{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T18:28:17Z","timestamp":1788028097395,"version":"build-2784847793"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL144125"],"award-info":[{"award-number":["R01 HL144125"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017932","name":"Western University of Health Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017932","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Atherosclerosis is a multifactorial inflammatory disease characterized by the development of plaque formation leading to occlusion of the vessel and hypoxia of the tissue supplied by the vessel. Chronic inflammation and altered collagen expression render stable plaque to unstable and increase plaque vulnerability. Thinned and weakened fibrous cap results in plaque rupture and formation of thrombosis and emboli formation leading to acute ischemic events such as stroke and myocardial infarction. Inflammatory mediators including TREM-1, TLRs, MMPs, and immune cells play a critical role in plaque vulnerability. Among the other inflammatory mediators, oncostatin-M (OSM), a pro-inflammatory cytokine, play an important role in the development and progression of atherosclerosis, however, the role of OSM in plaque vulnerability and extracellular matrix remodeling (ECM) is not well understood and studied. Since ECM remodeling plays an important role in atherosclerosis and plaque vulnerability, a detailed investigation on the role of OSM in ECM remodeling and plaque vulnerability is critical. This is important because the role of OSM has been discussed in the context of proliferation of vascular smooth muscle cells and regulation of cytokine expression but the role of OSM is scarcely discussed in relation to ECM remodeling and plaque vulnerability. This review focuses on critically discussing the role of OSM in ECM remodeling and plaque vulnerability.\n<\/jats:p>","DOI":"10.1007\/s11010-023-04673-8","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T15:03:48Z","timestamp":1677683028000},"page":"2451-2460","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Role of oncostatin-M in ECM remodeling and plaque vulnerability"],"prefix":"10.1007","volume":"478","author":[{"given":"Parth","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6286-2341","authenticated-orcid":false,"given":"Vikrant","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5445-0013","authenticated-orcid":false,"given":"Devendra K.","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"issue":"4","key":"4673_CR1","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1161\/CIRCRESAHA.115.307611","volume":"118","author":"W Herrington","year":"2016","unstructured":"Herrington W, Lacey B, Sherliker P, Armitage J, Lewington S (2016) Epidemiology of atherosclerosis and the potential to reduce the global burden of atherothrombotic disease. Circ Res 118(4):535\u201346. https:\/\/doi.org\/10.1161\/CIRCRESAHA.115.307611","journal-title":"Circ Res"},{"issue":"20","key":"4673_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms21207609","volume":"21","author":"D Kuriakose","year":"2020","unstructured":"Kuriakose D, Xiao Z (2020) Pathophysiology and treatment of stroke: present status and future perspectives. Int J Mol Sci 21(20):1. https:\/\/doi.org\/10.3390\/ijms21207609","journal-title":"Int J Mol Sci"},{"issue":"8","key":"4673_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms21082992","volume":"21","author":"NV Mushenkova","year":"2020","unstructured":"Mushenkova NV, Summerhill VI, Zhang D, Romanenko EB, Grechko AV, Orekhov AN (2020) current advances in the diagnostic imaging of atherosclerosis: insights into the pathophysiology of vulnerable plaque. Int J Mol Sci 21(8):1. https:\/\/doi.org\/10.3390\/ijms21082992","journal-title":"Int J Mol Sci"},{"issue":"5","key":"4673_CR4","doi-asserted-by":"publisher","first-page":"e0154802","DOI":"10.1371\/journal.pone.0154802","volume":"11","author":"V Rai","year":"2016","unstructured":"Rai V, Rao VH, Shao Z, Agrawal DK (2016) Dendritic cells expressing triggering receptor expressed on myeloid cells-1 correlate with plaque stability in symptomatic and asymptomatic patients with carotid stenosis. PLoS ONE 11(5):e0154802. https:\/\/doi.org\/10.1371\/journal.pone.0154802","journal-title":"PLoS ONE"},{"key":"4673_CR5","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.atherosclerosis.2016.03.021","volume":"248","author":"VH Rao","year":"2016","unstructured":"Rao VH, Rai V, Stoupa S, Subramanian S, Agrawal DK (2016) Tumor necrosis factor-alpha regulates triggering receptor expressed on myeloid cells-1-dependent matrix metalloproteinases in the carotid plaques of symptomatic patients with carotid stenosis. Atherosclerosis 248:160\u20139. