{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:33:16Z","timestamp":1760981596371},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,11,15]],"date-time":"2006-11-15T00:00:00Z","timestamp":1163548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>This article presents and discusses four clinical cases that exemplify the complexity of ethical dilemmas concerning the provider's obligation to disclose or withhold genetic information from patients.<\/jats:p><jats:p>Case 1: What is the responsibility of the cancer genetics provider to ensure that a positive test results is shared with distant relatives?<\/jats:p><jats:p>Case 2: To ensure that results go to at\u2010risk relatives, do we have the right to ignore the wishes of the designated next\u2010of\u2010kin?<\/jats:p><jats:p>Case 3: Do we have the right to reveal a familial <jats:italic>BRCA1<\/jats:italic> mutation to a patient's relative, who is at 50% risk?<\/jats:p><jats:p>Case 4: Do we have an obligation to reveal that a patient is not a blood relative and therefore, not at risk to have inherited a familial mutation?<\/jats:p><jats:p>These cases form the basis for discussing the provider's dual obligations to keeping patient confidentiality and informing patients and families about risk (i.e. duty to warn). We also provide a summary of consensus points and additional discussion questions for each case.<\/jats:p>","DOI":"10.1007\/s10897-006-9053-4","type":"journal-article","created":{"date-parts":[[2006,11,14]],"date-time":"2006-11-14T16:24:34Z","timestamp":1163521474000},"page":"491-503","source":"Crossref","is-referenced-by-count":12,"title":["Ethical Issues in Cancer Genetics: 1) Whose Information Is It?"],"prefix":"10.1002","volume":"15","author":[{"given":"Katherine A.","family":"Schneider","sequence":"first","affiliation":[{"name":"Department of Adult Oncology Dana\u2010Farber Cancer Institute 44 Binney Street, SM331 Boston MA 02115 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anu B.","family":"Chittenden","sequence":"additional","affiliation":[{"name":"Department of Adult Oncology Dana\u2010Farber Cancer Institute 44 Binney Street, SM331 Boston MA 02115 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly J.","family":"Branda","sequence":"additional","affiliation":[{"name":"Department of Adult Oncology Dana\u2010Farber Cancer Institute 44 Binney Street, SM331 Boston MA 02115 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith A.","family":"Keenan","sequence":"additional","affiliation":[{"name":"Department of Adult Oncology Dana\u2010Farber Cancer Institute 44 Binney Street, SM331 Boston MA 02115 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Joffe","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology Dana\u2010Farber Cancer Institute Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Farkas","family":"Patenaude","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology Dana\u2010Farber Cancer Institute Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazel","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of MO\u2010HM Dana\u2010Farber Cancer Institute Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Dent","sequence":"additional","affiliation":[{"name":"University of Utah Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Eubanks","sequence":"additional","affiliation":[{"name":"University of North Carolina Greensboro\/Genetic Counseling Program Greensboro NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Goldman","sequence":"additional","affiliation":[{"name":"University of California San Francisco Memory &amp; 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