{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:13:33Z","timestamp":1766146413012,"version":"3.48.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Muscle Res Cell Motil"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s10974-025-09699-7","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T05:25:24Z","timestamp":1758864324000},"page":"463-476","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Regulation of Autonomic Motility in Human Gastric Muscle and the Gastroepiploic Artery by Stretch and pH"],"prefix":"10.1007","volume":"46","author":[{"given":"Dae Hoon","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Myoung","family":"Son","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chan Hyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hun Sik","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Bae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Xie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Chul","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo-Yung","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"issue":"5","key":"9699_CR1","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1038\/sj.bjp.0706084","volume":"144","author":"C Aalkjaer","year":"2005","unstructured":"Aalkjaer C, Nilsson H (2005) Vasomotion: cellular background for the oscillator and for the synchronization of smooth muscle cells. Br J Pharmacol 144(5):605\u2013616. https:\/\/doi.org\/10.1038\/sj.bjp.0706084","journal-title":"Br J Pharmacol"},{"issue":"3","key":"9699_CR2","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/j.1748-1716.2011.02320.x","volume":"202","author":"C Aalkjaer","year":"2011","unstructured":"Aalkjaer C, Boedtkjer D, Matchkov V (2011) Vasomotion \u2013 what is currently thought? Acta Physiol 202(3):253\u2013269. https:\/\/doi.org\/10.1111\/j.1748-1716.2011.02320.x","journal-title":"Acta Physiol"},{"issue":"4","key":"9699_CR3","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1530\/rep.1.00442","volume":"129","author":"X Bai","year":"2005","unstructured":"Bai X, Bugg GJ, Greenwood SL, Glazier JD, Sibley CP, Baker PN, Taggart MJ, Fyfe GK (2005) Expression of TASK and TREK, two-pore domain K+ channels, in human myometrium. Reproduction 129(4):525\u2013530. https:\/\/doi.org\/10.1530\/rep.1.00442","journal-title":"Reproduction"},{"key":"9699_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/nyas.12874","volume":"1352","author":"SG Brohawn","year":"2015","unstructured":"Brohawn SG (2015) How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. Ann N Y Acad Sci 1352:20\u201332. https:\/\/doi.org\/10.1111\/nyas.12874","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"9699_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.celrep.2019.08.075","volume":"29","author":"CD Cox","year":"2019","unstructured":"Cox CD, Bavi N, Martinac B (2019) Biophysical principles of ion-channel-mediated mechanosensory transduction. Cell Rep 29(1):1\u201312. https:\/\/doi.org\/10.1016\/j.celrep.2019.08.075","journal-title":"Cell Rep"},{"key":"9699_CR6","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/bs.apcsb.2015.12.002","volume":"104","author":"D Curr\u00f2","year":"2016","unstructured":"Curr\u00f2 D (2016) The modulation of potassium channels in the smooth muscle as a therapeutic strategy for disorders of the gastrointestinal tract. Adv Protein Chem Struct Biol 104:263\u2013305. https:\/\/doi.org\/10.1016\/bs.apcsb.2015.12.002","journal-title":"Adv Protein Chem Struct Biol"},{"issue":"1\u20132","key":"9699_CR7","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/s0165-1838(97)00087-8","volume":"67","author":"J Fujimura","year":"1997","unstructured":"Fujimura J, Camilleri M, Low PA, Novak V, Novak P, Opfer-Gehrking TL (1997) Effect of perturbations and a meal on superior mesenteric artery flow in patients with orthostatic hypotension. J Auton