{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T12:18:45Z","timestamp":1792239525122,"version":"4.4.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Matern Child Health J"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1007\/s10995-015-1914-8","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T07:56:41Z","timestamp":1450684601000},"page":"833-842","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Pregnancy and Birth Outcomes Among Primiparae at Very Advanced Maternal Age: At What Price?"],"prefix":"10.1007","volume":"20","author":[{"given":"Alon","family":"Ben-David","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saralee","family":"Glasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyal","family":"Schiff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliza Segev","family":"Zahav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Boyko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liat","family":"Lerner-Geva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"issue":"19","key":"1914_CR1","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1056\/NEJMp048087","volume":"351","author":"LJ Heffner","year":"2004","unstructured":"Heffner, L. J. (2004). Advanced maternal age\u2014how old is too old. New England Journal of Medicine, 351(19), 1927\u20131929.","journal-title":"New England Journal of Medicine"},{"key":"1914_CR2","volume-title":"Delayed childbearing: More women are having their first child later in life.","author":"T Mathews","year":"2009","unstructured":"Mathews, T., & Hamilton, B. (2009). Delayed childbearing: More women are having their first child later in life.. USA: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics."},{"key":"1914_CR3","volume-title":"Health in Israel: Selected data 2010","author":"Ministry of Health","year":"2010","unstructured":"Ministry of Health. (2010). Health in Israel: Selected data 2010. Jerusalem: Ministry of Health."},{"issue":"2","key":"1914_CR4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1472-6483(10)61718-X","volume":"6","author":"S Antinori","year":"2003","unstructured":"Antinori, S., Gholami, G., Versaci, C., Cerusico, F., Dani, L., Antinori, M., et al. (2003). Obstetric and prenatal outcome in menopausal women: A 12-year clinical study. Reproductive biomedicine online, 6(2), 257\u2013261.","journal-title":"Reproductive biomedicine online"},{"issue":"18","key":"1914_CR5","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1001\/jama.288.18.2320","volume":"288","author":"RJ Paulson","year":"2002","unstructured":"Paulson, R. J., Boostanfar, R., Saadat, P., Mor, E., Tourgeman, D. E., Slater, C. C., et al. (2002). Pregnancy in the sixth decade of life: Obstetric outcomes in women of advanced reproductive age. JAMA, 288(18), 2320\u20132323.","journal-title":"JAMA"},{"issue":"3 Pt 1","key":"1914_CR6","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1053\/ob.1996.v175.a74402","volume":"175","author":"GA Dildy","year":"1996","unstructured":"Dildy, G. A., Jackson, G. M., Fowers, G. K., Oshiro, B. T., Varner, M. W., & Clark, S. L. (1996). Very advanced maternal age: Pregnancy after age 45. American Journal of Obstetrics and Gynecology, 175(3 Pt 1), 668\u2013674.","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"5 Pt 1","key":"1914_CR7","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/01.AOG.0000158118.75532.51","volume":"105","author":"J Cleary-Goldman","year":"2005","unstructured":"Cleary-Goldman, J., Malone, F. D., Vidaver, J., Ball, R. H., Nyberg, D. A., Comstock, C. H., et al. (2005). Impact of maternal age on obstetric outcome. Obstetrics and Gynecology, 105(5 Pt 1), 983\u2013990.","journal-title":"Obstetrics and Gynecology"},{"issue":"6","key":"1914_CR8","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1016\/j.fertnstert.2009.04.029","volume":"91","author":"GM Chambers","year":"2009","unstructured":"Chambers, G. M., Sullivan, E. A., Ishihara, O., Chapman, M. G., & Adamson, G. D. (2009). The economic impact of assisted reproductive technology: A review of selected developed countries. Fertility and Sterility, 91(6), 2281\u20132294.","journal-title":"Fertility and Sterility"},{"issue":"1","key":"1914_CR9","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1471-2393-13-80","volume":"13","author":"MC Carolan","year":"2013","unstructured":"Carolan, M. C., Davey, M.