{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:25:29Z","timestamp":1791894329264,"version":"4.3.4"},"reference-count":89,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T00:00:00Z","timestamp":1623628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T00:00:00Z","timestamp":1623628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100007351","name":"Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires","doi-asserted-by":"crossref","award":["UBACYT M032"],"award-info":[{"award-number":["UBACYT M032"]}],"id":[{"id":"10.13039\/501100007351","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 01071"],"award-info":[{"award-number":["PICT 01071"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s11010-021-04192-4","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T12:03:01Z","timestamp":1623672181000},"page":"3857-3867","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Myocardial remote ischemic preconditioning: from cell biology to clinical application"],"prefix":"10.1007","volume":"476","author":[{"given":"Mart\u00edn","family":"Donato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana P.","family":"Bin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"D\u00b4Annunzio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6491-9209","authenticated-orcid":false,"given":"Ricardo J.","family":"Gelpi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"key":"4192_CR1","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1161\/01.cir.87.3.893","volume":"87","author":"K Przyklenk","year":"1993","unstructured":"Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P (1993) Regional ischemic \u2018preconditioning\u2019 protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 87:893\u2013899. https:\/\/doi.org\/10.1161\/01.cir.87.3.893","journal-title":"Circulation"},{"key":"4192_CR2","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1161\/01.cir.74.5.1124","volume":"74","author":"CE Murry","year":"1986","unstructured":"Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124\u20131136. https:\/\/doi.org\/10.1161\/01.cir.74.5.1124","journal-title":"Circulation"},{"key":"4192_CR3","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1161\/01.cir.0000043806.51912.9b","volume":"106","author":"RK Kharbanda","year":"2002","unstructured":"Kharbanda RK, Mortensen UM, White PA, Kristiansen SB, Schmidt MR, Hoschtitzky JA, Vogel M, Sorensen K, Redington AN, MacAllister R (2002) Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 106:2881\u20132883. https:\/\/doi.org\/10.1161\/01.cir.0000043806.51912.9b","journal-title":"Circulation"},{"key":"4192_CR4","doi-asserted-by":"publisher","first-page":"27","DOI":"10.3389\/fphys.2012.00027","volume":"3","author":"SY Lim","year":"2012","unstructured":"Lim SY, Hausenloy DJ (2012) Remote ischemic conditioning: from bench to bedside. Front Physiol 3:27. https:\/\/doi.org\/10.3389\/fphys.2012.00027","journal-title":"Front Physiol"},{"key":"4192_CR5","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1097\/01.ta.0000240440.85673.fc","volume":"63","author":"M Schoen","year":"2007","unstructured":"Schoen M, Rotter R, Gierer P, Gradl G, Strauss U, Jonas L, Mittlmeier T, Vollmar B (2007) Ischemic preconditioning prevents skeletal muscle tissue injury, but not nerve lesion upon tourniquet-induced ischemia. J Trauma 63:788\u2013797. https:\/\/doi.org\/10.1097\/01.ta.0000240440.85673.fc","journal-title":"J Trauma"},{"issue":"2","key":"4192_CR6","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1097\/ACO.0000000000000161","volume":"28","author":"A Zarbock","year":"2015","unstructured":"Zarbock A, Van Aken H, Schmidt C (2015) Remote ischemic preconditioning and outcome: shall we all have an intermittent tourniquet? Curr Opin Anaesthesiol 28(2):165\u2013171. https:\/\/doi.org\/10.1097\/ACO.0000000000000161","journal-title":"Curr Opin Anaesthesiol"},{"issue":"2","key":"4192_CR7","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.advms.2016.11.006","volume":"62","author":"K Stokfisz","year":"2017","unstructured":"Stokfisz K, Ledakowicz-Polak A, Zagorski M, Zielinska M (2017) Ischaemic preconditioning\u2013Current knowledge and potential future applications after 30 years of experience. Adv Med Sci 62(2):307\u2013316. https:\/\/doi.org\/10.1016\/j.advms.2016.11.006","journal-title":"Adv Med Sci"},{"issue":"3","key":"4192_CR8","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s10557-010-6237-9","volume":"24","author":"DJ Hausenloy","year":"2010","unstructured":"Hausenloy DJ, Yellon DM (2010) The second window of preconditioning (SWOP) where are we now? Cardiovasc Drugs Ther 24(3):235\u2013254. https:\/\/doi.org\/10.1007\/s10557-010-6237-9","journal-title":"Cardiovasc Drugs Ther"},{"key":"4192_CR9","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1093\/bja\/aem273","volume":"99","author":"SR Walsh","year":"2007","unstructured":"Walsh SR, Tang T, Sadat U, Dutka DP, Gaunt ME (2007) Cardioprotection by remote ischaemic preconditioning. Br J Anaesth 99:611\u2013616. https:\/\/doi.org\/10.1093\/bja\/aem273","journal-title":"Br J Anaesth"},{"key":"4192_CR10","doi-asserted-by":"publisher","first-page":"H1883","DOI":"10.1152\/ajpheart.00617.2006","volume":"292","author":"MR Schmidt","year":"2007","unstructured":"Schmidt MR, Smerup M, Konstantinov IE, Shimizu M, Li J, Cheung M, White PA, Kristiansen SB, Sorensen K, Dzavik V, Redington AN, Kharbanda RK (2007) Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning. Am J Physiol Heart Circ Physiol 