{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T03:30:55Z","timestamp":1778211055395,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,12,29]],"date-time":"2005-12-29T00:00:00Z","timestamp":1135814400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Women at greatest risk for hereditary breast and ovarian cancer may consider prophylactic removal of breasts or ovaries as a risk\u2010reduction measure. This report describes uptake of risk\u2010reduction mastectomy (RRM), risk\u2010reduction oophorectomy (RRO), and related factors in 62 high\u2010risk women who received genetic counseling. Seven (11%) participants underwent RRM and 13 (21%) underwent RRO. Of these women, 37% did not have BRCA testing, suggesting other factors influence decisions to undergo surgery. Women who had indicated (pre\u2010genetic counseling) their intent not to have surgery chose not to have surgery. Information received during genetic counseling that women perceived as being <jats:italic>most<\/jats:italic> important for influencing risk\u2010reduction surgery decisions was BRCA test result (positive or negative), followed by discussion of family cancer history. Reasons for indecision about risk\u2010reduction surgery included genetic testing results, concerns about surgery, timing in life, and early menopause. The findings enhance our understanding of information that is helpful to women considering this surgery.<\/jats:p>","DOI":"10.1007\/s10897-005-5833-5","type":"journal-article","created":{"date-parts":[[2005,12,30]],"date-time":"2005-12-30T16:08:57Z","timestamp":1135958937000},"page":"473-484","source":"Crossref","is-referenced-by-count":41,"title":["Risk\u2010Reduction Surgery Decisions in High\u2010Risk Women Seen for Genetic Counseling"],"prefix":"10.1002","volume":"14","author":[{"given":"Jessica A.","family":"Ray","sequence":"first","affiliation":[{"name":"Arizona Cancer Center University of Arizona Tucson AZ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lois J.","family":"Loescher","sequence":"additional","affiliation":[{"name":"Arizona Cancer Center University of Arizona Tucson AZ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly","family":"Brewer","sequence":"additional","affiliation":[{"name":"Arizona Cancer Center University of Arizona Tucson AZ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,29]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.06.090"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8545(01)00004-3"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199107000-00007"},{"key":"e_1_2_1_5_1","first-page":"232","article-title":"Genetic analysis of breast cancer in the cancer and steroid hormone study","volume":"48","author":"Claus E. 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