{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:48:50Z","timestamp":1790016530608,"version":"4.0.1"},"reference-count":365,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mammary Gland Biol Neoplasia"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s10911-021-09506-2","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T10:02:42Z","timestamp":1643191362000},"page":"419-453","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Colostrogenesis: Role and Mechanism of the Bovine Fc Receptor of the Neonate (FcRn)"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0862-7855","authenticated-orcid":false,"given":"Craig R.","family":"Baumrucker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7373-2737","authenticated-orcid":false,"given":"Ann L.","family":"Macrina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9374-5890","authenticated-orcid":false,"given":"Rupert M.","family":"Bruckmaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"issue":"2","key":"9506_CR1","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s10911-010-9180-2","volume":"15","author":"NJ Godde","year":"2010","unstructured":"Godde NJ, Galea RC, Elsum IA, Humbert PO. Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions. J Mammary Gland Biol Neoplasia. 2010;15(2):149\u201368. https:\/\/doi.org\/10.1007\/s10911-010-9180-2.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"4","key":"9506_CR2","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1152\/physrev.1980.60.4.1049","volume":"60","author":"YJ Topper","year":"1980","unstructured":"Topper YJ, Freeman CS. Multiple hormone interactions in the developmental biology of the mammary gland. Physiol Rev. 1980;60(4):1049\u2013106. https:\/\/doi.org\/10.1152\/physrev.1980.60.4.1049.","journal-title":"Physiol Rev."},{"issue":"6","key":"9506_CR3","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.3168\/jds.S0022-0302(96)76462-7","volume":"79","author":"IA Forsyth","year":"1996","unstructured":"Forsyth IA. The insulin-like growth factor and epidermal growth factor families in mammary cell growth in ruminants: action and interaction with hormones. J Dairy Sci. 1996;79(6):1085\u201396. https:\/\/doi.org\/10.3168\/jds.S0022-0302(96)76462-7.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR4","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.cvfa.2007.10.005","volume":"24","author":"S Godden","year":"2008","unstructured":"Godden S. Colostrum management for dairy calves. Vet Clin North Am Food Anim Pract. 2008;24(1):19\u201339. https:\/\/doi.org\/10.1016\/j.cvfa.2007.10.005.","journal-title":"Vet Clin North Am Food Anim Pract."},{"key":"9506_CR5","doi-asserted-by":"crossref","unstructured":"Butler JE. Immunoglobulins of the mammary secretions. In: eds BLLaVRS, editor. Lactation: A Comprehensive Treatise. New York: Academic Press; 1974. p. 217\u201355.","DOI":"10.1016\/B978-0-12-436703-6.50011-9"},{"key":"9506_CR6","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1016\/B978-012491543-5\/50107-8","volume-title":"Mucosal Immunology","author":"JE Butler","year":"2005","unstructured":"Butler JE, Kehrli ME. Immunoglobulins and Immunocytes in the Mammary Glandd and its Secretions. In: Bestechy JF, Beinenstock J, Lamm ME, Mayer L, McGhee JR, Strober W, editors. Mucosal Immunology. 3rd ed. Burlington, MA: Elsevier Academic Press; 2005. p. 1763\u201393.","edition":"3"},{"key":"9506_CR7","doi-asserted-by":"crossref","unstructured":"Jenness R. The composition of milk. In: VR LBS, editor. Lactation: a comprehensive treatise. New York: Academic Press; 1974. p. 3\u2013107.","DOI":"10.1016\/B978-0-12-436703-6.50007-7"},{"issue":"6","key":"9506_CR8","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1210\/edrv-14-6-710","volume":"14","author":"CE Grosvenor","year":"1993","unstructured":"Grosvenor CE, Picciano MF, Baumrucker CR. Hormones and growth factors in milk. Endocr Rev. 1993;14(6):710\u201328. https:\/\/doi.org\/10.1210\/edrv-14-6-710.","journal-title":"Endocr Rev."},{"key":"9506_CR9","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/B978-012384430-9\/50022-6","volume-title":"Handbook of Milk Composition","author":"WM Campana","year":"1995","unstructured":"Campana WM, Baumrucker CR. Hormones and growth factors in bovine milk. In: Jensen RG, editor. Handbook of Milk Composition. New York, NY: Academic Press; 1995. p. 476\u201394."},{"key":"9506_CR10","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/978-0-387-74087-4_16","volume":"606","author":"JW Blum","year":"2008","unstructured":"Blum JW, Baumrucker CR. Insulin-like growth factors (IGFs), IGF binding proteins, and other endocrine factors in milk: role in the newborn. Adv Exp Med Biol. 2008;606:397\u2013422. https:\/\/doi.org\/10.1007\/978-0-387-74087-4_16.","journal-title":"Adv Exp Med Biol."},{"issue":"4","key":"9506_CR11","doi-asserted-by":"publisher","first-page":"3683","DOI":"10.3168\/jds.2019-17357","volume":"103","author":"AJ Fischer-Tlustos","year":"2020","unstructured":"Fischer-Tlustos AJ, Hertogs K, van Niekerk JK, Nagorske M, Haines DM, Steele MA. Oligosaccharide concentrations in colostrum, transition milk, and mature milk of primi- and multiparous Holstein cows during the first week of lactation. J Dairy Sci. 2020;103(4):3683\u201395. https:\/\/doi.org\/10.3168\/jds.2019-17357.","journal-title":"J Dairy Sci."},{"key":"9506_CR12","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/978-3-319-69682-9_8","volume-title":"Proteomics in Domestic Animals: from Farm to Systems Biology","author":"LE Hern\u00e1ndez-Castellano","year":"2018","unstructured":"Hern\u00e1ndez-Castellano LE, Baumrucker CR, Gross J, Wellnitz O, Bruckmaier RM. Colostrum Proteomics Research: A Complex Fluid with Multiple Physiological Functions. In: de Almeida AM, Eckersall D, Miller I, editors. Proteomics in Domestic Animals: from Farm to Systems Biology. Cham: Springer International Publishing; 2018. p. 149\u201367."},{"issue":"13 Suppl","key":"9506_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2527\/jas.2008-1377","volume":"87","author":"K Stelwagen","year":"2009","unstructured":"Stelwagen K, Carpenter E, Haigh B, Hodgkinson A, Wheeler TT. Immune components of bovine colostrum and milk. J Anim Sci. 2009;87(13 Suppl):3\u20139. https:\/\/doi.org\/10.2527\/jas.2008-1377.","journal-title":"J Anim Sci."},{"issue":"7","key":"9506_CR14","doi-asserted-by":"publisher","first-page":"3031","DOI":"10.3168\/jds.2009-2963","volume":"93","author":"CR Baumrucker","year":"2010","unstructured":"Baumrucker CR, Burkett AM, Magliaro-Macrina AL, Dechow CD. Colostrogenesis: mass transfer of immunoglobulin G1 into colostrum. J Dairy Sci. 2010;93(7):3031\u20138. https:\/\/doi.org\/10.3168\/jds.2009-2963.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR15","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.cvfa.2007.11.001","volume":"24","author":"CC Chase","year":"2008","unstructured":"Chase CC, Hurley DJ, Reber AJ. Neonatal immune development in the calf and its impact on vaccine response. Vet Clin North Am Food Anim Pract. 2008;24(1):87\u2013104. https:\/\/doi.org\/10.1016\/j.cvfa.2007.11.001.","journal-title":"Vet Clin North Am Food Anim Pract."},{"key":"9506_CR16","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/jn\/84.1.43","volume":"84","author":"JG Lecce","year":"1964","unstructured":"Lecce JG, Morgan DO, Matrone G. Effect of Feeding Colostral and Milk Components on the Cessation of Intestinal Absorption of Large Molecules (Closure) in Neonatal Pigs. J Nutr. 1964;84:43\u20138. https:\/\/doi.org\/10.1093\/jn\/84.1.43.","journal-title":"J Nutr."},{"key":"9506_CR17","doi-asserted-by":"publisher","unstructured":"Raboisson D, Trillat P, Cahuzac C. Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact. PLoS One. 2016;11(3):e0150452. https:\/\/doi.org\/10.1371\/journal.pone.0150452.","DOI":"10.1371\/journal.pone.0150452"},{"issue":"6","key":"9506_CR18","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.3168\/jds.S0022-0302(04)73319-6","volume":"87","author":"HM Farrell Jr","year":"2004","unstructured":"Farrell HM Jr, Jimenez-Flores R, Bleck GT, Brown EM, Butler JE, Creamer LK, et al. Nomenclature of the proteins of cows\u2019 milk\u2013sixth revision. J Dairy Sci. 2004;87(6):1641\u201374. https:\/\/doi.org\/10.3168\/jds.S0022-0302(04)73319-6.","journal-title":"J Dairy Sci."},{"key":"9506_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ghir.2017.05.004","volume":"35","author":"Z Meyer","year":"2017","unstructured":"Meyer Z, Hoflich C, Wirthgen E, Olm S, Hammon HM, Hoeflich A. Analysis of the IGF-system in milk from farm animals - Occurrence, regulation, and biomarker potential. Growth Horm IGF Res. 2017;35:1\u20137. https:\/\/doi.org\/10.1016\/j.ghir.2017.05.004.","journal-title":"Growth Horm IGF Res."},{"issue":"10","key":"9506_CR20","doi-asserted-by":"publisher","first-page":"983","DOI":"10.2174\/1389203719666180608091849","volume":"19","author":"BH Sabha","year":"2018","unstructured":"Sabha BH, Alzahrani F, Almehdar HA, Uversky VN, Redwan EM. Disorder in Milk Proteins: Lactadherin Multifunctionality and Structure. Curr Protein Pept Sci. 2018;19(10):983\u201397. https:\/\/doi.org\/10.2174\/1389203719666180608091849.","journal-title":"Curr Protein Pept Sci."},{"issue":"5 Pt 2","key":"9506_CR21","doi-asserted-by":"publisher","first-page":"R1085","DOI":"10.1152\/ajpregu.1996.270.5.R1085","volume":"270","author":"DG Burrin","year":"1996","unstructured":"Burrin DG, Wester TJ, Davis TA, Amick S, Heath JP. Orally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs. Am J Physiol. 1996;270(5 Pt 2):R1085\u201391. https:\/\/doi.org\/10.1152\/ajpregu.1996.270.5.R1085.","journal-title":"Am J Physiol."},{"issue":"2","key":"9506_CR22","doi-asserted-by":"publisher","first-page":"685","DOI":"10.2527\/jas.2012-5758","volume":"91","author":"HM Hammon","year":"2013","unstructured":"Hammon HM, Steinhoff-Wagner J, Flor J, Schonhusen U, Metges CC. Lactation Biology Symposium: role of colostrum and colostrum components on glucose metabolism in neonatal calves. J Anim Sci. 2013;91(2):685\u201395. https:\/\/doi.org\/10.2527\/jas.2012-5758.","journal-title":"J Anim Sci."},{"issue":"2","key":"9506_CR23","doi-asserted-by":"publisher","first-page":"421","DOI":"10.2527\/1994.722421x","volume":"72","author":"TC Skaar","year":"1994","unstructured":"Skaar TC, Baumrucker CR, Deaver DR, Blum JW. Diet effects and ontogeny of alterations of circulating insulin-like growth factor binding proteins in newborn dairy calves. J Anim Sci. 1994;72(2):421\u20137. https:\/\/doi.org\/10.2527\/1994.722421x.","journal-title":"J Anim Sci."},{"issue":"5","key":"9506_CR24","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1159\/000244256","volume":"68","author":"PY Vacher","year":"1995","unstructured":"Vacher PY, Bestetti G, Blum JW. Insulin-like growth factor I absorption in the jejunum of neonatal calves. Biol Neonate. 1995;68(5):354\u201367. https:\/\/doi.org\/10.1159\/000244256.","journal-title":"Biol Neonate."},{"issue":"5","key":"9506_CR25","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.3168\/jds.S0022-0302(03)73765-5","volume":"86","author":"B Roffler","year":"2003","unstructured":"Roffler B, Fah A, Sauter SN, Hammon HM, Gallmann P, Brem G, et al. Intestinal morphology, epithelial cell proliferation, and absorptive capacity in neonatal calves fed milk-born insulin-like growth factor-I or a colostrum extract. J Dairy Sci. 2003;86(5):1797\u2013806. https:\/\/doi.org\/10.3168\/jds.S0022-0302(03)73765-5.","journal-title":"J Dairy Sci."},{"issue":"6","key":"9506_CR26","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.3168\/jds.S0022-0302(03)73791-6","volume":"86","author":"AL Sparks","year":"2003","unstructured":"Sparks AL, Kirkpatrick JG, Chamberlain CS, Waldner D, Spicer LJ. Insulin-like growth factor-I and its binding proteins in colostrum compared to measures in serum of Holstein neonates. J Dairy Sci. 2003;86(6):2022\u20139. https:\/\/doi.org\/10.3168\/jds.S0022-0302(03)73791-6.","journal-title":"J Dairy Sci."},{"issue":"2","key":"9506_CR27","doi-asserted-by":"publisher","first-page":"171","DOI":"10.3390\/ijms17020171","volume":"17","author":"N Iraci","year":"2016","unstructured":"Iraci N, Leonardi T, Gessler F, Vega B, Pluchino S. Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles. Int J Mol Sci. 2016;17(2):171. https:\/\/doi.org\/10.3390\/ijms17020171.","journal-title":"Int J Mol Sci."},{"key":"9506_CR28","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1146\/annurev.cellbio.12.1.575","volume":"12","author":"I Mellman","year":"1996","unstructured":"Mellman I. Endocytosis and molecular sorting. Annu Rev Cell Dev Biol. 1996;12:575\u2013625. https:\/\/doi.org\/10.1146\/annurev.cellbio.12.1.575.","journal-title":"Annu Rev Cell Dev Biol."},{"issue":"3","key":"9506_CR29","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s10571-016-0366-z","volume":"36","author":"ER Abels","year":"2016","unstructured":"Abels ER, Breakefield XO. Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake. Cell Mol Neurobiol. 2016;36(3):301\u201312. https:\/\/doi.org\/10.1007\/s10571-016-0366-z.","journal-title":"Cell Mol Neurobiol."},{"issue":"1","key":"9506_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3168\/jds.2019-16959","volume":"103","author":"I Van Hese","year":"2020","unstructured":"Van Hese I, Goossens K, Vandaele L, Opsomer G. Invited review: MicroRNAs in bovine colostrum-Focus on their origin and potential health benefits for the calf. J Dairy Sci. 2020;103(1):1\u201315. https:\/\/doi.org\/10.3168\/jds.2019-16959.","journal-title":"J Dairy Sci."},{"issue":"11","key":"9506_CR31","doi-asserted-by":"publisher","first-page":"2206","DOI":"10.3945\/jn.116.237651","volume":"146","author":"A Benmoussa","year":"2016","unstructured":"Benmoussa A, Lee CH, Laffont B, Savard P, Laugier J, Boilard E, et al. Commercial Dairy Cow Milk microRNAs Resist Digestion under Simulated Gastrointestinal Tract Conditions. J Nutr. 2016;146(11):2206\u201315. https:\/\/doi.org\/10.3945\/jn.116.237651.","journal-title":"J Nutr."},{"key":"9506_CR32","doi-asserted-by":"publisher","first-page":"611","DOI":"10.3389\/fimmu.2014.00611","volume":"5","author":"N Lawless","year":"2014","unstructured":"Lawless N, Vegh P, O\u2019Farrelly C, Lynn DJ. The Role of microRNAs in Bovine Infection and Immunity. Front Immunol. 2014;5:611. https:\/\/doi.org\/10.3389\/fimmu.2014.00611.","journal-title":"Front Immunol."},{"key":"9506_CR33","doi-asserted-by":"publisher","unstructured":"Gu Y, Li M, Wang T, Liang Y, Zhong Z, Wang X, et al. Lactation-related microRNA expression profiles of porcine breast milk exosomes. PLoS One. 2012;7(8):e43691. https:\/\/doi.org\/10.1371\/journal.pone.0043691.","DOI":"10.1371\/journal.pone.0043691"},{"key":"9506_CR34","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1146\/annurev-animal-020518-115300","volume":"7","author":"J Zempleni","year":"2019","unstructured":"Zempleni J, Sukreet S, Zhou F, Wu D, Mutai E. Milk-Derived Exosomes and Metabolic Regulation. Annu Rev Anim Biosci. 2019;7:245\u201362. https:\/\/doi.org\/10.1146\/annurev-animal-020518-115300.","journal-title":"Annu Rev Anim Biosci."},{"issue":"1","key":"9506_CR35","doi-asserted-by":"publisher","first-page":"1535750","DOI":"10.1080\/20013078.2018.1535750","volume":"7","author":"C Thery","year":"2018","unstructured":"Thery C. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7(1):1535750. https:\/\/doi.org\/10.1080\/20013078.2018.1535750.","journal-title":"J Extracell Vesicles."},{"issue":"1","key":"9506_CR36","first-page":"5","volume":"31","author":"CR Baumrucker","year":"1997","unstructured":"Baumrucker CR, Strbak VV. 5th International symposium on hormones and bioactive substances in milk: highlights. Endocr Regul. 1997;31(1):5\u20138.","journal-title":"Endocr Regul."},{"issue":"Suppl 2","key":"9506_CR37","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1439-0531.2008.01174.x","volume":"43","author":"FF Bartol","year":"2008","unstructured":"Bartol FF, Wiley AA, Bagnell CA. Epigenetic programming of porcine endometrial function and the lactocrine hypothesis. Reprod Domest Anim. 2008;43(Suppl 2):273\u20139. https:\/\/doi.org\/10.1111\/j.1439-0531.2008.01174.x.","journal-title":"Reprod Domest Anim."},{"issue":"12","key":"9506_CR38","doi-asserted-by":"publisher","first-page":"2978","DOI":"10.1017\/S1751731119001654","volume":"13","author":"CA Bagnell","year":"2019","unstructured":"Bagnell CA, Bartol FF. Review: Maternal programming of development in the pig and the lactocrine hypothesis. Animal. 2019;13(12):2978\u201385. https:\/\/doi.org\/10.1017\/S1751731119001654.","journal-title":"Animal."},{"issue":"8","key":"9506_CR39","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.3168\/jds.S0022-0302(90)78885-6","volume":"73","author":"GE Huston","year":"1990","unstructured":"Huston GE, Patton S. Factors related to the formation of cytoplasmic crescents on milk fat globules. J Dairy Sci. 1990;73(8):2061\u20136. https:\/\/doi.org\/10.3168\/jds.S0022-0302(90)78885-6.","journal-title":"J Dairy Sci."},{"issue":"3","key":"9506_CR40","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.cvfa.2018.07.005","volume":"34","author":"LM Sordillo","year":"2018","unstructured":"Sordillo LM. Mammary Gland Immunobiology and Resistance to Mastitis. Vet Clin North Am Food Anim Pract. 2018;34(3):507\u201323. https:\/\/doi.org\/10.1016\/j.cvfa.2018.07.005.","journal-title":"Vet Clin North Am Food Anim Pract."},{"issue":"3","key":"9506_CR41","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1152\/physrev.1959.39.3.534","volume":"39","author":"JL Linzell","year":"1959","unstructured":"Linzell JL. Physiology of the mammary glands. Physiol Rev. 1959;39(3):534\u201376. https:\/\/doi.org\/10.1152\/physrev.1959.39.3.534.","journal-title":"Physiol Rev."},{"issue":"1","key":"9506_CR42","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1113\/jphysiol.1974.sp010746","volume":"243","author":"JL Linzell","year":"1974","unstructured":"Linzell JL, Peaker M. Changes in colostrum composition and in the permeability of the mammary epithelium at about the time of parturition in the goat. J Physiol. 1974;243(1):129\u201351. https:\/\/doi.org\/10.1113\/jphysiol.1974.sp010746.","journal-title":"J Physiol."},{"key":"9506_CR43","first-page":"81","volume":"63","author":"CJ Wilde","year":"1998","unstructured":"Wilde CJ, Addey CV, Bryson JM, Finch LM, Knight CH, Peaker M. Autocrine regulation of milk secretion. Biochem Soc Symp. 1998;63:81\u201390.","journal-title":"Biochem Soc Symp."