Nerv Syst 67(1\u20132):15\u201323. https:\/\/doi.org\/10.1016\/s0165-1838(97)00087-8","journal-title":"J Auton Nerv Syst"},{"issue":"6","key":"9699_CR8","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1002\/nau.25316","volume":"43","author":"L Grundy","year":"2024","unstructured":"Grundy L, Wyndaele JJ, Hashitani H, Vahabi B, Wein A, Abrams P, Chakrabarty B, Fry CH (2024) How does the lower urinary tract contribute to bladder sensation? ICI-RS 2023. Neurourol Urodyn 43(6):1293\u20131302. https:\/\/doi.org\/10.1002\/nau.25316","journal-title":"Neurourol Urodyn"},{"issue":"3","key":"9699_CR9","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1113\/jphysiol.2005.086405","volume":"566","author":"RE Haddock","year":"2005","unstructured":"Haddock RE, Hill CE (2005) Rhythmicity in arterial smooth muscle. J Physiol 566(3):645\u2013656. https:\/\/doi.org\/10.1113\/jphysiol.2005.086405","journal-title":"J Physiol"},{"issue":"6","key":"9699_CR10","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1161\/01.RES.0000143014.04535.a3","volume":"95","author":"MI Harhun","year":"2004","unstructured":"Harhun MI, Gordienko DV, Povstyan OV, Moss RF, Bolton TB (2004) Function of interstitial cells of Cajal in the rabbit portal vein. Circ Res 95(6):619\u2013626. https:\/\/doi.org\/10.1161\/01.RES.0000143014.04535.a3","journal-title":"Circ Res"},{"issue":"3","key":"9699_CR11","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1113\/JP271438","volume":"594","author":"H Hashitani","year":"2016","unstructured":"Hashitani H, Lang RJ (2016) Spontaneous activity in the microvasculature of visceral organs: role of pericytes and voltage-dependent Ca(2+) channels. J Physiol 594(3):555\u2013565. https:\/\/doi.org\/10.1113\/JP271438","journal-title":"J Physiol"},{"issue":"4","key":"9699_CR12","doi-asserted-by":"publisher","first-page":"359","DOI":"10.4196\/kjpp.2013.17.4.359","volume":"17","author":"SH Hong","year":"2013","unstructured":"Hong SH, Sung R, Kim YC, Suzuki H, Choi W, Park YJ, Ji IW, Kim CH, Myungb SC, Lee MY, Kang TM, You RY, Lee KJ, Lim SW, Yun HY, Song YJ, Xu WX, KimHS LSJ (2013) Mechanism of relaxation via TASK-2 channels in uterine circular muscle of mouse. Kor J Physiol Pharmacol 17(4):359\u2013365. https:\/\/doi.org\/10.4196\/kjpp.2013.17.4.359","journal-title":"Kor J Physiol Pharmacol"},{"issue":"6","key":"9699_CR100","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1540\/jsmr.41.313","volume":"41","author":"A Hotta","year":"2005","unstructured":"Hotta A, Kim YC, Nakamura E, Kito Y, Yamamoto Y, Suzuki H (2005) Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum. J Smooth Muscle Res 41(6):313\u2013327. https:\/\/doi.org\/10.1540\/jsmr.41.313","journal-title":"J Smooth Muscle Res"},{"issue":"1","key":"9699_CR13","doi-asserted-by":"publisher","first-page":"G1","DOI":"10.1152\/ajpgi.90380.2008","volume":"296","author":"JD Huizinga","year":"2009","unstructured":"Huizinga JD, Lammers WJ (2009) Gut peristalsis is governed by a multitude of cooperating mechanisms. Am J Physiol 296(1):G1\u2013G8. https:\/\/doi.org\/10.1152\/ajpgi.90380.2008","journal-title":"Am J Physiol"},{"key":"9699_CR14","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/373347a0","volume":"373","author":"JD Huizinga","year":"1995","unstructured":"Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A (1995) W\/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373:347\u2013349. https:\/\/doi.org\/10.1038\/373347a0","journal-title":"Nature"},{"issue":"11","key":"9699_CR15","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1007\/s12094-013-1022-4","volume":"15","author":"A Innamaa","year":"2013","unstructured":"Innamaa A, Jackson L, Asher V, Schalkwyk G, Warren A, Keightley A, Hay D, Bali A, Sowter H, Khan R (2013) Expression and effects of modulation of the K2P potassium channels TREK-1 (KCNK2) and TREK-2 (KCNK10) in