292:H1883-1890. https:\/\/doi.org\/10.1152\/ajpheart.00617.2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"12","key":"4192_CR11","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1111\/j.1540-8167.2012.02397.x","volume":"23","author":"J Dow","year":"2012","unstructured":"Dow J, Bhandari A, Simkhovich BZ, Hale SL, Kloner RA (2012) The effect of acute versus delayed remote ischemic preconditioning on reperfusion induced ventricular arrhythmias. J Cardiovasc Electrophysiol 23(12):1374\u20131383. https:\/\/doi.org\/10.1111\/j.1540-8167.2012.02397.x","journal-title":"J Cardiovasc Electrophysiol"},{"key":"4192_CR12","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1016\/j.jtcvs.2005.03.050","volume":"130","author":"IE Konstantinov","year":"2005","unstructured":"Konstantinov IE, Arab S, Li J, Coles JG, Boscarino C, Mori A, Cukerman E, Dawood F, Cheung M, Shimizu M, Liu P, Redington AN (2005) The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium. J Thorac Cardiovasc Surg 130:1326\u20131332. https:\/\/doi.org\/10.1016\/j.jtcvs.2005.03.050","journal-title":"J Thorac Cardiovasc Surg"},{"key":"4192_CR13","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1152\/physiolgenomics.00046.2004","volume":"19","author":"IE Konstantinov","year":"2004","unstructured":"Konstantinov IE, Arab S, Kharbanda RK, Cheung M, Cherepanov V, Downey GP, Liu P, Cukerman E, Coles JG, Redington AN (2004) The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans. Physiol Genom 19:143\u2013150. https:\/\/doi.org\/10.1152\/physiolgenomics.00046.2004","journal-title":"Physiol Genom"},{"key":"4192_CR14","doi-asserted-by":"publisher","first-page":"H1165","DOI":"10.1152\/ajpheart.00899.2004","volume":"288","author":"DA Liem","year":"2005","unstructured":"Liem DA, te Lintel HM, Manintveld OC, Boomsma F, Verdouw PD, Duncker DJ (2005) Myocardium tolerant to an adenosine-dependent ischemic preconditioning stimulus can still be protected by stimuli that employ alternative signaling pathways. Am J Physiol Heart Circ Physiol 288:H1165-1172. https:\/\/doi.org\/10.1152\/ajpheart.00899.2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"4192_CR15","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1161\/01.cir.94.9.2193","volume":"94","author":"BC Gho","year":"1996","unstructured":"Gho BC, Schoemaker RG, van den Doel MA, Duncker DJ, Verdouw PD (1996) Myocardial protection by brief ischemia in noncardiac tissue. Circulation 94:2193\u20132200. https:\/\/doi.org\/10.1161\/01.cir.94.9.2193","journal-title":"Circulation"},{"issue":"2","key":"4192_CR16","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1113\/expphysiol.2012.066217","volume":"98","author":"M Donato","year":"2013","unstructured":"Donato M, Buchholz B, Rodr\u00edguez M, P\u00e9rez V, Inserte J, Garc\u00eda-Dorado D, Gelpi RJ (2013) Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning. Exp Physiol 98(2):425\u2013434. https:\/\/doi.org\/10.1113\/expphysiol.2012.066217","journal-title":"Exp Physiol"},{"key":"4192_CR17","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1097\/01.tp.0000159137.76400.5d","volume":"79","author":"IE Konstantinov","year":"2005","unstructured":"Konstantinov IE, Li J, Cheung MM, Shimizu M, Stokoe J, Kharbanda RK, Redington AN (2005) Remote ischemic preconditioning of the recipient reduces myocardial ischemia reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism. Transplantation 79:1691\u20131695. https:\/\/doi.org\/10.1097\/01.tp.0000159137.76400.5d","journal-title":"Transplantation"},{"key":"4192_CR18","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1006\/jmcc.2001.1436","volume":"33","author":"EW Dickson","year":"2001","unstructured":"Dickson EW, Blehar DJ, Carraway RE, Heard SO, Steinberg G, Przyklenk K (2001) Naloxone blocks transferred preconditioning in isolated rabbit hearts. J Mol Cell Cardiol 33:1751\u20131756. https:\/\/doi.org\/10.1006\/jmcc.2001.1436","journal-title":"J Mol Cell Cardiol"},{"key":"4192_CR19","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1042\/CS20080523","volume":"117","author":"M Shimizu","year":"2009","unstructured":"Shimizu M, Tropak M, Diaz RJ, Suto F, Surendra H, Kuzmin E, Li J, Gross G, Wilson GJ, Callahan J, Redington AN (2009) Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection. Clin Sci (Lond) 117:191\u2013200. https:\/\/doi.org\/10.1042\/CS20080523","journal-title":"Clin Sci (Lond)"},{"key":"4192_CR20","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00395-012-0285-1","volume":"107","author":"RV Jensen","year":"2012","unstructured":"Jensen RV, Stottrup NB, Kristiansen SB, B\u00f8tker HE (2012) Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients. Basic Res Cardiol 107:285. https:\/\/doi.org\/10.1007\/s00395-012-0285-1","journal-title":"Basic Res Cardiol"},{"issue":"1","key":"4192_CR21","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1093\/cvr\/cvw242","volume":"113","author":"J Jos\u00e9 Alburquerque-B\u00e9jar","year":"2017","unstructured":"Jos\u00e9 Alburquerque-B\u00e9jar J, Barba I, Valls-Lacalle L, Ruiz-Meana M, Pecoraro M, Rodr\u00edguez-Sinovas A, Garc\u00eda-Dorado D (2017) Remote ischemic conditioning provides humoural cross-species cardioprotection through glycine receptor activation. Cardiovasc Res 113(1):52\u201360. https:\/\/doi.org\/10.1093\/cvr\/cvw242","journal-title":"Cardiovasc Res"},{"issue":"1","key":"4192_CR22","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1007\/s00395-012-0314-0","volume":"108","author":"M Albrecht","year":"2013","unstructured":"Albrecht M, Zitta K, Bein B, Wennemuth G, Broch O, Renner J, Schuett T, Lauer F, Maahs D, Hummitzsch L, Cremer J, Zacharowski K, Meybohm P (2013) Remote