-A., Biro, M., & Kealy, M. (2013). Very advanced maternal age and morbidity in Victoria, Australia: A population based study. BMC Pregnancy Childbirth, 13(1), 80.","journal-title":"BMC Pregnancy Childbirth"},{"issue":"4","key":"1914_CR10","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/01.AOG.0000140682.63746.be","volume":"104","author":"B Jacobsson","year":"2004","unstructured":"Jacobsson, B., Ladfors, L., & Milsom, I. (2004). Advanced maternal age and adverse perinatal outcome. Obstetrics and Gynecology, 104(4), 727\u2013733.","journal-title":"Obstetrics and Gynecology"},{"issue":"3","key":"1914_CR11","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/humrep\/der469","volume":"27","author":"C Ray Le","year":"2012","unstructured":"Le Ray, C., Scherier, S., Anselem, O., Marszalek, A., Tsatsaris, V., Cabrol, D., & Goffinet, F. (2012). Association between oocyte donation and maternal and perinatal outcomes in women aged 43\u00a0years or older. Human Reproduction, 27(3), 896\u2013901.","journal-title":"Human Reproduction"},{"issue":"3","key":"1914_CR12","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/1471-0528.12415","volume":"121","author":"R Klemetti","year":"2014","unstructured":"Klemetti, R., Gissler, M., Sainio, S., & Hemminki, E. (2014). Associations of maternal age with maternity care use and birth outcomes in primiparous women: A comparison of results in 1991 and 2008 in Finland. BJOG, 121(3), 356\u2013362.","journal-title":"BJOG"},{"key":"1914_CR13","unstructured":"National Helath Insurance Law, 1994. Book of laws, 1469 Page 156 Available from: http:\/\/fs.knesset.gov.il\/\/13\/law\/13_lsr_211132.PDF . Accessed 21 Jan 2015 [in Hebrew]"},{"key":"1914_CR14","doi-asserted-by":"crossref","unstructured":"Sullivan, E., Zegers-Hochschild, F., Mansour, R., Ishihara, O., de Mouzon, J., Nygren, K., & Adamson, G. (2013). International Committee for Monitoring Assisted Reproductive Technologies (ICMART) world report: Assisted reproductive technology 2004. Human Reproduction: det036.","DOI":"10.1093\/humrep\/det036"},{"issue":"8","key":"1914_CR15","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1016\/j.fertnstert.2011.02.031","volume":"95","author":"S Glasser","year":"2011","unstructured":"Glasser, S., Segev-Zahav, A., Fortinsky, P., Gedal-Beer, D., Schiff, E., & Lerner-Geva, L. (2011). Primiparity at very advanced maternal age (>\/=45\u00a0years). Fertility and Sterility, 95(8), 2548\u20132551.","journal-title":"Fertility and Sterility"},{"issue":"6","key":"1914_CR16","doi-asserted-by":"crossref","first-page":"e551","DOI":"10.1016\/j.ajog.2010.07.039","volume":"203","author":"Y Yogev","year":"2010","unstructured":"Yogev, Y., Melamed, N., Bardin, R., Tenenbaum-Gavish, K., Ben-Shitrit, G., & Ben-Haroush, A. (2010). Pregnancy outcome at extremely advanced maternal age. American Journal of Obstetrics and Gynecology, 203(6), e551\u2013e558.","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"11","key":"1914_CR17","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.3109\/14767058.2012.684108","volume":"25","author":"I Laskov","year":"2012","unstructured":"Laskov, I., Birnbaum, R., Maslovitz, S., Kupferminc, M., Lessing, J., & Many, A. (2012). Outcome of singleton pregnancy in women\u00a0>\/=45\u00a0years old: a retrospective cohort study. Journal of Maternal-Fetal & Neonatal Medicine, 25(11), 2190\u20132193.","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"7","key":"1914_CR18","doi-asserted-by":"crossref","first-page":"669","DOI":"10.3109\/14767058.2012.746298","volume":"26","author":"I Laskov","year":"2013","unstructured":"Laskov, I., Michaan, N., Cohen, A., Tsafrir, Z., Maslovitz, S., Kupferminc, M., Lessing, J., & Many, A. (2013). Outcome of twin pregnancy in women\u00a0>\/=45\u00a0years old: A retrospective cohort study. Journal of Maternal-Fetal & Neonatal Medicine, 26(7), 669\u2013672.","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"5","key":"1914_CR19","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1097\/01.AOG.0000240139.46018.bd","volume":"108","author":"MJ Simchen","year":"2006","unstructured":"Simchen, M. J., Yinon, Y., Moran, O., Schiff, E., & Sivan, E. (2006). Pregnancy outcome after age 50. Obstetrics and Gynecology, 108(5), 1084\u20131088.","journal-title":"Obstetrics and Gynecology"},{"issue":"7","key":"1914_CR20","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0002-9378(82)90349-0","volume":"144","author":"MW Carpenter","year":"1982","unstructured":"Carpenter, M. W., & Coustan, D. R. (1982). Criteria for screening tests for gestational diabetes. American Journal of Obstetrics and Gynecology, 144(7), 768\u2013773.","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"5","key":"1914_CR21","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1097\/01.AOG.0000437382.03963.88","volume":"122","author":"American College of Obstetricians and Gynecologists","year":"2013","unstructured":"American College of Obstetricians and Gynecologists. (2013). Hypertension in pregnancy. Report of the American college of obstetricians and gynecologists\u2019 task force on hypertension in pregnancy. Obstetrics and Gynecology, 122(5), 1122.","journal-title":"Obstetrics and Gynecology"},{"issue":"5","key":"1914_CR22","first-page":"311","volume":"7","author":"S Dollberg","year":"2005","unstructured":"Dollberg, S., Haklai, Z., Mimouni, F. B., Gorfein, I., & Gordon, E.