},{"issue":"1","key":"9506_CR44","doi-asserted-by":"publisher","first-page":"5378","DOI":"10.1038\/s41598-018-23770-z","volume":"8","author":"MM Ledet","year":"2018","unstructured":"Ledet MM, Vasquez AK, Rauner G, Bichoupan AA, Moroni P, Nydam DV, et al. The secretome from bovine mammosphere-derived cells (MDC) promotes angiogenesis, epithelial cell migration, and contains factors associated with defense and immunity. Sci Rep. 2018;8(1):5378. https:\/\/doi.org\/10.1038\/s41598-018-23770-z.","journal-title":"Sci Rep."},{"issue":"3","key":"9506_CR45","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1023\/a:1018707309361","volume":"3","author":"DA Nguyen","year":"1998","unstructured":"Nguyen DA, Neville MC. Tight junction regulation in the mammary gland. J Mammary Gland Biol Neoplasia. 1998;3(3):233\u201346. https:\/\/doi.org\/10.1023\/a:1018707309361.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"2","key":"9506_CR46","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s00424-011-1034-2","volume":"463","author":"AG Markov","year":"2012","unstructured":"Markov AG, Kruglova NM, Fomina YA, Fromm M, Amasheh S. Altered expression of tight junction proteins in mammary epithelium after discontinued suckling in mice. Pflugers Arch. 2012;463(2):391\u20138. https:\/\/doi.org\/10.1007\/s00424-011-1034-2.","journal-title":"Pflugers Arch."},{"issue":"3","key":"9506_CR47","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.bbamem.2007.10.018","volume":"1778","author":"G Krause","year":"2008","unstructured":"Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J, Blasig IE. Structure and function of claudins. Biochim Biophys Acta. 2008;1778(3):631\u201345. https:\/\/doi.org\/10.1016\/j.bbamem.2007.10.018.","journal-title":"Biochim Biophys Acta."},{"issue":"8","key":"9506_CR48","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1016\/j.bbamcr.2016.04.023","volume":"1863","author":"K Kobayashi","year":"2016","unstructured":"Kobayashi K, Tsugami Y, Matsunaga K, Oyama S, Kuki C, Kumura H. Prolactin and glucocorticoid signaling induces lactation-specific tight junctions concurrent with beta-casein expression in mammary epithelial cells. Biochim Biophys Acta. 2016;1863(8):2006\u201316. https:\/\/doi.org\/10.1016\/j.bbamcr.2016.04.023.","journal-title":"Biochim Biophys Acta."},{"key":"9506_CR49","doi-asserted-by":"publisher","unstructured":"Cowie AT, Forsyth IA, Hart IC. Hormonal control of lactation. Monogr Endocrinol. 1980;15:I-XIV, 1\u2013275. https:\/\/doi.org\/10.1007\/978-3-642-81389-4.","DOI":"10.1007\/978-3-642-81389-4"},{"issue":"4","key":"9506_CR50","doi-asserted-by":"publisher","first-page":"874","DOI":"10.3168\/jds.S0022-0302(00)74951-4","volume":"83","author":"HA Tucker","year":"2000","unstructured":"Tucker HA. Hormones, mammary growth, and lactation: a 41-year perspective. J Dairy Sci. 2000;83(4):874\u201384. https:\/\/doi.org\/10.3168\/jds.S0022-0302(00)74951-4.","journal-title":"J Dairy Sci."},{"key":"9506_CR51","doi-asserted-by":"crossref","unstructured":"Rook JA, Wheelock JV. Reviews on the progress of dairy science. Dairy Chemistry: The secretion of water and water soluble constituents in milk. J Dairy Res. 1967;34(3):273\u201387.","DOI":"10.1017\/S0022029900012449"},{"issue":"11","key":"9506_CR52","doi-asserted-by":"publisher","first-page":"9254","DOI":"10.3168\/jds.2016-11370","volume":"99","author":"CR Baumrucker","year":"2016","unstructured":"Baumrucker CR, Dechow CD, Macrina AL, Gross JJ, Bruckmaier RM. Mammary immunoglobulin transfer rates following prepartum milking. J Dairy Sci. 2016;99(11):9254\u201362. https:\/\/doi.org\/10.3168\/jds.2016-11370.","journal-title":"J Dairy Sci."},{"issue":"9","key":"9506_CR53","doi-asserted-by":"publisher","first-page":"4108","DOI":"10.3168\/jds.2007-0040","volume":"90","author":"SI Kehoe","year":"2007","unstructured":"Kehoe SI, Jayarao BM, Heinrichs AJ. A survey of bovine colostrum composition and colostrum management practices on Pennsylvania dairy farms. J Dairy Sci. 2007;90(9):4108\u201316. https:\/\/doi.org\/10.3168\/jds.2007-0040.","journal-title":"J Dairy Sci."},{"issue":"4","key":"9506_CR54","doi-asserted-by":"publisher","first-page":"2186","DOI":"10.3168\/jds.2013-7573","volume":"97","author":"EC Kessler","year":"2014","unstructured":"Kessler EC, Bruckmaier RM, Gross JJ. Milk production during the colostral period is not related to the later lactational performance in dairy cows. J Dairy Sci. 2014;97(4):2186\u201392. https:\/\/doi.org\/10.3168\/jds.2013-7573. Epub\u00a02014 Jan 31. PMID: 24485686.","journal-title":"J Dairy Sci."},{"issue":"3","key":"9506_CR55","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/BF02544331","volume":"25","author":"S Patton","year":"1990","unstructured":"Patton S, Canfield LM, Huston GE, Ferris AM, Jensen RG. Carotenoids of human colostrum. Lipids. 1990;25(3):159\u201365. https:\/\/doi.org\/10.1007\/BF02544331.","journal-title":"Lipids."},{"issue":"3","key":"9506_CR56","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.cvfa.2019.07.005","volume":"35","author":"SM Godden","year":"2019","unstructured":"Godden SM, Lombard JE, Woolums AR. Colostrum Management for Dairy Calves. Vet Clin North Am Food Anim Pract. 2019;35(3):535\u201356. https:\/\/doi.org\/10.1016\/j.cvfa.2019.07.005.","journal-title":"Vet Clin North Am Food Anim Pract."},{"issue":"5","key":"9506_CR57","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.3168\/jds.S0022-0302(91)78321-5","volume":"74","author":"JL Burton","year":"1991","unstructured":"Burton JL, McBride BW, Kennedy BW, Burton JH, Elsasser TH, Woodward B. Serum immunoglobulin profiles of dairy cows chronically treated with recombinant bovine somatotropin. J Dairy Sci. 1991;74(5):1589\u201398. https:\/\/doi.org\/10.3168\/jds.S0022-0302(91)78321-5. PMID: 1880268.","journal-title":"J Dairy Sci."},{"key":"9506_CR58","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.theriogenology.2018.09.002","volume":"125","author":"MP Smuts","year":"2019","unstructured":"Smuts MP, de Bruyn S, Thompson PN, Holm DE. Serum albumin concentration of donor cows as an indicator of developmental competence of oocytes. Theriogenology. 2019;125:184\u201392. https:\/\/doi.org\/10.1016\/j.theriogenology.2018.09.002.","journal-title":"Theriogenology."},{"issue":"2","key":"9506_CR59","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1017\/S0022029916000091","volume":"83","author":"J Samarutel","year":"2016","unstructured":"Samarutel J, Baumrucker CR, Gross JJ, Dechow CD, Bruckmaier RM. Quarter variation and correlations of colostrum albumin, immunoglobulin G1 and G2 in dairy cows. J Dairy Res. 2016;83(2):209\u201318. https:\/\/doi.org\/10.1017\/S0022029916000091.","journal-title":"J Dairy Res."},{"key":"9506_CR60","doi-asserted-by":"publisher","first-page":"520","DOI":"10.3389\/fimmu.2014.00520","volume":"5","author":"G Vidarsson","year":"2014","unstructured":"Vidarsson G, Dekkers G, Rispens T. IgG subclasses and allotypes: from structure to effector functions. Front Immunol. 2014;5:520. https:\/\/doi.org\/10.3389\/fimmu.2014.00520.","journal-title":"Front Immunol."},{"issue":"1","key":"9506_CR61","doi-asserted-by":"publisher","first-page":"7363","DOI":"10.1038\/s41598-019-40731-2","volume":"9","author":"NM Stapleton","year":"2019","unstructured":"Stapleton NM, Brinkhaus M, Armour KL, Bentlage AEH, de Taeye SW, Temming AR, et al. Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge. Sci Rep. 2019;9(1):7363. https:\/\/doi.org\/10.1038\/s41598-019-40731-2.","journal-title":"Sci Rep."},{"key":"9506_CR62","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/ncomms1608","volume":"2","author":"NM Stapleton","year":"2011","unstructured":"Stapleton NM, Andersen JT, Stemerding AM, Bjarnarson SP, Verheul RC, Gerritsen J, et al. Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nat Commun. 2011;2:599. https:\/\/doi.org\/10.1038\/ncomms1608.","journal-title":"Nat Commun."},{"issue":"4","key":"9506_CR63","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/s10911-011-9230-4","volume":"16","author":"SL Aitken","year":"2011","unstructured":"Aitken SL, Corl CM, Sordillo LM. Immunopathology of mastitis: insights into disease recognition and resolution. J Mammary Gland Biol Neoplasia. 2011;16(4):291\u2013304. https:\/\/doi.org\/10.1007\/s10911-011-9230-4.","journal-title":"J Mammary Gland Biol Neoplasia."},{"key":"9506_CR64","doi-asserted-by":"crossref","unstructured":"McGrath BA, Fox PF, McSweeney PLH, Kelly AL. Composition and properties of bovine colostrum: A review. Dairy Sci Technol. 2016:133\u201358.","DOI":"10.1007\/s13594-015-0258-x"},{"issue":"3\u20134","key":"9506_CR65","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/s0165-2427(00)00213-0","volume":"76","author":"K Hagiwara","year":"2000","unstructured":"Hagiwara K, Kataoka S, Yamanaka H, Kirisawa R, Iwai H. Detection of cytokines in bovine colostrum. Vet Immunol Immunopathol. 2000;76(3\u20134):183\u201390. https:\/\/doi.org\/10.1016\/s0165-2427(00)00213-0.","journal-title":"Vet Immunol Immunopathol."},{"key":"9506_CR66","unstructured":"Baumrucker CR, Macrina AL. Hormones and Regulatory Factors in Bovine Milk. Reference Module in Food Science. Elsiver; 2020. p. 1\u20137."},{"issue":"1","key":"9506_CR67","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1530\/acta.0.1210153","volume":"121","author":"H Ronge","year":"1989","unstructured":"Ronge H, Blum JW. Insulin-like growth factor I binding proteins in dairy cows, calves and bulls. Acta Endocrinol (Copenh). 1989;121(1):153\u201360. https:\/\/doi.org\/10.1530\/acta.0.1210153.","journal-title":"Acta Endocrinol (Copenh)."},{"issue":"2","key":"9506_CR68","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.3168\/jds.2017-14029","volume":"102","author":"M Zinicola","year":"2019","unstructured":"Zinicola M, Bicalho RC. Association of peripartum plasma insulin concentration with milk production, colostrum insulin levels, and plasma metabolites of Holstein cows. J Dairy Sci. 2019;102(2):1473\u201382. https:\/\/doi.org\/10.3168\/jds.2017-14029.","journal-title":"J Dairy Sci."},{"issue":"3","key":"9506_CR69","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1084\/jem.20021829","volume":"197","author":"C Chaudhury","year":"2003","unstructured":"Chaudhury C, Mehnaz S, Robinson JM, Hayton WL, Pearl DK, Roopenian DC, et al. The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan. J Exp Med. 2003;197(3):315\u201322. https:\/\/doi.org\/10.1084\/jem.20021829.","journal-title":"J Exp Med."},{"issue":"3","key":"9506_CR70","first-page":"251","volume":"20","author":"MD Perez","year":"1989","unstructured":"Perez MD, Sanchez L, Aranda P, Sala FJ, Calvo M. Time-course levels of alpha 2-macroglobulin and albumin in cow colostrum and milk and alpha 2-macroglobulin levels in mastitic cow milk. Ann Rech Vet. 1989;20(3):251\u20138.","journal-title":"Ann Rech Vet."},{"issue":"11","key":"9506_CR71","doi-asserted-by":"publisher","first-page":"7748","DOI":"10.3168\/jds.2015-9440","volume":"98","author":"SK Wall","year":"2015","unstructured":"Wall SK, Gross JJ, Kessler EC, Villez K, Bruckmaier RM. Blood-derived proteins in milk at start of lactation: Indicators of active or passive transfer. J Dairy Sci. 2015;98(11):7748\u201356. https:\/\/doi.org\/10.3168\/jds.2015-9440.","journal-title":"J Dairy Sci."},{"key":"9506_CR72","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/0-306-46832-8_31","volume":"480","author":"MJ Paape","year":"2000","unstructured":"Paape MJ, Shafer-Weaver K, Capuco AV, Van Oostveldt K, Burvenich C. Immune surveillance of mammary tissue by phagocytic cells. Adv Exp Med Biol. 2000;480:259\u201377. https:\/\/doi.org\/10.1007\/0-306-46832-8_31.","journal-title":"Adv Exp Med Biol."},{"issue":"Suppl 1","key":"9506_CR73","doi-asserted-by":"publisher","first-page":"S75","DOI":"10.1017\/s0007114500002282","volume":"84","author":"H Korhonen","year":"2000","unstructured":"Korhonen H, Marnila P, Gill HS. Milk immunoglobulins and complement factors. Br J Nutr. 2000;84(Suppl 1):S75-80. https:\/\/doi.org\/10.1017\/s0007114500002282.","journal-title":"Br J Nutr."},{"key":"9506_CR74","unstructured":"Musoke A, Rurangirwa F, Nantulya V. Biologicall properties of bovine immunoglobulins and systemic antibody responses. The Ruminant Immune System, Health, and Disease. Cambridge, UK: Cambridge University Press; 1986. p. 391\u2013408."},{"issue":"1\u20132","key":"9506_CR75","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/0165-2427(83)90056-9","volume":"4","author":"JE Butler","year":"1983","unstructured":"Butler JE. Bovine immunoglobulins: an augmented review. Vet Immunol Immunopathol. 1983;4(1\u20132):43\u2013152. https:\/\/doi.org\/10.1016\/0165-2427(83)90056-9.","journal-title":"Vet Immunol Immunopathol."},{"key":"9506_CR76","doi-asserted-by":"publisher","unstructured":"Turula H, Wobus CE. The Role of the Polymeric Immunoglobulin Receptor and Secretory Immunoglobulins during Mucosal Infection and Immunity. Viruses. 2018;10(5). https:\/\/doi.org\/10.3390\/v10050237.","DOI":"10.3390\/v10050237"},{"issue":"3","key":"9506_CR77","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1023\/a:1011383826719","volume":"6","author":"TW Keenan","year":"2001","unstructured":"Keenan TW. Milk lipid globules and their surrounding membrane: a brief history and perspectives for future research. J Mammary Gland Biol Neoplasia. 2001;6(3):365\u201371. https:\/\/doi.org\/10.1023\/a:1011383826719.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"6","key":"9506_CR78","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1016\/j.jprot.2009.11.008","volume":"73","author":"M Affolter","year":"2010","unstructured":"Affolter M, Grass L, Vanrobaeys F, Casado B, Kussmann M. Qualitative and quantitative profiling of the bovine milk fat globule membrane proteome. J Proteomics. 2010;73(6):1079\u201388. https:\/\/doi.org\/10.1016\/j.jprot.2009.11.008.","journal-title":"J Proteomics."},{"issue":"3","key":"9506_CR79","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/0165-2427(86)90076-0","volume":"13","author":"VL Frenyo","year":"1986","unstructured":"Frenyo VL, Butler JE, Guidry AJ. The association of extrinsic bovine IgG1, IgG2, SIgA and IgM with the major fractions and cells of milk. Vet Immunol Immunopathol. 1986;13(3):239\u201354. https:\/\/doi.org\/10.1016\/0165-2427(86)90076-0.","journal-title":"Vet Immunol Immunopathol."},{"key":"9506_CR80","doi-asserted-by":"publisher","unstructured":"Pringnitz DJ, Butler JE, Guidry AJ. In vivo proteolytic activity of the mammary gland. Contribution to the origin of secretory component, beta 2-microglobulin and bovine-associated mucoprotein (BAMP) in cows milk. Vet Immunol Immunopathol. 1985;9(2):143\u201360. https:\/\/doi.org\/10.1016\/0165-2427(85)90014-5.","DOI":"10.1016\/0165-2427(85)90014-5"},{"issue":"6","key":"9506_CR81","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/icb.1971.67","volume":"49","author":"MR Brandon","year":"1971","unstructured":"Brandon MR, Watson DL, Lascelles AK. The mechanism of transfer of immunoglobulin into mammary secretion of cows. Aust J Exp Biol Med Sci. 1971;49(6):613\u201323. https:\/\/doi.org\/10.1038\/icb.1971.67.","journal-title":"Aust J Exp Biol Med Sci."},{"issue":"4","key":"9506_CR82","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/icb.1972.41","volume":"50","author":"AJ Husband","year":"1972","unstructured":"Husband AJ, Brandon MR, Lascelles AK. Absorption and endogenous production of immunoglobulins in calves. Aust J Exp Biol Med Sci. 1972;50(4):491\u20138. https:\/\/doi.org\/10.1038\/icb.1972.41.","journal-title":"Aust J Exp Biol Med Sci."},{"issue":"4","key":"9506_CR83","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/0165-2427(80)90012-4","volume":"1","author":"J Guidry","year":"1980","unstructured":"Guidry J, Butler JE, Pearson RE, Weinland BT. IgA, igG1, IgG2, IgM, and BSA in serum and mammary secretion throughout lactation. Vet Immunol Immunopathol. 1980;1(4):329\u201341. https:\/\/doi.org\/10.1016\/0165-2427(80)90012-4.","journal-title":"Vet Immunol Immunopathol."},{"issue":"12","key":"9506_CR84","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.3168\/jds.S0022-0302(76)84486-4","volume":"59","author":"M Sasaki","year":"1976","unstructured":"Sasaki M, Davis CL, Larson BL. Production and turnover of IgG1 and IgG2 immunoglobulins in the bovine around parturition. J Dairy Sci. 1976;59(12):2046\u201355. https:\/\/doi.org\/10.3168\/jds.S0022-0302(76)84486-4.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR85","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/0304-4165(77)90149-0","volume":"497","author":"M Sasaki","year":"1977","unstructured":"Sasaki M, Larson BL, Nelson DR. Kinetic analysis of the binding of immunoglobulins IgG1 and IgG2 to bovine mammary cells. Biochim Biophys Acta. 1977;497(1):160\u201370. https:\/\/doi.org\/10.1016\/0304-4165(77)90149-0.","journal-title":"Biochim Biophys Acta."},{"key":"9506_CR86","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000385919","volume":"13","author":"TA Waldmann","year":"1969","unstructured":"Waldmann TA, Strober W. Metabolism of immunoglobulins. Prog. Allergy. 1969;13:1\u2013110. https:\/\/doi.org\/10.1159\/000385919.","journal-title":"Allergy."},{"issue":"39","key":"9506_CR87","doi-asserted-by":"publisher","first-page":"12639","DOI":"10.1021\/bi9913505","volume":"38","author":"WL Martin","year":"1999","unstructured":"Martin WL, Bjorkman PJ. Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution. Biochemistry. 1999;38(39):12639\u201347. https:\/\/doi.org\/10.1021\/bi9913505.","journal-title":"Biochemistry."},{"issue":"19","key":"9506_CR88","doi-asserted-by":"publisher","first-page":"3769","DOI":"10.1111\/j.1742-4658.2011.08299.x","volume":"278","author":"S Takimori","year":"2011","unstructured":"Takimori S, Shimaoka H, Furukawa J, Yamashita T, Amano M, Fujitani N, et al. Alteration of the N-glycome of bovine milk glycoproteins during early lactation. FEBS J. 2011;278(19):3769\u201381. https:\/\/doi.org\/10.1111\/j.1742-4658.2011.08299.x.","journal-title":"FEBS J."},{"issue":"32","key":"9506_CR89","doi-asserted-by":"publisher","first-page":"9698","DOI":"10.1021\/bi000749m","volume":"39","author":"AP West Jr","year":"2000","unstructured":"West AP Jr, Bjorkman PJ. Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,). Biochemistry. 2000;39(32):9698\u2013708. https:\/\/doi.org\/10.1021\/bi000749m.","journal-title":"Biochemistry."},{"issue":"6","key":"9506_CR90","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/icb.1971.69","volume":"49","author":"MR Brandon","year":"1971","unstructured":"Brandon MR, Lascelles AK. Relative efficiency of absorption of IgG 1, IgG 2, IgA and IgM in the newborn calf. Aust J Exp Biol Med Sci. 1971;49(6):629\u201333. https:\/\/doi.org\/10.1038\/icb.1971.69.","journal-title":"Aust J Exp Biol Med Sci."