{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:09:07Z","timestamp":1780463347912,"version":"3.54.1"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:00:00Z","timestamp":1521849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:00:00Z","timestamp":1521849600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Guidelines recommend that African Americans know their sickle cell trait status to inform reproductive health decisions. Few studies have applied a behavioral theory to identify factors associated with sickle cell trait screening to inform intervention targets to increase this behavior. We applied a <jats:italic>Sickle Cell Trait Screening Framework<\/jats:italic> to identify factors associated with African Americans\u2019 intention <jats:italic>to ask for sickle cell trait screening<\/jats:italic>. Participants (<jats:italic>N<\/jats:italic>\u2009=\u2009300), ages 18 to 35, completed a cross\u2010sectional survey. A three\u2010step sequential ordinary least squares regression analysis identified factors influencing intention. Results indicated socio\u2010demographic factors (age, education), knowledge and fear beliefs (screening knowledge, perceived threat), and reasoned action approach (RAA) constructs were associated with intention. RAA constructs influenced intention over knowledge and fear beliefs with an increase in <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> of .468. Perceived behavioral control was more predictive of intention (\u03b2\u2009=\u2009.576, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Attitude and perceived norm also had significant weights (\u03b2\u2009=\u2009.325 and \u03b2\u2009=\u2009.192, both <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001, respectively). Findings from this study can inform strategies (e.g., eliminating costs associated with screening, reducing fear of painful tests) to increase sickle cell trait screening among African Americans. Ultimately, more sickle cell carriers will become aware of their trait status and be able to make informed reproductive health decisions.<\/jats:p>","DOI":"10.1007\/s10897-018-0255-3","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T23:32:19Z","timestamp":1521934339000},"page":"1302-1311","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Identifying Factors Underlying the Decision for Sickle Cell Carrier Screening Among African Americans Within Middle Reproductive Age"],"prefix":"10.1002","volume":"27","author":[{"given":"Tilicia L.","family":"Mayo\u2010Gamble","sequence":"first","affiliation":[{"name":"Department of Community Health Behavior and Education Georgia Southern University P.O. 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Todd Jr. Blvd. Nashville TN 37208 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla","family":"Barnes","sequence":"additional","affiliation":[{"name":"Department of Applied Health Science Indiana University 1025 E. 7th St. Bloomington IN 47405 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela Braboy","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Sociology Indiana University 1020 E. Kirkwood Ave. Bloomington IN 47405 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,24]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-9684(15)31113-5"},{"issue":"1","key":"e_1_2_13_3_1","first-page":"45","article-title":"Breast cancer education, selfefficacy, and screening in older African American women","volume":"9","author":"Adderley\u2010Kelly B.","year":"1997","journal-title":"Journal of National Black Nurses' Association"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1348\/014466601164939"},{"issue":"1","key":"e_1_2_13_5_1","first-page":"62","article-title":"Inadequate community knowledge about sickle cell disease among African\u2010American women","volume":"97","author":"Boyd J. 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