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While a lot of attention is now given to pre\u2010test counselling procedures for WES, little is known about how parents experience the (positive, negative, or inconclusive) WES results in daily life. To fill this knowledge gap, data were gathered through in\u2010depth interviews with parents of 15 children who underwent WES analysis. WES test results, like results from other genetic tests, evoked relief as well as worries, irrespective of the type of result. Advantages of obtaining a conclusive diagnosis included becoming more accepting towards the situation, being enabled to attune care to the needs of the child, and better coping with feelings of guilt. Disadvantages experienced included a loss of hope for recovery, and a loss by parents of their social network of peers and the effort necessary to re\u2010establish that social network. While parents with conclusive diagnoses were able to re\u2010establish a peer community with the help of social media, parents receiving a possible diagnosis experienced hurdles in seeking peer support, as peers still needed to be identified. These types of psychosocial effects of WES test results for parents are important to take into account for the development of successful genetic counselling strategies.<\/jats:p>","DOI":"10.1007\/s10897-016-9958-5","type":"journal-article","created":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T01:29:44Z","timestamp":1461115784000},"page":"1207-1214","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Understanding the Psychosocial Effects of WES Test Results on Parents of Children with Rare Diseases"],"prefix":"10.1002","volume":"25","author":[{"given":"Lotte","family":"Krabbenborg","sequence":"first","affiliation":[{"name":"Radboud Institute for Health Sciences Radboud University Medical Center Nijmegen the Netherlands"},{"name":"Institute for Science, Innovation and Society (ISIS) Radboud University P.O. Box 9010 Nijmegen 6500 the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. E. L. M.","family":"Vissers","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, Donders Centre for Neuroscience Radboudumc Geert Grooteplein 10 Nijmegen 6525 the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schieving","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Kleefstra","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, Donders Centre for Neuroscience Radboudumc Geert Grooteplein 10 Nijmegen 6525 the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. 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A.","family":"Willemsen","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Van der Burg","sequence":"additional","affiliation":[{"name":"Radboud Institute for Health Sciences Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2013.145"},{"key":"e_1_2_11_3_1","volume-title":"Analyseren in Kwalitatief Onderzoek. Denken en Doen","author":"Boeije H.","year":"2012"},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","unstructured":"Bosma A. R. Rigter T. Weinreich S. S. Cornel M. 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