{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:33:54Z","timestamp":1788176034396,"version":"build-2803163510"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,1,26]],"date-time":"2012-01-26T00:00:00Z","timestamp":1327536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Huntington disease (HD) includes a prodromal phase with behavioral, cognitive, and motor function decline occurring up to 15 years prior to diagnosis. This study used mixed methods to examine how people in the prodromal phase and their companions coped with noticed changes. Twenty\u2010three couples completed a semi\u2010structured interview and Brief COPE. Participants with prodromal HD used acceptance, emotional support, and planning most frequently; companions used acceptance, planning, and active coping. Least frequently used coping strategies for each were denial, behavioral disengagement, and substance use. Qualitative interviews revealed coping strategies not included in the Brief COPE. Participants with prodromal HD used prescription medications, coping as a couple, hope, and self\u2010monitoring; companions used hope and helping their partners. Many of the coping procedures were rated as effective, especially when changes were not severe. Couples may benefit from counseling that emphasizes using active coping strategies for changes that can be compensated for and acceptance for changes that cannot in prodromal HD. Findings from this study may be helpful for counseling patients and significant others facing other neurodegenerative conditions with prodromal or early phases, such as Alzheimer disease and Parkinson disease.<\/jats:p>","DOI":"10.1007\/s10897-012-9480-3","type":"journal-article","created":{"date-parts":[[2012,1,26]],"date-time":"2012-01-26T05:28:40Z","timestamp":1327555720000},"page":"662-670","source":"Crossref","is-referenced-by-count":14,"title":["Couples\u2019 Coping in Prodromal Huntington Disease: A Mixed Methods Study"],"prefix":"10.1002","volume":"21","author":[{"given":"Nancy R.","family":"Downing","sequence":"first","affiliation":[{"name":"The University of Iowa College of Nursing Iowa City IA 52242 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet K.","family":"Williams","sequence":"additional","affiliation":[{"name":"The University of Iowa College of Nursing Iowa City IA 52242 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne L.","family":"Leserman","sequence":"additional","affiliation":[{"name":"The University of Iowa Carver College of Medicine Research, 1\u2010305 Medical Education Building Iowa City IA 52242\u20101000 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane S.","family":"Paulsen","sequence":"additional","affiliation":[{"name":"The University of Iowa Carver College of Medicine Research, 1\u2010305 Medical Education Building Iowa City IA 52242\u20101000 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6811.2004.00078.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200101000-00004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.133.6.920"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22601"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327558ijbm0401_6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.56.2.267"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320540303"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066X.55.6.637"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.11.004"},{"issue":"3","key":"e_1_2_6_11_1","first-page":"209","article-title":"Clarifying the concept of normalization","volume":"31","author":"Deatrick J. A.","year":"1999","journal-title":"Image"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-010-9294-0"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181eccfa2"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2010.22.2.196"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1348\/135910702320645417"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15327558IJBM0901_03"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22412"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-003-0003-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732305276687"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-007-9194-4"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6811.1999.tb00202.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2004.00241.x"},{"key":"e_1_2_6_23_1","volume-title":"Stress and emotion.","author":"Lazarus R. S.","year":"1999"},{"key":"e_1_2_6_24_1","volume-title":"Stress, appraisal, and coping.","author":"Lazarus R. S.","year":"1984"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870449808407425"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1348\/135910706X118422"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-6-38"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701400276"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012731520781"},{"key":"e_1_2_6_30_1","volume-title":"Mixed method design: Principles and procedures.","author":"Morse J. M.","year":"2009"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.2307\/584977"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548500410001721936"},{"key":"e_1_2_6_33_1","volume-title":"Qualitative research and evaluation methods","author":"Patton M. Q.","year":"2002"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.2217\/fnl.09.78"},{"key":"e_1_2_6_35_1","volume-title":"NVivo8.","author":"QSR International","year":"2007"},{"key":"e_1_2_6_36_1","volume-title":"Huntington's disease.","author":"Quarrell O.","year":"2008"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/104973239300300102"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.4770180211"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-240X(200008)23:4<334::AID-NUR9>3.0.CO;2-G"},{"key":"e_1_2_6_40_1","unstructured":"SPSS I.(2009).PASW statistics developer."},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0020937"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70276-3"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15327957PSPR0601_1"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-240X(199704)20:2<169::AID-NUR9>3.0.CO;2-I"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2006.10.023"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.5.400"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.44.1.51"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60111-1"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30479"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2214.2007.00804.x"}],"container-title":["Journal of Genetic Counseling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10897-012-9480-3","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1007\/s10897-012-9480-3","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s10897-012-9480-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:02:46Z","timestamp":1694736166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s10897-012-9480-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,26]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1007\/s10897-012-9480-3"],"URL":"https:\/\/doi.org\/10.1007\/s10897-012-9480-3","archive":["Portico"],"relation":{},"ISSN":["1059-7700","1573-3599"],"issn-type":[{"value":"1059-7700","type":"print"},{"value":"1573-3599","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,26]]}}}