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2016.03.021","journal-title":"Atherosclerosis"},{"key":"4673_CR6","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.dib.2016.05.047","volume":"8","author":"VH Rao","year":"2016","unstructured":"Rao VH, Rai V, Stoupa S, Subramanian S, Agrawal DK (2016) Data on TREM-1 activation destabilizing carotid plaques. Data Brief 8:230\u20134. https:\/\/doi.org\/10.1016\/j.dib.2016.05.047","journal-title":"Data Brief"},{"issue":"6","key":"4673_CR7","doi-asserted-by":"publisher","first-page":"H1075","DOI":"10.1152\/ajpheart.00378.2015","volume":"309","author":"VH Rao","year":"2015","unstructured":"Rao VH, Rai V, Stoupa S, Agrawal DK (2015) Blockade of Ets-1 attenuates epidermal growth factor-dependent collagen loss in human carotid plaque smooth muscle cells. Am J Physiol Heart Circ Physiol 309(6):H1075-86. https:\/\/doi.org\/10.1152\/ajpheart.00378.2015","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"4673_CR8","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/978-3-031-14952-8_18","volume-title":"The renin angiotensin system in cardiovascular disease","author":"V Rai","year":"2023","unstructured":"Rai V, Agrawal DK (2023) Renin angiotensin system in the maturation and failure of arterio-venous fistula. The renin angiotensin system in cardiovascular disease. Springer, pp 291\u2013303"},{"issue":"6","key":"4673_CR9","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1111\/joim.12296","volume":"276","author":"L Badimon","year":"2014","unstructured":"Badimon L, Vilahur G (2014) Thrombosis formation on atherosclerotic lesions and plaque rupture. J Intern Med 276(6):618\u201332. https:\/\/doi.org\/10.1111\/joim.12296","journal-title":"J Intern Med"},{"issue":"3","key":"4673_CR10","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/s0735-1097(99)00604-x","volume":"35","author":"PA Tunick","year":"2000","unstructured":"Tunick PA, Kronzon I (2000) Atheromas of the thoracic aorta: clinical and therapeutic update. J Am Coll Cardiol 35(3):545\u201354. https:\/\/doi.org\/10.1016\/s0735-1097(99)00604-x","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"4673_CR11","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1111\/j.1538-7836.2008.02948.x","volume":"6","author":"M Kikura","year":"2008","unstructured":"Kikura M, Oikawa F, Yamamoto K, Iwamoto T, Tanaka KA, Sato S et al (2008) Myocardial infarction and cerebrovascular accident following non-cardiac surgery: differences in postoperative temporal distribution and risk factors. J Thromb Haemost 6(5):742\u20138. https:\/\/doi.org\/10.1111\/j.1538-7836.2008.02948.x","journal-title":"J Thromb Haemost"},{"issue":"6","key":"4673_CR12","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.hlc.2013.03.001","volume":"22","author":"K Sakakura","year":"2013","unstructured":"Sakakura K, Nakano M, Otsuka F, Ladich E, Kolodgie FD, Virmani R (2013) Pathophysiology of atherosclerosis plaque progression. Heart Lung Circ 22(6):399\u2013411. https:\/\/doi.org\/10.1016\/j.hlc.2013.03.001","journal-title":"Heart Lung Circ"},{"issue":"5","key":"4673_CR13","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1111\/joim.12414","volume":"278","author":"I Goncalves","year":"2015","unstructured":"Goncalves I, den Ruijter H, Nahrendorf M, Pasterkamp G (2015) Detecting the vulnerable plaque in patients. J Intern Med 278(5):520\u201330. https:\/\/doi.org\/10.1111\/joim.12414","journal-title":"J Intern Med"},{"issue":"10","key":"4673_CR14","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1139\/cjpp-2016-0664","volume":"95","author":"V Rai","year":"2017","unstructured":"Rai V, Agrawal DK (2017) The role of damage- and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques. Can J Physiol Pharmacol 95(10):1245\u201353. https:\/\/doi.org\/10.1139\/cjpp-2016-0664","journal-title":"Can J Physiol Pharmacol"},{"issue":"4","key":"4673_CR15","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1016\/j.ecl.2017.07.009","volume":"46","author":"V Rai","year":"2017","unstructured":"Rai V, Agrawal DK (2017) Role of vitamin D in cardiovascular diseases. Endocrinol Metab Clin 46(4):1039\u20131059","journal-title":"Endocrinol Metab Clin"},{"issue":"1","key":"4673_CR16","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s12967-018-1479-6","volume":"16","author":"X Zeng","year":"2018","unstructured":"Zeng X, Guo R, Dong M, Zheng J, Lin H, Lu H (2018) Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression. J Transl Med 16(1):106. https:\/\/doi.org\/10.1186\/s12967-018-1479-6","journal-title":"J Transl Med"},{"issue":"1","key":"4673_CR17","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s10557-008-6147-2","volume":"23","author":"PK Shah","year":"2009","unstructured":"Shah PK (2009) Inflammation and plaque vulnerability. Cardiovasc Drugs Ther 23(1):31\u201340","journal-title":"Cardiovasc Drugs Ther"},{"issue":"11","key":"4673_CR18","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1113\/EP085567","volume":"101","author":"AC Newby","year":"2016","unstructured":"Newby AC (2016) Metalloproteinase production from macrophages\u2014a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction. Exp Physiol 101(11):1327\u201337. https:\/\/doi.org\/10.1113\/EP085567","journal-title":"Exp Physiol"},{"issue":"9","key":"4673_CR19","doi-asserted-by":"publisher","first-page":"8663","DOI":"10.1007\/s11033-022-07703-8","volume":"49","author":"H