},{"key":"9506_CR91","unstructured":"Nielsen K, Sheppard J, Holmes W, Tizard I. Experimental bovine trypanosomiasis. Changes in serum immunoglobulins, complement and complement components in infected animals. Immunology. 1978;35(5):817\u201326."},{"key":"9506_CR92","unstructured":"Nansen P, Nielsen K. Metabolism of bovine immunoglobulin. I. Metabolism of bovine IgG in cattle with chronic pyogenic infections. Can J Comp Med Vet Sci. 1966;30(12):327\u201331."},{"issue":"6","key":"9506_CR93","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/j.immuni.2004.05.007","volume":"20","author":"M Yoshida","year":"2004","unstructured":"Yoshida M, Claypool SM, Wagner JS, Mizoguchi E, Mizoguchi A, Roopenian DC, et al. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity. 2004;20(6):769\u201383. https:\/\/doi.org\/10.1016\/j.immuni.2004.05.007.","journal-title":"Immunity."},{"issue":"2","key":"9506_CR94","doi-asserted-by":"publisher","first-page":"569","DOI":"10.3168\/jds.S0022-0302(05)72719-3","volume":"88","author":"A Shamay","year":"2005","unstructured":"Shamay A, Homans R, Fuerman Y, Levin I, Barash H, Silanikove N, et al. Expression of albumin in nonhepatic tissues and its synthesis by the bovine mammary gland. J Dairy Sci. 2005;88(2):569\u201376. https:\/\/doi.org\/10.3168\/jds.S0022-0302(05)72719-3.","journal-title":"J Dairy Sci."},{"issue":"14","key":"9506_CR95","doi-asserted-by":"publisher","first-page":"E2862","DOI":"10.1073\/pnas.1618291114","volume":"114","author":"M Pyzik","year":"2017","unstructured":"Pyzik M, Rath T, Kuo TT, Win S, Baker K, Hubbard JJ, et al. Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proc Natl Acad Sci U S A. 2017;114(14):E2862\u201371. https:\/\/doi.org\/10.1073\/pnas.1618291114.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"5","key":"9506_CR96","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1002\/hep.26338","volume":"58","author":"R Garcia-Martinez","year":"2013","unstructured":"Garcia-Martinez R, Caraceni P, Bernardi M, Gines P, Arroyo V, Jalan R. Albumin: pathophysiologic basis of its role in the treatment of cirrhosis and its complications. Hepatology. 2013;58(5):1836\u201346. https:\/\/doi.org\/10.1002\/hep.26338.","journal-title":"Hepatology."},{"issue":"6","key":"9506_CR97","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1248\/bpb.25.695","volume":"25","author":"U Kragh-Hansen","year":"2002","unstructured":"Kragh-Hansen U, Chuang VT, Otagiri M. Practical aspects of the ligand-binding and enzymatic properties of human serum albumin. Biol Pharm Bull. 2002;25(6):695\u2013704. https:\/\/doi.org\/10.1248\/bpb.25.695.","journal-title":"Biol Pharm Bull."},{"key":"9506_CR98","doi-asserted-by":"publisher","first-page":"229","DOI":"10.2147\/IJGM.S102819","volume":"9","author":"DG Levitt","year":"2016","unstructured":"Levitt DG, Levitt MD. Human serum albumin homeostasis: a new look at the roles of synthesis, catabolism, renal and gastrointestinal excretion, and the clinical value of serum albumin measurements. Int J Gen Med. 2016;9:229\u201355. https:\/\/doi.org\/10.2147\/IJGM.S102819.","journal-title":"Int J Gen Med."},{"issue":"5","key":"9506_CR99","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1016\/j.jhep.2013.08.001","volume":"59","author":"R Jalan","year":"2013","unstructured":"Jalan R, Bernardi M. Effective albumin concentration and cirrhosis mortality: from concept to reality. J Hepatol. 2013;59(5):918\u201320. https:\/\/doi.org\/10.1016\/j.jhep.2013.08.001.","journal-title":"J Hepatol."},{"key":"9506_CR100","doi-asserted-by":"publisher","unstructured":"Prinsen BH, de Sain-van der Velden MG. Albumin turnover: experimental approach and its application in health and renal diseases. Clin Chim Acta. 2004;347(1\u20132):1\u201314. https:\/\/doi.org\/10.1016\/j.cccn.2004.04.005.","DOI":"10.1016\/j.cccn.2004.04.005"},{"key":"9506_CR101","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jconrel.2015.06.006","volume":"211","author":"M Bern","year":"2015","unstructured":"Bern M, Sand KM, Nilsen J, Sandlie I, Andersen JT. The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery. J Control Release. 2015;211:144\u201362. https:\/\/doi.org\/10.1016\/j.jconrel.2015.06.006.","journal-title":"J Control Release."},{"issue":"13","key":"9506_CR102","doi-asserted-by":"publisher","first-page":"5084","DOI":"10.1073\/pnas.0600548103","volume":"103","author":"MA Wani","year":"2006","unstructured":"Wani MA, Haynes LD, Kim J, Bronson CL, Chaudhury C, Mohanty S, et al. Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene. Proc Natl Acad Sci U S A. 2006;103(13):5084\u20139. https:\/\/doi.org\/10.1073\/pnas.0600548103.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"2","key":"9506_CR103","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.jaci.2014.12.1937","volume":"136","author":"O Ardeniz","year":"2015","unstructured":"Ardeniz O, Unger S, Onay H, Ammann S, Keck C, Cianga C, et al. beta2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system. J Allergy Clin Immunol. 2015;136(2):392\u2013401. https:\/\/doi.org\/10.1016\/j.jaci.2014.12.1937.","journal-title":"J Allergy Clin Immunol."},{"issue":"4406","key":"9506_CR104","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1126\/science.451621","volume":"205","author":"S Nagase","year":"1979","unstructured":"Nagase S, Shimamune K, Shumiya S. Albumin-deficient rat mutant. Science. 1979;205(4406):590\u20131. https:\/\/doi.org\/10.1126\/science.451621.","journal-title":"Science."},{"issue":"1","key":"9506_CR105","first-page":"57","volume":"37","author":"U Kragh-Hansen","year":"1990","unstructured":"Kragh-Hansen U. Structure and ligand binding properties of human serum albumin. Dan Med Bull. 1990;37(1):57\u201384.","journal-title":"Dan Med Bull."},{"key":"9506_CR106","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.3389\/fimmu.2019.01540","volume":"10","author":"M Pyzik","year":"2019","unstructured":"Pyzik M, Sand KMK, Hubbard JJ, Andersen JT, Sandlie I, Blumberg RS. The Neonatal Fc Receptor (FcRn): A Misnomer? Front Immunol. 2019;10:1540. https:\/\/doi.org\/10.3389\/fimmu.2019.01540.","journal-title":"Front Immunol."},{"key":"9506_CR107","doi-asserted-by":"publisher","unstructured":"Lillie JH, Han SS. Secretory protein synthesis in the stimulated rat parotid gland. Temporal dissociation of the maximal response from secretion. J Cell Biol. 1973;59(3):708\u201321. https:\/\/doi.org\/10.1083\/jcb.59.3.708.","DOI":"10.1083\/jcb.59.3.708"},{"issue":"1","key":"9506_CR108","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1079\/PNS19690007","volume":"28","author":"FW Brambell","year":"1969","unstructured":"Brambell FW. The transmission of immune globulins from the mother to the foetal and newborn young. Proc Nutr Soc. 1969;28(1):35\u201341.","journal-title":"Proc Nutr Soc."},{"issue":"7473","key":"9506_CR109","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/s0140-6736(66)92190-8","volume":"2","author":"FW Brambell","year":"1966","unstructured":"Brambell FW. The transmission of immunity from mother to young and the catabolism of immunoglobulins. Lancet. 1966;2(7473):1087\u201393. https:\/\/doi.org\/10.1016\/s0140-6736(66)92190-8.","journal-title":"Lancet."},{"issue":"3","key":"9506_CR110","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1002\/eji.1830260327","volume":"26","author":"V Ghetie","year":"1996","unstructured":"Ghetie V, Hubbard JG, Kim JK, Tsen MF, Lee Y, Ward ES. Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur J Immunol. 1996;26(3):690\u20136. https:\/\/doi.org\/10.1002\/eji.1830260327.","journal-title":"Eur J Immunol."},{"issue":"4","key":"9506_CR111","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1046\/j.1365-2567.1996.d01-775.x","volume":"89","author":"EJ Israel","year":"1996","unstructured":"Israel EJ, Wilsker DF, Hayes KC, Schoenfeld D, Simister NE. Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn. Immunology. 1996;89(4):573\u20138. https:\/\/doi.org\/10.1046\/j.1365-2567.1996.d01-775.x.","journal-title":"Immunology."},{"issue":"11","key":"9506_CR112","doi-asserted-by":"publisher","first-page":"5512","DOI":"10.1073\/pnas.93.11.5512","volume":"93","author":"RP Junghans","year":"1996","unstructured":"Junghans RP, Anderson CL. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor. Proc Natl Acad Sci U S A. 1996;93(11):5512\u20136. https:\/\/doi.org\/10.1073\/pnas.93.11.5512.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"9","key":"9506_CR113","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1038\/nri2155","volume":"7","author":"DC Roopenian","year":"2007","unstructured":"Roopenian DC, Akilesh S. FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol. 2007;7(9):715\u201325. https:\/\/doi.org\/10.1038\/nri2155.","journal-title":"Nat Rev Immunol."},{"issue":"12","key":"9506_CR114","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1038\/nrm972","volume":"3","author":"R Rojas","year":"2002","unstructured":"Rojas R, Apodaca G. Immunoglobulin transport across polarized epithelial cells. Nat Rev Mol Cell Biol. 2002;3(12):944\u201355. https:\/\/doi.org\/10.1038\/nrm972.","journal-title":"Nat Rev Mol Cell Biol."},{"issue":"4","key":"9506_CR115","doi-asserted-by":"publisher","first-page":"448","DOI":"10.4103\/0366-6999.176084","volume":"129","author":"L Li","year":"2016","unstructured":"Li L, Dong M, Wang XG. The Implication and Significance of Beta 2 Microglobulin: A Conservative Multifunctional Regulator. Chin Med J (Engl). 2016;129(4):448\u201355. https:\/\/doi.org\/10.4103\/0366-6999.176084.","journal-title":"Chin Med J (Engl)."},{"issue":"4","key":"9506_CR116","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/j.1525-139X.2009.00584.x","volume":"22","author":"TB Drueke","year":"2009","unstructured":"Drueke TB, Massy ZA. Beta2-microglobulin. Semin Dial. 2009;22(4):378\u201380. https:\/\/doi.org\/10.1111\/j.1525-139X.2009.00584.x.","journal-title":"Semin Dial."},{"issue":"1\u20132","key":"9506_CR117","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/0165-2427(96)05559-6","volume":"53","author":"F Hoshi","year":"1996","unstructured":"Hoshi F, Nagai D, Higuchi S, Noso T, Takahashi A, Kawamura S. Purification of bovine beta 2-microglobulin from colostrum and its complete amino acid sequence. Vet Immunol Immunopathol. 1996;53(1\u20132):29\u201338. https:\/\/doi.org\/10.1016\/0165-2427(96)05559-6.","journal-title":"Vet Immunol Immunopathol."},{"issue":"Pt 11","key":"9506_CR118","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.1242\/jcs.115.11.2389","volume":"115","author":"A Praetor","year":"2002","unstructured":"Praetor A, Hunziker W. beta(2)-Microglobulin is important for cell surface expression and pH-dependent IgG binding of human FcRn. J Cell Sci. 2002;115(Pt 11):2389\u201397.","journal-title":"J Cell Sci."},{"issue":"31","key":"9506_CR119","doi-asserted-by":"publisher","first-page":"28038","DOI":"10.1074\/jbc.M202367200","volume":"277","author":"SM Claypool","year":"2002","unstructured":"Claypool SM, Dickinson BL, Yoshida M, Lencer WI, Blumberg RS. Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin. J Biol Chem. 2002;277(31):28038\u201350. https:\/\/doi.org\/10.1074\/jbc.M202367200.","journal-title":"J Biol Chem."},{"issue":"2","key":"9506_CR120","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1083\/jcb.71.2.666","volume":"71","author":"R Rodewald","year":"1976","unstructured":"Rodewald R. pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat. J Cell Biol. 1976;71(2):666\u20139. https:\/\/doi.org\/10.1083\/jcb.71.2.666.","journal-title":"J Cell Biol."},{"issue":"7","key":"9506_CR121","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1002\/eji.1830150718","volume":"15","author":"NE Simister","year":"1985","unstructured":"Simister NE, Rees AR. Isolation and characterization of an Fc receptor from neonatal rat small intestine. Eur J Immunol. 1985;15(7):733\u20138. https:\/\/doi.org\/10.1002\/eji.1830150718.","journal-title":"Eur J Immunol."},{"issue":"1 Pt 2","key":"9506_CR122","doi-asserted-by":"publisher","first-page":"159s","DOI":"10.1083\/jcb.99.1.159s","volume":"99","author":"R Rodewald","year":"1984","unstructured":"Rodewald R, Kraehenbuhl JP. Receptor-mediated transport of IgG. J Cell Biol. 1984;99(1 Pt 2):159s\u201364s. https:\/\/doi.org\/10.1083\/jcb.99.1.159s.","journal-title":"J Cell Biol."},{"issue":"6","key":"9506_CR123","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1084\/jem.180.6.2377","volume":"180","author":"CM Story","year":"1994","unstructured":"Story CM, Mikulska JE, Simister NE. A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. J Exp Med. 1994;180(6):2377\u201381. https:\/\/doi.org\/10.1084\/jem.180.6.2377.","journal-title":"J Exp Med."},{"issue":"Pt 3","key":"9506_CR124","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1042\/BJ20020200","volume":"367","author":"X Zhu","year":"2002","unstructured":"Zhu X, Peng J, Raychowdhury R, Nakajima A, Lencer WI, Blumberg RS. The heavy chain of neonatal Fc receptor for IgG is sequestered in endoplasmic reticulum by forming oligomers in the absence of beta2-microglobulin association. Biochem J. 2002;367(Pt 3):703\u201314. https:\/\/doi.org\/10.1042\/BJ20020200.","journal-title":"Biochem J."},{"issue":"4","key":"9506_CR125","doi-asserted-by":"publisher","first-page":"1746","DOI":"10.1091\/mbc.e03-11-0832","volume":"15","author":"SM Claypool","year":"2004","unstructured":"Claypool SM, Dickinson BL, Wagner JS, Johansen FE, Venu N, Borawski JA, et al. Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor. Mol Biol Cell. 2004;15(4):1746\u201359. https:\/\/doi.org\/10.1091\/mbc.e03-11-0832.","journal-title":"Mol Biol Cell."},{"issue":"2","key":"9506_CR126","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1203\/01.PDR.0000047663.81816.E3","volume":"53","author":"U Shah","year":"2003","unstructured":"Shah U, Dickinson BL, Blumberg RS, Simister NE, Lencer WI, Walker WA. Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatr Res. 2003;53(2):295\u2013301. https:\/\/doi.org\/10.1203\/01.PDR.0000047663.81816.E3.","journal-title":"Pediatr Res."},{"issue":"7","key":"9506_CR127","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1172\/JCI6968","volume":"104","author":"BL Dickinson","year":"1999","unstructured":"Dickinson BL, Badizadegan K, Wu Z, Ahouse JC, Zhu X, Simister NE, et al. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line. J Clin Invest. 1999;104(7):903\u201311. https:\/\/doi.org\/10.1172\/JCI6968.","journal-title":"J Clin Invest."},{"issue":"Pt 7","key":"9506_CR128","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1242\/jcs.113.7.1277","volume":"113","author":"KM McCarthy","year":"2000","unstructured":"McCarthy KM, Yoong Y, Simister NE. Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia. J Cell Sci. 2000;113(Pt 7):1277\u201385.","journal-title":"J Cell Sci."},{"issue":"Pt 11","key":"9506_CR129","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1242\/jcs.02367","volume":"118","author":"EE Newton","year":"2005","unstructured":"Newton EE, Wu Z, Simister NE. Characterization of basolateral-targeting signals in the neonatal Fc receptor. J Cell Sci. 2005;118(Pt 11):2461\u20139. https:\/\/doi.org\/10.1242\/jcs.02367.","journal-title":"J Cell Sci."},{"issue":"8","key":"9506_CR130","doi-asserted-by":"crossref","first-page":"3317","DOI":"10.4049\/jimmunol.157.8.3317","volume":"157","author":"JL Leach","year":"1996","unstructured":"Leach JL, Sedmak DD, Osborne JM, Rahill B, Lairmore MD, Anderson CL. Isolation from human placenta of the IgG transporter, FcRn, and localization to the syncytiotrophoblast: implications for maternal-fetal antibody transport. J Immunol. 1996;157(8):3317\u201322.","journal-title":"J Immunol."},{"issue":"2","key":"9506_CR131","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/s0198-8859(00)00244-5","volume":"62","author":"F Antohe","year":"2001","unstructured":"Antohe F, Radulescu L, Gafencu A, Ghetie V, Simionescu M. Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells. Hum Immunol. 2001;62(2):93\u2013105. https:\/\/doi.org\/10.1016\/s0198-8859(00)00244-5.","journal-title":"Hum Immunol."},{"issue":"30","key":"9506_CR132","doi-asserted-by":"publisher","first-page":"11076","DOI":"10.1073\/pnas.0402970101","volume":"101","author":"RJ Ober","year":"2004","unstructured":"Ober RJ, Martinez C, Lai X, Zhou J, Ward ES. Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level. Proc Natl Acad Sci U S A. 2004;101(30):11076\u201381. https:\/\/doi.org\/10.1073\/pnas.0402970101.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"4","key":"9506_CR133","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1093\/intimm\/dxh393","volume":"18","author":"I Kacskovics","year":"2006","unstructured":"Kacskovics I, Kis Z, Mayer B, West AP Jr, Tiangco NE, Tilahun M, et al. FcRn mediates elongated serum half-life of human IgG in cattle. Int Immunol. 2006;18(4):525\u201336. https:\/\/doi.org\/10.1093\/intimm\/dxh393.","journal-title":"Int Immunol."},{"issue":"2","key":"9506_CR134","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1007\/s11095-005-9226-0","volume":"23","author":"M Sakagami","year":"2006","unstructured":"Sakagami M, Omidi Y, Campbell L, Kandalaft LE, Morris CJ, Barar J, et al. Expression and transport functionality of FcRn within rat alveolar epithelium: a study in primary cell culture and in the isolated perfused lung. Pharm Res. 2006;23(2):270\u20139. https:\/\/doi.org\/10.1007\/s11095-005-9226-0.","journal-title":"Pharm Res."},{"issue":"12","key":"9506_CR135","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.humimm.2003.08.025","volume":"64","author":"P Cianga","year":"2003","unstructured":"Cianga P, Cianga C, Cozma L, Ward ES, Carasevici E. The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland. Hum Immunol. 2003;64(12):1152\u20139. https:\/\/doi.org\/10.1016\/j.humimm.2003.08.025.","journal-title":"Hum Immunol."},{"issue":"5","key":"9506_CR136","doi-asserted-by":"publisher","first-page":"3266","DOI":"10.4049\/jimmunol.166.5.3266","volume":"166","author":"X Zhu","year":"2001","unstructured":"Zhu X, Meng G, Dickinson BL, Li X, Mizoguchi E, Miao L, et al. MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells. J Immunol. 2001;166(5):3266\u201376. https:\/\/doi.org\/10.4049\/jimmunol.166.5.3266.","journal-title":"J Immunol."},{"issue":"3","key":"9506_CR137","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1073\/pnas.0711515105","volume":"105","author":"S Akilesh","year":"2008","unstructured":"Akilesh S, Huber TB, Wu H, Wang G, Hartleben B, Kopp JB, et al. Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci U S A. 2008;105(3):967\u201372. https:\/\/doi.org\/10.1073\/pnas.0711515105.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"2","key":"9506_CR138","doi-asserted-by":"publisher","first-page":"959","DOI":"10.4049\/jimmunol.1000353","volume":"186","author":"J Cervenak","year":"2011","unstructured":"Cervenak J, Bender B, Schneider Z, Magna M, Carstea BV, Liliom K, et al. Neonatal FcR overexpression boosts humoral immune response in transgenic mice. J Immunol. 2011;186(2):959\u201368. https:\/\/doi.org\/10.4049\/jimmunol.1000353.","journal-title":"J Immunol."},{"issue":"7","key":"9506_CR139","doi-asserted-by":"publisher","first-page":"3528","DOI":"10.4049\/jimmunol.170.7.3528","volume":"170","author":"DC Roopenian","year":"2003","unstructured":"Roopenian DC, Christianson GJ, Sproule TJ, Brown AC, Akilesh S, Jung N, et al. The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs. J Immunol. 2003;170(7):3528\u201333. https:\/\/doi.org\/10.4049\/jimmunol.170.7.3528.","journal-title":"J Immunol."},{"issue":"2","key":"9506_CR140","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1073\/pnas.89.2.638","volume":"89","author":"LN Gastinel","year":"1992","unstructured":"Gastinel LN, Simister NE, Bjorkman PJ. Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules. Proc Natl Acad Sci U S A. 1992;89(2):638\u201342. https:\/\/doi.org\/10.1073\/pnas.89.2.638.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"6504","key":"9506_CR141","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1038\/372379a0","volume":"372","author":"WP Burmeister","year":"1994","unstructured":"Burmeister WP, Huber AH, Bjorkman PJ. Crystal structure of the complex of rat neonatal Fc receptor with Fc. Nature. 1994;372(6504):379\u201383. https:\/\/doi.org\/10.1038\/372379a0.","journal-title":"Nature."},{"issue":"9","key":"9506_CR142","doi-asserted-by":"publisher","first-page":"6591","DOI":"10.1074\/jbc.M009483200","volume":"276","author":"RL Shields","year":"2001","unstructured":"Shields RL, Namenuk AK, Hong K, Meng YG, Rae J, Briggs J, et al. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem. 2001;276(9):6591\u2013604. https:\/\/doi.org\/10.1074\/jbc.M009483200.","journal-title":"J Biol Chem."},{"key":"9506_CR143","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1146\/annurev.immunol.18.1.739","volume":"18","author":"V Ghetie","year":"2000","unstructured":"Ghetie V, Ward ES. Multiple roles for the major histocompatibility complex class I- related receptor FcRn. Annu Rev Immunol. 2000;18:739\u201366. https:\/\/doi.org\/10.1146\/annurev.immunol.18.1.739.","journal-title":"Annu Rev Immunol."},{"issue":"6","key":"9506_CR144","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1007\/s10875-010-9468-4","volume":"30","author":"TT Kuo","year":"2010","unstructured":"Kuo TT, Baker K, Yoshida M, Qiao SW, Aveson VG, Lencer WI, et al. Neonatal Fc receptor: from immunity to therapeutics. J Clin Immunol. 2010;30(6):777\u201389. https:\/\/doi.org\/10.1007\/s10875-010-9468-4.","journal-title":"J Clin Immunol."},{"issue":"15","key":"9506_CR145","doi-asserted-by":"publisher","first-page":"4983","DOI":"10.1021\/bi052628y","volume":"45","author":"C Chaudhury","year":"2006","unstructured":"Chaudhury C, Brooks CL, Carter DC, Robinson JM, Anderson CL. Albumin binding to FcRn: distinct from the FcRn-IgG interaction. Biochemistry. 2006;45(15):4983\u201390. https:\/\/doi.org\/10.1021\/bi052628y.","journal-title":"Biochemistry."},{"issue":"11","key":"9506_CR146","doi-asserted-by":"publisher","first-page":"7812","DOI":"10.1074\/jbc.M113.537563","volume":"289","author":"V Oganesyan","year":"2014","unstructured":"Oganesyan V, Damschroder MM, Cook KE, Li Q, Gao C, Wu H, et al. Structural insights into neonatal Fc receptor-based recycling mechanisms. J Biol Chem. 2014;289(11):7812\u201324. https:\/\/doi.org\/10.1074\/jbc.M113.537563.","journal-title":"J Biol Chem."},{"issue":"4","key":"9506_CR147","first-page":"169","volume":"41","author":"WH Giesecke","year":"1974","unstructured":"Giesecke WH, van den Heever LW. The diagnosis of bovine mastitis with particular reference to subclinical mastitis: a critical review of relevant literature. Onderstepoort J Vet Res. 1974;41(4):169\u2013211.","journal-title":"Onderstepoort J Vet Res."},{"issue":"2","key":"9506_CR148","first-page":"51","volume":"41","author":"WH Giesecke","year":"1974","unstructured":"Giesecke WH, Viljoen MH. The diagnosis of subclinical mastitis in lactating cows: a comparison of cytological methods and a monovalent radial immunodiffusion test. Onderstepoort J Vet Res. 1974;41(2):51\u201374.","journal-title":"Onderstepoort J Vet Res."},{"issue":"5","key":"9506_CR149","doi-asserted-by":"publisher","first-page":"2999","DOI":"10.4049\/jimmunol.179.5.2999","volume":"179","author":"X Liu","year":"2007","unstructured":"Liu X, Ye L, Christianson GJ, Yang JQ, Roopenian DC, Zhu X. NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences. J Immunol. 2007;179(5):2999\u20133011. https:\/\/doi.org\/10.4049\/jimmunol.179.5.2999.","journal-title":"J Immunol."},{"issue":"6","key":"9506_CR150","doi-asserted-by":"publisher","first-page":"860","DOI":"10.4161\/mabs.26507","volume":"5","author":"J Cervenak","year":"2013","unstructured":"Cervenak J, Doleschall M, Bender B, Mayer B, Schneider Z, Doleschall Z, et al. NFkappaB induces overexpression of bovine FcRn: a novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn. MAbs. 2013;5(6):860\u201371. https:\/\/doi.org\/10.4161\/mabs.26507.","journal-title":"MAbs."},{"issue":"3","key":"9506_CR151","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1017\/S0022029915000345","volume":"82","author":"O Wellnitz","year":"2015","unstructured":"Wellnitz O, Zbinden C, Luttgenau J, Bollwein H, Bruckmaier RM. Different chronological patterns of appearance of blood derived milk components during mastitis indicate different mechanisms of transfer from blood into milk. J Dairy Res. 2015;82(3):322\u20137. https:\/\/doi.org\/10.1017\/S0022029915000345.","journal-title":"J Dairy Res."},{"issue":"3","key":"9506_CR152","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1017\/s0022029999003581","volume":"66","author":"D Levieux","year":"1999","unstructured":"Levieux D, Ollier A. Bovine immunoglobulin G, beta-lactoglobulin, alpha-lactalbumin and serum albumin in colostrum and milk during the early post partum period. J Dairy Res. 1999;66(3):421\u201330. https:\/\/doi.org\/10.1017\/s0022029999003581.","journal-title":"J Dairy Res."},{"issue":"3","key":"9506_CR153","doi-asserted-by":"publisher","first-page":"535","DOI":"10.3168\/jds.S0022-0302(83)81822-0","volume":"66","author":"B Poutrel","year":"1983","unstructured":"Poutrel B, Caffin JP, Rainard P. Physiological and pathological factors influencing bovine serum albumin content of milk. J Dairy Sci. 1983;66(3):535\u201341. https:\/\/doi.org\/10.3168\/jds.S0022-0302(83)81822-0.","journal-title":"J Dairy Sci."},{"issue":"10","key":"9506_CR154","first-page":"1181","volume":"79","author":"DD Bannerman","year":"1999","unstructured":"Bannerman DD, Goldblum SE. Direct effects of endotoxin on the endothelium: barrier function and injury. Lab Invest. 1999;79(10):1181\u201399.","journal-title":"Lab Invest."},{"issue":"3\u20134","key":"9506_CR155","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.vetimm.2005.04.012","volume":"107","author":"DD Bannerman","year":"2005","unstructured":"Bannerman DD, Chockalingam A, Paape MJ, Hope JC. The bovine innate immune response during experimentally-induced Pseudomonas aeruginosa mastitis. Vet Immunol Immunopathol. 2005;107(3\u20134):201\u201315. https:\/\/doi.org\/10.1016\/j.vetimm.2005.04.012.","journal-title":"Vet Immunol Immunopathol."},{"issue":"3","key":"9506_CR156","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1006\/jmbi.1993.1220","volume":"230","author":"AH Huber","year":"1993","unstructured":"Huber AH, Kelley RF, Gastinel LN, Bjorkman PJ. Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc. J Mol Biol. 1993;230(3):1077\u201383. https:\/\/doi.org\/10.1006\/jmbi.1993.1220.","journal-title":"J Mol Biol."},{"issue":"3","key":"9506_CR157","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1084\/jem.20020400","volume":"196","author":"GM Spiekermann","year":"2002","unstructured":"Spiekermann GM, Finn PW, Ward ES, Dumont J, Dickinson BL, Blumberg RS, et al. Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung. J Exp Med. 2002;196(3):303\u201310. https:\/\/doi.org\/10.1084\/jem.20020400.","journal-title":"J Exp Med."},{"issue":"2","key":"9506_CR158","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1006\/excr.2001.5330","volume":"269","author":"I Ellinger","year":"2001","unstructured":"Ellinger I, Rothe A, Grill M, Fuchs R. Apical to basolateral transcytosis and apical recycling of immunoglobulin G in trophoblast-derived BeWo cells: effects of low temperature, nocodazole, and cytochalasin D. Exp Cell Res. 2001;269(2):322\u201331. https:\/\/doi.org\/10.1006\/excr.2001.5330.","journal-title":"Exp Cell Res."},{"issue":"3","key":"9506_CR159","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1002\/(SICI)1521-4141(199903)29:03<733::AID-IMMU733>3.0.CO;2-C","volume":"29","author":"I Ellinger","year":"1999","unstructured":"Ellinger I, Schwab M, Stefanescu A, Hunziker W, Fuchs R. IgG transport across trophoblast-derived BeWo cells: a model system to study IgG transport in the placenta. Eur J Immunol. 1999;29(3):733\u201344. https:\/\/doi.org\/10.1002\/(SICI)1521-4141(199903)29:03%3c733::AID-IMMU733%3e3.0.CO;2-C.","journal-title":"Eur J Immunol."},{"issue":"45","key":"9506_CR160","doi-asserted-by":"publisher","first-page":"18406","DOI":"10.1073\/pnas.1115348108","volume":"108","author":"Y Bai","year":"2011","unstructured":"Bai Y, Ye L, Tesar DB, Song H, Zhao D, Bjorkman PJ, et al. Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport. Proc Natl Acad Sci U S A. 2011;108(45):18406\u201311. https:\/\/doi.org\/10.1073\/pnas.1115348108.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"11","key":"9506_CR161","doi-asserted-by":"publisher","first-page":"4388","DOI":"10.1073\/pnas.1012861108","volume":"108","author":"Z Li","year":"2011","unstructured":"Li Z, Palaniyandi S, Zeng R, Tuo W, Roopenian DC, Zhu X. Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection. Proc Natl Acad Sci U S A. 2011;108(11):4388\u201393. https:\/\/doi.org\/10.1073\/pnas.1012861108.","journal-title":"Proc Natl Acad Sci U S A."},{"key":"9506_CR162","unstructured":"Baumrucker CR, Hammon H. Presence of FcRn in the intestine of newborn calves. 2013."},{"issue":"7","key":"9506_CR163","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1128\/JVI.62.7.2234-2237.1988","volume":"62","author":"TE Besser","year":"1988","unstructured":"Besser TE, McGuire TC, Gay CC, Pritchett LC. Transfer of functional immunoglobulin G (IgG) antibody into the gastrointestinal tract accounts for IgG clearance in calves. J Virol. 1988;62(7):2234\u20137. https:\/\/doi.org\/10.1128\/JVI.62.7.2234-2237.1988.","journal-title":"J Virol."},{"issue":"6","key":"9506_CR164","doi-asserted-by":"publisher","first-page":"5694","DOI":"10.3168\/jds.2019-17408","volume":"103","author":"AJ Heinrichs","year":"2020","unstructured":"Heinrichs AJ, Jones CM, Erickson PS, Chester-Jones H, Anderson JL. Symposium review: Colostrum management and calf nutrition for profitable and sustainable dairy farms. J Dairy Sci. 2020;103(6):5694\u20139. https:\/\/doi.org\/10.3168\/jds.2019-17408.","journal-title":"J Dairy Sci."},{"issue":"8","key":"9506_CR165","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/nrm2728","volume":"10","author":"H Stenmark","year":"2009","unstructured":"Stenmark H. Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol. 2009;10(8):513\u201325. https:\/\/doi.org\/10.1038\/nrm2728.","journal-title":"Nat Rev Mol Cell Biol."},{"issue":"1","key":"9506_CR166","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/s41580-019-0177-4","volume":"21","author":"M Vietri","year":"2020","unstructured":"Vietri M, Radulovic M, Stenmark H. The many functions of ESCRTs. Nat Rev Mol Cell Biol. 2020;21(1):25\u201342. https:\/\/doi.org\/10.1038\/s41580-019-0177-4.","journal-title":"Nat Rev Mol Cell Biol."},{"issue":"1","key":"9506_CR167","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/nrm.2016.121","volume":"18","author":"J Schoneberg","year":"2017","unstructured":"Schoneberg J, Lee IH, Iwasa JH, Hurley JH. Reverse-topology membrane scission by the ESCRT proteins. Nat Rev Mol Cell Biol. 2017;18(1):5\u201317. https:\/\/doi.org\/10.1038\/nrm.2016.121.","journal-title":"Nat Rev Mol Cell Biol."},{"issue":"8","key":"9506_CR168","doi-asserted-by":"publisher","first-page":"7309","DOI":"10.1074\/jbc.M410752200","volume":"280","author":"NL Wernick","year":"2005","unstructured":"Wernick NL, Haucke V, Simister NE. Recognition of the tryptophan-based endocytosis signal in the neonatal Fc Receptor by the mu subunit of adaptor protein-2. J Biol Chem. 2005;280(8):7309\u201316. https:\/\/doi.org\/10.1074\/jbc.M410752200.","journal-title":"J Biol Chem."},{"issue":"7","key":"9506_CR169","doi-asserted-by":"publisher","first-page":"5240","DOI":"10.1074\/jbc.M006684200","volume":"276","author":"Z Wu","year":"2001","unstructured":"Wu Z, Simister NE. Tryptophan- and dileucine-based endocytosis signals in the neonatal Fc receptor. J Biol Chem. 2001;276(7):5240\u20137. https:\/\/doi.org\/10.1074\/jbc.M006684200.","journal-title":"J Biol Chem."},{"issue":"Pt 8","key":"9506_CR170","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1242\/jcs.114.8.1591","volume":"114","author":"KM McCarthy","year":"2001","unstructured":"McCarthy KM, Lam M, Subramanian L, Shakya R, Wu Z, Newton EE, et al. Effects of mutations in potential phosphorylation sites on transcytosis of FcRn. J Cell Sci. 2001;114(Pt 8):1591\u20138.","journal-title":"J Cell Sci."},{"issue":"1","key":"9506_CR171","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1091\/mbc.e07-07-0658","volume":"19","author":"BL Dickinson","year":"2008","unstructured":"Dickinson BL, Claypool SM, D\u2019Angelo JA, Aiken ML, Venu N, Yen EH, et al. Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway. Mol Biol Cell. 2008;19(1):414\u201323. https:\/\/doi.org\/10.1091\/mbc.e07-07-0658.","journal-title":"Mol Biol Cell."},{"issue":"Pt 6","key":"9506_CR172","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1242\/jcs.108.6.2347","volume":"108","author":"M Berryman","year":"1995","unstructured":"Berryman M, Rodewald R. Beta 2-microglobulin co-distributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat. J Cell Sci. 1995;108(Pt 6):2347\u201360.","journal-title":"J Cell Sci."},{"issue":"8","key":"9506_CR173","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182695","volume":"12","author":"L D'Hooghe","year":"2017","unstructured":"D\u2019Hooghe L, Chalmers AD, Heywood S, Whitley P. Cell surface dynamics and cellular distribution of endogenous FcRn. PLoS One. 2017;12(8): e0182695. https:\/\/doi.org\/10.1371\/journal.pone.0182695.","journal-title":"PLoS One."},{"key":"9506_CR174","doi-asserted-by":"publisher","unstructured":"Mayer B, Doleschall M, Bender B, Bartyik J, Bosze Z, Frenyo LV, et al. Expression of the neonatal Fc receptor (FcRn) in the bovine mammary gland. J Dairy Res. 2005;72 Spec No:107\u201312. https:\/\/doi.org\/10.1017\/s0022029905001135. PMID: 16180728.","DOI":"10.1017\/s0022029905001135"},{"issue":"5","key":"9506_CR175","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1016\/j.jprot.2011.11.017","volume":"75","author":"TA Reinhardt","year":"2012","unstructured":"Reinhardt TA, Lippolis JD, Nonnecke BJ, Sacco RE. Bovine milk exosome proteome. J Proteomics. 2012;75(5):1486\u201392. https:\/\/doi.org\/10.1016\/j.jprot.2011.11.017.","journal-title":"J Proteomics."},{"issue":"4","key":"9506_CR176","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1017\/S0022029906001889","volume":"73","author":"TA Reinhardt","year":"2006","unstructured":"Reinhardt TA, Lippolis JD. Bovine milk fat globule membrane proteome. J Dairy Res. 2006;73(4):406\u201316. https:\/\/doi.org\/10.1017\/S0022029906001889.","journal-title":"J Dairy Res."},{"issue":"6","key":"9506_CR177","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.3168\/jds.2007-0952","volume":"91","author":"TA Reinhardt","year":"2008","unstructured":"Reinhardt TA, Lippolis JD. Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk. J Dairy Sci. 2008;91(6):2307\u201318. https:\/\/doi.org\/10.3168\/jds.2007-0952.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR178","doi-asserted-by":"publisher","first-page":"5933","DOI":"10.1038\/s41598-017-06288-8","volume":"7","author":"M Samuel","year":"2017","unstructured":"Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, et al. Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Sci Rep. 2017;7(1):5933. https:\/\/doi.org\/10.1038\/s41598-017-06288-8.","journal-title":"Sci Rep."},{"issue":"8","key":"9506_CR179","doi-asserted-by":"publisher","first-page":"2788","DOI":"10.1073\/pnas.0810796106","volume":"106","author":"HP Montoyo","year":"2009","unstructured":"Montoyo HP, Vaccaro C, Hafner M, Ober RJ, Mueller W, Ward ES. Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice. Proc Natl Acad Sci U S A. 2009;106(8):2788\u201393. https:\/\/doi.org\/10.1073\/pnas.0810796106.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"3","key":"9506_CR180","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1046\/j.1365-2567.2002.01514.x","volume":"107","author":"B Mayer","year":"2002","unstructured":"Mayer B, Zolnai A, Frenyo LV, Jancsik V, Szentirmay Z, Hammarstrom L, et al. Redistribution of the sheep neonatal Fc receptor in the mammary gland around the time of parturition in ewes and its localization in the small intestine of neonatal lambs. Immunology. 2002;107(3):288\u201396. https:\/\/doi.org\/10.1046\/j.1365-2567.2002.01514.x.","journal-title":"Immunology."},{"issue":"4","key":"9506_CR181","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.acthis.2009.04.002","volume":"112","author":"A Sayed-Ahmed","year":"2010","unstructured":"Sayed-Ahmed A, Kassab M, Abd-Elmaksoud A, Elnasharty M, El-Kirdasy A. Expression and immunohistochemical localization of the neonatal Fc receptor (FcRn) in the mammary glands of the Egyptian water buffalo. Acta Histochem. 2010;112(4):383\u201391. https:\/\/doi.org\/10.1016\/j.acthis.2009.04.002.","journal-title":"Acta Histochem."