.07.017","volume":"937","author":"X Zhu","year":"2016","unstructured":"Zhu X, Zhu L, Liu H-W, Hu X, Peng R-Z, Zhang J, Zhang X-B, Tan W (2016) A two-photon fluorescent turn-on probe for imaging of SO2 derivatives in living cells and tissues. Anal Chim Acta 937:136\u2013142","journal-title":"Anal Chim Acta"},{"key":"2015_CR28","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1021\/acssensors.5b00165","volume":"1","author":"J Yang","year":"2016","unstructured":"Yang J, Li K, Hou J-T, Li L-L, Lu C-Y, Xie Y-M, Wang X, Yu X-Q (2016) Novel tumor-specific and mitochondria-targeted near-infrared-emission fluorescent probe for SO2 derivatives in living cells. ACS Sens 1:166\u2013172","journal-title":"ACS Sens"},{"key":"2015_CR29","doi-asserted-by":"crossref","first-page":"9683","DOI":"10.1039\/c2ob26956b","volume":"10","author":"K Zheng","year":"2012","unstructured":"Zheng K, Lin W, Tan L (2012) A phenanthroimidazole-based fluorescent chemosensor for imaging hydrogen sulfide in living cells. Org Biomol Chem 10:9683\u20139688","journal-title":"Org Biomol Chem"},{"key":"2015_CR30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.aca.2015.03.017","volume":"879","author":"B Gu","year":"2015","unstructured":"Gu B, Mi N, Zhang Y, Yin P, Li H, Yao S (2015) A tetraphenylimidazole-based fluorescent probe for the detection of hydrogen sulfide and its application in living cells. Anal Chim Acta 879:85\u201390","journal-title":"Anal Chim Acta"},{"key":"2015_CR31","doi-asserted-by":"crossref","first-page":"7429","DOI":"10.1016\/j.biomaterials.2013.06.013","volume":"34","author":"J Wang","year":"2013","unstructured":"Wang J, Lin W, Li W (2013) Three-channel fluorescent sensing via organic white light-emitting dyes for detection of hydrogen sulfide in living cells. Biomaterials 34:7429\u20137436","journal-title":"Biomaterials"},{"key":"2015_CR32","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.snb.2016.02.125","volume":"230","author":"J Hu","year":"2016","unstructured":"Hu J, Hu Z, Liu S, Zhang Q, Gao H-W, Uvdal K (2016) A new ratiometric fluorescent chemodosimeter based on an ICT modulation for the detection of Hg2+. Sensors Actuators B 230:639\u2013644","journal-title":"Sensors Actuators B"},{"key":"2015_CR33","first-page":"1676","volume":"79","author":"Y Yan","year":"2014","unstructured":"Yan Y, Zhang R, Yu X, Xu H (2014) A selective and sensitive phenanthroimidazole-based\u201creactive\u201dratiometric sensor for recognition of Hg2+ ions in aqueous solution. Chem Plus Chem 79:1676\u20131680","journal-title":"Chem Plus Chem"},{"key":"2015_CR34","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1039\/C5AN00273G","volume":"140","author":"B Gu","year":"2015","unstructured":"Gu B, Huang L, Mi N, Yin P, Zhang Y, Tu X, Luo X, Luo S, Yao S (2015) An ESIPT-based fluorescent probe for highly selective and ratiometric detection of mercury (II) in solution and in cells. Analyst 140:2778\u20132784","journal-title":"Analyst"},{"key":"2015_CR35","doi-asserted-by":"crossref","first-page":"67849","DOI":"10.1039\/C5RA09536K","volume":"5","author":"AJ Beneto","year":"2015","unstructured":"Beneto AJ, Thiagarajan V, Siva A (2015) A tunable ratiometric pH sensor based on phenanthro[9,10-d]imidazole covalently linked with vinylpyridine. RSC Adv 5:67849\u201367852","journal-title":"RSC Adv"},{"key":"2015_CR36","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.snb.2012.09.049","volume":"176","author":"KC Song","year":"2013","unstructured":"Song KC, Kim H, Lee KM, Lee YS, Do Y, Lee MH (2013) Ratiometric fluorescence sensing of fluoride ions by triarylborane-phenanthroimidazole conjugates. Sensors Actuators B 176:850\u2013857","journal-title":"Sensors Actuators B"},{"key":"2015_CR37","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1039\/c3ay26461k","volume":"5","author":"T Li","year":"2013","unstructured":"Li T, Yu L, Jin D, Chen B, Li L, Chen L, Li Y (2013) A colorimetric and fluorescent probe for fluoride anions based on a phenanthroimidazole-cyanine platform. Anal Methods 5:1612\u20131616","journal-title":"Anal Methods"},{"key":"2015_CR38","doi-asserted-by":"crossref","first-page":"37935","DOI":"10.1039\/C5RA05327G","volume":"5","author":"AK Mahapatra","year":"2015","unstructured":"Mahapatra AK, Karmakar P, Roy J, Manna S, Maiti K, Sahoo P, Mandal D (2015) Colorimetric and ratiometric fluorescent chemosensor for fluoride ions based on phenanthroimidazole (PI): spectroscopic, NMR and density functional studies. RSC Adv 5:37935\u201337942","journal-title":"RSC Adv"},{"key":"2015_CR39","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1002\/chem.200801501","volume":"15","author":"W Lin","year":"2009","unstructured":"Lin W, Yuan L, Tan W, Feng J, Long L (2009) Construction of fluorescent probes via protection\/deprotection of functional groups: a ratiometric fluorescent probe for Cu2+. Chem Eur J 15:1030\u20131035","journal-title":"Chem Eur J"}],"container-title":["Journal of Fluorescence"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10895-016-2015-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10895-016-2015-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10895-016-2015-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T06:54:07Z","timestamp":1498373647000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10895-016-2015-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,28]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["2015"],"URL":"https:\/\/doi.org\/10.1007\/s10895-016-2015-9","relation":{},"ISSN":["1053-0509","1573-4994"],"issn-type":[{"value":"1053-0509","type":"print"},{"value":"1573-4994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,28]]}}}