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When individuals present for predictive testing while experiencing such symptoms, clinicians including genetic counselors, must proceed with caution and evaluate each situation on a case\u2010by\u2010case basis. Legitimate reasons may exist for moving forward with testing. Additionally predicting the consequences of testing is unrealistic so that the clinicians must do their best to prepare patients for both positive and negative results. A multidisciplinary team following the Huntington disease protocol remains the gold standard care for predictive testing for such patients. We discuss 3 case histories that demonstrate the complex nature of genetic counseling and testing in the presence of psychiatric symptoms, whether emanating from the disease itself or the results of living in an affected family.<\/jats:p>","DOI":"10.1007\/s10897-016-0056-5","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T23:55:55Z","timestamp":1482623755000},"page":"435-441","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Confluence of Psychiatric Symptoms and Neurodegenerative Disease: Impact on Genetic Counseling"],"prefix":"10.1002","volume":"26","author":[{"given":"Jill S.","family":"Goldman","sequence":"first","affiliation":[{"name":"Taub Institute Columbia University Medical Center Box 16, 630 W. 168th St. New York NY 10032 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward 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