},{"issue":"5","key":"9506_CR182","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0165-2427(82)90016-2","volume":"3","author":"HL Leary Jr","year":"1982","unstructured":"Leary HL Jr, Larson BL, Nelson DR. Immunohistochemical localization of IgG1 and IgG2 in prepartum and lactating bovine mammary tissue. Vet Immunol Immunopathol. 1982;3(5):509\u201314. https:\/\/doi.org\/10.1016\/0165-2427(82)90016-2.","journal-title":"Vet Immunol Immunopathol."},{"key":"9506_CR183","volume-title":"Lactation: a comprehensive treatise","author":"BL Larson","year":"1974","unstructured":"Larson BL, Smith VR. Lactation: a comprehensive treatise. New York: Academic Press; 1974."},{"key":"9506_CR184","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-1-4939-3804-9_1","volume":"1459","author":"C Viotti","year":"2016","unstructured":"Viotti C. ER to Golgi-Dependent Protein Secretion: The Conventional Pathway. Methods Mol Biol. 2016;1459:3\u201329. https:\/\/doi.org\/10.1007\/978-1-4939-3804-9_1.","journal-title":"Methods Mol Biol."},{"issue":"3","key":"9506_CR185","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1023\/a:1018711410270","volume":"3","author":"IH Mather","year":"1998","unstructured":"Mather IH, Keenan TW. Origin and secretion of milk lipids. J Mammary Gland Biol Neoplasia. 1998;3(3):259\u201373. https:\/\/doi.org\/10.1023\/a:1018711410270.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"2","key":"9506_CR186","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3168\/jds.S0022-0302(00)74870-3","volume":"83","author":"IH Mather","year":"2000","unstructured":"Mather IH. A review and proposed nomenclature for major proteins of the milk-fat globule membrane. J Dairy Sci. 2000;83(2):203\u201347. https:\/\/doi.org\/10.3168\/jds.S0022-0302(00)74870-3.","journal-title":"J Dairy Sci."},{"issue":"2\u20133","key":"9506_CR187","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/0304-4165(88)90050-5","volume":"965","author":"S Patton","year":"1988","unstructured":"Patton S, Huston GE. Incidence and characteristics of cell pieces on human milk fat globules. Biochim Biophys Acta. 1988;965(2\u20133):146\u201353. https:\/\/doi.org\/10.1016\/0304-4165(88)90050-5.","journal-title":"Biochim Biophys Acta."},{"issue":"4","key":"9506_CR188","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.4049\/jimmunol.172.4.2021","volume":"172","author":"RJ Ober","year":"2004","unstructured":"Ober RJ, Martinez C, Vaccaro C, Zhou J, Ward ES. Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor. FcRn J Immunol. 2004;172(4):2021\u20139. https:\/\/doi.org\/10.4049\/jimmunol.172.4.2021.","journal-title":"FcRn. J Immunol."},{"issue":"10","key":"9506_CR189","doi-asserted-by":"publisher","first-page":"5020","DOI":"10.1073\/pnas.75.10.5020","volume":"75","author":"M Sasaki","year":"1978","unstructured":"Sasaki M, Eigel WN, Keenan TW. Lactose and major milk proteins are present in secretory vesicle-rich fractions from lactating mammary gland. Proc Natl Acad Sci U S A. 1978;75(10):5020\u20134. https:\/\/doi.org\/10.1073\/pnas.75.10.5020.","journal-title":"Proc Natl Acad Sci U S A."},{"key":"9506_CR190","doi-asserted-by":"publisher","unstructured":"Ales E, Tabares L, Poyato JM, Valero V, Lindau M, Alvarez de Toledo G. High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism. Nat Cell Biol. 1999;1(1):40\u20134. https:\/\/doi.org\/10.1038\/9012.","DOI":"10.1038\/9012"},{"issue":"4","key":"9506_CR191","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/nn1205","volume":"7","author":"RG Staal","year":"2004","unstructured":"Staal RG, Mosharov EV, Sulzer D. Dopamine neurons release transmitter via a flickering fusion pore. Nat Neurosci. 2004;7(4):341\u20136. https:\/\/doi.org\/10.1038\/nn1205.","journal-title":"Nat Neurosci."},{"issue":"1","key":"9506_CR192","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.tcb.2004.11.004","volume":"15","author":"WI Lencer","year":"2005","unstructured":"Lencer WI, Blumberg RS. A passionate kiss, then run: exocytosis and recycling of IgG by FcRn. Trends Cell Biol. 2005;15(1):5\u20139. https:\/\/doi.org\/10.1016\/j.tcb.2004.11.004.","journal-title":"Trends Cell Biol."},{"issue":"4","key":"9506_CR193","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1172\/JCI106279","volume":"49","author":"A Morell","year":"1970","unstructured":"Morell A, Terry WD, Waldmann TA. Metabolic properties of IgG subclasses in man. J Clin Invest. 1970;49(4):673\u201380. https:\/\/doi.org\/10.1172\/JCI106279.","journal-title":"J Clin Invest."},{"issue":"3","key":"9506_CR194","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1111\/trf.12334","volume":"54","author":"H Einarsdottir","year":"2014","unstructured":"Einarsdottir H, Ji Y, Visser R, Mo C, Luo G, Scherjon S, et al. H435-containing immunoglobulin G3 allotypes are transported efficiently across the human placenta: implications for alloantibody-mediated diseases of the newborn. Transfusion. 2014;54(3):665\u201371. https:\/\/doi.org\/10.1111\/trf.12334.","journal-title":"Transfusion."},{"key":"9506_CR195","doi-asserted-by":"publisher","unstructured":"Einarsdottir HK, Stapleton NM, Scherjon S, Andersen JT, Rispens T, van der Schoot CE, et al. On the perplexingly low rate of transport of IgG2 across the human placenta. PLoS One. 2014;9(9):e108319. https:\/\/doi.org\/10.1371\/journal.pone.0108319.","DOI":"10.1371\/journal.pone.0108319"},{"key":"9506_CR196","doi-asserted-by":"publisher","unstructured":"Remec Pavlin M, Hurley JH. The ESCRTs - converging on mechanism. J Cell Sci. 2020;133(18). https:\/\/doi.org\/10.1242\/jcs.240333.","DOI":"10.1242\/jcs.240333"},{"key":"9506_CR197","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.3168\/jds.S0022-0302(78)83686-8","volume":"61","author":"JA Foley","year":"1978","unstructured":"Foley JA, Otterby DE. Availability, storage, treatment, composition, and feeding value of surplus colostrum: A review. J Dairy Sci. 1978;61:1033\u201360.","journal-title":"J Dairy Sci."},{"issue":"12","key":"9506_CR198","doi-asserted-by":"publisher","first-page":"2863","DOI":"10.3168\/jds.S0022-0302(84)81648-3","volume":"67","author":"BJ Nonnecke","year":"1984","unstructured":"Nonnecke BJ, Smith KL. Biochemical and antibacterial properties of bovine mammary secretion during mammary involution and at parturition. J Dairy Sci. 1984;67(12):2863\u201372. https:\/\/doi.org\/10.3168\/jds.S0022-0302(84)81648-3.","journal-title":"J Dairy Sci."},{"key":"9506_CR199","doi-asserted-by":"crossref","unstructured":"McCarthy OJ, Singh K. Physico-chemical properties of milk. In: McSweeney PLH, Fox PF, editors. Advanced Dairy Chemistry. New York: Springer; 2009.","DOI":"10.1007\/978-0-387-84865-5_15"},{"issue":"3","key":"9506_CR200","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1017\/s0022029904000263","volume":"71","author":"BD Madsen","year":"2004","unstructured":"Madsen BD, Rasmussen MD, Nielsen MO, Wiking L, Larsen LB. Physical properties of mammary secretions in relation to chemical changes during transition from colostrum to milk. J Dairy Res. 2004;71(3):263\u201372. https:\/\/doi.org\/10.1017\/s0022029904000263.","journal-title":"J Dairy Res."},{"issue":"11","key":"9506_CR201","doi-asserted-by":"publisher","first-page":"5012","DOI":"10.3168\/jds.2007-0192","volume":"90","author":"A Tsioulpas","year":"2007","unstructured":"Tsioulpas A, Grandison AS, Lewis MJ. Changes in physical properties of bovine milk from the colostrum period to early lactation. J Dairy Sci. 2007;90(11):5012\u20137. https:\/\/doi.org\/10.3168\/jds.2007-0192.","journal-title":"J Dairy Sci."},{"key":"9506_CR202","first-page":"161","volume":"22","author":"F Sebela","year":"1977","unstructured":"Sebela F, Klicnik V. The relationship between milk acidity after milking and cow\u2019s age. Zivocisna Vyroba (Animal Production). 1977;22:161\u201370.","journal-title":"Zivocisna Vyroba (Animal Production)."},{"key":"9506_CR203","first-page":"603","volume":"52","author":"JA Lucey","year":"1997","unstructured":"Lucey JA, Dick C, Singh H, Munro PA. Dissociation of colloidal calcium-phosphate depleted csein particle as influenced by pH and concentration of calcium and phosphate. Milchwissenschaft. 1997;52:603\u20136.","journal-title":"Milchwissenschaft."},{"issue":"4","key":"9506_CR204","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1085\/jgp.117.4.329","volume":"117","author":"M Grabe","year":"2001","unstructured":"Grabe M, Oster G. Regulation of organelle acidity. J Gen Physiol. 2001;117(4):329\u201344. https:\/\/doi.org\/10.1085\/jgp.117.4.329.","journal-title":"J Gen Physiol."},{"key":"9506_CR205","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/s0076-6879(00)27301-1","volume":"327","author":"MM Wu","year":"2000","unstructured":"Wu MM, Llopis J, Adams SR, McCaffery JM, Teter K, Kulomaa MS, et al. Studying organelle physiology with fusion protein-targeted avidin and fluorescent biotin conjugates. Methods Enzymol. 2000;327:546\u201364. https:\/\/doi.org\/10.1016\/s0076-6879(00)27301-1.","journal-title":"Methods Enzymol."},{"issue":"1","key":"9506_CR206","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s10911-013-9313-5","volume":"19","author":"CR Baumrucker","year":"2014","unstructured":"Baumrucker CR, Bruckmaier RM. Colostrogenesis: IgG1 transcytosis mechanisms. J Mammary Gland Biol Neoplasia. 2014;19(1):103\u201317. https:\/\/doi.org\/10.1007\/s10911-013-9313-5.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"12","key":"9506_CR207","doi-asserted-by":"publisher","first-page":"3812","DOI":"10.3168\/jds.S0022-0302(93)77725-5","volume":"76","author":"FL Schanbacher","year":"1993","unstructured":"Schanbacher FL, Goodman RE, Talhouk RS. Bovine mammary lactoferrin: implications from messenger ribonucleic acid (mRNA) sequence and regulation contrary to other milk proteins. J Dairy Sci. 1993;76(12):3812\u201331. https:\/\/doi.org\/10.3168\/jds.S0022-0302(93)77725-5.","journal-title":"J Dairy Sci."},{"issue":"9","key":"9506_CR208","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1515\/bchm3.1988.369.2.1005","volume":"369","author":"L Sanchez","year":"1988","unstructured":"Sanchez L, Aranda P, Perez MD, Calvo M. Concentration of lactoferrin and transferrin throughout lactation in cow\u2019s colostrum and milk. Biol Chem Hoppe Seyler. 1988;369(9):1005\u20138. https:\/\/doi.org\/10.1515\/bchm3.1988.369.2.1005.","journal-title":"Biol Chem Hoppe Seyler."},{"issue":"1","key":"9506_CR209","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1017\/s0022029900016290","volume":"45","author":"B Reiter","year":"1978","unstructured":"Reiter B. Review of the progress of dairy science: antimicrobial systems in milk. J Dairy Res. 1978;45(1):131\u201347. https:\/\/doi.org\/10.1017\/s0022029900016290.","journal-title":"J Dairy Res."},{"issue":"3","key":"9506_CR210","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1093\/jaoac\/89.3.898","volume":"89","author":"HE Indyk","year":"2006","unstructured":"Indyk HE, Filonzi EL, Gapper LW. Determination of minor proteins of bovine milk and colostrum by optical biosensor analysis. J AOAC Int. 2006;89(3):898\u2013902.","journal-title":"J AOAC Int."},{"key":"9506_CR211","doi-asserted-by":"publisher","unstructured":"Jameson GB, Anderson BF, Norris GE, Thomas DH, Baker EN. Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change. Acta Crystallogr D Biol Crystallogr. 1998;54(Pt 6 Pt 2):1319\u201335. https:\/\/doi.org\/10.1107\/s0907444998004417.","DOI":"10.1107\/s0907444998004417"},{"issue":"2","key":"9506_CR212","doi-asserted-by":"publisher","first-page":"139","DOI":"10.2174\/1389203719666180514150921","volume":"20","author":"L Hao","year":"2019","unstructured":"Hao L, Shan Q, Wei J, Ma F, Sun P. Lactoferrin: Major Physiological Functions and Applications. Curr Protein Pept Sci. 2019;20(2):139\u201344. https:\/\/doi.org\/10.2174\/1389203719666180514150921.","journal-title":"Curr Protein Pept Sci."},{"issue":"1","key":"9506_CR213","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1053\/rvsc.2000.0393","volume":"69","author":"TS Yang","year":"2000","unstructured":"Yang TS, Wu SC, Wang SR. Serum and milk lactoferrin concentration and the correlation with some blood components in lactating sows. Res Vet Sci. 2000;69(1):95\u20137. https:\/\/doi.org\/10.1053\/rvsc.2000.0393.","journal-title":"Res Vet Sci."},{"key":"9506_CR214","doi-asserted-by":"crossref","unstructured":"Gokce E, Atakisi O, Kirmizigul AH, Unver A Erdogan HM. Passive immunity in lambs: Serum lactoferrin concentrations as a predictor of IgG concentration and its relation to health status from birth to 12 weeks of life. Small Rumin Res. 2014;116(2\u20133):219\u201328.","DOI":"10.1016\/j.smallrumres.2013.11.006"},{"issue":"3","key":"9506_CR215","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/s0040-8166(02)00024-1","volume":"34","author":"AV Capuco","year":"2002","unstructured":"Capuco AV, Ellis S, Wood DL, Akers RM, Garrett W. Postnatal mammary ductal growth: three-dimensional imaging of cell proliferation, effects of estrogen treatment, and expression of steroid receptors in prepubertal calves. Tissue Cell. 2002;34(3):143\u201354. https:\/\/doi.org\/10.1016\/s0040-8166(02)00024-1.","journal-title":"Tissue Cell."},{"issue":"1","key":"9506_CR216","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s10911-005-2536-3","volume":"10","author":"AV Capuco","year":"2005","unstructured":"Capuco AV, Ellis S. Bovine mammary progenitor cells: current concepts and future directions. J Mammary Gland Biol Neoplasia. 2005;10(1):5\u201315. https:\/\/doi.org\/10.1007\/s10911-005-2536-3.","journal-title":"J Mammary Gland Biol Neoplasia."},{"key":"9506_CR217","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1002\/9780470720271.ch3","volume":"45","author":"D Schams","year":"1976","unstructured":"Schams D. Hormonal control of lactation. Ciba Found Symp. 1976;45:27\u201348. https:\/\/doi.org\/10.1002\/9780470720271.ch3.","journal-title":"Ciba Found Symp."},{"key":"9506_CR218","unstructured":"de Fremery P. On the influence of different hormones on lactation. J Physiol. 1936;87:50P\u20131P."},{"issue":"12","key":"9506_CR219","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.3168\/jds.S0022-0302(78)83794-1","volume":"61","author":"JR Harness","year":"1978","unstructured":"Harness JR, Anderson RR, Thompson LJ, Early DM, Younis AK. Induction of lactation by two techniques: success rate, milk composition, estrogen and progesterone in serum and milk, and ovarian effects. J Dairy Sci. 1978;61(12):1725\u201335. https:\/\/doi.org\/10.3168\/jds.S0022-0302(78)83794-1.","journal-title":"J Dairy Sci."},{"key":"9506_CR220","doi-asserted-by":"publisher","unstructured":"Hoffmann B, Goes de Pinho T, Schuler G. Determination of free and conjugated oestrogens in peripheral blood plasma, feces and urine of cattle throughout pregnancy. Exp Clin Endocrinol Diabetes. 1997;105(5):296\u2013303. https:\/\/doi.org\/10.1055\/s-0029-1211768.","DOI":"10.1055\/s-0029-1211768"},{"issue":"1","key":"9506_CR221","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3168\/jds.2007-0481","volume":"91","author":"DA Pape-Zambito","year":"2008","unstructured":"Pape-Zambito DA, Magliaro AL, Kensinger RS. 17Beta-estradiol and estrone concentrations in plasma and milk during bovine pregnancy. J Dairy Sci. 2008;91(1):127\u201335. https:\/\/doi.org\/10.3168\/jds.2007-0481.","journal-title":"J Dairy Sci."},{"issue":"5","key":"9506_CR222","doi-asserted-by":"publisher","first-page":"2923","DOI":"10.3168\/jds.2013-7795","volume":"97","author":"JJ Gross","year":"2014","unstructured":"Gross JJ, Kessler EC, Bjerre-Harpoth V, Dechow C, Baumrucker CR, Bruckmaier RM. Peripartal progesterone and prolactin have little effect on the rapid transport of immunoglobulin G into colostrum of dairy cows. J Dairy Sci. 2014;97(5):2923\u201331. https:\/\/doi.org\/10.3168\/jds.2013-7795.","journal-title":"J Dairy Sci."},{"issue":"8","key":"9506_CR223","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.3168\/jds.S0022-0302(77)84022-8","volume":"60","author":"RM Akers","year":"1977","unstructured":"Akers RM, Heald CW, Bibb TL, McGilliard ML. Effect of prepartum milk removal on quantitative morphology of bovine lactogenesis. J Dairy Sci. 1977;60(8):1273\u201382. https:\/\/doi.org\/10.3168\/jds.S0022-0302(77)84022-8.","journal-title":"J Dairy Sci."},{"issue":"3","key":"9506_CR224","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/s0022-5320(78)80055-0","volume":"63","author":"RM Akers","year":"1978","unstructured":"Akers RM, Heald CW. Stimulatory effect of prepartum milk removal on secretory cell differentiation in the bovine mammary gland. J Ultrastruct Res. 1978;63(3):316\u201322. https:\/\/doi.org\/10.1016\/s0022-5320(78)80055-0.","journal-title":"J Ultrastruct Res."},{"key":"9506_CR225","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2020.111084","volume":"520","author":"Y Ni","year":"2021","unstructured":"Ni Y, Chen Q, Cai J, Xiao L, Zhang J. Three lactation-related hormones: Regulation of hypothalamus-pituitary axis and function on lactation. Mol Cell Endocrinol. 2021;520: 111084. https:\/\/doi.org\/10.1016\/j.mce.2020.111084.","journal-title":"Mol Cell Endocrinol."},{"issue":"1","key":"9506_CR226","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1111\/1523-1747.ep12678099","volume":"63","author":"JC Porter","year":"1974","unstructured":"Porter JC. Proceedings: Hormonal regulation of breast development and activity. J Invest Dermatol. 1974;63(1):85\u201392. https:\/\/doi.org\/10.1111\/1523-1747.ep12678099.","journal-title":"J Invest Dermatol."},{"issue":"4","key":"9506_CR227","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1210\/endo-112-4-1324","volume":"112","author":"GT Goodman","year":"1983","unstructured":"Goodman GT, Akers RM, Friderici KH, Tucker HA. Hormonal regulation of alpha-lactalbumin secretion from bovine mammary tissue cultured in vitro. Endocrinology. 1983;112(4):1324\u201330. https:\/\/doi.org\/10.1210\/endo-112-4-1324.","journal-title":"Endocrinology."},{"issue":"2","key":"9506_CR228","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1111\/jpn.12205","volume":"99","author":"A Stark","year":"2015","unstructured":"Stark A, Wellnitz O, Dechow C, Bruckmaier R, Baumrucker C. Colostrogenesis during an induced lactation in dairy cattle. J Anim Physiol Anim Nutr (Berl). 2015;99(2):356\u201366. https:\/\/doi.org\/10.1111\/jpn.12205.","journal-title":"J Anim Physiol Anim Nutr (Berl)."},{"issue":"1","key":"9506_CR229","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/icb.1975.4","volume":"53","author":"MR Brandon","year":"1975","unstructured":"Brandon MR, Husband AJ, Lascelles AK. The effect of glucocorticoid on immunoglobulin secretion into colostrum in cows. Aust J Exp Biol Med Sci. 1975;53(1):43\u20138. https:\/\/doi.org\/10.1038\/icb.1975.4.","journal-title":"Aust J Exp Biol Med Sci."