{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T06:47:58Z","timestamp":1781938078800,"version":"3.54.5"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,4,10]],"date-time":"2009-04-10T00:00:00Z","timestamp":1239321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A decade of genetic counseling of frontotemporal dementia (FTD) affected families has generated two important observations. First, the uptake rate for presymptomatic testing for FTD is low in our department of Clinical Genetics at the Erasmus Medical Center in the Netherlands. Second, FTD at\u2010risk counselees reported substantial familial opposition to genetic testing, which is distinct from the attitude in Huntington Disease affected families. We hypothesize that the low acceptance for FTD genetic counseling is consequential to the familial opposition and explain this within the theoretical framework of separation\u2010individuation. Furthermore, we hypothesize that separation\u2010individuation problems do not similarly influence the acceptance of HD genetic counseling, due to the educative role of the well\u2010organised patient organization for HD in the Netherlands. We offer counseling recommendations that serve to facilitate the individuation of the counselee with respect to the FTD genetic test.<\/jats:p>","DOI":"10.1007\/s10897-009-9222-3","type":"journal-article","created":{"date-parts":[[2009,4,9]],"date-time":"2009-04-09T20:40:20Z","timestamp":1239309620000},"page":"350-356","source":"Crossref","is-referenced-by-count":28,"title":["A Decade of Genetic Counseling in Frontotemporal Dementia Affected Families: Few Counseling Requests and much Familial Opposition to Testing"],"prefix":"10.1002","volume":"18","author":[{"given":"S. R.","family":"Riedijk","sequence":"first","affiliation":[{"name":"Department of Clinical Genetics Erasmus Medical Centre Westzeedijk 112 Rotterdam 3016 AH The Netherlands"},{"name":"Department of Medical Psychology and Psychotherapy Erasmus Medical Centre Rotterdam Section of Clinical Genetics Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. F. N.","family":"Niermeijer","sequence":"additional","affiliation":[{"name":"Department Anthropogenetics University Medical Centre Nijmegen\u2013St. Radboud Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Dooijes","sequence":"additional","affiliation":[{"name":"Dept of Clinical Genetics VU University Medical Center Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tibben","sequence":"additional","affiliation":[{"name":"Centre of Human and Clinical Genetics, and Department Neurology LUMC Leiden Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,4,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0743554897121002"},{"key":"e_1_2_7_3_1","first-page":"162","volume-title":"The psychoanalytic study of the child","author":"Blos P.","year":"1967"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20000814)93:4<257::AID-AJMG1>3.0.CO;2-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201772"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1545-5300.2002.00677.x"},{"key":"e_1_2_7_7_1","volume-title":"The expanded family life cycle, individual, family and social perspectives","author":"Carter B.","year":"2005"},{"key":"e_1_2_7_8_1","first-page":"105","article-title":"Adolescent separation\u2010individuation and family transitions","volume":"25","author":"Daniels J. A.","year":"1990","journal-title":"Adolescence"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5200913"},{"key":"e_1_2_7_10_1","first-page":"A9","article-title":"Childhood experiences with a parent with a hereditary late onset disease and the impact on wellbeing: a new direction in research","volume":"37","author":"Duisterhof M.","year":"2000","journal-title":"Journal of Medical Genetics"},{"key":"e_1_2_7_11_1","first-page":"315","article-title":"Are experiences with HD related to the attachment representation in adults at 50% risk for HD? An empirical exploration","volume":"10","author":"Duisterhof M.","year":"2002","journal-title":"European Journal of Human Genetics"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970711)71:1<22::AID-AJMG4>3.0.CO;2-S"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.nrl.0000138735.48533.26"},{"key":"e_1_2_7_14_1","first-page":"82","article-title":"Individuation in family relationships. A perspective on individual differences in the development of identity and role\u2010taking skill in adolescence","volume":"29","author":"Grootevant H. D.","year":"1986","journal-title":"Human Development"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410205"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.69.5.579"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00797308.1963.11822933"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.150.3.319"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1545-5300.2005.00040.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000334277.16896.fa"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.73.5.1092"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-6427.00144"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70221-1"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn257"},{"key":"e_1_2_7_25_1","first-page":"139","volume-title":"Individuals, families, and the New Era of Genetics: Biopsychosocial Perspectives","author":"Rolland J.","year":"2006"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1545-5300.1987.00203.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg204"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000319702.37497.72"},{"key":"e_1_2_7_29_1","first-page":"700","article-title":"Molecular pathogenesis of frontotemporal lobar degeneration: basic science seminar in neurology","volume":"6","author":"Sleegers K.","year":"2008","journal-title":"Archives of Neurology"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.2.140"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2006.10.023"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.5.400"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2005.11.019"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000327523.52537.86"},{"key":"e_1_2_7_35_1","first-page":"365","article-title":"De missing link tussen trauma en borderline problematiek. Een benadering vanuit de hechtingsproblematiek","volume":"28","author":"Gael M.","year":"2002","journal-title":"Tijdschrift voor Psychotherapie"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70194-7"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70224-7"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1159\/000077150"},{"key":"e_1_2_7_39_1","first-page":"1","volume-title":"New directions for child development, vol. 22: Adolescent development in the family","author":"White K. M.","year":"1983"}],"container-title":["Journal of Genetic Counseling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10897-009-9222-3","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1007\/s10897-009-9222-3","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10897-009-9222-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T04:25:05Z","timestamp":1694751905000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s10897-009-9222-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,10]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1007\/s10897-009-9222-3"],"URL":"https:\/\/doi.org\/10.1007\/s10897-009-9222-3","archive":["Portico"],"relation":{},"ISSN":["1059-7700","1573-3599"],"issn-type":[{"value":"1059-7700","type":"print"},{"value":"1573-3599","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,10]]}}}