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KY, EK, SM, and RS received grants from the Ministry of Health, Labor and Welfare in Japan during the conduction of the study. KY received personal fees from a for-profit company promoting integrated resorts in Japan and abroad, domestic tobacco companies, and Cureapp. KY received research grants from the Japan Society for the Promotion of Science (JSPS). SM has received a research grant from Asahi. Quality & Innovations, Ltd. and speaker\u2019s honoraria from Otsuka Pharmaceutical, Eisai, and Nippon Shinyaku Co., Ltd. within the past three years. RS has received research grants from the JSPS, the Japan Agency for Medical Research and Development, the Osake-no-Kagaku Foundation, the The Mental Health Okamoto Memorial Foundation, and the Kobayashi Magobe Memorial Medical Foundation, as well as speaker\u2019s honoraria from Otsuka Pharmaceutical Co., Ltd., Nippon Shinyaku Co., Ltd., and Takeda Pharmaceutical Co., Ltd., outside the submitted work. RS also reports an employment position at, and a stock option from CureApp Inc., which develops software for medical devices. Other authors have nothing to disclose","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This study was approved by the institutional review board of Okayama Psychiatric Medical Center.\u00a0The study was registered with UMIN (000040003) prior to participant recruitment.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}