{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:44:36Z","timestamp":1767451476230},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T00:00:00Z","timestamp":1459209600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s11010-016-2684-3","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T05:44:16Z","timestamp":1459230256000},"page":"1-9","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["TMEM49-related apoptosis and metastasis in ovarian cancer and regulated cell death"],"prefix":"10.1007","volume":"416","author":[{"given":"Lili","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingfen","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,3,29]]},"reference":[{"issue":"5","key":"2684_CR1","doi-asserted-by":"crossref","first-page":"E359","DOI":"10.1002\/ijc.29210","volume":"136","author":"J Ferlay","year":"2015","unstructured":"Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136(5):E359\u2013E386","journal-title":"Int J Cancer"},{"issue":"5","key":"2684_CR2","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1158\/1078-0432.CCR-12-2243","volume":"19","author":"S Banerjee","year":"2013","unstructured":"Banerjee S, Kaye SB (2013) New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential. Clin Cancer Res 19(5):961\u2013968","journal-title":"Clin Cancer Res"},{"issue":"3","key":"2684_CR3","first-page":"567","volume":"16","author":"B Aunoble","year":"2000","unstructured":"Aunoble B, Sanches R, Didier E, Bignon Y (2000) Major oncogenes and tumor suppressor genes involved in epithelial ovarian cancer (review). Int J Oncol 16(3):567\u2013643","journal-title":"Int J Oncol"},{"issue":"19","key":"2684_CR4","first-page":"5382","volume":"60","author":"S Suzuki","year":"2000","unstructured":"Suzuki S, Moore DH, Ginzinger DG, Godfrey TE, Barclay J, Powell B, Pinkel D, Zaloudek C, Lu K, Mills G (2000) An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer. Cancer Res 60(19):5382\u20135385","journal-title":"Cancer Res"},{"issue":"1","key":"2684_CR5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000264680","volume":"10","author":"R Pardo","year":"2010","unstructured":"Pardo R, Lo R\u00e9 A, Archange C, Ropolo A, Papademetrio DL, Gonzalez CD, Alvarez EM, Iovanna JL, Vaccaro MI (2010) Gemcitabine induces the VMP1-mediated autophagy pathway to promote apoptotic death in human pancreatic cancer cells. Pancreatology 10(1):19\u201326","journal-title":"Pancreatology"},{"issue":"6","key":"2684_CR6","doi-asserted-by":"crossref","first-page":"933","DOI":"10.4161\/auto.24390","volume":"9","author":"MI Molejon","year":"2013","unstructured":"Molejon MI, Ropolo A, Vaccaro MI (2013) VMP1 is a new player in the regulation of the autophagy-specific phosphatidylinositol 3-kinase complex activation. Autophagy 9(6):933\u2013935","journal-title":"Autophagy"},{"issue":"2","key":"2684_CR7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1006\/bbrc.2001.6244","volume":"290","author":"NJ Dusetti","year":"2002","unstructured":"Dusetti NJ, Jiang Y, Vaccaro MI, Tomasini R, Samir AA, Calvo EL, Ropolo A, Fiedler F, Mallo GV, Dagorn J-C (2002) Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation. Biochem Biophys Res Commun 290(2):641\u2013649","journal-title":"Biochem Biophys Res Commun"},{"issue":"12","key":"2684_CR8","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1111\/cas.12025","volume":"103","author":"L Guo","year":"2012","unstructured":"Guo L, Yang LY, Fan C, Chen GD, Wu F (2012) Novel roles of Vmp1: inhibition metastasis and proliferation of hepatocellular carcinoma. Cancer Sci 103(12):2110\u20132119","journal-title":"Cancer Sci"},{"issue":"10","key":"2684_CR9","doi-asserted-by":"crossref","first-page":"8308","DOI":"10.1074\/jbc.M110.197301","volume":"286","author":"D Grasso","year":"2011","unstructured":"Grasso D, Ropolo A, Lo Re A, Boggio V, Molejon MI, Iovanna JL, Gonzalez CD, Urrutia R, Vaccaro MI (2011) Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. J Biol Chem 286(10):8308\u20138324. doi: 10.1074\/jbc.M110.197301","journal-title":"J Biol Chem"},{"issue":"51","key":"2684_CR10","doi-asserted-by":"crossref","first-page":"37124","DOI":"10.1074\/jbc.M706956200","volume":"282","author":"A Ropolo","year":"2007","unstructured":"Ropolo A, Grasso D, Pardo R, Sacchetti ML, Archange C, Re AL, Seux M, Nowak J, Gonzalez CD, Iovanna JL (2007) The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells. J Biol Chem 282(51):37124\u201337133","journal-title":"J Biol