ischemic preconditioning regulates HIF-1\u03b1 levels, apoptosis and inflammation in heart tissue of cardiosurgical patients: a pilot experimental study. Basic Res Cardiol 108(1):314. https:\/\/doi.org\/10.1007\/s00395-012-0314-0","journal-title":"Basic Res Cardiol"},{"key":"4192_CR23","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.bbrc.2015.06.054","volume":"463","author":"Y Gao","year":"2015","unstructured":"Gao Y, Song J, Chen H, Cao C, Lee C (2015) TRPV1 activation is involved in the cardioprotection of remote limb ischemic postconditioning in ischemia-reperfusion injury rats. Biochem Biophys Res Commun 463:1034\u20131039. https:\/\/doi.org\/10.1016\/j.bbrc.2015.06.054","journal-title":"Biochem Biophys Res Commun"},{"key":"4192_CR24","doi-asserted-by":"publisher","first-page":"H29","DOI":"10.1152\/ajpheart.01031.2001","volume":"283","author":"DA Liem","year":"2002","unstructured":"Liem DA, Verdouw PD, Ploeg H, Kazim S, Duncker D (2002) Sites of action of adenosine in interorgan preconditioning of the heart. Am J Physiol Heart Circ Physiol 283:H29\u2013H37. https:\/\/doi.org\/10.1152\/ajpheart.01031.2001","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"1\u20132","key":"4192_CR25","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.jacbts.2016.01.007","volume":"1","author":"HA Hildebrandt","year":"2016","unstructured":"Hildebrandt HA, Kreienkamp V, Gent S, Kahlert P, Heusch G, Kleinbongard P (2016) Kinetics and signal activation properties of circulating factor(s) from healthy volunteers undergoing remote ischemic pre-conditioning. JACC Basic Transl Sci 1(1\u20132):3\u201313. https:\/\/doi.org\/10.1016\/j.jacbts.2016.01.007","journal-title":"JACC Basic Transl Sci"},{"issue":"3","key":"4192_CR26","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1093\/cvr\/cvw216","volume":"112","author":"MV Basalay","year":"2016","unstructured":"Basalay MV, Mastitskaya S, Mrochek A, Ackland GL, Del Arroyo AG, Sanchez J, Sjoquist PO, Pernow J, Gourine AV, Gourine A (2016) Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning. Cardiovasc Res 112(3):669\u2013676. https:\/\/doi.org\/10.1093\/cvr\/cvw216","journal-title":"Cardiovasc Res"},{"issue":"10","key":"4192_CR27","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1161\/CIRCRESAHA.114.303822","volume":"114","author":"T Rassaf","year":"2014","unstructured":"Rassaf T, Totzeck M, Hendgen-Cotta UB, Shiva S, Heusch G, Kelm M (2014) Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning. Circ Res 114(10):1601\u20131610. https:\/\/doi.org\/10.1161\/CIRCRESAHA.114.303822","journal-title":"Circ Res"},{"key":"4192_CR28","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1161\/CIRCRESAHA.116.305348","volume":"116","author":"G Heusch","year":"2015","unstructured":"Heusch G (2015) Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning. Circ Res 116:674\u2013699. https:\/\/doi.org\/10.1161\/CIRCRESAHA.116.305348","journal-title":"Circ Res"},{"issue":"5","key":"4192_CR29","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1042\/CS20080523","volume":"117","author":"M Shimizu","year":"2009","unstructured":"Shimizu M, Tropak M, Diaz RJ, Suto F, Surendra H, Kuzmin E, Li J, Gross G, Wilson GJ, Callahan J, Redington AN (2009) Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection. Clin Sci (Lond) 117(5):191\u2013200. https:\/\/doi.org\/10.1042\/CS20080523","journal-title":"Clin Sci (Lond)"},{"issue":"2","key":"4192_CR30","doi-asserted-by":"publisher","first-page":"e32296","DOI":"10.1371\/journal.pone.0032296","volume":"7","author":"KE Wever","year":"2012","unstructured":"Wever KE, Menting TP, Maroeska Rovers J, van der Vliet A, Rongen GA, Masereeuw R, Ritskes-Hoitinga M, Hooijmans CR, Warl\u00e9 M (2012) Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis. PLoS ONE 7(2):e32296. https:\/\/doi.org\/10.1371\/journal.pone.0032296","journal-title":"PLoS ONE"},{"issue":"2","key":"4192_CR31","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s00395-016-0529-6","volume":"111","author":"J Johnsen","year":"2016","unstructured":"Johnsen J, Pryds K, Salman R, L\u00f8fgren B, Kristiansen SB, B\u00f8tker HE (2016) The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection. Basic Res Cardiol 111(2):10. https:\/\/doi.org\/10.1007\/s00395-016-0529-6","journal-title":"Basic Res Cardiol"},{"issue":"4","key":"4192_CR32","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s00395-018-0684-z","volume":"113","author":"MV Basalay","year":"2018","unstructured":"Basalay MV, Davidson SM, Gourine AV, Yellon DM (2018) Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects. Basic Res Cardiol 113(4):25. https:\/\/doi.org\/10.1007\/s00395-018-0684-z","journal-title":"Basic Res Cardiol"},{"issue":"6","key":"4192_CR33","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1113\/EP085535","volume":"101","author":"M Donato","year":"2016","unstructured":"Donato M, Goyeneche MA, Garces M, Marchini T, P\u00e9rez V, Del Mauro J, H\u00f6cht C, Rodr\u00edguez M, Evelson P, Gelpi RJ (2016) Myocardial triggers involved in activation of remote ischaemic preconditioning. Exp Physiol 101(6):708\u2013716. https:\/\/doi.org\/10.1113\/EP085535","journal-title":"Exp Physiol"},{"issue":"4","key":"4192_CR34","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1093\/cvr\/cvs212","volume":"95","author":"S Mastitskaya","year":"2012","unstructured":"Mastitskaya S, Marina N, Gourine A, Gilbey MP, Spyer KM, Teschemacher AG, Kasparov S, Trapp S, Ackland GL, Gourine AV (2012) Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones. Cardiovasc Res 