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Male mice (10\u201322\u00a0weeks old) were fed water and food ad libitum and housed in a thermally controlled room at 22\u201326\u00a0\u00b0C with a 12-h light\/dark cycle. Muscles were excised under anesthesia using an intraperitoneal injection of mixed anesthetic agents (0.4\u00a0mg\/kg body wt medetomidine, 2.0\u00a0mg\/kg body wt midazolam, and 2.5\u00a0mg\/kg body wt butorphanol) (Kawai et al. ). At the end of experiments, mice were euthanized with an overdose of isoflurane.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}