Singh","year":"2022","unstructured":"Singh H, Rai V, Agrawal DK (2022) LPS and oxLDL-induced S100A12 and RAGE expression in carotid arteries of atherosclerotic Yucatan microswine. Mol Biol Rep 49(9):8663\u201372. https:\/\/doi.org\/10.1007\/s11033-022-07703-8","journal-title":"Mol Biol Rep"},{"issue":"5","key":"4673_CR20","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1194\/jlr.M074112","volume":"58","author":"X Zhang","year":"2017","unstructured":"Zhang X, Li J, Qin JJ, Cheng WL, Zhu X, Gong FH et al (2017) Oncostatin M receptor beta deficiency attenuates atherogenesis by inhibiting JAK2\/STAT3 signaling in macrophages. J Lipid Res 58(5):895\u2013906. https:\/\/doi.org\/10.1194\/jlr.M074112","journal-title":"J Lipid Res"},{"issue":"8","key":"4673_CR21","doi-asserted-by":"publisher","first-page":"e0221477","DOI":"10.1371\/journal.pone.0221477","volume":"14","author":"DV Keulen","year":"2019","unstructured":"Keulen DV, Pouwer MG, Emilsson V, Matic LP, Pieterman EJ, Hedin U et al (2019) Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans. PLoS ONE 14(8):e0221477. https:\/\/doi.org\/10.1371\/journal.pone.0221477","journal-title":"PLoS ONE"},{"key":"4673_CR22","doi-asserted-by":"publisher","first-page":"100829","DOI":"10.1016\/j.ijcha.2021.100829","volume":"35","author":"S Ikeda","year":"2021","unstructured":"Ikeda S, Sato K, Takeda M, Miki K, Aizawa K, Takada T et al (2021) Oncostatin M is a novel biomarker for coronary artery disease\u2014a possibility as a screening tool of silent myocardial ischemia for diabetes mellitus. Int J Cardiol Heart Vasc 35:100829. https:\/\/doi.org\/10.1016\/j.ijcha.2021.100829","journal-title":"Int J Cardiol Heart Vasc"},{"issue":"2","key":"4673_CR23","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.atherosclerosis.2011.02.003","volume":"216","author":"A Albasanz-Puig","year":"2011","unstructured":"Albasanz-Puig A, Murray J, Preusch M, Coan D, Namekata M, Patel Y et al (2011) Oncostatin M is expressed in atherosclerotic lesions: a role for Oncostatin M in the pathogenesis of atherosclerosis. Atherosclerosis 216(2):292\u20138. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2011.02.003","journal-title":"Atherosclerosis"},{"issue":"13","key":"4673_CR24","doi-asserted-by":"publisher","first-page":"2812","DOI":"10.1182\/blood-2009-01-200915","volume":"114","author":"SP Kastl","year":"2009","unstructured":"Kastl SP, Speidl WS, Katsaros KM, Kaun C, Rega G, Assadian A et al (2009) Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation. Blood 114(13):2812\u20138. https:\/\/doi.org\/10.1182\/blood-2009-01-200915","journal-title":"Blood"},{"issue":"4","key":"4673_CR25","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1161\/01.ATV.0000060891.31516.24","volume":"23","author":"T Nagata","year":"2003","unstructured":"Nagata T, Kai H, Shibata R, Koga M, Yoshimura A, Imaizumi T, Oncostatin M (2003) an interleukin-6 family cytokine, upregulates matrix metalloproteinase-9 through the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cultured smooth muscle cells. Arterioscler Thromb Vasc Biol 23(4):588\u201393. https:\/\/doi.org\/10.1161\/01.ATV.0000060891.31516.24","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1","key":"4673_CR26","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1080\/03008207.2018.1500558","volume":"60","author":"L Stawski","year":"2019","unstructured":"Stawski L, Trojanowska M (2019) Oncostatin M and its role in fibrosis. Connect Tissue Res 60(1):40\u20139. https:\/\/doi.org\/10.1080\/03008207.2018.1500558","journal-title":"Connect Tissue Res"},{"issue":"22","key":"4673_CR27","doi-asserted-by":"publisher","first-page":"6424","DOI":"10.7150\/thno.35528","volume":"9","author":"Q Chen","year":"2019","unstructured":"Chen Q, Lv J, Yang W, Xu B, Wang Z, Yu Z et al (2019) Targeted inhibition of STAT3 as a potential treatment strategy for atherosclerosis. Theranostics 9(22):6424\u201342. https:\/\/doi.org\/10.7150\/thno.35528","journal-title":"Theranostics"},{"issue":"5","key":"4673_CR28","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1111\/joim.13034","volume":"287","author":"S Holm Nielsen","year":"2020","unstructured":"Holm Nielsen S, Jonasson L, Kalogeropoulos K, Karsdal MA, Reese-Petersen AL, Auf Dem Keller U et al (2020) Exploring the role of extracellular matrix proteins to develop biomarkers of plaque vulnerability and outcome. J Intern Med 287(5):493\u2013513. https:\/\/doi.org\/10.1111\/joim.13034","journal-title":"J Intern Med"},{"issue":"6","key":"4673_CR29","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/CRD.0b013e31828c5ced","volume":"21","author":"DA Chistiakov","year":"2013","unstructured":"Chistiakov DA, Sobenin IA, Orekhov AN (2013) Vascular extracellular matrix in atherosclerosis. Cardiol Rev 21(6):270\u201388. https:\/\/doi.org\/10.1097\/CRD.0b013e31828c5ced","journal-title":"Cardiol Rev"},{"issue":"1","key":"4673_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1152\/physrev.00048.2003","volume":"85","author":"AC Newby","year":"2005","unstructured":"Newby AC (2005) Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. Physiol