-S. (2005). Birth weight standards in the live-born population in Israel. Israel Medical Association Journal, 7(5), 311\u2013314.","journal-title":"Israel Medical Association Journal"},{"issue":"5 Pt 1","key":"1914_CR23","first-page":"1006","volume":"102","author":"HM Salihu","year":"2003","unstructured":"Salihu, H. M., Shumpert, M. N., Slay, M., Kirby, R. S., & Alexander, G. R. (2003). Childbearing beyond maternal age 50 and fetal outcomes in the United States. Obstetrics and Gynecology, 102(5 Pt 1), 1006\u20131014.","journal-title":"Obstetrics and Gynecology"},{"issue":"2","key":"1914_CR24","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1542\/peds.2008-2816","volume":"124","author":"CSH Aarnoudse-Moens","year":"2009","unstructured":"Aarnoudse-Moens, C. S. H., Weisglas-Kuperus, N., van Goudoever, J. B., & Oosterlaan, J. (2009). Meta-analysis of neurobehavioral outcomes in very preterm and\/or very low birth weight children. Pediatrics, 124(2), 717\u2013728.","journal-title":"Pediatrics"},{"issue":"8","key":"1914_CR25","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1093\/humrep\/der178","volume":"26","author":"C Gnoth","year":"2011","unstructured":"Gnoth, C., Maxrath, B., Skonieczny, T., Friol, K., Godehardt, E., & Tigges, J. (2011). Final ART success rates: a 10\u00a0years survey. Human Reproduction, 26(8), 2239\u20132246.","journal-title":"Human Reproduction"},{"key":"1914_CR26","unstructured":"Law of Oocyte Donation, 2010. Book of laws, 2242, Page 520. Available from: http:\/\/fs.knesset.gov.il\/\/18\/law\/18_lsr_300729.pdf . Accessed 21 Jan 2015 [in Hebrew]."},{"key":"1914_CR27","unstructured":"Israel Central Bureau of Statistics, Newborns in Single and Multiple Births, by Mother\u2019s Population Group, Religion and Age 2010 [Internet] 2013. Available from: http:\/\/www.cbs.gov.il\/reader\/shnaton\/shnatone_new.htm?CYear=2013&Vol=64&CSubject=30 . Accessed 15 Dec 2014"},{"key":"1914_CR28","first-page":"1","volume":"56","author":"American College of Obstetricians and Gynecologists","year":"2004","unstructured":"American College of Obstetricians and Gynecologists. (2004). Multiple gestation: complicated twin, triplet, and high-order multifetal pregnancy. ACOG Practice Bulletin, 56, 1\u201315.","journal-title":"ACOG Practice Bulletin"},{"key":"1914_CR29","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1093\/humrep\/dep238","volume":"24","author":"MJ Simchen","year":"2009","unstructured":"Simchen, M. J., Shulman, A., Wiser, A., Zilberberg, E., & Schiff, E. (2009). The aged uterus: Multifetal pregnancy outcome after ovum donation in older women. Human Reproduction, 24, 2500\u20132503.","journal-title":"Human Reproduction"},{"issue":"9606","key":"1914_CR30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","volume":"371","author":"RL Goldenberg","year":"2008","unstructured":"Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008). Epidemiology and causes of preterm birth. Lancet, 371(9606), 75\u201384.","journal-title":"Lancet"},{"issue":"5","key":"1914_CR31","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/humrep\/del522","volume":"22","author":"B Luke","year":"2007","unstructured":"Luke, B., & Brown, M. B. (2007). Elevated risks of pregnancy complications and adverse outcomes with increasing maternal age. Human Reproduction, 22(5), 1264\u20131272.","journal-title":"Human Reproduction"},{"key":"1914_CR32","doi-asserted-by":"crossref","unstructured":"Weaver, J., Statham, H., & Richards, M. (2001). High caesarean section rates among women over 30. High rates may be due to perceived potential for complications. BMJ (Clinical Research Ed.) 323(7307), 284\u2013285.","DOI":"10.1136\/bmj.323.7307.284"},{"issue":"3","key":"1914_CR33","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.ajog.2004.09.133","volume":"192","author":"H-C Lin","year":"2005","unstructured":"Lin, H.-C., & Xirasagar, S. (2005). Maternal age and the likelihood of a maternal request for cesarean delivery: A 5-year population-based study. American Journal of Obstetrics and Gynecology, 192(3), 848\u2013855.","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"1914_CR34","unstructured":"Israeli Society of Maternal Fetal Medicine. Obstetrics in Israel, Report for 2012. Annual conference of Israeli Society of Maternal Fetal Medicine. November 2012. Ramat-Gan, Israel."}],"container-title":["Maternal and Child Health Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10995-015-1914-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10995-015-1914-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10995-015-1914-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T01:42:02Z","timestamp":1559353322000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10995-015-1914-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,21]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["1914"],"URL":"https:\/\/doi.org\/10.1007\/s10995-015-1914-8","relation":{},"ISSN":["1092-7875","1573-6628"],"issn-type":[{"value":"1092-7875","type":"print"},{"value":"1573-6628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,21]]}}}