the normal human ovary and epithelial ovarian cancer. Clin Transl Oncol 15(11):910\u2013918. https:\/\/doi.org\/10.1007\/s12094-013-1022-4","journal-title":"Clin Transl Oncol"},{"issue":"9","key":"9699_CR16","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.1002\/jcp.31067","volume":"238","author":"DH Kim","year":"2023","unstructured":"Kim DH, Choi JY, Kim SM, Son SM, Choi SY, Koo B, Rah CS, Kim CH, Choi W, Lee SJ, Yun HY, Kim YC (2023) Vasomotion in human arteries and their regulations based on ion channel regulations: 10 years study. J Cell Physiol 238(9):2076\u20132089. https:\/\/doi.org\/10.1002\/jcp.31067","journal-title":"J Cell Physiol"},{"issue":"Suppl1","key":"9699_CR17","doi-asserted-by":"publisher","first-page":"e49","DOI":"10.1097\/01.hjh.0000499981.55788.a6","volume":"34","author":"YC Kim","year":"2016","unstructured":"Kim YC, Kim DH, Lee SE, Kim CH, Choi W, Lee SJ, Yun HY, Kim YC (2016) Physiological regulation of vasomotion by intracellular atp-mediated system in human artery. J Hypertens 34(Suppl1):e49. https:\/\/doi.org\/10.1097\/01.hjh.0000499981.55788.a6","journal-title":"J Hypertens"},{"issue":"3","key":"9699_CR18","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1113\/jphysiol.2002.018796","volume":"541","author":"YC Km","year":"2002","unstructured":"Kim YC, Koh SD, Sanders KM (2002) Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine. J Physiol 541(3):797\u2013810. https:\/\/doi.org\/10.1113\/jphysiol.2002.018796","journal-title":"J Physiol"},{"key":"9699_CR19","doi-asserted-by":"publisher","first-page":"44338","DOI":"10.1074\/jbc.M108125200","volume":"276","author":"SD Koh","year":"2001","unstructured":"Koh SD, Monaghan K, Sergeant GP, Ro S, Walker RL, Sanders KM, Horowitz B et al (2001) TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase. An essential role in smooth muscle inhibitory neurotransmission. J Biol Chem 276:44338\u201344346. https:\/\/doi.org\/10.1074\/jbc.M108125200","journal-title":"J Biol Chem"},{"issue":"5","key":"9699_CR20","doi-asserted-by":"publisher","first-page":"547","DOI":"10.4196\/kjpp.2016.20.5.547","volume":"20","author":"KS Kyeong","year":"2016","unstructured":"Kyeong KS, Hong SH, Kim YC, Cho W, Myung SC, Lee MY, You RY, Kim CH, Kwon SY, Suzuki H, Park YJ, Jeong EH, Kim HS, Kim H, Lim SW, Xu WX, Lee SJ, Ji IW (2016) Myometrial relaxation of mice via expression of two pore domain acid sensitive K(+) (TASK-2) channels. Korean J Physiol Pharmacol 20(5):547\u2013556. https:\/\/doi.org\/10.4196\/kjpp.2016.20.5.547","journal-title":"Korean J Physiol Pharmacol"},{"issue":"3\u20134","key":"9699_CR21","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/BF00374771","volume":"426","author":"SH Lee","year":"1994","unstructured":"Lee SH, Earm YE (1994) Caffeine induces periodic oscillations of Ca2+-activated K+ current in pulmonary arterial smooth muscle cells. Pflugers Arch 426(3\u20134):189\u2013198. https:\/\/doi.org\/10.1007\/BF00374771","journal-title":"Pflugers Arch"},{"key":"9699_CR22","unstructured":"Lee JY, Son SM, Choi W, Kim HS, Kim KB, Kang SH, Jung HJ, Yun HY, Kim YC (2024) Regulatory Mechanisms of Acetylcholine Induced Phasic Contractions in Gastric Smooth Muscles. In submission"},{"issue":"14","key":"9699_CR23","doi-asserted-by":"publisher","first-page":"3013","DOI":"10.1113\/jphysiol.2014.271718","volume":"592","author":"Q Lei","year":"2014","unstructured":"Lei Q, Pan XQ, Chang S, Malkowicz SB, Guzzo TJ, Malykhina AP (2014) Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel. J Physiol 592(14):3013\u20133030. https:\/\/doi.org\/10.1113\/jphysiol.2014.271718","journal-title":"J Physiol"},{"issue":"12","key":"9699_CR24","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1111\/nmo.12223","volume":"25","author":"RG Lentle","year":"2013","unstructured":"Lentle RG, Reynolds GW, Janssen PW (2013) Gastrointestinal