{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:34:30Z","timestamp":1791016470739,"version":"4.1.0"},"reference-count":62,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,5,29]],"date-time":"2009-05-29T00:00:00Z","timestamp":1243555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012400","name":"Sigma Theta Tau International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012400","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Discovery of mutations in the breast and ovarian cancer susceptibility genes\n                    <jats:italic>BRCA1<\/jats:italic>\n                    and\n                    <jats:italic>BRCA2<\/jats:italic>\n                    can have emotional consequences for both the tested individual and his or her relatives. This secondary analysis study investigated how\n                    <jats:italic>BRCA<\/jats:italic>\n                    testing impacts family dynamics and relationships. For the original study, a grounded theory inquiry, participants were recruited from a hereditary breast\/ovarian cancer syndrome support website and open\u2010ended interviews were performed asking about individual and family experiences after\n                    <jats:italic>BRCA<\/jats:italic>\n                    testing. All 12 participants whose interviews were included in the secondary analysis had a\n                    <jats:italic>BRCA<\/jats:italic>\n                    mutation. For the secondary analysis, thematic analysis was conducted and revealed three main themes characterizing the effect of\n                    <jats:italic>BRCA<\/jats:italic>\n                    testing on family relationships: 1. That the first in the family to have testing or seek genetic counseling takes on a special family role that can be difficult for them; 2. That discussions in the family often change; and 3. That individuals may feel more or less connected to certain family members. These changes seemed to relate to family cancer history, relationships, coping strategies, communication patterns, and mutation status. Genetic counselors might find it useful to explore these issues in order to prepare clients before\n                    <jats:italic>BRCA<\/jats:italic>\n                    testing and to support them through shifts in family dynamics after disclosure of results.\n                  <\/jats:p>","DOI":"10.1007\/s10897-009-9232-1","type":"journal-article","created":{"date-parts":[[2009,5,28]],"date-time":"2009-05-28T11:18:05Z","timestamp":1243509485000},"page":"418-435","source":"Crossref","is-referenced-by-count":68,"title":["The Effect of BRCA Gene Testing on Family Relationships: A Thematic Analysis of Qualitative Interviews"],"prefix":"10.1002","volume":"18","author":[{"given":"Heather A.","family":"Douglas","sequence":"first","affiliation":[{"name":"Centenary Site Rouge Valley Health System 4th floor Genetics Clinic, 2867 Ellesmere Road Toronto ON M1E 4B9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah J.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Women, Children and Family Health Sciences University of Illinois at Chicago Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin E.","family":"Grubs","sequence":"additional","affiliation":[{"name":"Department of Human Genetics University of Pittsburgh Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,5,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369-7625.2008.00494.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025659701805"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/109065703322537241"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.1900"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2354.1998.00094.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-007-9117-0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.10868"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.10003"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-8519.00234"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2006.00720.x"},{"key":"e_1_2_6_13_1","first-page":"393","article-title":"Exploring family relationships in cancer risk counseling using the genogram","volume":"8","author":"Daly M.","year":"1999","journal-title":"Cancer Epidemiology, Biomarkers & Prevention"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003727-200110000-00004"},{"key":"e_1_2_6_15_1","first-page":"38","volume-title":"The nursing of families: Theory\/research\/education\/practice","author":"Deatrick J. 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