},{"issue":"3","key":"9506_CR230","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.3168\/jds.2013-7241","volume":"97","author":"AL Macrina","year":"2014","unstructured":"Macrina AL, Kauf AC, Pape-Zambito DA, Kensinger RS. Induced lactation in heifers: Effects of dexamethasone and age at induction on milk yield and composition. J Dairy Sci. 2014;97(3):1446\u201353. https:\/\/doi.org\/10.3168\/jds.2013-7241.","journal-title":"J Dairy Sci."},{"issue":"12","key":"9506_CR231","doi-asserted-by":"publisher","first-page":"3277","DOI":"10.3168\/jds.S0022-0302(02)74416-0","volume":"85","author":"LF Silva","year":"2002","unstructured":"Silva LF, VandeHaar MJ, Weber Nielsen MS, Smith GW. Evidence for a local effect of leptin in bovine mammary gland. J Dairy Sci. 2002;85(12):3277\u201386. https:\/\/doi.org\/10.3168\/jds.S0022-0302(02)74416-0.","journal-title":"J Dairy Sci."},{"issue":"4","key":"9506_CR232","first-page":"183","volume":"54","author":"D Yamaji","year":"2007","unstructured":"Yamaji D, Kamikawa A, Soliman MM, Ito T, Ahmed MM, Makondo K, et al. Leptin inhibits hepatocyte growth factor-induced ductal morphogenesis of bovine mammary epithelial cells. Jpn J Vet Res. 2007;54(4):183\u20139.","journal-title":"Jpn J Vet Res."},{"issue":"12","key":"9506_CR233","doi-asserted-by":"publisher","first-page":"5689","DOI":"10.2527\/jas2017.1777","volume":"95","author":"MF Palin","year":"2017","unstructured":"Palin MF, Farmer C, Duarte CRA. TRIENNIAL LACTATION SYMPOSIUM\/BOLFA: Adipokines affect mammary growth and function in farm animals. J Anim Sci. 2017;95(12):5689\u2013700. https:\/\/doi.org\/10.2527\/jas2017.1777.","journal-title":"J Anim Sci."},{"issue":"9","key":"9506_CR234","doi-asserted-by":"publisher","first-page":"2941","DOI":"10.3168\/jds.S0022-0302(04)73425-6","volume":"87","author":"Y Feuermann","year":"2004","unstructured":"Feuermann Y, Mabjeesh SJ, Shamay A. Leptin affects prolactin action on milk protein and fat synthesis in the bovine mammary gland. J Dairy Sci. 2004;87(9):2941\u20136. https:\/\/doi.org\/10.3168\/jds.S0022-0302(04)73425-6.","journal-title":"J Dairy Sci."},{"issue":"6","key":"9506_CR235","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.2527\/1995.7361861x","volume":"73","author":"RV Anthony","year":"1995","unstructured":"Anthony RV, Pratt SL, Liang R, Holland MD. Placental-fetal hormonal interactions: impact on fetal growth. J Anim Sci. 1995;73(6):1861\u201371. https:\/\/doi.org\/10.2527\/1995.7361861x.","journal-title":"J Anim Sci."},{"issue":"16","key":"9506_CR236","doi-asserted-by":"publisher","first-page":"5047","DOI":"10.1016\/S0021-9258(18)61967-2","volume":"246","author":"S Aloj","year":"1971","unstructured":"Aloj S, Edelhoch H. The molecular properties of human chorionic somatomammotropin. J Biol Chem. 1971;246(16):5047\u201352.","journal-title":"J Biol Chem."},{"issue":"2","key":"9506_CR237","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/s1642-431x(12)60006-0","volume":"8","author":"AV Alvarez-Oxiley","year":"2008","unstructured":"Alvarez-Oxiley AV, de Sousa NM, Beckers JF. Native and recombinant bovine placental lactogens. Reprod Biol. 2008;8(2):85\u2013106. https:\/\/doi.org\/10.1016\/s1642-431x(12)60006-0.","journal-title":"Reprod Biol."},{"issue":"3","key":"9506_CR238","doi-asserted-by":"publisher","first-page":"496","DOI":"10.3168\/jds.S0022-0302(97)75962-9","volume":"80","author":"JC Byatt","year":"1997","unstructured":"Byatt JC, Sorbet RH, Eppard PJ, Curran TL, Curran DF, Collier RJ. The effect of recombinant bovine placental lactogen on induced lactation in dairy heifers. J Dairy Sci. 1997;80(3):496\u2013503. https:\/\/doi.org\/10.3168\/jds.S0022-0302(97)75962-9.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR239","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1677\/joe.0.1400033","volume":"140","author":"JC Byatt","year":"1994","unstructured":"Byatt JC, Eppard PJ, Veenhuizen JJ, Curran TL, Curran DF, McGrath MF, et al. Stimulation of mammogenesis and lactogenesis by recombinant bovine placental lactogen in steroid-primed dairy heifers. J Endocrinol. 1994;140(1):33\u201343. https:\/\/doi.org\/10.1677\/joe.0.1400033.","journal-title":"J Endocrinol."},{"issue":"5","key":"9506_CR240","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.3168\/jds.S0022-0302(92)77870-9","volume":"75","author":"JC Byatt","year":"1992","unstructured":"Byatt JC, Eppard PJ, Munyakazi L, Sorbet RH, Veenhuizen JJ, Curran DF, et al. Stimulation of milk yield and feed intake by bovine placental lactogen in the dairy cow. J Dairy Sci. 1992;75(5):1216\u201323. https:\/\/doi.org\/10.3168\/jds.S0022-0302(92)77870-9.","journal-title":"J Dairy Sci."},{"issue":"9","key":"9506_CR241","doi-asserted-by":"publisher","first-page":"2911","DOI":"10.2527\/1992.7092911x","volume":"70","author":"JC Byatt","year":"1992","unstructured":"Byatt JC, Warren WC, Eppard PJ, Staten NR, Krivi GG, Collier RJ. Ruminant placental lactogens: structure and biology. J Anim Sci. 1992;70(9):2911\u201323. https:\/\/doi.org\/10.2527\/1992.7092911x.","journal-title":"J Anim Sci."},{"key":"9506_CR242","unstructured":"Hollmann KH. Cytology and Fine Structure of the Mammary Gland. In: Larson BLaS, V.R, editor. Lactation: A comprehensive Treatise. Academic Press, NY. p. 3\u201391."},{"issue":"3684","key":"9506_CR243","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1126\/science.149.3684.634","volume":"149","author":"CW Daniel","year":"1965","unstructured":"Daniel CW, Deome KB. Growth of Mouse Mammary Glands in Vivo after Monolayer Culture. Science. 1965;149(3684):634\u20136. https:\/\/doi.org\/10.1126\/science.149.3684.634.","journal-title":"Science."},{"issue":"Pt 1","key":"9506_CR244","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1242\/jcs.90.1.173","volume":"90","author":"GH Smith","year":"1988","unstructured":"Smith GH, Medina D. A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland. J Cell Sci. 1988;90(Pt 1):173\u201383.","journal-title":"J Cell Sci."},{"issue":"1","key":"9506_CR245","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1023\/a:1018752519356","volume":"4","author":"G Chepko","year":"1999","unstructured":"Chepko G, Smith GH. Mammary epithelial stem cells: our current understanding. J Mammary Gland Biol Neoplasia. 1999;4(1):35\u201352. https:\/\/doi.org\/10.1023\/a:1018752519356.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"1","key":"9506_CR246","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1186\/bcr1856","volume":"10","author":"GH Smith","year":"2008","unstructured":"Smith GH, Medina D. Re-evaluation of mammary stem cell biology based on in vivo transplantation. Breast Cancer Res. 2008;10(1):203. https:\/\/doi.org\/10.1186\/bcr1856.","journal-title":"Breast Cancer Res."},{"issue":"2","key":"9506_CR247","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s12015-007-0019-1","volume":"3","author":"C Brisken","year":"2007","unstructured":"Brisken C, Duss S. Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective. Stem Cell Rev. 2007;3(2):147\u201356. https:\/\/doi.org\/10.1007\/s12015-007-0019-1.","journal-title":"Stem Cell Rev."},{"issue":"14","key":"9506_CR248","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1093\/jnci\/djj267","volume":"98","author":"ML Asselin-Labat","year":"2006","unstructured":"Asselin-Labat ML, Shackleton M, Stingl J, Vaillant F, Forrest NC, Eaves CJ, et al. Steroid hormone receptor status of mouse mammary stem cells. J Natl Cancer Inst. 2006;98(14):1011\u20134. https:\/\/doi.org\/10.1093\/jnci\/djj267.","journal-title":"J Natl Cancer Inst."},{"issue":"1","key":"9506_CR249","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s10911-021-09483-6","volume":"26","author":"CA Dawson","year":"2021","unstructured":"Dawson CA, Visvader JE. The Cellular Organization of the Mammary Gland: Insights From Microscopy. J Mammary Gland Biol Neoplasia. 2021;26(1):71\u201385. https:\/\/doi.org\/10.1007\/s10911-021-09483-6.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"7","key":"9506_CR250","doi-asserted-by":"publisher","first-page":"2989","DOI":"10.1073\/pnas.0915148107","volume":"107","author":"M Beleut","year":"2010","unstructured":"Beleut M, Rajaram RD, Caikovski M, Ayyanan A, Germano D, Choi Y, et al. Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci U S A. 2010;107(7):2989\u201394. https:\/\/doi.org\/10.1073\/pnas.0915148107.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"17","key":"9506_CR251","doi-asserted-by":"publisher","first-page":"9744","DOI":"10.1073\/pnas.1732707100","volume":"100","author":"B Mulac-Jericevic","year":"2003","unstructured":"Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003;100(17):9744\u20139. https:\/\/doi.org\/10.1073\/pnas.1732707100.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1","key":"9506_CR252","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1023\/a:1015770423167","volume":"7","author":"MC Neville","year":"2002","unstructured":"Neville MC, McFadden TB, Forsyth I. Hormonal regulation of mammary differentiation and milk secretion. J Mammary Gland Biol Neoplasia. 2002;7(1):49\u201366. https:\/\/doi.org\/10.1023\/a:1015770423167.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"7299","key":"9506_CR253","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1038\/nature09027","volume":"465","author":"ML Asselin-Labat","year":"2010","unstructured":"Asselin-Labat ML, Vaillant F, Sheridan JM, Pal B, Wu D, Simpson ER, et al. Control of mammary stem cell function by steroid hormone signalling. Nature. 2010;465(7299):798\u2013802. https:\/\/doi.org\/10.1038\/nature09027.","journal-title":"Nature."},{"issue":"7299","key":"9506_CR254","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1038\/nature09091","volume":"465","author":"PA Joshi","year":"2010","unstructured":"Joshi PA, Jackson HW, Beristain AG, Di Grappa MA, Mote PA, Clarke CL, et al. Progesterone induces adult mammary stem cell expansion. Nature. 2010;465(7299):803\u20137. https:\/\/doi.org\/10.1038\/nature09091.","journal-title":"Nature."},{"issue":"7299","key":"9506_CR255","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1038\/465695a","volume":"465","author":"JP Lydon","year":"2010","unstructured":"Lydon JP. Stem cells: Cues from steroid hormones. Nature. 2010;465(7299):695\u20136. https:\/\/doi.org\/10.1038\/465695a.","journal-title":"Nature."},{"issue":"1","key":"9506_CR256","doi-asserted-by":"publisher","first-page":"16194","DOI":"10.1038\/s41598-018-34691-2","volume":"8","author":"L Finot","year":"2018","unstructured":"Finot L, Chanat E, Dessauge F. Molecular signature of the putative stem\/progenitor cells committed to the development of the bovine mammary gland at puberty. Sci Rep. 2018;8(1):16194. https:\/\/doi.org\/10.1038\/s41598-018-34691-2.","journal-title":"Sci Rep."},{"issue":"12","key":"9506_CR257","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1016\/0020-711x(87)90098-x","volume":"19","author":"LM Sordillo","year":"1987","unstructured":"Sordillo LM, Nickerson SC, Akers RM, Oliver SP. Secretion composition during bovine mammary involution and the relationship with mastitis. Int J Biochem. 1987;19(12):1165\u201372. https:\/\/doi.org\/10.1016\/0020-711x(87)90098-x.","journal-title":"Int J Biochem."},{"issue":"7","key":"9506_CR258","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.3168\/jds.S0022-0302(95)76787-X","volume":"78","author":"JW Hallberg","year":"1995","unstructured":"Hallberg JW, Dame KJ, Chester ST, Miller CC, Fox LK, Pankey JW, et al. The visual appearance and somatic cell count of mammary secretions collected from primigravid heifers during gestation and early postpartum. J Dairy Sci. 1995;78(7):1629\u201336. https:\/\/doi.org\/10.3168\/jds.S0022-0302(95)76787-X.","journal-title":"J Dairy Sci."},{"issue":"1","key":"9506_CR259","doi-asserted-by":"publisher","first-page":"100","DOI":"10.3168\/jds.S0022-0302(01)74457-8","volume":"84","author":"SM Andrew","year":"2001","unstructured":"Andrew SM. Effect of composition of colostrum and transition milk from Holstein heifers on specificity rates of antibiotic residue tests. J Dairy Sci. 2001;84(1):100\u20136. https:\/\/doi.org\/10.3168\/jds.S0022-0302(01)74457-8.","journal-title":"J Dairy Sci."},{"issue":"8","key":"9506_CR260","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1046\/j.1439-0450.2000.00388.x","volume":"47","author":"G Leitner","year":"2000","unstructured":"Leitner G, Shoshani E, Krifucks O, Chaffer M, Saran A. Milk leucocyte population patterns in bovine udder infection of different aetiology. J Vet Med B Infect Dis Vet Public Health. 2000;47(8):581\u20139. https:\/\/doi.org\/10.1046\/j.1439-0450.2000.00388.x.","journal-title":"J Vet Med B Infect Dis Vet Public Health."},{"issue":"3","key":"9506_CR261","first-page":"393","volume":"208","author":"JA Ellis","year":"1996","unstructured":"Ellis JA, Hassard LE, Cortese VS, Morley PS. Effects of perinatal vaccination on humoral and cellular immune responses in cows and young calves. J Am Vet Med Assoc. 1996;208(3):393\u2013400.","journal-title":"J Am Vet Med Assoc."},{"issue":"3\u20134","key":"9506_CR262","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1186\/BF03548647","volume":"29","author":"K Ostensson","year":"1988","unstructured":"Ostensson K, Hageltorn M, Astrom G. Differential cell counting in fraction-collected milk from dairy cows. Acta Vet Scand. 1988;29(3\u20134):493\u2013500.","journal-title":"Acta Vet Scand."},{"issue":"5","key":"9506_CR263","first-page":"257","volume":"38","author":"C Concha","year":"1986","unstructured":"Concha C. Cell types and their immunological functions in bovine mammary tissues and secretions\u2013a review of the literature. Nord Vet Med. 1986;38(5):257\u201372.","journal-title":"Nord Vet Med."},{"issue":"2","key":"9506_CR264","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0165-2427(87)90047-x","volume":"14","author":"GE Duhamel","year":"1987","unstructured":"Duhamel GE, Bernoco D, Davis WC, Osburn BI. Distribution of T and B lymphocytes in mammary dry secretions, colostrum and blood of adult dairy cattle. Vet Immunol Immunopathol. 1987;14(2):101\u201322. https:\/\/doi.org\/10.1016\/0165-2427(87)90047-x.","journal-title":"Vet Immunol Immunopathol."},{"issue":"12","key":"9506_CR265","doi-asserted-by":"publisher","first-page":"4320","DOI":"10.3168\/jds.S0022-0302(91)78627-X","volume":"74","author":"P Aranda","year":"1991","unstructured":"Aranda P, Sanchez L, Perez MD, Ena JM, Calvo M. Insulin in bovine colostrum and milk: evolution throughout lactation and binding to caseins. J Dairy Sci. 1991;74(12):4320\u20135. https:\/\/doi.org\/10.3168\/jds.S0022-0302(91)78627-X.","journal-title":"J Dairy Sci."},{"issue":"5","key":"9506_CR266","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1172\/JCI108565","volume":"58","author":"RS Bar","year":"1976","unstructured":"Bar RS, Gorden P, Roth J, Kahn CR, De Meyts P. Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting. J Clin Invest. 1976;58(5):1123\u201335. https:\/\/doi.org\/10.1172\/JCI108565.","journal-title":"J Clin Invest."},{"issue":"2","key":"9506_CR267","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1172\/JCI108646","volume":"59","author":"JH Helderman","year":"1977","unstructured":"Helderman JH, Strom TB. Emergence of insulin receptors upon alloimmune T cells in the rat. J Clin Invest. 1977;59(2):338\u201344. https:\/\/doi.org\/10.1172\/JCI108646.","journal-title":"J Clin Invest."},{"issue":"3","key":"9506_CR268","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1038\/ni.3659","volume":"18","author":"E Dror","year":"2017","unstructured":"Dror E, Dalmas E, Meier DT, Wueest S, Thevenet J, Thienel C, et al. Postprandial macrophage-derived IL-1beta stimulates insulin, and both synergistically promote glucose disposal and inflammation. Nat Immunol. 2017;18(3):283\u201392. https:\/\/doi.org\/10.1038\/ni.3659.","journal-title":"Nat Immunol."},{"key":"9506_CR269","doi-asserted-by":"publisher","unstructured":"Tsai S, Clemente-Casares X, Zhou AC, Lei H, Ahn JJ, Chan YT, et al. Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection. Cell Metab. 2018;28(6):922\u201334 e4. https:\/\/doi.org\/10.1016\/j.cmet.2018.08.003.","DOI":"10.1016\/j.cmet.2018.08.003"},{"issue":"2","key":"9506_CR270","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1002\/jso.2930020211","volume":"2","author":"JA Mohr","year":"1970","unstructured":"Mohr JA, Leu R, Mabry W. Colostral leukocytes. J Surg Oncol. 1970;2(2):163\u20137. https:\/\/doi.org\/10.1002\/jso.2930020211.","journal-title":"J Surg Oncol."},{"issue":"1","key":"9506_CR271","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/s0749-0720(15)30591-0","volume":"10","author":"TE Besser","year":"1994","unstructured":"Besser TE, Gay CC. The importance of colostrum to the health of the neonatal calf. Vet Clin North Am Food Anim Pract. 1994;10(1):107\u201317. https:\/\/doi.org\/10.1016\/s0749-0720(15)30591-0.","journal-title":"Vet Clin North Am Food Anim Pract."},{"issue":"5","key":"9506_CR272","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/s0007-1935(17)35781-0","volume":"130","author":"EF Logan","year":"1974","unstructured":"Logan EF. Colostral immunity to colibacillosis in the neonatal calf. Br Vet J. 1974;130(5):405\u201312. https:\/\/doi.org\/10.1016\/s0007-1935(17)35781-0.","journal-title":"Br Vet J."},{"issue":"3","key":"9506_CR273","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1093\/infdis\/163.3.470","volume":"163","author":"EB Belknap","year":"1991","unstructured":"Belknap EB, Baker JC, Patterson JS, Walker RD, Haines DM, Clark EG. The role of passive immunity in bovine respiratory syncytial virus-infected calves. J Infect Dis. 1991;163(3):470\u20136. https:\/\/doi.org\/10.1093\/infdis\/163.3.470.","journal-title":"J Infect Dis."},{"issue":"1\u20132","key":"9506_CR274","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/s0165-2427(01)00404-4","volume":"85","author":"EM Liebler-Tenorio","year":"2002","unstructured":"Liebler-Tenorio EM, Riedel-Caspari G, Pohlenz JF. Uptake of colostral leukocytes in the intestinal tract of newborn calves. Vet Immunol Immunopathol. 2002;85(1\u20132):33\u201340. https:\/\/doi.org\/10.1016\/s0165-2427(01)00404-4.","journal-title":"Vet Immunol Immunopathol."},{"issue":"7203","key":"9506_CR275","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1038\/nature07201","volume":"454","author":"R Medzhitov","year":"2008","unstructured":"Medzhitov R. Origin and physiological roles of inflammation. Nature. 