{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T15:36:55Z","timestamp":1786721815455,"version":"build-2736575974"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Protein J"],"DOI":"10.1007\/s10930-026-10338-4","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:11:52Z","timestamp":1780063912000},"page":"549-557","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Screening of Small Peptide Against Ischemic Fatty-Acid Binding Protein (FABP)"],"prefix":"10.1007","volume":"45","author":[{"given":"Harshita","family":"Shand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumendu","family":"Patra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thirumurthy","family":"Madhavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvankar","family":"Ghorai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"key":"10338_CR1","doi-asserted-by":"publisher","first-page":"539","DOI":"10.3390\/ijerph22040539","volume":"22","author":"M Shannawaz","year":"2025","unstructured":"Shannawaz M, Rathi I, Shah N et al (2025) Prevalence of CVD among indian adult population: systematic review and meta-analysis. Int J Environ Res Public Health 22:539","journal-title":"Int J Environ Res Public Health"},{"key":"10338_CR2","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.3390\/cells13171471","volume":"13","author":"VR Netala","year":"2024","unstructured":"Netala VR, Teertam SK, Li H, Zhang Z (2024) A comprehensive review of cardiovascular disease management: cardiac biomarkers, imaging modalities, pharmacotherapy, surgical interventions, and herbal remedies. Cells 13:1471","journal-title":"Cells"},{"key":"10338_CR3","doi-asserted-by":"publisher","unstructured":"KimSJ,Mesquita FC, Hochman-Mendez C (2023) New biomarkers for cardiovascular disease. Tex Heart Inst J 50(5):e238178. https:\/\/doi.org\/10.14503\/THIJ-23-8178","DOI":"10.14503\/THIJ-23-8178"},{"key":"10338_CR4","doi-asserted-by":"publisher","first-page":"164","DOI":"10.3390\/jcm9010164","volume":"9","author":"R Rezar","year":"2020","unstructured":"Rezar R, Jirak P, Gschwandtner M et al (2020) Heart-type fatty acid-binding protein (H-FABP) and its role as a biomarker in heart failure: what do we know so far? J Clin Med 9:164","journal-title":"J Clin Med"},{"key":"10338_CR5","doi-asserted-by":"publisher","first-page":"e70878","DOI":"10.1002\/hsr2.70878","volume":"8","author":"A Nazir","year":"2025","unstructured":"Nazir A, Nazir A, Afzaal U et al (2025) Advancements in biomarkers for early detection and risk stratification of cardiovascular diseases\u2014a literature review. Health Sci Rep 8:e70878. https:\/\/doi.org\/10.1002\/hsr2.70878","journal-title":"Health Sci Rep"},{"key":"10338_CR6","first-page":"240","volume":"45","author":"A Nursalim","year":"2013","unstructured":"Nursalim A, Suryaatmadja M, Panggabean M (2013) Potential clinical application of novel cardiac biomarkers for acute myocardial infarction. Acta Med Indones 45:240\u2013250","journal-title":"Acta Med Indones"},{"key":"10338_CR7","doi-asserted-by":"publisher","first-page":"167","DOI":"10.4103\/1995-705X.201786","volume":"17","author":"R Hajar","year":"2016","unstructured":"Hajar R (2016) Evolution of myocardial infarction and its biomarkers: a historical perspective. Heart views 17:167\u2013172","journal-title":"Heart views"},{"key":"10338_CR8","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.ihj.2015.06.035","volume":"67","author":"A Vupputuri","year":"2015","unstructured":"Vupputuri A, Sekhar S, Krishnan S et al (2015) Heart-type fatty acid-binding protein (H-FABP) as an early diagnostic biomarker in patients with acute chest pain. Indian Heart J 67:538\u2013542","journal-title":"Indian Heart J"},{"key":"10338_CR9","first-page":"262","volume":"142","author":"A Esteves","year":"2006","unstructured":"Esteves A, Ehrlich R (2006) Invertebrate intracellular fatty acid binding proteins. Comp Biochem Physiol C Toxicol Pharmacol 142:262\u2013274","journal-title":"Comp Biochem Physiol C: Toxicol Pharmacol"},{"key":"10338_CR10","doi-asserted-by":"publisher","first-page":"6289","DOI":"10.3390\/ijms20246289","volume":"20","author":"N Trier","year":"2019","unstructured":"Trier N, Hansen P, Houen G (2019) Peptides, antibodies, peptide antibodies and more. Int J Mol Sci 