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Chitnis, Ramsey Cheung declares that they have no conflict of interest. Robert G. Gish\u2014consulting, advisor\u2014Abbot, AbbVie, Alexion, Arrowhead, Bayer AG, Biocollections, Bristol-Myers Squibb Company, Eiger, Enyo, eStudySite, Genentech, Gilead Sciences, HepaTX, HepQuant, Hoffmann-LaRoche Ltd., Intellia, Intercept, Ionis Pharmaceuticals, Janssen, MedImmune, Merck, Prometheus, Quest, Shionogi, Transgene, Trimaran. Scientific\/clinical advisory boards\u2014AbbVie, Merck, Arrowhead, Bayer, Dova Pharmaceuticals, Eiger, Enyo, Janssen, Medimmune, Janssen\/J&J, Intercept, Shionogi, Spring Bank. Clinical trials\u2014eStudySite. Chair clinical advisory board\u2014Arrowhead. Data safety monitoring board\u2014Ionis. Speaker\u2019s bureau \u2013 AbbVie, Alexion, Bayer, BMS, Gilead Sciences Inc., Merck. Robert J. 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