2008;454(7203):428\u201335. https:\/\/doi.org\/10.1038\/nature07201.","journal-title":"Nature."},{"issue":"Suppl 1","key":"9506_CR276","doi-asserted-by":"publisher","first-page":"E76","DOI":"10.3168\/jds.2006-470","volume":"90","author":"FQ Zhao","year":"2007","unstructured":"Zhao FQ, Keating AF. Expression and regulation of glucose transporters in the bovine mammary gland. J Dairy Sci. 2007;90(Suppl 1):E76\u201386. https:\/\/doi.org\/10.3168\/jds.2006-470.","journal-title":"J Dairy Sci."},{"key":"9506_CR277","doi-asserted-by":"publisher","first-page":"9042851","DOI":"10.1155\/2017\/9042851","volume":"2017","author":"C Rosales","year":"2017","unstructured":"Rosales C, Uribe-Querol E. Phagocytosis: A Fundamental Process in Immunity. Biomed Res Int. 2017;2017:9042851. https:\/\/doi.org\/10.1155\/2017\/9042851.","journal-title":"Biomed Res Int."},{"issue":"1","key":"9506_CR278","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1111\/imr.12439","volume":"273","author":"R Levin","year":"2016","unstructured":"Levin R, Grinstein S, Canton J. The life cycle of phagosomes: formation, maturation, and resolution. Immunol Rev. 2016;273(1):156\u201379. https:\/\/doi.org\/10.1111\/imr.12439.","journal-title":"Immunol Rev."},{"issue":"10","key":"9506_CR279","doi-asserted-by":"publisher","first-page":"3573","DOI":"10.1182\/blood-2006-05-024539","volume":"108","author":"G Vidarsson","year":"2006","unstructured":"Vidarsson G, Stemerding AM, Stapleton NM, Spliethoff SE, Janssen H, Rebers FE, et al. FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis. Blood. 2006;108(10):3573\u20139. https:\/\/doi.org\/10.1182\/blood-2006-05-024539.","journal-title":"Blood."},{"issue":"2","key":"9506_CR280","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nri1266","volume":"4","author":"JM Woof","year":"2004","unstructured":"Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nat Rev Immunol. 2004;4(2):89\u201399. https:\/\/doi.org\/10.1038\/nri1266.","journal-title":"Nat Rev Immunol."},{"issue":"4","key":"9506_CR281","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036286","volume":"7","author":"A Vegh","year":"2012","unstructured":"Vegh A, Farkas A, Kovesdi D, Papp K, Cervenak J, Schneider Z, et al. FcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodies. PLoS One. 2012;7(4):e36286. https:\/\/doi.org\/10.1371\/journal.pone.0036286.","journal-title":"PLoS One."},{"issue":"1","key":"9506_CR282","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/j.1365-2796.2010.02237.x","volume":"268","author":"M Hager","year":"2010","unstructured":"Hager M, Cowland JB, Borregaard N. Neutrophil granules in health and disease. J Intern Med. 2010;268(1):25\u201334. https:\/\/doi.org\/10.1111\/j.1365-2796.2010.02237.x.","journal-title":"J Intern Med."},{"issue":"3","key":"9506_CR283","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/j.1365-3083.1990.tb02916.x","volume":"32","author":"OW Bjerrum","year":"1990","unstructured":"Bjerrum OW, Nissen MH, Borregaard N. Neutrophil beta-2 microglobulin: an inflammatory mediator. Scand J Immunol. 1990;32(3):233\u201342. https:\/\/doi.org\/10.1111\/j.1365-3083.1990.tb02916.x.","journal-title":"Scand J Immunol."},{"issue":"4","key":"9506_CR284","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1111\/j.1365-2567.2004.02121.x","volume":"114","author":"CM Stirling","year":"2005","unstructured":"Stirling CM, Charleston B, Takamatsu H, Claypool S, Lencer W, Blumberg RS, et al. Characterization of the porcine neonatal Fc receptor\u2013potential use for trans-epithelial protein delivery. Immunology. 2005;114(4):542\u201353. https:\/\/doi.org\/10.1111\/j.1365-2567.2004.02121.x.","journal-title":"Immunology."},{"key":"9506_CR285","doi-asserted-by":"publisher","first-page":"408","DOI":"10.3389\/fimmu.2014.00408","volume":"5","author":"K Baker","year":"2014","unstructured":"Baker K, Rath T, Pyzik M, Blumberg RS. The Role of FcRn in Antigen Presentation. Front Immunol. 2014;5:408. https:\/\/doi.org\/10.3389\/fimmu.2014.00408.","journal-title":"Front Immunol."},{"key":"9506_CR286","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1146\/annurev.immunol.22.012703.104538","volume":"23","author":"ES Trombetta","year":"2005","unstructured":"Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol. 2005;23:975\u20131028. https:\/\/doi.org\/10.1146\/annurev.immunol.22.012703.104538.","journal-title":"Annu Rev Immunol."},{"issue":"8","key":"9506_CR287","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/nri2368","volume":"8","author":"JM Vyas","year":"2008","unstructured":"Vyas JM, Van der Veen AG, Ploegh HL. The known unknowns of antigen processing and presentation. Nat Rev Immunol. 2008;8(8):607\u201318. https:\/\/doi.org\/10.1038\/nri2368.","journal-title":"Nat Rev Immunol."},{"issue":"5","key":"9506_CR288","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1084\/jem.143.5.1283","volume":"143","author":"MJ Bevan","year":"1976","unstructured":"Bevan MJ. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J Exp Med. 1976;143(5):1283\u20138. https:\/\/doi.org\/10.1084\/jem.143.5.1283.","journal-title":"J Exp Med."},{"issue":"6","key":"9506_CR289","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1016\/j.immuni.2013.11.003","volume":"39","author":"K Baker","year":"2013","unstructured":"Baker K, Rath T, Flak MB, Arthur JC, Chen Z, Glickman JN, et al. Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer. Immunity. 2013;39(6):1095\u2013107. https:\/\/doi.org\/10.1016\/j.immuni.2013.11.003.","journal-title":"Immunity."},{"issue":"8","key":"9506_CR290","doi-asserted-by":"publisher","first-page":"4674","DOI":"10.4049\/jimmunol.1003584","volume":"186","author":"X Liu","year":"2011","unstructured":"Liu X, Lu L, Yang Z, Palaniyandi S, Zeng R, Gao LY, et al. The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells. J Immunol. 2011;186(8):4674\u201386. https:\/\/doi.org\/10.4049\/jimmunol.1003584.","journal-title":"J Immunol."},{"issue":"27","key":"9506_CR291","doi-asserted-by":"publisher","first-page":"9337","DOI":"10.1073\/pnas.0801717105","volume":"105","author":"SW Qiao","year":"2008","unstructured":"Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, et al. Dependence of antibody-mediated presentation of antigen on FcRn. Proc Natl Acad Sci U S A. 2008;105(27):9337\u201342. https:\/\/doi.org\/10.1073\/pnas.0801717105.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"24","key":"9506_CR292","doi-asserted-by":"publisher","first-page":"9927","DOI":"10.1073\/pnas.1019037108","volume":"108","author":"K Baker","year":"2011","unstructured":"Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, et al. Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A. 2011;108(24):9927\u201332. https:\/\/doi.org\/10.1073\/pnas.1019037108.","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"2","key":"9506_CR293","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/s0165-2478(03)00078-6","volume":"88","author":"B Heyman","year":"2003","unstructured":"Heyman B. Feedback regulation by IgG antibodies. Immunol Lett. 2003;88(2):157\u201361. https:\/\/doi.org\/10.1016\/s0165-2478(03)00078-6.","journal-title":"Immunol Lett."},{"key":"9506_CR294","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1038\/2031352a0","volume":"203","author":"FW Brambell","year":"1964","unstructured":"Brambell FW, Hemmings WA, Morris IG. A Theoretical Model of Gamma-Globulin Catabolism. Nature. 1964;203:1352\u20134. https:\/\/doi.org\/10.1038\/2031352a0.","journal-title":"Nature."},{"key":"9506_CR295","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/s0065-3527(08)60086-x","volume":"42","author":"SP Tucker","year":"1993","unstructured":"Tucker SP, Compans RW. Virus infection of polarized epithelial cells. Adv Virus Res. 1993;42:187\u2013247. https:\/\/doi.org\/10.1016\/s0065-3527(08)60086-x.","journal-title":"Adv Virus Res."},{"issue":"5","key":"9506_CR296","doi-asserted-by":"publisher","first-page":"801","DOI":"10.3168\/jds.s0022-0302(82)82269-8","volume":"65","author":"SP Oliver","year":"1982","unstructured":"Oliver SP, Smith KL. Bovine mammary involution following intramammary infusion on colchicine and endotoxin at drying off. J Dairy Sci. 1982;65(5):801\u201313. https:\/\/doi.org\/10.3168\/jds.s0022-0302(82)82269-8.","journal-title":"J Dairy Sci."},{"issue":"8","key":"9506_CR297","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.3168\/jds.S0022-0302(76)84379-2","volume":"59","author":"S Patton","year":"1976","unstructured":"Patton S. Mechanisms of secretion: effects of colchicine and vincristine on composition and flow of milk in the goat. J Dairy Sci. 1976;59(8):1414\u20139. https:\/\/doi.org\/10.3168\/jds.S0022-0302(76)84379-2.","journal-title":"J Dairy Sci."},{"issue":"6","key":"9506_CR298","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.3168\/jds.S0022-0302(84)81440-X","volume":"67","author":"S Patton","year":"1984","unstructured":"Patton S, Welsch U, Singh S. Intramammary infusion technique for genetic engineering of the mammary gland. J Dairy Sci. 1984;67(6):1323\u20136. https:\/\/doi.org\/10.3168\/jds.S0022-0302(84)81440-X.","journal-title":"J Dairy Sci."},{"key":"9506_CR299","doi-asserted-by":"publisher","first-page":"117","DOI":"10.3389\/fendo.2018.00117","volume":"9","author":"JB Allard","year":"2018","unstructured":"Allard JB, Duan C. IGF-Binding Proteins: Why Do They Exist and Why Are There So Many? Front Endocrinol (Lausanne). 2018;9:117. https:\/\/doi.org\/10.3389\/fendo.2018.00117.","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"1","key":"9506_CR300","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3109\/08977199109000269","volume":"5","author":"P Nissley","year":"1991","unstructured":"Nissley P, Lopaczynski W. Insulin-like growth factor receptors. Growth Factors. 1991;5(1):29\u201343. https:\/\/doi.org\/10.3109\/08977199109000269.","journal-title":"Growth Factors."},{"issue":"2","key":"9506_CR301","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1210\/edrv-16-2-143","volume":"16","author":"D LeRoith","year":"1995","unstructured":"LeRoith D, Werner H, Beitner-Johnson D, Roberts CT Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev. 1995;16(2):143\u201363. https:\/\/doi.org\/10.1210\/edrv-16-2-143.","journal-title":"Endocr Rev."},{"issue":"1","key":"9506_CR302","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1210\/edrv-16-1-3","volume":"16","author":"JI Jones","year":"1995","unstructured":"Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev. 1995;16(1):3\u201334. https:\/\/doi.org\/10.1210\/edrv-16-1-3.","journal-title":"Endocr Rev."},{"key":"9506_CR303","doi-asserted-by":"publisher","first-page":"286","DOI":"10.3389\/fcell.2020.00286","volume":"8","author":"S Shrivastav","year":"2020","unstructured":"Shrivastav S, Bhardwaj A, Pathak KA, Shrivastav A. Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3): Unraveling the Role in Mediating IGF-Independent Effects Within the Cell. Front Cell Dev Biol. 2020;8:286. https:\/\/doi.org\/10.3389\/fcell.2020.00286.","journal-title":"Front Cell Dev Biol."},{"key":"9506_CR304","doi-asserted-by":"publisher","unstructured":"Cai Q, Dozmorov M, Oh Y. IGFBP-3\/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer. Cells. 2020;9(5).\u00a0https:\/\/doi.org\/10.3390\/cells9051261.","DOI":"10.3390\/cells9051261"},{"issue":"1","key":"9506_CR305","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/s12032-013-0805-3","volume":"31","author":"P Singh","year":"2014","unstructured":"Singh P, Alex JM, Bast F. Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer. Med Oncol. 2014;31(1):805. https:\/\/doi.org\/10.1007\/s12032-013-0805-3.","journal-title":"Med Oncol."},{"issue":"6","key":"9506_CR306","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1210\/edrv.22.6.0452","volume":"22","author":"J Nakae","year":"2001","unstructured":"Nakae J, Kido Y, Accili D. Distinct and overlapping functions of insulin and IGF-I receptors. Endocr Rev. 2001;22(6):818\u201335. https:\/\/doi.org\/10.1210\/edrv.22.6.0452.","journal-title":"Endocr Rev."},{"issue":"1","key":"9506_CR307","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0092-8674(05)80085-6","volume":"75","author":"J Baker","year":"1993","unstructured":"Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell. 1993;75(1):73\u201382.","journal-title":"Cell."},{"issue":"9","key":"9506_CR308","doi-asserted-by":"publisher","first-page":"5038","DOI":"10.1016\/S0021-9258(18)34631-3","volume":"257","author":"J Massague","year":"1982","unstructured":"Massague J, Czech MP. The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor. J Biol Chem. 1982;257(9):5038\u201345.","journal-title":"J Biol Chem."},{"issue":"2\u20133","key":"9506_CR309","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/s0304-4165(02)00317-3","volume":"1572","author":"N Dahms","year":"2002","unstructured":"Dahms N, Hancock MK. P-type lectins. Biochim Biophys Acta. 2002;1572(2\u20133):317\u201340. https:\/\/doi.org\/10.1016\/s0304-4165(02)00317-3.","journal-title":"Biochim Biophys Acta."},{"issue":"6137","key":"9506_CR310","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1038\/329301a0","volume":"329","author":"DO Morgan","year":"1987","unstructured":"Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, et al. Insulin-like growth factor II receptor as a multifunctional binding protein. Nature. 1987;329(6137):301\u20137. https:\/\/doi.org\/10.1038\/329301a0.","journal-title":"Nature."},{"issue":"4844","key":"9506_CR311","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1126\/science.2964083","volume":"239","author":"RG MacDonald","year":"1988","unstructured":"MacDonald RG, Pfeffer SR, Coussens L, Tepper MA, Brocklebank CM, Mole JE, et al. A single receptor binds both insulin-like growth factor II and mannose-6-phosphate. Science. 1988;239(4844):1134\u20137. https:\/\/doi.org\/10.1126\/science.2964083.","journal-title":"Science."},{"key":"9506_CR312","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/S0083-6729(08)00625-0","volume":"80","author":"J Brown","year":"2009","unstructured":"Brown J, Jones EY, Forbes BE. Interactions of IGF-II with the IGF2R\/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes. Vitam Horm. 2009;80:699\u2013719. https:\/\/doi.org\/10.1016\/S0083-6729(08)00625-0.","journal-title":"Vitam Horm."},{"issue":"12","key":"9506_CR313","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.tibs.2009.07.003","volume":"34","author":"J Brown","year":"2009","unstructured":"Brown J, Jones EY, Forbes BE. Keeping IGF-II under control: lessons from the IGF-II-IGF2R crystal structure. Trends Biochem Sci. 2009;34(12):612\u20139. https:\/\/doi.org\/10.1016\/j.tibs.2009.07.003.","journal-title":"Trends Biochem Sci."},{"issue":"3","key":"9506_CR314","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1038\/nrm1050","volume":"4","author":"P Ghosh","year":"2003","unstructured":"Ghosh P, Dahms NM, Kornfeld S. Mannose 6-phosphate receptors: new twists in the tale. Nat Rev Mol Cell Biol. 2003;4(3):202\u201312. https:\/\/doi.org\/10.1038\/nrm1050.","journal-title":"Nat Rev Mol Cell Biol."},{"issue":"34","key":"9506_CR315","doi-asserted-by":"publisher","first-page":"12658","DOI":"10.1073\/pnas.0405042101","volume":"101","author":"A Urayama","year":"2004","unstructured":"Urayama A, Grubb JH, Sly WS, Banks WA. Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier. Proc Natl Acad Sci U S A. 2004;101(34):12658\u201363. https:\/\/doi.org\/10.1073\/pnas.0405042101.","journal-title":"Proc Natl Acad Sci U S A."},{"key":"9506_CR316","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1146\/annurev-biochem-060815-014659","volume":"85","author":"JJ Bergeron","year":"2016","unstructured":"Bergeron JJ, Di Guglielmo GM, Dahan S, Dominguez M, Posner BI. Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction. Annu Rev Biochem. 2016;85:573\u201397. https:\/\/doi.org\/10.1146\/annurev-biochem-060815-014659.","journal-title":"Annu Rev Biochem."},{"issue":"3","key":"9506_CR317","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1016\/s0006-291x(84)80252-1","volume":"123","author":"DG Kay","year":"1984","unstructured":"Kay DG, Khan MN, Posner BI, Bergeron JJ. In vivo uptake of insulin into hepatic Golgi fractions: application of the diaminobenzidine-shift protocol. Biochem Biophys Res Commun. 1984;123(3):1144\u20138. https:\/\/doi.org\/10.1016\/s0006-291x(84)80252-1.","journal-title":"Biochem Biophys Res Commun."},{"issue":"10\u201311","key":"9506_CR318","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/s0300-9084(85)80112-7","volume":"67","author":"JL Carpentier","year":"1985","unstructured":"Carpentier JL, Fehlmann M, Van Obberghen E, Gorden P, Orci L. Insulin receptor internalization and recycling: mechanism and significance. Biochimie. 1985;67(10\u201311):1143\u20135. https:\/\/doi.org\/10.1016\/s0300-9084(85)80112-7.","journal-title":"Biochimie."},{"issue":"1\u20132","key":"9506_CR319","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1023\/A:1006883311233","volume":"182","author":"GM Di Guglielmo","year":"1998","unstructured":"Di Guglielmo GM, Drake PG, Baass PC, Authier F, Posner BI, Bergeron JJ. Insulin receptor internalization and signalling. Mol Cell Biochem. 1998;182(1\u20132):59\u201363.","journal-title":"Mol Cell Biochem."},{"issue":"1","key":"9506_CR320","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1083\/jcb.110.1.35","volume":"110","author":"JJ Doherty 2nd","year":"1990","unstructured":"Doherty JJ 2nd, Kay DG, Lai WH, Posner BI, Bergeron JJ. Selective degradation of insulin within rat liver endosomes. J Cell Biol. 1990;110(1):35\u201342. https:\/\/doi.org\/10.1083\/jcb.110.1.35.","journal-title":"J Cell Biol."},{"issue":"1","key":"9506_CR321","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.jcjd.2016.07.002","volume":"41","author":"BI Posner","year":"2017","unstructured":"Posner BI. Insulin Signalling: The Inside Story. Can J Diabetes. 2017;41(1):108\u201313. https:\/\/doi.org\/10.1016\/j.jcjd.2016.07.002.","journal-title":"Can J Diabetes."},{"issue":"5333","key":"9506_CR322","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1038\/235107a0","volume":"235","author":"WH Daughaday","year":"1972","unstructured":"Daughaday WH, Hall K, Raben MS, Salmon WD Jr, van den Brande JL, van Wyk JJ. Somatomedin: proposed designation for sulphation factor. Nature. 1972;235(5333):107. https:\/\/doi.org\/10.1038\/235107a0.","journal-title":"Nature."