Rev 85(1):1\u201331. https:\/\/doi.org\/10.1152\/physrev.00048.2003","journal-title":"Physiol Rev"},{"issue":"2","key":"4673_CR31","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.3892\/etm.2017.5623","volume":"15","author":"W Hu","year":"2018","unstructured":"Hu W, Wei R, Wang L, Lu J, Liu H, Zhang W (2018) Correlations of MMP-1, MMP-3, and MMP-12 with the degree of atherosclerosis, plaque stability and cardiovascular and cerebrovascular events. Exp Ther Med 15(2):1994\u20138. https:\/\/doi.org\/10.3892\/etm.2017.5623","journal-title":"Exp Ther Med"},{"issue":"8","key":"4673_CR32","doi-asserted-by":"publisher","first-page":"456","DOI":"10.21037\/atm-22-560","volume":"10","author":"C Liu","year":"2022","unstructured":"Liu C, Wu J, Jia H, Lu C, Liu J, Li Y et al (2022) Oncostatin M promotes the ox-LDL-induced activation of NLRP3 inflammasomes via the NF-kappaB pathway in THP-1 macrophages and promotes the progression of atherosclerosis. Ann Transl Med 10(8):456. https:\/\/doi.org\/10.21037\/atm-22-560","journal-title":"Ann Transl Med"},{"issue":"3","key":"4673_CR33","doi-asserted-by":"publisher","first-page":"152220","DOI":"10.1016\/j.imbio.2022.152220","volume":"227","author":"A Moeinafshar","year":"2022","unstructured":"Moeinafshar A, Razi S, Rezaei N (2022) Interleukin 17, the double-edged sword in atherosclerosis. Immunobiology 227(3):152220. https:\/\/doi.org\/10.1016\/j.imbio.2022.152220","journal-title":"Immunobiology"},{"issue":"3","key":"4673_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/biom8030080","volume":"8","author":"Y Zhu","year":"2018","unstructured":"Zhu Y, Xian X, Wang Z, Bi Y, Chen Q, Han X et al (2018) Research progress on the relationship between atherosclerosis and inflammation. Biomolecules 8(3):1. https:\/\/doi.org\/10.3390\/biom8030080","journal-title":"Biomolecules"},{"issue":"10","key":"4673_CR35","doi-asserted-by":"publisher","first-page":"e0204911","DOI":"10.1371\/journal.pone.0204911","volume":"13","author":"D van Keulen","year":"2018","unstructured":"van Keulen D, Pouwer MG, Pasterkamp G, van Gool AJ, Sollewijn Gelpke MD, Princen HMG et al (2018) Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice. PLoS ONE 13(10):e0204911. https:\/\/doi.org\/10.1371\/journal.pone.0204911","journal-title":"PLoS ONE"},{"issue":"19","key":"4673_CR36","doi-asserted-by":"publisher","first-page":"5060","DOI":"10.1158\/0008-5472.CAN-21-0345","volume":"81","author":"HH Nguyen-Tran","year":"2021","unstructured":"Nguyen-Tran HH, Nguyen TN, Chen CY, Hsu T (2021) Endothelial reprogramming stimulated by Oncostatin M promotes inflammation and tumorigenesis in VHL-deficient kidney tissue. Cancer Res 81(19):5060\u201373. https:\/\/doi.org\/10.1158\/0008-5472.CAN-21-0345","journal-title":"Cancer Res"},{"issue":"7","key":"4673_CR37","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1194\/jlr.M036343","volume":"54","author":"P Wiesner","year":"2013","unstructured":"Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS et al (2013) MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res 54(7):1877\u201383. https:\/\/doi.org\/10.1194\/jlr.M036343","journal-title":"J Lipid Res"},{"issue":"4","key":"4673_CR38","doi-asserted-by":"publisher","first-page":"171","DOI":"10.4161\/cam.1.4.5321","volume":"1","author":"Z Chi","year":"2007","unstructured":"Chi Z, Melendez AJ (2007) Role of cell adhesion molecules and immune-cell migration in the initiation, onset and development of atherosclerosis. Cell Adh Migr 1(4):171\u20135. https:\/\/doi.org\/10.4161\/cam.1.4.5321","journal-title":"Cell Adh Migr"},{"issue":"11","key":"4673_CR39","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1093\/jnen\/60.11.1087","volume":"60","author":"K Ruprecht","year":"2001","unstructured":"Ruprecht K, Kuhlmann T, Seif F, Hummel V, Kruse N, Bruck W et al (2001) Effects of oncostatin M on human cerebral endothelial cells and expression in inflammatory brain lesions. J Neuropathol Exp Neurol 60(11):1087\u201398. https:\/\/doi.org\/10.1093\/jnen\/60.11.1087","journal-title":"J Neuropathol Exp Neurol"},{"issue":"21","key":"4673_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms232113638","volume":"23","author":"RM Chiorescu","year":"2022","unstructured":"Chiorescu RM, Mocan M, Inceu AI, Buda AP, Blendea D, Vlaicu SI (2022) Vulnerable atherosclerotic plaque: is there a molecular signature? Int J Mol Sci 23(21):1. https:\/\/doi.org\/10.3390\/ijms232113638","journal-title":"Int J Mol Sci"},{"issue":"2","key":"4673_CR41","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/s0021-9150(00)00506-2","volume":"154","author":"G Barillari","year":"2001","unstructured":"Barillari G, Albonici L, Incerpi S, Bogetto L, Pistritto G, Volpi A et al (2001) Inflammatory cytokines stimulate vascular smooth muscle cells locomotion and growth by enhancing alpha5beta1 integrin expression and function. Atherosclerosis 154(2):377\u201385. https:\/\/doi.org\/10.1016\/s0021-9150(00)00506-2","journal-title":"Atherosclerosis"},{"issue":"8","key":"4673_CR42","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1161\/01.atv.19.8.1835","volume":"19","author":"M