20:6289","journal-title":"Int J Mol Sci"},{"key":"10338_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2017\/1827341","volume":"2017","author":"C De La Guardia","year":"2017","unstructured":"De La Guardia C, Quijada M, Lleonart R (2017) Phage-displayed peptides selected to bind envelope glycoprotein show antiviral activity against dengue virus serotype 2. Adv Virol 2017:1\u201311. https:\/\/doi.org\/10.1155\/2017\/1827341","journal-title":"Adv Virol"},{"key":"10338_CR12","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1002\/pmic.201100563","volume":"12","author":"P Braun","year":"2012","unstructured":"Braun P, Gingras A-C (2012) History of protein\u2013protein interactions: from egg-white to complex networks. Proteomics 12:1478\u20131498","journal-title":"Proteomics"},{"key":"10338_CR13","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.softx.2015.06.001","volume":"1","author":"MJ Abraham","year":"2015","unstructured":"Abraham MJ, Murtola T, Schulz R et al (2015) GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers. SoftwareX 1:19\u201325","journal-title":"SoftwareX"},{"key":"10338_CR14","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1006\/meth.1999.0852","volume":"19","author":"MM Pierce","year":"1999","unstructured":"Pierce MM, Raman CS, Nall BT (1999) Isothermal titration calorimetry of protein\u2013protein interactions. Methods 19:213\u2013221","journal-title":"Methods"},{"key":"10338_CR15","unstructured":"Schr\u00f6dinger L, DeLano W (2020) PyMOL. http:\/\/www.pymol.org\/pymol"},{"key":"10338_CR16","doi-asserted-by":"publisher","first-page":"105484","DOI":"10.1016\/j.micpath.2022.105484","volume":"165","author":"G Sethi","year":"2022","unstructured":"Sethi G, Sethi S, Krishna R (2022) Multi-epitope based vaccine design against Staphylococcus epidermidis: a subtractive proteomics and immunoinformatics approach. Microb Pathog 165:105484","journal-title":"Microb Pathog"},{"key":"10338_CR17","doi-asserted-by":"crossref","unstructured":"Green MR, Sambrook J (2018) The Hanahan method for preparation and transformation of competent Escherichia coli: high-efficiency transformation. Cold Spring Harbor Protoc 2018:pdb-prot101188","DOI":"10.1101\/pdb.prot101188"},{"key":"10338_CR18","doi-asserted-by":"publisher","first-page":"W365","DOI":"10.1093\/nar\/gkx407","volume":"45","author":"Y Yan","year":"2017","unstructured":"Yan Y, Zhang D, Zhou P et al (2017) HDOCK: a web server for protein\u2013protein and protein\u2013DNA\/RNA docking based on a hybrid strategy. Nucleic Acids Res 45:W365\u2013W373","journal-title":"Nucleic Acids Res"},{"key":"10338_CR19","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1007\/s40203-024-00251-y","volume":"12","author":"H Shand","year":"2024","unstructured":"Shand H, Patra S, Chandrasekhar B et al (2024) In-silico binding affinity of a phage display library screened novel peptide against various FABPs. Silico Pharmacol 12:76. https:\/\/doi.org\/10.1007\/s40203-024-00251-y","journal-title":"Silico Pharmacol"},{"key":"10338_CR20","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0301-4622(00)00227-1","volume":"89","author":"Z Zhang","year":"2001","unstructured":"Zhang Z, Zhu Y, Shi Y (2001) Molecular dynamics simulations of urea and thermal-induced denaturation of S-peptide analogue. Biophys Chem 89:145\u2013162","journal-title":"Biophys Chem"}],"container-title":["The Protein Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10930-026-10338-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10930-026-10338-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10930-026-10338-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T15:08:07Z","timestamp":1786720087000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10930-026-10338-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,29]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["10338"],"URL":"https:\/\/doi.org\/10.1007\/s10930-026-10338-4","relation":{},"ISSN":["1875-8355"],"issn-type":[{"value":"1875-8355","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,29]]},"assertion":[{"value":"8 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable. Recombinant H-FABP protein was used to conduct the study.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}}]}}