95(4):487\u2013494. https:\/\/doi.org\/10.1093\/cvr\/cvs212","journal-title":"Cardiovasc Res"},{"issue":"7","key":"4192_CR35","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1093\/cvr\/cvz053","volume":"115","author":"DJ Hausenloy","year":"2019","unstructured":"Hausenloy DJ, B\u00f8tker HE, Ferdinandy P, Heusch G, Ng GA, Redington A, Garcia-Dorado D (2019) Cardiac innervation in acute myocardial ischaemia\/reperfusion injury and cardioprotection. Cardiovasc Res 115(7):1167\u20131177. https:\/\/doi.org\/10.1093\/cvr\/cvz053","journal-title":"Cardiovasc Res"},{"issue":"6","key":"4192_CR36","doi-asserted-by":"publisher","first-page":"508","DOI":"10.4330\/wjc.v9.i6.508","volume":"9","author":"JG Kingma","year":"2017","unstructured":"Kingma JG, Simard D, Rouleau JR (2017) Influence of cardiac nerve status on cardiovascular regulation and cardioprotection. World J Cardiol 9(6):508\u2013520. https:\/\/doi.org\/10.4330\/wjc.v9.i6.508","journal-title":"World J Cardiol"},{"issue":"3","key":"4192_CR37","doi-asserted-by":"publisher","first-page":"e0121972","DOI":"10.1371\/journal.pone.0121972","volume":"10","author":"J Jia","year":"2015","unstructured":"Jia J, Li J, Jiang L, Zhang J, Chen S, Wang L, Zhou Y, Xie H, Zhou L, Zheng S (2015) Protective effect of remote limb ischemic perconditioning on the liver grafts of rats with a novel model. PLoS ONE 10(3):e0121972. https:\/\/doi.org\/10.1371\/journal.pone.0121972","journal-title":"PLoS ONE"},{"key":"4192_CR38","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.ejcts.2004.06.015","volume":"26","author":"G Li","year":"2004","unstructured":"Li G, Labruto F, Sirsjo A, Chen F, Vaage J, Valen G (2004) Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase. Eur J Cardiothorac Surg 26:968\u2013973. https:\/\/doi.org\/10.1016\/j.ejcts.2004.06.015","journal-title":"Eur J Cardiothorac Surg"},{"key":"4192_CR39","doi-asserted-by":"publisher","first-page":"31437","DOI":"10.1074\/jbc.273.47.31437","volume":"273","author":"YM Kim","year":"1998","unstructured":"Kim YM, Kim TH, Seol DW, Talanian RV, Billiar TR (1998) Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release. J Biol Chem 273:31437\u201331441. https:\/\/doi.org\/10.1074\/jbc.273.47.31437","journal-title":"J Biol Chem"},{"key":"4192_CR40","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.4049\/jimmunol.161.8.4122","volume":"161","author":"YM Kim","year":"1998","unstructured":"Kim YM, Talanian RV, Li J, Billiar T (1998) Nitric oxide prevents IL-1beta and IFN-gamma-inducing factor (IL-18) release from macrophages by inhibiting caspase-1 (IL-1beta-converting enzyme). J Immunol 161:4122\u20134128","journal-title":"J Immunol"},{"key":"4192_CR41","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.ijcard.2014.10.144","volume":"178","author":"T Yamaguchi","year":"2015","unstructured":"Yamaguchi T, Izumi Y, Nakamura Y, Yamazaki T, Shiota M, Sano S, Tanaka M, Osada-Oka M, Shimada K, Miura K, Yoshiyama M, Iwao H (2015) Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after myocardial infarction. Int J Cardiol 178:239\u2013246. https:\/\/doi.org\/10.1016\/j.ijcard.2014.10.144","journal-title":"Int J Cardiol"},{"issue":"10","key":"4192_CR42","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1161\/CIRCRESAHA.110.236190","volume":"108","author":"M Wei","year":"2011","unstructured":"Wei M, Xin P, Li S, Tao J, Li Y, Li J, Liu M, Li J, Zhu W, Redington AN (2011) Repeated remote ischemic postconditioning protects against adverse left ventricular remodeling and improves survival in a rat model of myocardial infarction. Circ Res 108(10):1220\u20131225. https:\/\/doi.org\/10.1161\/CIRCRESAHA.110.236190","journal-title":"Circ Res"},{"key":"4192_CR43","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.ijcard.2019.03.003","volume":"285","author":"PM Pilz","year":"2019","unstructured":"Pilz PM, Hamza O, Gidl\u00f6f O, Gon\u00e7alves IF, Tretter EV, Trojanek S, Abraham D, Heber S, Haller PM, Podesser BK, Kiss A (2019) Remote ischemic perconditioning attenuates adverse cardiac remodeling and preserves left ventricular function in a rat model of reperfused myocardial infarction. Int J Cardiol 285:72\u201379. https:\/\/doi.org\/10.1016\/j.ijcard.2019.03.003","journal-title":"Int J Cardiol"},{"key":"4192_CR44","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1093\/cvr\/cvy014","volume":"114","author":"H Chen","year":"2018","unstructured":"Chen H, Jing X-Y, Shen Y-J, Wang T-L, Ou C, Lu S-F, Cai Y, Li Q, Chen X, Ding Y-J, Yu X-C, Zhu B-M (2018) Stat5-dependent cardioprotection in late remote ischaemia preconditioning. Cardiovasc Res 114:679\u2013689. https:\/\/doi.org\/10.1093\/cvr\/cvy014","journal-title":"Cardiovasc Res"},{"key":"4192_CR45","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1093\/cvr\/cvy014","volume":"110","author":"G Heusch","year":"2012","unstructured":"Heusch G, Musiolik J, Kottenberg E, Peters J, Jakob H, Thielmann M (2012) STAT5 activation and cardioprotection by remote ischemic preconditioning in humans: short communication. Circ Res 110:111\u2013115. https:\/\/doi.org\/10.1093\/cvr\/cvy014","journal-title":"Circ Res"},{"key":"4192_CR46","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00395-019-0763-9","volume":"115","author":"M Billah","year":"2019","unstructured":"Billah M, Ridiandries A, Rayner BS, Allahwala UK, Dona A, Khachigian LM, Bhindi R (2019) Egr-1 functions as a master switch regulator of remote ischemic preconditioning-induced cardioprotection. Basic Res Cardiol 115:3\u20133. https:\/\/doi.org\/10.1007\/s00395-019-0763-9","journal-title":"Basic Res