Vasse","year":"1999","unstructured":"Vasse M, Pourtau J, Trochon V, Muraine M, Vannier JP, Lu H et al (1999) Oncostatin M induces angiogenesis in vitro and in vivo. Arterioscler Thromb Vasc Biol 19(8):1835\u201342. https:\/\/doi.org\/10.1161\/01.atv.19.8.1835","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"4673_CR43","doi-asserted-by":"publisher","first-page":"658915","DOI":"10.3389\/fcvm.2021.658915","volume":"8","author":"D van Keulen","year":"2021","unstructured":"van Keulen D, van Koeverden ID, Boltjes A, Princen HMG, van Gool AJ, de Borst GJ et al (2021) Common variants associated with osmr expression contribute to carotid plaque vulnerability, but not to cardiovascular disease in humans. Front Cardiovasc Med 8:658915. https:\/\/doi.org\/10.3389\/fcvm.2021.658915","journal-title":"Front Cardiovasc Med"},{"issue":"4","key":"4673_CR44","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/j.jvs.2017.08.075","volume":"67","author":"H Dong","year":"2018","unstructured":"Dong H, Du T, Premaratne S, Zhao CX, Tian Q, Li Y et al (2018) Relationship between ADAMTS4 and carotid atherosclerotic plaque vulnerability in humans. J Vasc Surg 67(4):1120\u20136. https:\/\/doi.org\/10.1016\/j.jvs.2017.08.075","journal-title":"J Vasc Surg"},{"issue":"4","key":"4673_CR45","doi-asserted-by":"publisher","first-page":"294","DOI":"10.5551\/jat.RV17020","volume":"25","author":"A Shioi","year":"2018","unstructured":"Shioi A, Ikari Y (2018) Plaque calcification during atherosclerosis progression and regression. J Atheroscler Thromb 25(4):294\u2013303. https:\/\/doi.org\/10.5551\/jat.RV17020","journal-title":"J Atheroscler Thromb"},{"issue":"19","key":"4673_CR46","doi-asserted-by":"publisher","first-page":"3741","DOI":"10.1111\/bph.14779","volume":"176","author":"JL Harman","year":"2019","unstructured":"Harman JL, Jorgensen HF (2019) The role of smooth muscle cells in plaque stability: therapeutic targeting potential. Br J Pharmacol 176(19):3741\u201353. https:\/\/doi.org\/10.1111\/bph.14779","journal-title":"Br J Pharmacol"},{"issue":"19","key":"4673_CR47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms231912012","volume":"23","author":"V Rai","year":"2022","unstructured":"Rai V, Singh H, Agrawal DK (2022) Targeting the crosstalk of immune response and vascular smooth muscle cells phenotype switch for arteriovenous fistula maturation. Int J Mol Sci 23(19):1. https:\/\/doi.org\/10.3390\/ijms231912012","journal-title":"Int J Mol Sci"},{"issue":"4","key":"4673_CR48","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1161\/CIRCRESAHA.115.306361","volume":"118","author":"MR Bennett","year":"2016","unstructured":"Bennett MR, Sinha S, Owens GK (2016) Vascular smooth muscle cells in atherosclerosis. Circ Res 118(4):692\u2013702. https:\/\/doi.org\/10.1161\/CIRCRESAHA.115.306361","journal-title":"Circ Res"},{"issue":"7","key":"4673_CR49","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1002\/jcb.25088","volume":"116","author":"Y Kakutani","year":"2015","unstructured":"Kakutani Y, Shioi A, Shoji T, Okazaki H, Koyama H, Emoto M et al (2015) Oncostatin M promotes osteoblastic differentiation of human vascular smooth muscle cells through JAK3-STAT3 pathway. J Cell Biochem 116(7):1325\u201333. https:\/\/doi.org\/10.1002\/jcb.25088","journal-title":"J Cell Biochem"},{"issue":"6","key":"4673_CR50","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/j.cytogfr.2015.04.003","volume":"26","author":"DP Ramji","year":"2015","unstructured":"Ramji DP, Davies TS (2015) Cytokines in atherosclerosis: key players in all stages of disease and promising therapeutic targets. Cytokine Growth Factor Rev 26(6):673\u201385. https:\/\/doi.org\/10.1016\/j.cytogfr.2015.04.003","journal-title":"Cytokine Growth Factor Rev"},{"issue":"5\u20136","key":"4673_CR51","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/s0753-3322(03)00065-9","volume":"57","author":"MP Jacob","year":"2003","unstructured":"Jacob MP (2003) Extracellular matrix remodeling and matrix metalloproteinases in the vascular wall during aging and in pathological conditions. Biomed Pharmacother 57(5\u20136):195\u2013202. https:\/\/doi.org\/10.1016\/s0753-3322(03)00065-9","journal-title":"Biomed Pharmacother"},{"issue":"4","key":"4673_CR52","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1161\/ATVBAHA.121.316233","volume":"42","author":"A Yurdagul Jr","year":"2022","unstructured":"Yurdagul A Jr (2022) Crosstalk between macrophages and vascular smooth muscle cells in atherosclerotic plaque stability. Arterioscler Thromb Vasc Biol 42(4):372\u201380. https:\/\/doi.org\/10.1161\/ATVBAHA.121.316233","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"4673_CR53","first-page":"167","volume":"85","author":"J Padmanabhan","year":"2012","unstructured":"Padmanabhan J, Gonzalez AL (2012) The effects of extracellular matrix proteins on neutrophil-endothelial interaction\u2013a roadway to multiple therapeutic opportunities. Yale J Biol Med 85(2):167\u201385","journal-title":"Yale J Biol