tone; its genesis and contribution to the physical processes of digestion. Neurogastroenterol Motil 25(12):931\u2013942. https:\/\/doi.org\/10.1111\/nmo.12223","journal-title":"Neurogastroenterol Motil"},{"issue":"5","key":"9699_CR25","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1002\/j.1460-2075.1996.tb00437.x","volume":"15","author":"F Lesage","year":"1996","unstructured":"Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, Romey G, Barhanin J (1996) TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure. EMBO J 15(5):1004\u20131011","journal-title":"EMBO J"},{"issue":"2","key":"9699_CR26","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s00424-015-1752-y","volume":"468","author":"R Mitsui","year":"2016","unstructured":"Mitsui R, Hashitani H (2016) Mechanisms underlying spontaneous constrictions of postcapillary venules in the rat stomach. Pflugers Arch 468(2):279\u2013291. https:\/\/doi.org\/10.1007\/s00424-015-1752-y","journal-title":"Pflugers Arch"},{"issue":"5","key":"9699_CR27","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1113\/jphysiol.2010.203869","volume":"589","author":"K Monaghan","year":"2011","unstructured":"Monaghan K, Baker SA, Dwyer L, Hatton WC, Park KS, Sanders KM, Koh SD (2011) The stretch-dependent potassium channel TREK-1 and its function in murine myometrium. J Physiol 589(5):1221\u20131233. https:\/\/doi.org\/10.1113\/jphysiol.2010.203869","journal-title":"J Physiol"},{"issue":"8","key":"9699_CR28","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/j.tins.2012.04.002","volume":"35","author":"B Nilius","year":"2012","unstructured":"Nilius B, Honor E (2012) Sensing pressure with ion channels. Trends Neurosci 35(8):477\u2013486. https:\/\/doi.org\/10.1016\/j.tins.2012.04.002","journal-title":"Trends Neurosci"},{"issue":"6","key":"9699_CR29","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1210\/en.2012-2142","volume":"154","author":"N Nishikawa","year":"2013","unstructured":"Nishikawa N, Kanematsu A, Negoro H, Imamura M, Sugino Y, Okinami T, Yoshimura K, Hashitani H, Ogawa O (2013) PthrP is endogenous relaxant for spontaneous smooth muscle contraction in urinary bladder of female rat. Endocrinology 154(6):2058\u20132068. https:\/\/doi.org\/10.1210\/en.2012-2142","journal-title":"Endocrinology"},{"issue":"1\u20132","key":"9699_CR30","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/s0005-2736(02)00597-7","volume":"1566","author":"AD O\u2019Connell","year":"2002","unstructured":"O\u2019Connell AD, Morton MJ, Hunter M (2002) Two-pore domain K+ channels-molecular sensors. Biochim Biophys Acta 1566(1\u20132):152\u2013161. https:\/\/doi.org\/10.1016\/s0005-2736(02)00597-7","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"9699_CR31","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1152\/jn.00785.2001","volume":"87","author":"AJ Page","year":"2002","unstructured":"Page AJ, Martin CM, Blackshaw LA (2002) Vagal mechanoreceptors and chemoreceptors in mouse stomach and esophagus. J Neurophysiol 87(4):2095\u20132103","journal-title":"J Neurophysiol"},{"issue":"2","key":"9699_CR32","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s00424-007-0204-8","volume":"454","author":"JK Park","year":"2007","unstructured":"Park JK, Kim YC, Sim JH, Choi MY, Choi W, Hwang KK, Cho MC, Kim KW, Lim SW, Lee SJ (2007) Regulation of membrane excitability by intracellular pH (pHi) changers through Ca2+-activated K+ current (BK channel) in single smooth muscle cells from rabbit basilar artery. Pflugers Arch 454(2):307\u2013319. https:\/\/doi.org\/10.1007\/s00424-007-0204-8","journal-title":"Pflugers Arch"},{"issue":"6","key":"9699_CR33","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/s0166-2236(00)01810-5","volume":"24","author":"AJ Patel","year":"2001","unstructured":"Patel AJ, Honore E (2001) Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci 