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However, the behaviour remains understudied, particularly, among rural-dwelling young people in countries within the subregion. We aimed to\u00a0estimate the 12\u00a0months prevalence of problem gambling and to describe\u00a0the overall and gender differences and commonalities in personal factors and social adversities associated with problem gambling among adolescents in rural Ghana. We conducted a cross-sectional survey involving a random sample of 1101 in-school adolescents aged 10\u201319\u00a0years in a rural district in Eastern Ghana; we used the DSM-IV-Multiple Response-Juvenile (DSM-IV-MR-J) questionnaire to assess problem gambling during the previous 12\u00a0months. Personal lifestyle and psychosocial variables were assessed using adopted items from the 2012 WHO\u2013Global School-based Student Health Survey. Overall, three in 10 adolescents (3 in 10 females; 4 in 10 males) in rural Ghana reported problem gambling in the previous 12\u00a0months. Female adolescents who experienced problem gambling were more likely to report family-related social adversities, while adolescent male problem gambling was associated with school-related factors and interpersonal factors outside the family context. Regardless of gender, sexual abuse victimisation was associated with three times increase in the odds of experiencing problem gambling. Relative to the prevalence of gambling among adolescents in urban contexts in other countries within sub-Saharan Africa, the estimates of problem gambling among in-school rural adolescents in Ghana are higher. Although further studies are needed to understand the nuances of the behaviour, the evidence of this study underscores the need for general and targeted health promotion, intervention and prevention efforts to mitigate the family, school, and interpersonal social adversities associated with adolescent problem gambling in rural Ghana.<\/jats:p>","DOI":"10.1007\/s10899-020-09987-6","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T18:02:41Z","timestamp":1605117761000},"page":"83-105","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Adolescent Problem Gambling in Rural Ghana: Prevalence and Gender Differentiation"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3292-537X","authenticated-orcid":false,"given":"Samuel Kofi","family":"Odame","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8720-2355","authenticated-orcid":false,"given":"Emmanuel Nii-Boye","family":"Quarshie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5892-9021","authenticated-orcid":false,"given":"Mabel","family":"Oti-Boadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7036-1835","authenticated-orcid":false,"given":"Johnny","family":"Andoh-Arthur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-3326","authenticated-orcid":false,"given":"Kwaku Oppong","family":"Asante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"9987_CR1","unstructured":"Aasved, M. 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