},{"issue":"2","key":"9506_CR323","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/0012-1606(80)90166-9","volume":"75","author":"AJ D'Ercole","year":"1980","unstructured":"D\u2019Ercole AJ, Applewhite GT, Underwood LE. Evidence that somatomedin is synthesized by multiple tissues in the fetus. Dev Biol. 1980;75(2):315\u201328. https:\/\/doi.org\/10.1016\/0012-1606(80)90166-9.","journal-title":"Dev Biol."},{"issue":"10","key":"9506_CR324","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1038\/nrd2359","volume":"6","author":"DR Clemmons","year":"2007","unstructured":"Clemmons DR. Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer. Nat Rev Drug Discov. 2007;6(10):821\u201333. https:\/\/doi.org\/10.1038\/nrd2359.","journal-title":"Nat Rev Drug Discov."},{"issue":"6","key":"9506_CR325","doi-asserted-by":"publisher","first-page":"R321","DOI":"10.1530\/ERC-13-0231","volume":"20","author":"C Livingstone","year":"2013","unstructured":"Livingstone C. IGF2 and cancer. Endocr Relat Cancer. 2013;20(6):R321\u201339. https:\/\/doi.org\/10.1530\/ERC-13-0231.","journal-title":"Endocr Relat Cancer."},{"issue":"7","key":"9506_CR326","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1007\/PL00000744","volume":"57","author":"TE Adams","year":"2000","unstructured":"Adams TE, Epa VC, Garrett TP, Ward CW. Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci. 2000;57(7):1050\u201393. https:\/\/doi.org\/10.1007\/PL00000744.","journal-title":"Cell Mol Life Sci."},{"issue":"12","key":"9506_CR327","doi-asserted-by":"publisher","first-page":"3503","DOI":"10.2527\/jas1989.67123503x","volume":"67","author":"CR Baumrucker","year":"1989","unstructured":"Baumrucker CR, Stemberger BH. Insulin and insulin-like growth factor-I stimulate DNA synthesis in bovine mammary tissue in vitro. J Anim Sci. 1989;67(12):3503\u201314. https:\/\/doi.org\/10.2527\/jas1989.67123503x.","journal-title":"J Anim Sci."},{"issue":"5","key":"9506_CR328","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s11626-998-0020-2","volume":"34","author":"RC Hovey","year":"1998","unstructured":"Hovey RC, MacKenzie DD, McFadden TB. The proliferation of mouse mammary epithelial cells in response to specific mitogens is modulated by the mammary fat pad in vitro. In Vitro Cell Dev Biol Anim. 1998;34(5):385\u201392. https:\/\/doi.org\/10.1007\/s11626-998-0020-2.","journal-title":"In Vitro Cell Dev Biol Anim."},{"issue":"6","key":"9506_CR329","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1210\/edrv.20.6.0382","volume":"20","author":"V Hwa","year":"1999","unstructured":"Hwa V, Oh Y, Rosenfeld RG. The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev. 1999;20(6):761\u201387. https:\/\/doi.org\/10.1210\/edrv.20.6.0382.","journal-title":"Endocr Rev."},{"issue":"34","key":"9506_CR330","doi-asserted-by":"publisher","first-page":"24588","DOI":"10.1074\/jbc.M509463200","volume":"281","author":"N Bhattacharyya","year":"2006","unstructured":"Bhattacharyya N, Pechhold K, Shahjee H, Zappala G, Elbi C, Raaka B, et al. Nonsecreted insulin-like growth factor binding protein-3 (IGFBP-3) can induce apoptosis in human prostate cancer cells by IGF-independent mechanisms without being concentrated in the nucleus. J Biol Chem. 2006;281(34):24588\u2013601. https:\/\/doi.org\/10.1074\/jbc.M509463200.","journal-title":"J Biol Chem."},{"issue":"6","key":"9506_CR331","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1210\/er.2001-0033","volume":"23","author":"SM Firth","year":"2002","unstructured":"Firth SM, Baxter RC. Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev. 2002;23(6):824\u201354. https:\/\/doi.org\/10.1210\/er.2001-0033.","journal-title":"Endocr Rev."},{"issue":"3 Pt 2","key":"9506_CR332","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/0092-8674(84)90457-4","volume":"39","author":"D Kalderon","year":"1984","unstructured":"Kalderon D, Roberts BL, Richardson WD, Smith AE. A short amino acid sequence able to specify nuclear location. Cell. 1984;39(3 Pt 2):499\u2013509. https:\/\/doi.org\/10.1016\/0092-8674(84)90457-4.","journal-title":"Cell."},{"issue":"4","key":"9506_CR333","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1210\/endo.138.4.5176","volume":"138","author":"W Li","year":"1997","unstructured":"Li W, Fawcett J, Widmer HR, Fielder PJ, Rabkin R, Keller GA. Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells. Endocrinology. 1997;138(4):1763\u20136. https:\/\/doi.org\/10.1210\/endo.138.4.5176.","journal-title":"Endocrinology."},{"issue":"1\u20132","key":"9506_CR334","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/s0739-7240(02)00149-2","volume":"23","author":"JW Blum","year":"2002","unstructured":"Blum JW, Baumrucker CR. Colostral and milk insulin-like growth factors and related substances: mammary gland and neonatal (intestinal and systemic) targets. Domest Anim Endocrinol. 2002;23(1\u20132):101\u201310. https:\/\/doi.org\/10.1016\/s0739-7240(02)00149-2.","journal-title":"Domest Anim Endocrinol."},{"issue":"43","key":"9506_CR335","doi-asserted-by":"publisher","first-page":"33607","DOI":"10.1074\/jbc.M002547200","volume":"275","author":"B Liu","year":"2000","unstructured":"Liu B, Lee HY, Weinzimer SA, Powell DR, Clifford JL, Kurie JM, et al. Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis. J Biol Chem. 2000;275(43):33607\u201313. https:\/\/doi.org\/10.1074\/jbc.M002547200.","journal-title":"J Biol Chem."},{"issue":"1","key":"9506_CR336","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.domaniend.2009.12.001","volume":"39","author":"Y Wang","year":"2010","unstructured":"Wang Y, Baumrucker CR. Retinoids, retinoid analogs, and lactoferrin interact and differentially affect cell viability of 2 bovine mammary cell types in vitro. Domest Anim Endocrinol. 2010;39(1):10\u201320. https:\/\/doi.org\/10.1016\/j.domaniend.2009.12.001.","journal-title":"Domest Anim Endocrinol."},{"issue":"4","key":"9506_CR337","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.domaniend.2005.07.009","volume":"30","author":"CR Baumrucker","year":"2006","unstructured":"Baumrucker CR, Schanbacher F, Shang Y, Green MH. Lactoferrin interaction with retinoid signaling: cell growth and apoptosis in mammary cells. Domest Anim Endocrinol. 2006;30(4):289\u2013303. https:\/\/doi.org\/10.1016\/j.domaniend.2005.07.009.","journal-title":"Domest Anim Endocrinol."},{"issue":"6","key":"9506_CR338","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1210\/edrv.18.6.0321","volume":"18","author":"S Rajaram","year":"1997","unstructured":"Rajaram S, Baylink DJ, Mohan S. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. Endocr Rev. 1997;18(6):801\u201331. https:\/\/doi.org\/10.1210\/edrv.18.6.0321.","journal-title":"Endocr Rev."},{"key":"9506_CR339","doi-asserted-by":"publisher","unstructured":"Guler HP, Zapf J, Schmid C, Froesch ER. Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates. Acta Endocrinol (Copenh). 1989;121(6):753\u20138. https:\/\/doi.org\/10.1530\/acta.0.1210753.","DOI":"10.1530\/acta.0.1210753"},{"issue":"1","key":"9506_CR340","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1210\/endo.131.1.1377125","volume":"131","author":"M Boes","year":"1992","unstructured":"Boes M, Booth BA, Sandra A, Dake BL, Bergold A, Bar RS. Insulin-like growth factor binding protein (IGFBP)4 accounts for the connective tissue distribution of endothelial cell IGFBPs perfused through the isolated heart. Endocrinology. 1992;131(1):327\u201330. https:\/\/doi.org\/10.1210\/endo.131.1.1377125.","journal-title":"Endocrinology."},{"issue":"1","key":"9506_CR341","doi-asserted-by":"publisher","first-page":"E32","DOI":"10.1152\/ajpendo.1998.275.1.E32","volume":"275","author":"A Sandra","year":"1998","unstructured":"Sandra A, Boes M, Dake BL, Stokes JB, Bar RS. Infused IGF-I\/IGFBP-3 complex causes glomerular localization of IGF-I in the rat kidney. Am J Physiol. 1998;275(1):E32\u20137. https:\/\/doi.org\/10.1152\/ajpendo.1998.275.1.E32.","journal-title":"Am J Physiol."},{"issue":"9","key":"9506_CR342","doi-asserted-by":"publisher","first-page":"3749","DOI":"10.1210\/endo.142.9.8353","volume":"142","author":"KL Knudtson","year":"2001","unstructured":"Knudtson KL, Boes M, Sandra A, Dake BL, Booth BA, Bar RS. Distribution of chimeric IGF binding protein (IGFBP)-3 and IGFBP-4 in the rat heart: importance of C-terminal basic region. Endocrinology. 2001;142(9):3749\u201355. https:\/\/doi.org\/10.1210\/endo.142.9.8353.","journal-title":"Endocrinology."},{"issue":"5","key":"9506_CR343","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.beem.2015.06.003","volume":"29","author":"MB Ranke","year":"2015","unstructured":"Ranke MB. Insulin-like growth factor binding-protein-3 (IGFBP-3). Best Pract Res Clin Endocrinol Metab. 2015;29(5):701\u201311. https:\/\/doi.org\/10.1016\/j.beem.2015.06.003.","journal-title":"Best Pract Res Clin Endocrinol Metab."},{"issue":"5","key":"9506_CR344","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.tem.2005.05.005","volume":"16","author":"LA Bach","year":"2005","unstructured":"Bach LA, Headey SJ, Norton RS. IGF-binding proteins\u2013the pieces are falling into place. Trends Endocrinol Metab. 2005;16(5):228\u201334. https:\/\/doi.org\/10.1016\/j.tem.2005.05.005.","journal-title":"Trends Endocrinol Metab."},{"issue":"5","key":"9506_CR345","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1038\/nrc3720","volume":"14","author":"RC Baxter","year":"2014","unstructured":"Baxter RC. IGF binding proteins in cancer: mechanistic and clinical insights. Nat Rev Cancer. 2014;14(5):329\u201341. https:\/\/doi.org\/10.1038\/nrc3720.","journal-title":"Nat Rev Cancer."},{"issue":"6","key":"9506_CR346","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1530\/eje.0.1320645","volume":"132","author":"J Zapf","year":"1995","unstructured":"Zapf J. Physiological role of the insulin-like growth factor binding proteins. Eur J Endocrinol. 1995;132(6):645\u201354. https:\/\/doi.org\/10.1530\/eje.0.1320645.","journal-title":"Eur J Endocrinol."},{"key":"9506_CR347","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/s0065-230x(08)60354-1","volume":"68","author":"H Werner","year":"1996","unstructured":"Werner H, LeRoith D. The role of the insulin-like growth factor system in human cancer. Adv Cancer Res. 1996;68:183\u2013223. https:\/\/doi.org\/10.1016\/s0065-230x(08)60354-1.","journal-title":"Adv Cancer Res."},{"issue":"6","key":"9506_CR348","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.2527\/1999.7761547x","volume":"77","author":"CA Gibson","year":"1999","unstructured":"Gibson CA, Staley MD, Baumrucker CR. Identification of IGF binding proteins in bovine milk and the demonstration of IGFBP-3 synthesis and release by bovine mammary epithelial cells. J Anim Sci. 1999;77(6):1547\u201357. https:\/\/doi.org\/10.2527\/1999.7761547x.","journal-title":"J Anim Sci."},{"issue":"6","key":"9506_CR349","doi-asserted-by":"publisher","first-page":"2538","DOI":"10.2527\/1991.6962538x","volume":"69","author":"JR Vega","year":"1991","unstructured":"Vega JR, Gibson CA, Skaar TC, Hadsell DL, Baumrucker CR. Insulin-like growth factor (IGF)-I and -II and IGF binding proteins in serum and mammary secretions during the dry period and early lactation in dairy cows. J Anim Sci. 1991;69(6):2538\u201347. https:\/\/doi.org\/10.2527\/1991.6962538x.","journal-title":"J Anim Sci."},{"issue":"25","key":"9506_CR350","doi-asserted-by":"publisher","first-page":"14676","DOI":"10.1074\/jbc.271.25.14676","volume":"271","author":"JL Fowlkes","year":"1996","unstructured":"Fowlkes JL, Serra DM. Characterization of glycosaminoglycan-binding domains present in insulin-like growth factor-binding protein-3. J Biol Chem. 1996;271(25):14676\u20139. https:\/\/doi.org\/10.1074\/jbc.271.25.14676.","journal-title":"J Biol Chem."},{"issue":"7","key":"9506_CR351","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/0968-0004(94)90004-3","volume":"19","author":"RT Radulescu","year":"1994","unstructured":"Radulescu RT. Nuclear localization signal in insulin-like growth factor-binding protein type 3. Trends Biochem Sci. 1994;19(7):278. https:\/\/doi.org\/10.1016\/0968-0004(94)90004-3.","journal-title":"Trends Biochem Sci."},{"issue":"1","key":"9506_CR352","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1023\/a:1009515232450","volume":"5","author":"CR Baumrucker","year":"2000","unstructured":"Baumrucker CR, Erondu NE. Insulin-like growth factor (IGF) system in the bovine mammary gland and milk. J Mammary Gland Biol Neoplasia. 2000;5(1):53\u201364. https:\/\/doi.org\/10.1023\/a:1009515232450. PMID: 10791768\u00a0","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"31","key":"9506_CR353","doi-asserted-by":"publisher","first-page":"23462","DOI":"10.1074\/jbc.M002208200","volume":"275","author":"LJ Schedlich","year":"2000","unstructured":"Schedlich LJ, Le Page SL, Firth SM, Briggs LJ, Jans DA, Baxter RC. Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit. J Biol Chem. 2000;275(31):23462\u201370. https:\/\/doi.org\/10.1074\/jbc.M002208200.","journal-title":"J Biol Chem."},{"issue":"4","key":"9506_CR354","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.1210\/jcem.86.4.7380","volume":"86","author":"SA Weinzimer","year":"2001","unstructured":"Weinzimer SA, Gibson TB, Collett-Solberg PF, Khare A, Liu B, Cohen P. Transferrin is an insulin-like growth factor-binding protein-3 binding protein. J Clin Endocrinol Metab. 2001;86(4):1806\u201313. https:\/\/doi.org\/10.1210\/jcem.86.4.7380.","journal-title":"J Clin Endocrinol Metab."},{"issue":"4","key":"9506_CR355","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/s0739-7240(03)00014-6","volume":"24","author":"CR Baumrucker","year":"2003","unstructured":"Baumrucker CR, Gibson CA, Schanbacher FL. Bovine lactoferrin binds to insulin-like growth factor-binding protein-3. Domest Anim Endocrinol. 2003;24(4):287\u2013303. https:\/\/doi.org\/10.1016\/s0739-7240(03)00014-6.","journal-title":"Domest Anim Endocrinol."},{"issue":"3","key":"9506_CR356","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/BF02018081","volume":"1","author":"JH Nuijens","year":"1996","unstructured":"Nuijens JH, van Berkel PH, Schanbacher FL. Structure and biological actions of lactoferrin. J Mammary Gland Biol Neoplasia. 1996;1(3):285\u201395. https:\/\/doi.org\/10.1007\/BF02018081.","journal-title":"J Mammary Gland Biol Neoplasia."},{"issue":"1","key":"9506_CR357","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1002\/jemt.10173","volume":"59","author":"LJ Schedlich","year":"2002","unstructured":"Schedlich LJ, Graham LD. Role of insulin-like growth factor binding protein-3 in breast cancer cell growth. Microsc Res Tech. 2002;59(1):12\u201322. https:\/\/doi.org\/10.1002\/jemt.10173.","journal-title":"Microsc Res Tech."},{"issue":"1","key":"9506_CR358","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1074\/jbc.M307316200","volume":"279","author":"KW Lee","year":"2004","unstructured":"Lee KW, Liu B, Ma L, Li H, Bang P, Koeffler HP, et al. Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization. J Biol Chem. 2004;279(1):469\u201376. https:\/\/doi.org\/10.1074\/jbc.M307316200.","journal-title":"J Biol Chem."},{"issue":"17","key":"9506_CR359","doi-asserted-by":"publisher","first-page":"4036","DOI":"10.1111\/febs.12372","volume":"280","author":"D Montarras","year":"2013","unstructured":"Montarras D, L\u2019Honore A, Buckingham M. Lying low but ready for action: the quiescent muscle satellite cell. FEBS J. 2013;280(17):4036\u201350. https:\/\/doi.org\/10.1111\/febs.12372.","journal-title":"FEBS J."},{"issue":"3","key":"9506_CR360","doi-asserted-by":"publisher","first-page":"222","DOI":"10.3109\/10409238.2013.770819","volume":"48","author":"J Vandooren","year":"2013","unstructured":"Vandooren J, Van den Steen PE, Opdenakker G. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decade. Crit Rev Biochem Mol Biol. 2013;48(3):222\u201372. https:\/\/doi.org\/10.3109\/10409238.2013.770819.","journal-title":"Crit Rev Biochem Mol Biol."},{"issue":"6","key":"9506_CR361","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1016\/j.cellsig.2014.02.015","volume":"26","author":"F Alghamdi","year":"2014","unstructured":"Alghamdi F, Guo M, Abdulkhalek S, Crawford N, Amith SR, Szewczuk MR. A novel insulin receptor-signaling platform and its link to insulin resistance and type 2 diabetes. Cell Signal. 2014;26(6):1355\u201368. https:\/\/doi.org\/10.1016\/j.cellsig.2014.02.015.","journal-title":"Cell Signal."},{"issue":"10","key":"9506_CR362","doi-asserted-by":"publisher","first-page":"3503","DOI":"10.1182\/blood.V89.10.3503","volume":"89","author":"N Borregaard","year":"1997","unstructured":"Borregaard N, Cowland JB. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood. 1997;89(10):3503\u201321.","journal-title":"Blood."},{"issue":"3\u20134","key":"9506_CR363","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.vetimm.2012.04.011","volume":"147","author":"TC Yu","year":"2012","unstructured":"Yu TC, Chen SE, Ho TH, Peh HC, Liu WB, Tiantong A, et al. Involvement of TNF-alpha and MAPK pathway in the intramammary MMP-9 release via degranulation of cow neutrophils during acute mammary gland involution. Vet Immunol Immunopathol. 2012;147(3\u20134):161\u20139. https:\/\/doi.org\/10.1016\/j.vetimm.2012.04.011.","journal-title":"Vet Immunol Immunopathol."},{"issue":"3","key":"9506_CR364","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1017\/S1751731114002420","volume":"9","author":"P Piamya","year":"2015","unstructured":"Piamya P, Tiantong A, Chen SE, Liu WB, Yu C, Nagahata H, et al. Fingerprinting of gelatinase subtypes for different topographic regions on non-retaining placenta of Holstein cows. Animal. 2015;9(3):490\u20139. https:\/\/doi.org\/10.1017\/S1751731114002420.","journal-title":"Animal."},{"key":"9506_CR365","unstructured":"Delphi Complete Works of Friedrich Nietzsche (Illustrated) By Friedrich Nietzsche. 2015. Delphi Publishing Limited. East Sussex, United Kingdom. ISBN: 9781910630969."}],"container-title":["Journal of Mammary Gland Biology and Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10911-021-09506-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10911-021-09506-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10911-021-09506-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T20:24:36Z","timestamp":1674591876000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10911-021-09506-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":365,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["9506"],"URL":"https:\/\/doi.org\/10.1007\/s10911-021-09506-2","relation":{},"ISSN":["1083-3021","1573-7039"],"issn-type":[{"value":"1083-3021","type":"print"},{"value":"1573-7039","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"29 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}