24(6):339\u2013346. https:\/\/doi.org\/10.1016\/s0166-2236(00)01810-5","journal-title":"Trends Neurosci"},{"issue":"2","key":"9699_CR34","doi-asserted-by":"publisher","first-page":"213","DOI":"10.5056\/jnm15186","volume":"22","author":"BA Perrino","year":"2016","unstructured":"Perrino BA (2016) Calcium sensitization mechanisms in gastrointestinal smooth muscles. J Neurogastroenterol Motil 22(2):213\u2013225. https:\/\/doi.org\/10.5056\/jnm15186","journal-title":"J Neurogastroenterol Motil"},{"issue":"2","key":"9699_CR35","doi-asserted-by":"publisher","first-page":"F535","DOI":"10.1152\/ajprenal.00638.2016","volume":"313","author":"RH Pineda","year":"2017","unstructured":"Pineda RH, Nedumaran B, Hypolite J, Pan XQ, Wison S, Meacham RB, Malykhina AP (2017) Altered expression and modulation of the two-pore-domain (K(2P)) mechanogated potassium channel TREK-1 in overactive human detrusor. Am J Physiol 313(2):F535\u2013F546. https:\/\/doi.org\/10.1152\/ajprenal.00638.2016","journal-title":"Am J Physiol"},{"issue":"4","key":"9699_CR36","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/s0143-4160(02)00197-5","volume":"33","author":"OV Povstyan","year":"2003","unstructured":"Povstyan OV, Gordienko DV, Harhun MI, Bolton TB (2003) Identification of interstitial cells of Cajal in the rabbit portal vein. Cell Calcium 33(4):223\u2013239. https:\/\/doi.org\/10.1016\/s0143-4160(02)00197-5","journal-title":"Cell Calcium"},{"issue":"4","key":"9699_CR37","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1111\/j.1582-4934.2007.00066.x","volume":"11","author":"V Pucovsky","year":"2007","unstructured":"Pucovsky V, Harhun MI, Povstyan OV, Gordienko DV, Moss RF, Bolton TB (2007) Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell. J Cell Mol Med 11(4):764\u2013775. https:\/\/doi.org\/10.1111\/j.1582-4934.2007.00066.x","journal-title":"J Cell Mol Med"},{"key":"9699_CR38","first-page":"891","volume":"2","author":"S Ram\u00f3n y Cajal","year":"1911","unstructured":"Ram\u00f3n y Cajal S (1911) Histologie du syst\u00e8me nerveux de l\u2019homme et des vert\u00e9br\u00e9s. Maloine 2:891\u2013942","journal-title":"Maloine"},{"key":"9699_CR39","unstructured":"Ram\u00f3n y Cajal, S (1899) Textura del sistema nervioso del hombre y de los vertebrados, Imprenta y librer\u00eda de Nicol\u00e1s Moya, Vol. 2. Madrid."},{"issue":"2","key":"9699_CR40","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/s0022-510x(98)00276-7","volume":"161","author":"P Rossi","year":"1998","unstructured":"Rossi P, Andriesse GI, Oey PL, Wieneke GH, Roelofs JM, Akkermans LM (1998) Stomach distension increases efferent muscle sympathetic nerve activity and blood pressure in healthy humans. J Neurol Sci 161(2):148\u2013155. https:\/\/doi.org\/10.1016\/s0022-510x(98)00276-7","journal-title":"J Neurol Sci"},{"issue":"3","key":"9699_CR41","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1152\/physrev.00037.2013","volume":"94","author":"KM Sanders","year":"2014","unstructured":"Sanders KM, Ward SM, Koh SD (2014) Interstitial cells: regulators of smooth muscle function. Physiol Rev 94(3):859\u2013907. https:\/\/doi.org\/10.1152\/physrev.00037.2013","journal-title":"Physiol Rev"},{"issue":"4","key":"9699_CR42","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1097\/00005344-200404000-00009","volume":"43","author":"A Schuster","year":"2004","unstructured":"Schuster A, Lamboley M, Grange C, Oishi H, Beny JL, Stergiopulos N, Meister JJ (2004) Calcium dynamics and vasomotion in rat mesenteric arteries. J Cardiovasc Pharmacol 43(4):439\u2013548. https:\/\/doi.org\/10.1097\/00005344-200404000-00009","journal-title":"J Cardiovasc Pharmacol"},{"issue":"1","key":"9699_CR43","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1161\/01.atv.21.1.28","volume":"21","author":"CG Sobey","year":"2001","unstructured":"Sobey CG (2001) Potassium