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Certainty of the evidence was rated with GRADE and the Evidence to Decision (EtD) framework was used to formulate recommendations. High or moderate certainty resulted in a recommendation \u201c<jats:italic>to advise\u201d<\/jats:italic>, low to very low in a recommendation \u201c<jats:italic>to consider\u201d<\/jats:italic>, unless other factors in the framework decided differently. <jats:italic>Results<\/jats:italic> An inventory of risk factors should be considered and an assessment of prognostic factors is advised. For prevention, physical exercises and education are advised, besides application of the evidence-based practical guidelines \u201clifting\u201d and \u201cwhole body vibration\u201d. The stepped-care approach to enhance work participation starts with the advice to stay active, facilitated by informing the worker, reducing workload, an action plan and a time-contingent increase of work participation for a defined amount of hours and tasks. If work participation has not improved within 6 weeks, additional treatments should be considered based on the present risk and prognostic factors: (1) physiotherapy or exercise therapy; (2) an intensive workplace-oriented program; or (3) cognitive behavioural therapy. After 12 weeks, multi-disciplinary (occupational) rehabilitation therapy need to be considered. <jats:italic>Conclusions<\/jats:italic> Based on systematic reviews and expert consensus, the good practice recommendations in this guideline focus on enhancing work participation among workers with LBP and LRS using a stepped-care approach to complement existing guidelines focusing on recovery and daily functioning.<\/jats:p>","DOI":"10.1007\/s10926-021-09993-4","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T14:02:55Z","timestamp":1627394575000},"page":"337-352","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The Dutch Multidisciplinary Occupational Health Guideline to Enhance Work Participation Among Low Back Pain and Lumbosacral Radicular Syndrome Patients"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4996-5690","authenticated-orcid":false,"given":"J. 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