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As an initial step toward the implementation of genomic\u2010based medicine, we explored primary care patients\u2019 ideas about genomic testing for common complex diseases to help develop future patient education materials and interventions to communicate genomic risk information. We conducted a mixed\u2010methods study with participants from a large primary care clinic. Within four focus groups, we used a semi\u2010structured discussion guide and administered brief pre\u2010 and post\u2010 discussion quantitative surveys to assess participants\u2019 interest, attitudes, and preferences related to testing and receipt of test results. Prior to the discussion, moderators presented a plain\u2010language explanation of DNA and genetics, defined \u201cSNP\u201d, and highlighted what is known and unknown about the risks associated with testing for SNPs related to colorectal cancer risk. We used the NVIVO 8 software package to analyze the transcripts from the focus group discussions. The majority of participants (75 %) were \u201cvery\u201d or \u201csomewhat interested\u201d in receiving information from a colon cancer SNP test, even after learning about and discussing the small and still clinically uncertain change in risk conferred by SNPs. Reported interest in testing was related to degree of risk conferred, personal risk factors, family history, possible implications for managing health \/disease prevention and curiosity about genetic results. Most people (85 %) preferred that genetic information be delivered in person by a healthcare or genetics professional rather than through print materials or a computer. These findings suggest that patients may look to genetic counselors, physicians or other healthcare professionals as gatekeepers of predictive genomic risk information.<\/jats:p>","DOI":"10.1007\/s10897-012-9530-x","type":"journal-article","created":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T15:19:21Z","timestamp":1345562361000},"page":"138-151","source":"Crossref","is-referenced-by-count":30,"title":["\u201cIs it Really Worth it to Get Tested?\u201d: Primary Care Patients\u2019 Impressions of Predictive SNP Testing for Colon Cancer"],"prefix":"10.1002","volume":"22","author":[{"given":"Kara\u2010Grace","family":"Leventhal","sequence":"first","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Tuong","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth N.","family":"Peshkin","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Salehizadeh","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary B.","family":"Fishman","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine Georgetown University Hospital Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Eggly","sequence":"additional","affiliation":[{"name":"Department of Oncology, Karmanos Cancer Institute Wayne State University Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"FitzGerald","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc D.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristi D.","family":"Graves","sequence":"additional","affiliation":[{"name":"Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center Georgetown University 3300 Whitehaven Street, NW, Suite 4100 Washington DC 20007 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,8,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4603(97)00060-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000328846"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-011-1046-1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011893"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12687-010-0023-z"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genom.5.061903.180029"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.14.1682"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15324796abm3301_3"},{"key":"e_1_2_9_11_1","unstructured":"Chanock S. 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