Cardiol"},{"key":"4192_CR47","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1186\/s12974-018-1190-9","volume":"15","author":"C Chen","year":"2018","unstructured":"Chen C, Jiang W, Liu Z, Li F, Yang J, Zhao Y, Ran Y, Meng Y, Ji X, Geng X, Du H, Hu X (2018) Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke. J Neuroinflamm 15:167. https:\/\/doi.org\/10.1186\/s12974-018-1190-9","journal-title":"J Neuroinflamm"},{"key":"4192_CR48","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1007\/s00395-021-00852-0","volume":"116","author":"L Pearce","year":"2021","unstructured":"Pearce L, Davidson SM, Yellon DM (2021) Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response. Basic Res Cardiol 116:12. https:\/\/doi.org\/10.1007\/s00395-021-00852-0","journal-title":"Basic Res Cardiol"},{"key":"4192_CR49","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.surg.2011.05.017","volume":"150","author":"MC Manukyan","year":"2011","unstructured":"Manukyan MC, Alvernaz CH, Poynter JA, Wang Y, Brewster BD, Weil BR, Abarbanell AM, Herrmann JL, Crowe BJ, Keck AC, Meldrum DR (2011) Interleukin-10 protects the ischemic heart from reperfusion injury via the STAT3 pathway. Surgery 150:231\u2013239. https:\/\/doi.org\/10.1016\/j.surg.2011.05.017","journal-title":"Surgery"},{"key":"4192_CR50","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1093\/cvr\/cvn114","volume":"79","author":"DJ Hausenloy","year":"2008","unstructured":"Hausenloy DJ, Yellon DM (2008) Remote ischaemic preconditioning: underlying mechanisms and clinical application. Cardiovasc Res 79:377\u2013386. https:\/\/doi.org\/10.1093\/cvr\/cvn114","journal-title":"Cardiovasc Res"},{"key":"4192_CR51","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1038\/nrneph.2013.226","volume":"9","author":"LE Crowley","year":"2013","unstructured":"Crowley LE, McIntyre CW (2013) Remote ischaemic conditioning\u2014therapeutic opportunities in renal medicine. Nat Rev Nephrol 9:739\u2013746. https:\/\/doi.org\/10.1038\/nrneph.2013.226","journal-title":"Nat Rev Nephrol"},{"issue":"2","key":"4192_CR52","doi-asserted-by":"publisher","first-page":"e32296","DOI":"10.1371\/journal.pone.0032296","volume":"7","author":"KE Wever","year":"2012","unstructured":"Wever KE, Menting TP, Rovers M, van der Vliet JA, Rongen GA, Masereeuw R, Ritskes-Hoitinga M, Hooijmans CR, Warl\u00e9 M (2012) Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis. PLoS ONE 7(2):e32296. https:\/\/doi.org\/10.1371\/journal.pone.0032296","journal-title":"PLoS ONE"},{"key":"4192_CR53","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1016\/j.resuscitation.2011.02.010","volume":"82","author":"WC Jan","year":"2011","unstructured":"Jan WC, Chen CH, Tsai PS, Huang CJ (2011) Limb ischemic preconditioning mitigates lung injury induced by haemorrhagic shock\/resuscitation in rats. Resuscitation 82:760\u2013766. https:\/\/doi.org\/10.1016\/j.resuscitation.2011.02.010","journal-title":"Resuscitation"},{"key":"4192_CR54","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1053\/jhep.2001.20529","volume":"33","author":"C Peralta","year":"2001","unstructured":"Peralta C, Fernandez L, Panes J, Prats N, Sans M, Pique JM, Gelpi E, Rosello-Catafau J (2001) Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor-induced P-selectin up-regulation in the rat. Hepatology 33:100\u2013113. https:\/\/doi.org\/10.1053\/jhep.2001.20529","journal-title":"Hepatology"},{"key":"4192_CR55","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/j.1399-6576.2006.00938.x","volume":"50","author":"C Olguner","year":"2006","unstructured":"Olguner C, Koca U, Kar A, Karci A, Islekel H, Canyilmaz M, Mavioglu O, Kizildag S, Unlu G, Elar Z (2006) Ischemic preconditioning attenuates the lipid peroxidation and remote lung injury in the rat model of unilateral lower limb ischemia reperfusion. Acta anaesthesiol Scand 50:150\u2013155. https:\/\/doi.org\/10.1111\/j.1399-6576.2006.00938.x","journal-title":"Acta anaesthesiol Scand"},{"key":"4192_CR56","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1007\/BF03021061","volume":"50","author":"Z Xia","year":"2003","unstructured":"Xia Z, Herijgers P, Nishida T, Ozaki S, Wouters P, Flameng W (2003) Remote preconditioning lessens the deterioration of pulmonary function after repeated coronary artery occlusion and reperfusion in sheep. Can J Anaesth 50:481\u2013488. https:\/\/doi.org\/10.1007\/BF03021061","journal-title":"Can J Anaesth"},{"key":"4192_CR57","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1097\/01.tp.0000203555.14546.63","volume":"81","author":"IR Lai","year":"2006","unstructured":"Lai IR, Chang KJ, Chen CF, Tsai HW (2006) Transient limb ischemia induces remote preconditioning in liver among rats: the protective role of heme oxygenase-1. Transplantation 81:1311\u20131317. https:\/\/doi.org\/10.1097\/01.tp.0000203555.14546.63","journal-title":"Transplantation"},{"key":"4192_CR58","doi-asserted-by":"publisher","first-page":"2708","DOI":"10.1016\/j.transproceed.2006.07.044","volume":"38","author":"BI Gustafsson","year":"2006","unstructured":"Gustafsson BI, Friman S, Wallin M, Heiman J, Delbro DS (2006) Effect of remote preconditioning on mild or severe ischemia-reperfusion injury to rat liver. Transplant Proc 38:2708\u20132709. https:\/\/doi.org\/10.1016\/j.transproceed.2006.07.044","journal-title":"Transplant Proc"},{"key":"4192_CR59","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1097\/SLA.0b013e3181bfda8c","volume":"251","author":"F Wang","year":"2010","unstructured":"Wang F, Birch SE, He R, Tawadros P, Szaszi K, Kapus A, Rotstein OD (2010) Remote ischemic preconditioning