channel function in vascular disease. Arterioscler Thromb Vasc Biol 21(1):28\u201338. https:\/\/doi.org\/10.1161\/01.atv.21.1.28","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"Pt B","key":"9699_CR44","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.brainres.2018.02.039","volume":"1693","author":"AJ Treichel","year":"2018","unstructured":"Treichel AJ, Farrugia G, Beyder A (2018) The touchy business of gastrointestinal (GI) mechanosensitivity. Brain Res 1693(Pt B):197\u2013200. https:\/\/doi.org\/10.1016\/j.brainres.2018.02.039","journal-title":"Brain Res"},{"issue":"Pt 2","key":"9699_CR45","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1113\/jphysiol.2003.056580","volume":"555","author":"NP van Orshoven","year":"2004","unstructured":"van Orshoven NP, Oey PL, van Schelven LJ, Roelofs JM, Jansen PA, Akkermans LM (2004) Effect of gastric distension on cardiovascular parameters: gastrovascular reflex is attenuated in the elderly. J Physiol 555(Pt 2):573\u2013583. https:\/\/doi.org\/10.1113\/jphysiol.2003.056580","journal-title":"J Physiol"},{"key":"9699_CR105","doi-asserted-by":"publisher","unstructured":"Ward SM, Burns AJ, Torihashi S, Harney SC, Sanders KM (1995) Impaired development of interstitial cells and intestinal electrical rhythmicity in steel mutants. Am J Physiol. 269:C1577-C1585. https:\/\/doi.org\/10.1152\/ajpcell.1995.269.6.C1577","DOI":"10.1152\/ajpcell.1995.269.6.C1577"},{"issue":"1\u20134","key":"9699_CR46","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1152\/advan.00025.2003","volume":"27","author":"RC Webb","year":"2003","unstructured":"Webb RC (2003) Smooth muscle contraction and relaxation. Adv Physiol Educ 27(1\u20134):201\u2013206. https:\/\/doi.org\/10.1152\/advan.00025.2003","journal-title":"Adv Physiol Educ"},{"key":"9699_CR47","unstructured":"Yun HY, Kim DH, Son SM, Choi W, Lee SE, Kim KB, Bae JW, Kim YC (2024) Vasomotion and its regulation by second messengers and ionic channels in human gastric artery. In submission"},{"issue":"9","key":"9699_CR48","doi-asserted-by":"publisher","first-page":"e356","DOI":"10.1111\/j.1365-2982.2011.01753.x","volume":"23","author":"RX Zhang","year":"2011","unstructured":"Zhang RX, Wang XY, Chen D, Huizinga JD (2011) Role of interstitial cells of Cajal in the generation and modulation of motor activity induced by cholinergic neurotransmission in the stomach. Neurogastroenterol Motil 23(9):e356\u2013e371. https:\/\/doi.org\/10.1111\/j.1365-2982.2011.01753.x","journal-title":"Neurogastroenterol Motil"},{"issue":"21","key":"9699_CR49","doi-asserted-by":"publisher","first-page":"18460","DOI":"10.18632\/oncotarget.3782","volume":"6","author":"GM Zhang","year":"2015","unstructured":"Zhang GM, Wan FN, Qin XJ, Cao DL, Zhang HL, Yao Zhu, Bo Dai, Shi GH, Ye DW (2015) Prognostic significance of the TREK-1 K2P potassium channels in prostate cancer. Oncotarget 6(21):18460\u201318468. https:\/\/doi.org\/10.18632\/oncotarget.3782","journal-title":"Oncotarget"}],"container-title":["Journal of Muscle Research and Cell Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10974-025-09699-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10974-025-09699-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10974-025-09699-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:08:30Z","timestamp":1766146110000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10974-025-09699-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,26]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["9699"],"URL":"https:\/\/doi.org\/10.1007\/s10974-025-09699-7","relation":{},"ISSN":["0142-4319","1573-2657"],"issn-type":[{"type":"print","value":"0142-4319"},{"type":"electronic","value":"1573-2657"}],"subject":[],"published":{"date-parts":[[2025,9,26]]},"assertion":[{"value":"20 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interests"}}]}}