Med"},{"key":"4673_CR54","doi-asserted-by":"publisher","first-page":"111423","DOI":"10.1016\/j.biopha.2021.111423","volume":"138","author":"C Gong","year":"2021","unstructured":"Gong C, Qi Y, Xu Y, Tang X, Liang F, Chen L (2021) Parecoxib improves atherosclerotic plaque stability by suppressing inflammation and inhibiting matrix metalloproteinases production. Biomed Pharmacother 138:111423. https:\/\/doi.org\/10.1016\/j.biopha.2021.111423","journal-title":"Biomed Pharmacother"},{"issue":"4","key":"4673_CR55","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.matbio.2011.04.003","volume":"30","author":"T Hayami","year":"2011","unstructured":"Hayami T, Kapila YL, Kapila S (2011) Divergent upstream osteogenic events contribute to the differential modulation of MG63 cell osteoblast differentiation by MMP-1 (collagenase-1) and MMP-13 (collagenase-3). Matrix Biol 30(4):281\u20139. https:\/\/doi.org\/10.1016\/j.matbio.2011.04.003","journal-title":"Matrix Biol"},{"key":"4673_CR56","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.thromres.2022.06.006","volume":"216","author":"E Falcinelli","year":"2022","unstructured":"Falcinelli E, De Paolis M, Boschetti E, Gresele P (2022) Release of MMP-2 in the circulation of patients with acute coronary syndromes undergoing percutaneous coronary intervention: role of platelets. Thromb Res 216:84\u20139. https:\/\/doi.org\/10.1016\/j.thromres.2022.06.006","journal-title":"Thromb Res"},{"issue":"6","key":"4673_CR57","doi-asserted-by":"publisher","first-page":"H1075","DOI":"10.1152\/ajpheart.00378.2015","volume":"309","author":"VH Rao","year":"2015","unstructured":"Rao VH, Rai V, Stoupa S, Agrawal DK (2015) Blockade of Ets-1 attenuates epidermal growth factor-dependent collagen loss in human carotid plaque smooth muscle cells. Am J Physiol Heart Circul Physiol 309(6):H1075\u2013H1086","journal-title":"Am J Physiol Heart Circul Physiol"},{"key":"4673_CR58","doi-asserted-by":"publisher","first-page":"100236","DOI":"10.1016\/j.mtbio.2022.100236","volume":"14","author":"M Zhang","year":"2022","unstructured":"Zhang M, Xie Z, Long H, Ren K, Hou L, Wang Y et al (2022) Current advances in the imaging of atherosclerotic vulnerable plaque using nanoparticles. Mater Today Bio 14:100236. https:\/\/doi.org\/10.1016\/j.mtbio.2022.100236","journal-title":"Mater Today Bio"},{"issue":"3","key":"4673_CR59","doi-asserted-by":"publisher","first-page":"e0121086","DOI":"10.1371\/journal.pone.0121086","volume":"10","author":"G Asciutto","year":"2015","unstructured":"Asciutto G, Dias NV, Edsfeldt A, Nitulescu M, Persson A, Nilsson M et al (2015) Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke. PLoS ONE 10(3):e0121086. https:\/\/doi.org\/10.1371\/journal.pone.0121086","journal-title":"PLoS ONE"},{"issue":"1","key":"4673_CR60","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s13058-021-01430-x","volume":"23","author":"SC Dinca","year":"2021","unstructured":"Dinca SC, Greiner D, Weidenfeld K, Bond L, Barkan D, Jorcyk CL (2021) Novel mechanism for OSM-promoted extracellular matrix remodeling in breast cancer: LOXL2 upregulation and subsequent ECM alignment. Breast Cancer Res 23(1):56. https:\/\/doi.org\/10.1186\/s13058-021-01430-x","journal-title":"Breast Cancer Res"},{"issue":"22","key":"4673_CR61","doi-asserted-by":"publisher","first-page":"2829","DOI":"10.1161\/01.CIR.0000072792.65250.4A","volume":"107","author":"CM Dollery","year":"2003","unstructured":"Dollery CM, Owen CA, Sukhova GK, Krettek A, Shapiro SD, Libby P (2003) Neutrophil elastase in human atherosclerotic plaques: production by macrophages. Circulation 107(22):2829\u201336. https:\/\/doi.org\/10.1161\/01.CIR.0000072792.65250.4A","journal-title":"Circulation"},{"issue":"3","key":"4673_CR62","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1161\/ATVBAHA.116.308794","volume":"37","author":"Y Li","year":"2017","unstructured":"Li Y, Liu Y, Tian X, Zhang Y, Song H, Liu M et al (2017) Cellular repressor of E1A-stimulated genes is a critical determinant of vascular remodeling in response to angiotensin II. Arterioscler Thromb Vasc Biol 37(3):485\u201394. https:\/\/doi.org\/10.1161\/ATVBAHA.116.308794","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"4673_CR63","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1006\/cyto.2000.0703","volume":"12","author":"O Saijonmaa","year":"2000","unstructured":"Saijonmaa O, Nyman T, Kosonen R, Fyhrquist F (2000) Induction of angiotensin-converting enzyme by oncostatin m in human endothelial cells. Cytokine 12(8):1253\u20136. https:\/\/doi.org\/10.1006\/cyto.2000.0703","journal-title":"Cytokine"},{"issue":"4","key":"4673_CR64","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1165\/rcmb.2012-0460OC","volume":"49","author":"KY Nagahama","year":"2013","unstructured":"Nagahama KY, Togo S, Holz O, Magnussen H, Liu X, Seyama K et al (2013) Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3. Am J Respir Cell Mol Biol 49(4):582\u201391. https:\/\/doi.org\/10.1165\/rcmb.2012-0460OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"4673_CR65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.matbio.2020.05.006","volume":"91\u201392","author":"KY