by hindlimb occlusion prevents liver ischemic\/reperfusion injury: the role of high mobility group-box 1. Ann Surg 251:292\u2013299. https:\/\/doi.org\/10.1097\/SLA.0b013e3181bfda8c","journal-title":"Ann Surg"},{"key":"4192_CR60","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1002\/bjs.5331","volume":"93","author":"S Kanoria","year":"2006","unstructured":"Kanoria S, Jalan R, Davies NA, Seifalian AM, Williams R, Davidson BR (2006) Remote ischaemic preconditioning of the hind limb reduces experimental liver warm ischaemia-reperfusion injury. Br J Surg 93:762\u2013768. https:\/\/doi.org\/10.1002\/bjs.5331","journal-title":"Br J Surg"},{"issue":"18","key":"4192_CR61","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1212\/WNL.0b013e318271f76a","volume":"79","author":"R Meng","year":"2012","unstructured":"Meng R, Asmaro K, Meng L, Liu Y, Ma C, Xi C, Li G, Ren C, Luo Y, Ling F, Jia J, Hua Y, Wang X, Ding Y, Lo EH, Ji X (2012) Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Neurology 79(18):1853\u20131861. https:\/\/doi.org\/10.1212\/WNL.0b013e318271f76a","journal-title":"Neurology"},{"key":"4192_CR62","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1177\/1538574410369709","volume":"44","author":"SR Walsh","year":"2010","unstructured":"Walsh SR, Nouraei SA, Tang TY, Sadat U, Carpenter RH, Gaunt ME (2010) Remote ischemic preconditioning for cerebral and cardiac protection during carotid endarterectomy: results from a pilot randomized clinical trial. Vascul Endovasc Surg 44:434\u2013439. https:\/\/doi.org\/10.1177\/1538574410369709","journal-title":"Vascul Endovasc Surg"},{"issue":"1","key":"4192_CR63","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1186\/s12974-018-1190-9","volume":"15","author":"C Chen","year":"2018","unstructured":"Chen C, Jiang W, Liu Z, Li F, Yang J, Zhao Y, Ran Y, Meng Y, Ji X, Geng X, Du H, Hu X (2018) Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke. J Neuroinflamm 15(1):167. https:\/\/doi.org\/10.1186\/s12974-018-1190-9","journal-title":"J Neuroinflamm"},{"key":"4192_CR64","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.1016\/j.jacc.2006.01.066","volume":"47","author":"MM Cheung","year":"2006","unstructured":"Cheung MM, Kharbanda RK, Konstantinov IE, Shimizu M, Frndova H, Li J, Holtby HM, Cox PN, Smallhorn JF, Van Arsdell GS, Redington AN (2006) Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol 47:2277\u20132282. https:\/\/doi.org\/10.1016\/j.jacc.2006.01.066","journal-title":"J Am Coll Cardiol"},{"key":"4192_CR65","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S0140-6736(07)61296-3","volume":"370","author":"DJ Hausenloy","year":"2007","unstructured":"Hausenloy DJ, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM (2007) Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet 370:575\u2013579. https:\/\/doi.org\/10.1016\/S0140-6736(07)61296-3","journal-title":"Lancet"},{"issue":"25","key":"4192_CR66","doi-asserted-by":"publisher","first-page":"4544","DOI":"10.2174\/1381612811319250004","volume":"19","author":"DJ Hausenloy","year":"2013","unstructured":"Hausenloy DJ (2013) Cardioprotection techniques: preconditioning, postconditioning and remote conditioning (basic science). Curr Pharm Des 19(25):4544\u20134563. https:\/\/doi.org\/10.2174\/1381612811319250004","journal-title":"Curr Pharm Des"},{"issue":"1","key":"4192_CR67","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s00395-014-0453-6","volume":"110","author":"JM Pickard","year":"2015","unstructured":"Pickard JM, B\u00f8tker HE, Crimi G, Davidson B, Davidson SM, Dutka D, Ferdinandy P, Ganske R, Garcia-Dorado D, Giricz Z, Gourine AV, Heusch G, Kharbanda R, Kleinbongard P, MacAllister R, McIntyre C, Meybohm P, Prunier F, Redington A, Robertson NJ, Suleiman MS, Vanezis A, Walsh S, Yellon DM, Hausenloy DJ (2015) Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute workshop. Basic Res Cardiol 110(1):453. https:\/\/doi.org\/10.1007\/s00395-014-0453-6","journal-title":"Basic Res Cardiol"},{"issue":"6","key":"4192_CR68","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1093\/cvr\/cvx049","volume":"113","author":"DJ Hausenloy","year":"2017","unstructured":"Hausenloy DJ, Garcia-Dorado D, B\u00f8tker HE, Davidson SM, Downey J, Engel FB, Jennings R, Lecour S, Leor J, Madonna R, Ovize M, Perrino C, Prunier F, Schulz R, Sluijter JPG, Van Laake LW, Vinten-Johansen J, Yellon DM, Ytrehus K, Heusch G, Ferdinandy P (2017) Novel targets and future strategies for acute cardioprotection: position paper of the European Society of Cardiology working group on cellular biology of the heart. Cardiovasc Res 113(6):564\u2013585. https:\/\/doi.org\/10.1093\/cvr\/cvx049","journal-title":"Cardiovasc Res"},{"issue":"3","key":"4192_CR69","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1093\/eurheartj\/eht346","volume":"35","author":"DM Hong","year":"2014","unstructured":"Hong DM, Lee EH, Kim HJ, Min JJ, Chin JH, Choi DK, Bahk JH, Sim JY, Choi IC, Jeon Y (2014) Does remote ischaemic preconditioning with postconditioning improve clinical outcomes of patients undergoing cardiac surgery? Remote ischaemic preconditioning with postconditioning outcome trial. Eur Heart J 35(3):176\u2013183. https:\/\/doi.org\/10.1093\/eurheartj\/eht346","journal-title":"Eur Heart J"},{"issue":"15","key":"4192_CR70","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1056\/NEJMoa1413534","volume":"373","author":"DJ Hausenloy","year":"2015","unstructured":"Hausenloy DJ, Candilio L, Evans R, Ariti C, Jenkins DP, Kolvekar S, Knight R, Kunst G, Laing C, Nicholas J, Pepper J, Robertson S, Xenou M, Clayton