Chem"},{"issue":"9","key":"2684_CR11","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1038\/sj.onc.1210743","volume":"27","author":"M Sauermann","year":"2008","unstructured":"Sauermann M, Sahin \u00d6, S\u00fcltmann H, Hahne F, Blaszkiewicz S, Majety M, Zatloukal K, F\u00fczesi L, Poustka A, Wiemann S (2008) Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells. Oncogene 27(9):1320\u20131326","journal-title":"Oncogene"},{"issue":"1","key":"2684_CR12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1017\/S0009840X13002084","volume":"64","author":"R Siegel","year":"2014","unstructured":"Siegel R, Ma J, Zou Z, Jemal A (2014) Cancer statistics, 2014. CA 64(1):9\u201329","journal-title":"CA"},{"issue":"1\u20132","key":"2684_CR13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000178878","volume":"9","author":"D Grasso","year":"2009","unstructured":"Grasso D, Sacchetti ML, Bruno L, Lo Re A, Iovanna JL, Gonzalez CD, Vaccaro MI (2009) Autophagy and VMP1 expression are early cellular events in experimental diabetes. Pancreatology 9(1\u20132):81\u201388. doi: 10.1159\/000178878","journal-title":"Pancreatology"},{"issue":"3","key":"2684_CR14","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.bbrc.2013.12.090","volume":"443","author":"Q Qian","year":"2014","unstructured":"Qian Q, Zhou H, Chen Y, Shen C, He S, Zhao H, Wang L, Wan D, Gu W (2014) VMP1 related autophagy and apoptosis in colorectal cancer cells: vMP1 regulates cell death. Biochem Biophys Res Commun 443(3):1041\u20131047","journal-title":"Biochem Biophys Res Commun"},{"issue":"23","key":"2684_CR15","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.1093\/bioinformatics\/btm369","volume":"23","author":"A Subramanian","year":"2007","unstructured":"Subramanian A, Kuehn H, Gould J, Tamayo P, Mesirov JP (2007) GSEA-P: a desktop application for gene set enrichment analysis. Bioinformatics 23(23):3251\u20133253","journal-title":"Bioinformatics"},{"issue":"2","key":"2684_CR16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/sj.cdd.4400476","volume":"6","author":"AG Porter","year":"1999","unstructured":"Porter AG, J\u00e4nicke RU (1999) Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6(2):99\u2013104","journal-title":"Cell Death Differ"},{"issue":"6951","key":"2684_CR17","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nature01825","volume":"424","author":"NN Danial","year":"2003","unstructured":"Danial NN, Gramm CF, Scorrano L, Zhang C-Y, Krauss S, Ranger AM, Datta SR, Greenberg ME, Licklider LJ, Lowell BB (2003) BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424(6951):952\u2013956","journal-title":"Nature"},{"issue":"4","key":"2684_CR18","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0092-8674(93)90509-O","volume":"74","author":"ZN Oltval","year":"1993","unstructured":"Oltval ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74(4):609\u2013619","journal-title":"Cell"},{"issue":"1","key":"2684_CR19","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1742-4658.2010.07919.x","volume":"278","author":"C Gialeli","year":"2011","unstructured":"Gialeli C, Theocharis AD, Karamanos NK (2011) Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J 278(1):16\u201327","journal-title":"FEBS J"},{"issue":"1","key":"2684_CR20","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/biof.67","volume":"36","author":"M Subramaniam","year":"2010","unstructured":"Subramaniam M, Hawse JR, Rajamannan NM, Ingle JN, Spelsberg TC (2010) Functional role of KLF10 in multiple disease processes. Biofactors 36(1):8\u201318","journal-title":"Biofactors"},{"issue":"20","key":"2684_CR21","first-page":"5930","volume":"62","author":"CJ Scotton","year":"2002","unstructured":"Scotton CJ, Wilson JL, Scott K, Stamp G, Wilbanks GD, Fricker S, Bridger G, Balkwill FR (2002) Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res 62(20):5930\u20135938","journal-title":"Cancer Res"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-016-2684-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11010-016-2684-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-016-2684-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T09:49:14Z","timestamp":1718444954000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11010-016-2684-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,29]]},"references-count":21,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["2684"],"URL":"https:\/\/doi.org\/10.1007\/s11010-016-2684-3","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,29]]}}}