DeLeon-Pennell","year":"2020","unstructured":"DeLeon-Pennell KY, Barker TH, Lindsey ML (2020) Fibroblasts: the arbiters of extracellular matrix remodeling. Matrix Biol 91\u201392:1\u20137. https:\/\/doi.org\/10.1016\/j.matbio.2020.05.006","journal-title":"Matrix Biol"},{"key":"4673_CR66","doi-asserted-by":"publisher","first-page":"609653","DOI":"10.3389\/fbioe.2020.609653","volume":"8","author":"M D\u2019Urso","year":"2020","unstructured":"D\u2019Urso M, Kurniawan NA (2020) Mechanical and physical regulation of fibroblast-myofibroblast transition: from cellular mechanoresponse to tissue pathology. Front Bioeng Biotechnol 8:609653. https:\/\/doi.org\/10.3389\/fbioe.2020.609653","journal-title":"Front Bioeng Biotechnol"},{"issue":"3","key":"4673_CR67","doi-asserted-by":"publisher","first-page":"423","DOI":"10.26502\/jsr.10020237","volume":"5","author":"G Samra","year":"2022","unstructured":"Samra G, Rai V, Agrawal DK (2022) Heterogeneous population of immune cells associated with early thrombosis in arteriovenous fistula. J Surg Res (Houst) 5(3):423\u201334. https:\/\/doi.org\/10.26502\/jsr.10020237","journal-title":"J Surg Res (Houst)"},{"issue":"8","key":"4673_CR68","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1139\/cjpp-2021-0731","volume":"100","author":"G Samra","year":"2022","unstructured":"Samra G, Rai V, Agrawal DK (2022) Innate and adaptive immune cells associate with arteriovenous fistula maturation and failure. Can J Physiol Pharmacol 100(8):716\u201327. https:\/\/doi.org\/10.1139\/cjpp-2021-0731","journal-title":"Can J Physiol Pharmacol"},{"issue":"4","key":"4673_CR69","doi-asserted-by":"publisher","first-page":"345","DOI":"10.12998\/wjcc.v3.i4.345","volume":"3","author":"F Ilhan","year":"2015","unstructured":"Ilhan F, Kalkanli ST (2015) Atherosclerosis and the role of immune cells. World J Clin Cases 3(4):345\u201352. https:\/\/doi.org\/10.12998\/wjcc.v3.i4.345","journal-title":"World J Clin Cases"},{"issue":"17","key":"4673_CR70","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/molecules24173072","volume":"24","author":"H Mangge","year":"2019","unstructured":"Mangge H, Almer G (2019) Immune-mediated inflammation in vulnerable atherosclerotic plaques. Molecules 24(17):1. https:\/\/doi.org\/10.3390\/molecules24173072","journal-title":"Molecules"},{"issue":"11","key":"4673_CR71","doi-asserted-by":"publisher","first-page":"2558","DOI":"10.1161\/ATVBAHA.113.301879","volume":"33","author":"AC Foks","year":"2013","unstructured":"Foks AC, Ran IA, Wasserman L, Frodermann V, Ter Borg MN, de Jager SC et al (2013) T-cell immunoglobulin and mucin domain 3 acts as a negative regulator of atherosclerosis. Arterioscler Thromb Vasc Biol 33(11):2558\u201365. https:\/\/doi.org\/10.1161\/ATVBAHA.113.301879","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"4673_CR72","doi-asserted-by":"publisher","first-page":"108182","DOI":"10.1016\/j.pharmthera.2022.108182","volume":"238","author":"A Panagopoulos","year":"2022","unstructured":"Panagopoulos A, Samant S, Bakhos JJ, Liu M, Khan B, Makadia J et al (2022) Triggering receptor expressed on myeloid cells-1 (TREM-1) inhibition in atherosclerosis. Pharmacol Ther 238:108182. https:\/\/doi.org\/10.1016\/j.pharmthera.2022.108182","journal-title":"Pharmacol Ther"},{"issue":"2","key":"4673_CR73","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1586\/1744666X.2014.866519","volume":"10","author":"CJ Pelham","year":"2014","unstructured":"Pelham CJ, Agrawal DK (2014) Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseases. Expert Rev Clin Immunol 10(2):243\u201356. https:\/\/doi.org\/10.1586\/1744666X.2014.866519","journal-title":"Expert Rev Clin Immunol"},{"issue":"25","key":"4673_CR74","doi-asserted-by":"publisher","first-page":"2776","DOI":"10.1016\/j.jacc.2016.10.015","volume":"68","author":"J Joffre","year":"2016","unstructured":"Joffre J, Potteaux S, Zeboudj L, Loyer X, Boufenzer A, Laurans L et al (2016) Genetic and pharmacological inhibition of TREM-1 limits the development of experimental atherosclerosis. J Am Coll Cardiol 68(25):2776\u201393. https:\/\/doi.org\/10.1016\/j.jacc.2016.10.015","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"4673_CR75","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1007\/s11010-021-04321-z","volume":"477","author":"FG Thankam","year":"2022","unstructured":"Thankam FG, Sanchez DJ, Agrawal DK (2022) Design of the lentivirus-driven sustained LR12 delivery system for TREM-1 inhibition for palliating atherosclerosis. Mol Cell Biochem 477(3):701\u201310. https:\/\/doi.org\/10.1007\/s11010-021-04321-z","journal-title":"Mol Cell Biochem"},{"issue":"6","key":"4673_CR76","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1080\/13543776.2021.1883587","volume":"31","author":"H Singh","year":"2021","unstructured":"Singh H, Rai V, Nooti SK, Agrawal DK (2021) Novel ligands and modulators of triggering receptor expressed on myeloid cells receptor family: 2015\u20132020 updates. Expert Opin Ther Pat 31(6):549\u201361. https:\/\/doi.org\/10.1080\/13543776.2021.1883587","journal-title":"Expert