T, Yellon DM, Trial Investigators ERICCA (2015) Remote ischemic preconditioning and outcomes of cardiac surgery. N Engl J Med 373(15):1408\u20131417. https:\/\/doi.org\/10.1056\/NEJMoa1413534","journal-title":"N Engl J Med"},{"issue":"15","key":"4192_CR71","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1056\/NEJMoa1413579","volume":"373","author":"P Meybohm","year":"2015","unstructured":"Meybohm P, Bein B, Brosteanu O, Cremer J, Gruenewald M, Stoppe C, Coburn M, Schaelte G, B\u00f6ning A, Niemann B, Roesner J, Kletzin F, Strouhal U, Reyher C, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Stehr SN, Kortgen A, Wittmann M, Baumgarten G, Meyer-Treschan T, Kienbaum P, Heringlake M, Sch\u00f6n J, Sander M, Treskatsch S, Smul T, Wolwender E, Schilling T, Fuernau G, Hasenclever D, Zacharowski K, RIPHeart Study Collaborators (2015) A multicenter trial of remote ischemic preconditioning for heart surgery. N Engl J Med 373(15):1397\u20131407. https:\/\/doi.org\/10.1056\/NEJMoa1413579","journal-title":"N Engl J Med"},{"key":"4192_CR72","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/j.1399-6576.2011.02585.x","volume":"56","author":"E Kottenberg","year":"2012","unstructured":"Kottenberg E, Thielmann M, Bergmann L, Heine T, Jakob H, Heusch G, Peters J (2012) Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial. Acta Anaesthesiol Scand 56:30\u201338. https:\/\/doi.org\/10.1111\/j.1399-6576.2011.02585.x","journal-title":"Acta Anaesthesiol Scand"},{"issue":"1","key":"4192_CR73","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.jtcvs.2013.01.005","volume":"147","author":"E Kottenberg","year":"2014","unstructured":"Kottenberg E, Musiolik J, Thielmann M, Jakob H, Peters J, Heusch G (2014) Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting. J Thorac Cardiovasc Surg 147(1):376\u2013382. https:\/\/doi.org\/10.1016\/j.jtcvs.2013.01.005","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"6","key":"4192_CR74","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/j.ejcts.2009.02.014","volume":"35","author":"V Venugopal","year":"2009","unstructured":"Venugopal V, Ludman A, Yellon DM, Hausenloy DJ (2009) \u2018Conditioning\u2019 the heart during surgery. Eur J Cardiothorac Surg 35(6):977\u2013987. https:\/\/doi.org\/10.1016\/j.ejcts.2009.02.014","journal-title":"Eur J Cardiothorac Surg"},{"key":"4192_CR75","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.redox.2017.03.010","volume":"12","author":"C Dezfulian","year":"2017","unstructured":"Dezfulian C, Taft M, Corey C, Hill G, Krehel N, Rittenberger JC, Guyette FX, Shiva S (2017) Biochemical signaling by remote ischemic conditioning of the arm versus thigh: is one raise of the cuff enough? Redox Biol 12:491\u2013498. https:\/\/doi.org\/10.1016\/j.redox.2017.03.010","journal-title":"Redox Biol"},{"issue":"25","key":"4192_CR76","doi-asserted-by":"publisher","first-page":"2764","DOI":"10.1016\/j.jacc.2015.02.082","volume":"65","author":"DM Yellon","year":"2015","unstructured":"Yellon DM, Ackbarkhan AK, Balgobin V, Bulluck H, Deelchand A, Dhuny MR, Domah N, Gaoneadry D, Jagessur RK, Joonas N, Kowlessur S, Lutchoo J, Nicholas JM, Pauvaday K, Shamloll O, Walker JM, Hausenloy DJ (2015) Remote ischemic conditioning reduces myocardial infarct size in STEMI patients treated by thrombolysis. J Am Coll Cardiol 65(25):2764. https:\/\/doi.org\/10.1016\/j.jacc.2015.02.082","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"4192_CR77","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s13019-019-0834-x","volume":"14","author":"R Gong","year":"2019","unstructured":"Gong R, Wu YQ (2019) Remote ischemic conditioning during primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis. J Cardiothorac Surg 14(1):14. https:\/\/doi.org\/10.1186\/s13019-019-0834-x","journal-title":"J Cardiothorac Surg"},{"key":"4192_CR78","doi-asserted-by":"publisher","first-page":"6907167","DOI":"10.1155\/2017\/6907167","volume":"2017","author":"X Wang","year":"2017","unstructured":"Wang X, Kong N, Zhou C, Mungun D, Iyan Z, Guo Y, Yang Z (2017) Effect of remote ischemic preconditioning on perioperative cardiac events in patients undergoing elective percutaneous coronary intervention: a meta-analysis of 16 randomized trials. Cardiol Res Pract 2017:6907167. https:\/\/doi.org\/10.1155\/2017\/6907167","journal-title":"Cardiol Res Pract"},{"issue":"7","key":"4192_CR79","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/j.amjmed.2014.02.012","volume":"127","author":"V Manchurov","year":"2014","unstructured":"Manchurov V, Ryazankina N, Khmara T, Skrypnik D, Reztsov R, Vasilieva E, Shpektor A (2014) Remote ischemic preconditioning and endothelial function in patients with acute myocardial infarction and primary PCI. Am J Med 127(7):670\u2013673. https:\/\/doi.org\/10.1016\/j.amjmed.2014.02.012","journal-title":"Am J Med"},{"issue":"10207","key":"4192_CR80","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1016\/S0140-6736(19)32039-2","volume":"394","author":"DJ Hausenloy","year":"2019","unstructured":"Hausenloy DJ, Kharbanda RK, M\u00f8ller UK, Ramlall M, Aar\u00f8e J, Butler R, Bulluck H, Clayton T, Dana A, Dodd M, Engstrom T, Evans R, Lassen JF, Christensen EF, Garcia-Ruiz JM, Gorog DA, Hjort J, Houghton RF, Ibanez B, Knight R, Lippert FK, L\u00f8nborg JT, Maeng M, Milasinovic D, More R, Nicholas JM, Jensen LO, Perkins A, Radovanovic N, Rakhit RD, Ravkilde J, Ryding AD, Schmidt MR, Riddervold IS, S\u00f8rensen HT, Stankovic G, Varma M, Webb I, Terkelsen CJ, Greenwood JP, Yellon DM, B\u00f8tker HE, CONDI-2\/ERIC-PPCI Investigators (2019) Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2\/ERIC-PPCI): a single-blind randomised controlled trial. Lancet 394(10207):1415\u20131424. https:\/\/doi.org\/10.1016\/S0140-6736(19)32039-2","journal-title":"Lancet"},{"key":"4192_CR81","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1093\/cvr\/cvp033","volume":"83","author":"K Boengler","year":"2009","unstructured":"Boengler K, Schulz R, Heusch G (2009) Loss of cardioprotection with ageing. Cardiovasc Res 83:247\u2013261","journal-title":"Cardiovasc Res"},{"issue":"2","key":"4192_CR82","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1093\/cvr\/cvp033","volume":"97","author":"RV Jensen","year":"2013","unstructured":"Jensen RV, Zachara NE, Nielsen PH, Kimose HH, Kristiansen SB, B\u00f8tker HE (2013) Impact of O-GlcNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients. Cardiovasc Res 97(2):369\u2013378. https:\/\/doi.org\/10.1093\/cvr\/cvp033","journal-title":"Cardiovasc Res"},{"key":"4192_CR83","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s00125-010-1970-y","volume":"54","author":"SB Kristiansen","year":"2011","unstructured":"Kristiansen SB, Lofgren B, Nielsen JM, Stottrup NB, Buhl ES, Nielsen-Kudsk JE, Nielsen TT, Rungby J, Flyvbjerg A, B\u00f8tker HE (2011) Comparison of two sulfonylureas with high and low myocardial K (ATP) channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes. Diabetologia 54:451\u2013458. https:\/\/doi.org\/10.1007\/s00125-010-1970-y","journal-title":"Diabetologia"},{"key":"4192_CR84","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1111\/aas.12278","volume":"58","author":"E Kottenberg","year":"2014","unstructured":"Kottenberg E, Thielmann M, Kleinbongard P, Frey UH, Heine T, Jakob H, Heusch G, Peters J (2014) Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisation. Acta Anaesthesiol Scand 58:453\u2013462. https:\/\/doi.org\/10.1111\/aas.12278","journal-title":"Acta Anaesthesiol Scand"},{"key":"4192_CR85","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1007\/s00395-011-0216-6","volume":"106","author":"Y Ye","year":"2011","unstructured":"Ye Y, Perez-Polo JR, Aguilar D, Birnbaum Y (2011) The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury. Basic Res Cardiol 106:925\u2013952. https:\/\/doi.org\/10.1007\/s00395-011-0216-6","journal-title":"Basic Res Cardiol"},{"key":"4192_CR86","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.1161\/CIRCULATIONAHA.107.697979","volume":"117","author":"RA Kloner","year":"2008","unstructured":"Kloner RA, Nesto RW (2008) Glucose-insulin-potassium for acute myocardial infarction: continuing controversy over cardioprotection. Circulation 117:2523\u20132533. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.107.697979","journal-title":"Circulation"},{"key":"4192_CR87","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s10557-013-6504-7","volume":"28","author":"CPH Lexis","year":"2014","unstructured":"Lexis CPH, Wieringa WG, Hiemstra B, van Deursen V, Lipsic E, van der Harst P, van Veldhuisen DJ, van der Horst IC (2014) Chronic metformin treatment is associated with reduced myocardial infarct size in diabetic patients with ST-segment elevation myocardial infarction. Cardiovasc Drugs Ther 28:163\u2013171. https:\/\/doi.org\/10.1007\/s10557-013-6504-7","journal-title":"Cardiovasc Drugs Ther"},{"issue":"2","key":"4192_CR88","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1093\/cvr\/cvv171","volume":"107","author":"JJ Alburquerque-B\u00e9jar","year":"2015","unstructured":"Alburquerque-B\u00e9jar JJ, Barba I, Inserte J, Mir\u00f3-Casas E, Ruiz-Meana M, Poncelas M, Vilardosa \u00da, Valls-Lacalle L, Rodr\u00edguez-Sinovas A, Garcia-Dorado D (2015) Combination therapy with remote ischaemic conditioning and insulin or exenatide enhances infarct size limitation in pigs. Cardiovasc Res 107(2):246\u2013254. https:\/\/doi.org\/10.1093\/cvr\/cvv171","journal-title":"Cardiovasc Res"},{"key":"4192_CR89","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.jacbts.2018.10.002","volume":"4","author":"VG Lim","year":"2019","unstructured":"Lim VG, Bell RM, Arjun S, Kolatsi-Joannou M, Long DA, Yellon DM (2019) SGLT2 Inhibitor, canagliflozin, attenuates myocardial infarction in the diabetic and nondiabetic heart. J Am Col Cardiol Basic Transl Sci 4:15\u201326. https:\/\/doi.org\/10.1016\/j.jacbts.2018.10.002","journal-title":"J Am Col Cardiol Basic Transl Sci"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-021-04192-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-021-04192-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-021-04192-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T21:40:41Z","timestamp":1699134041000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-021-04192-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,14]]},"references-count":89,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["4192"],"URL":"https:\/\/doi.org\/10.1007\/s11010-021-04192-4","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,14]]},"assertion":[{"value":"11 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have not conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The procedures used in the mentioned studies, in which we are authors were approved by the Animal Care and Research Committee of the University of Buenos Aires (Protocol number 2948\/10) and were in compliance with the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health in 2011.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All the authors gave their consent to participate and publish the review.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}