Opin Ther Pat"},{"issue":"5","key":"4673_CR77","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1038\/nm.4307","volume":"23","author":"NR West","year":"2017","unstructured":"West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S et al (2017) Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. Nat Med 23(5):579\u201389. https:\/\/doi.org\/10.1038\/nm.4307","journal-title":"Nat Med"},{"key":"4673_CR78","doi-asserted-by":"publisher","first-page":"107098","DOI":"10.1016\/j.vph.2022.107098","volume":"146","author":"C Caselli","year":"2022","unstructured":"Caselli C, Di Giorgi N, Ragusa R, Lorenzoni V, Smit J, El Mahdiui M et al (2022) Association of MMP9 with adverse features of plaque progression and residual inflammatory risk in patients with chronic coronary syndrome (CCS). Vascul Pharmacol 146:107098. https:\/\/doi.org\/10.1016\/j.vph.2022.107098","journal-title":"Vascul Pharmacol"},{"key":"4673_CR79","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.atherosclerosis.2018.09.022","volume":"278","author":"A Purroy","year":"2018","unstructured":"Purroy A, Roncal C, Orbe J, Meilhac O, Belzunce M, Zalba G et al (2018) Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification. Atherosclerosis 278:124\u201334. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2018.09.022","journal-title":"Atherosclerosis"},{"issue":"1\u20132","key":"4673_CR80","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000446703","volume":"53","author":"JM Ruddy","year":"2016","unstructured":"Ruddy JM, Ikonomidis JS, Jones JA (2016) Multidimensional contribution of matrix metalloproteinases to atherosclerotic plaque vulnerability: multiple mechanisms of inhibition to promote stability. J Vasc Res 53(1\u20132):1\u201316. https:\/\/doi.org\/10.1159\/000446703","journal-title":"J Vasc Res"},{"issue":"8","key":"4673_CR81","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.tcm.2007.09.001","volume":"17","author":"AC Newby","year":"2007","unstructured":"Newby AC (2007) Metalloproteinases and vulnerable atherosclerotic plaques. Trends Cardiovasc Med 17(8):253\u20138. https:\/\/doi.org\/10.1016\/j.tcm.2007.09.001","journal-title":"Trends Cardiovasc Med"},{"issue":"2","key":"4673_CR82","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.atherosclerosis.2011.02.026","volume":"216","author":"V Bhaskar","year":"2011","unstructured":"Bhaskar V, Yin J, Mirza AM, Phan D, Vanegas S, Issafras H et al (2011) Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice. Atherosclerosis 216(2):313\u201320. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2011.02.026","journal-title":"Atherosclerosis"},{"issue":"10","key":"4673_CR83","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1093\/ibd\/izab032","volume":"27","author":"S Verstockt","year":"2021","unstructured":"Verstockt S, Verstockt B, Machiels K, Vancamelbeke M, Ferrante M, Cleynen I et al (2021) Oncostatin M is a biomarker of diagnosis, worse disease prognosis, and therapeutic nonresponse in inflammatory bowel disease. Inflamm Bowel Dis 27(10):1564\u201375. https:\/\/doi.org\/10.1093\/ibd\/izab032","journal-title":"Inflamm Bowel Dis"},{"key":"4673_CR84","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.clinbiochem.2021.11.011","volume":"100","author":"Y Cao","year":"2022","unstructured":"Cao Y, Dai Y, Zhang L, Wang D, Yu Q, Hu W et al (2022) Serum oncostatin M is a potential biomarker of disease activity and infliximab response in inflammatory bowel disease measured by chemiluminescence immunoassay. Clin Biochem 100:35\u201341. https:\/\/doi.org\/10.1016\/j.clinbiochem.2021.11.011","journal-title":"Clin Biochem"},{"issue":"1","key":"4673_CR85","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1038\/s41598-022-05208-9","volume":"12","author":"A Guo","year":"2022","unstructured":"Guo A, Ross C, Chande N, Gregor J, Ponich T, Khanna R et al (2022) High oncostatin M predicts lack of clinical remission for patients with inflammatory bowel disease on tumor necrosis factor alpha antagonists. Sci Rep 12(1):1185. https:\/\/doi.org\/10.1038\/s41598-022-05208-9","journal-title":"Sci Rep"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-023-04673-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-023-04673-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-023-04673-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T09:07:05Z","timestamp":1697447225000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-023-04673-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":85,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["4673"],"URL":"https:\/\/doi.org\/10.1007\/s11010-023-04673-8","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]},"assertion":[{"value":"9 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors have read the manuscript and\ndeclare no conflict of interest. No writing assistance was utilized in\nthe production of this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All the authors have read the manuscript and consented for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}