{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T22:14:05Z","timestamp":1779315245788,"version":"3.51.4"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"European Union\u2019s Horizon 2020 research and innovation programme","award":["777204"],"award-info":[{"award-number":["777204"]}]},{"DOI":"10.13039\/501100004564","name":"Ministry of Education, Science and Technological Development of the Republic of Serbia","doi-asserted-by":"crossref","award":["451-03-9\/2021-14\/200378"],"award-info":[{"award-number":["451-03-9\/2021-14\/200378"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1007\/s11010-023-04690-7","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T02:02:56Z","timestamp":1680228176000},"page":"2645-2656","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sacubitril\/valsartan reverses cardiac structure and function in experimental model of hypertension-induced hypertrophic cardiomyopathy"],"prefix":"10.1007","volume":"478","author":[{"given":"Jovana","family":"Jeremic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Govoruskina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovana","family":"Bradic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isidora","family":"Milosavljevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Srejovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Zivkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevena","family":"Jeremic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Nikolic Turnic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Tanaskovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefani","family":"Bolevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Jakovljevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Bolevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko N.","family":"Zivanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nduka","family":"Okwose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragana","family":"Seklic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevena","family":"Milivojevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelena","family":"Grujic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lazar","family":"Velicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"MacGowan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Djordje G.","family":"Jakovljevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nenad","family":"Filipovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"4690_CR1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-020-01797-3","author":"M Bijani","year":"2020","unstructured":"Bijani M, Parvizi S, Dehghan A, Sedigh-Rahimabadi M, Rostami-chijan M, Kazemi M et al (2020) Investigating the prevalence of hypertension and its associated risk factors in a population-based study: Fasa PERSIAN COHORT data. BMC Cardiovasc Disord. https:\/\/doi.org\/10.1186\/s12872-020-01797-3","journal-title":"BMC Cardiovasc Disord"},{"key":"4690_CR2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/s41581-019-0244-2","volume":"16","author":"KT Mills","year":"2020","unstructured":"Mills KT, Stefanescu A, He J (2020) The global epidemiology of hypertension. Nat Rev Nephrol 16:223\u2013237. https:\/\/doi.org\/10.1038\/s41581-019-0244-2","journal-title":"Nat Rev Nephrol"},{"issue":"2","key":"4690_CR3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.5494\/wjh.v5.i2.41","volume":"5","author":"K Kuroda","year":"2015","unstructured":"Kuroda K, Kato TS, Amano A (2015) Hypertensive cardiomyopathy: a clinical approach and literature review. World J Hypertens 5(2):41\u201352. https:\/\/doi.org\/10.5494\/wjh.v5.i2.41","journal-title":"World J Hypertens"},{"key":"4690_CR4","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1161\/CIRCULATIONAHA.108.845792","volume":"123","author":"MH Drazner","year":"2011","unstructured":"Drazner MH (2011) The progression of hypertensive heart disease. Circulation 123:327\u2013334. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.108.845792","journal-title":"Circulation"},{"key":"4690_CR5","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1161\/CIRCULATIONAHA.113.001878","volume":"128","author":"JS Burchfield","year":"2013","unstructured":"Burchfield JS, Xie M, Hill JA (2013) Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation 128:388\u2013400. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.113.001878","journal-title":"Circulation"},{"key":"4690_CR6","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.hfc.2011.08.011","volume":"8","author":"JB Strait","year":"2012","unstructured":"Strait JB, Lakatta EG (2012) Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail Clin 8:143\u2013164. https:\/\/doi.org\/10.1016\/j.hfc.2011.08.011","journal-title":"Heart Fail Clin"},{"key":"4690_CR7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1093\/ndt\/gfi237","volume":"21","author":"C Cuspidi","year":"2006","unstructured":"Cuspidi C, Ciulla M, Zanchetti A (2006) Hypertensive myocardial fibrosis. Nephrol Dial Transplant 21:20\u201323. https:\/\/doi.org\/10.1093\/ndt\/gfi237","journal-title":"Nephrol Dial Transplant"},{"key":"4690_CR8","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1161\/CIRCULATIONAHA.114.013748","volume":"131","author":"M Packer","year":"2015","unstructured":"Packer M, McMurray JJV, Desai AS, Gong J, Lefkowitz MP, Rizkala AR et al (2015) Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation 131:54\u201361. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.114.013748","journal-title":"Circulation"},{"issue":"8","key":"4690_CR9","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.3390\/biomedicines10081844","volume":"10","author":"F Simko","year":"2022","unstructured":"Simko F, Baka T, Stanko P, Repova K, Krajcirovicova K, Aziriova S et al (2022) Sacubitril\/valsartan and ivabradine attenuate left ventricular remodelling and dysfunction in spontaneously hypertensive rats: different interactions with the renin-angiotensin-aldosterone system. Biomedicines 10(8):1844. https:\/\/doi.org\/10.3390\/biomedicines10081844","journal-title":"Biomedicines"},{"issue":"12","key":"4690_CR10","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1093\/ajh\/hpv015","volume":"28","author":"H Kusaka","year":"2015","unstructured":"Kusaka H, Sueta D, Koibuchi N, Hasegawa Y, Nakagawa T, Lin B et al (2015) LCZ696, angiotensin II receptor-neprilysin inhibitor, ameliorates high-salt-induced hypertension and cardiovascular injury more than valsartan alone. Am J Hypertens 28(12):1409\u20131417. https:\/\/doi.org\/10.1093\/ajh\/hpv015","journal-title":"Am J Hypertens"},{"issue":"5","key":"4690_CR11","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1097\/FJC.0000000000000662","volume":"73","author":"G Hamano","year":"2019","unstructured":"Hamano G, Yamamoto K, Takami Y, Takeshita H, Shimosato T, Moritani T et al (2019) Effects of low-dose sacubitril\/valsartan on different stages of cardiac hypertrophy in salt-loaded hypertensive rats. J Cardiovasc Pharmacol 73(5):282\u2013289. https:\/\/doi.org\/10.1097\/FJC.0000000000000662","journal-title":"J Cardiovasc Pharmacol"},{"issue":"6","key":"4690_CR12","doi-asserted-by":"publisher","first-page":"376","DOI":"10.14740\/cr1137","volume":"11","author":"K Tashiro","year":"2020","unstructured":"Tashiro K, Kuwano T, Ideishi A, Morita H, Idemoto Y, Goto M et al (2020) Sacubitril\/valsartan inhibits cardiomyocyte hypertrophy in angiotensin II-induced hypertensive mice independent of a blood pressure-lowering effect. Cardiol Res 11(6):376\u2013385. https:\/\/doi.org\/10.14740\/cr1137","journal-title":"Cardiol Res"},{"key":"4690_CR13","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1177\/1753944718784536","volume":"12","author":"S Yandrapalli","year":"2018","unstructured":"Yandrapalli S, Khan MH, Rochlani Y, Aronow WS (2018) Sacubitril\/valsartan in cardiovascular disease: evidence to date and place in therapy. Ther Adv Cardiovasc Dis 12:217\u2013231. https:\/\/doi.org\/10.1177\/1753944718784536","journal-title":"Ther Adv Cardiovasc Dis"},{"key":"4690_CR14","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1016\/s0735-1097(99)00436-2","volume":"34","author":"II Joffe","year":"1999","unstructured":"Joffe II, Travers KE, Perreault-Micale CL, Hampton T, Katz SE, Morgan JP et al (1999) Abnormal cardiac function in the streptozotocin-induced, non-insulin- dependent diabetic rat: Noninvasive assessment with doppler echocardiography and contribution of the nitric oxide pathway. J Am Coll Cardiol 34:2111\u20132119. https:\/\/doi.org\/10.1016\/s0735-1097(99)00436-2","journal-title":"J Am Coll Cardiol"},{"key":"4690_CR15","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1038\/ajh.2008.301","volume":"21","author":"M Feng","year":"2008","unstructured":"Feng M, Whitesall S, Zhang Y, Beibel M, D\u2019Alecy L, DiPetrillo K (2008) Validation of volume-pressure recording tail-cuff blood pressure measurements. Am J Hypertens 21:1288\u20131291. https:\/\/doi.org\/10.1038\/ajh.2008.301","journal-title":"Am J Hypertens"},{"key":"4690_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20010006","author":"V Jakoviljevic","year":"2019","unstructured":"Jakoviljevic V, Milic P, Bradic J, Jeremic J, Zivkovic V, Srejovic I et al (2019) Standardized aronia melanocarpa extract as novel supplement against metabolic syndrome: a rat model. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms20010006","journal-title":"Int J Mol Sci"},{"key":"4690_CR17","first-page":"496","volume":"25","author":"SH Leng","year":"2004","unstructured":"Leng SH, Lu FE, Xu LJ (2004) Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacol Sin 25:496\u2013502","journal-title":"Acta Pharmacol Sin"},{"key":"4690_CR18","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","volume":"55","author":"SA Bustin","year":"2009","unstructured":"Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M et al (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:611\u2013622. https:\/\/doi.org\/10.1373\/clinchem.2008.112797","journal-title":"Clin Chem"},{"key":"4690_CR19","doi-asserted-by":"publisher","first-page":"5245","DOI":"10.1158\/0008-5472.CAN-04-0496","volume":"64","author":"CL Andersen","year":"2004","unstructured":"Andersen CL, Jensen JL, \u00d8rntoft TF (2004) Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res 64:5245\u20135250. https:\/\/doi.org\/10.1158\/0008-5472.CAN-04-0496","journal-title":"Cancer Res"},{"key":"4690_CR20","doi-asserted-by":"publisher","first-page":"515","DOI":"10.4149\/gpb_2018004","volume":"37","author":"IM Stojic","year":"2018","unstructured":"Stojic IM, Jakovljevic VL, Zivkovic VI, Srejovic IM, Nikolic TR, Jeremic JN et al (2018) The perfusion of cisplatin and cisplatin structural analogues through the isolated rat heart: the effects on coronary flow and cardiodynamic parameters. Gen Physiol Biophys 37:515\u2013525. https:\/\/doi.org\/10.4149\/gpb_2018004","journal-title":"Gen Physiol Biophys"},{"key":"4690_CR21","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25:402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods"},{"key":"4690_CR22","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.hfc.2019.09.001","volume":"16","author":"KE Di Palo","year":"2020","unstructured":"Di Palo KE, Barone NJ (2020) Hypertension and heart failure: prevention, targets, and treatment. Heart Fail Clin 16:99\u2013106. https:\/\/doi.org\/10.1016\/j.hfc.2019.09.001","journal-title":"Heart Fail Clin"},{"key":"4690_CR23","doi-asserted-by":"publisher","first-page":"62","DOI":"10.15420\/usc.2017:17:1","volume":"11","author":"A Bindra","year":"2017","unstructured":"Bindra A, Hall SA (2017) New drugs for the treatment of heart failure. US Cardiol Rev 11:62\u201366","journal-title":"US Cardiol Rev"},{"key":"4690_CR24","doi-asserted-by":"publisher","DOI":"10.1111\/1755-5922.12435","author":"P Martens","year":"2018","unstructured":"Martens P, Beli\u00ebn H, Dupont M, Vandervoort P, Mullens W (2018) The reverse remodeling response to sacubitril\/valsartan therapy in heart failure with reduced ejection fraction. Cardiovasc Ther. https:\/\/doi.org\/10.1111\/1755-5922.12435","journal-title":"Cardiovasc Ther"},{"key":"4690_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2020.100656","author":"M Landolfo","year":"2020","unstructured":"Landolfo M, Piani F, Esposti DD, Cosentino E, Bacchelli S, Dormi A et al (2020) Effects of sacubitril valsartan on clinical and echocardiographic parameters of outpatients with heart failure and reduced ejection fraction. IJC Hear Vasc. https:\/\/doi.org\/10.1016\/j.ijcha.2020.100656","journal-title":"IJC Hear Vasc"},{"key":"4690_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41540-017-0013-4","author":"O Iborra-Egea","year":"2017","unstructured":"Iborra-Egea O, G\u00e1lvez-Mont\u00f3n C, Roura S, Perea-Gil I, Prat-Vidal C, Soler-Botija C et al (2017) Mechanisms of action of sacubitril\/valsartan on cardiac remodeling: a systems biology approach. NPJ Syst Biol Appl. https:\/\/doi.org\/10.1038\/s41540-017-0013-4","journal-title":"NPJ Syst Biol Appl"},{"issue":"7","key":"4690_CR27","doi-asserted-by":"publisher","first-page":"517","DOI":"10.4330\/wjc.v6.i7.517","volume":"6","author":"CV Rizos","year":"2014","unstructured":"Rizos CV, Elisaf MS (2014) Antihypertensive drugs and glucose metabolism. World J Cardiol 6(7):517\u2013530. https:\/\/doi.org\/10.4330\/wjc.v6.i7.517","journal-title":"World J Cardiol"},{"issue":"4","key":"4690_CR28","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.amjmed.2005.09.010","volume":"119","author":"J Garc\u00eda-Puig","year":"2006","unstructured":"Garc\u00eda-Puig J, Ruilope LM, Luque M, Fern\u00e1ndez J, Ortega R, Dal-R\u00e9 R, AVANT Study Group Investigators (2006) Glucose metabolism in patients with essential hypertension. Am J Med 119(4):318\u2013326. https:\/\/doi.org\/10.1016\/j.amjmed.2005.09.010","journal-title":"Am J Med"},{"issue":"4","key":"4690_CR29","doi-asserted-by":"publisher","first-page":"e010926","DOI":"10.1161\/JAHA.118.010926","volume":"8","author":"J Li","year":"2019","unstructured":"Li J, Kemp BA, Howell NL, Massey J, Mi\u0144czuk K, Huang Q et al (2019) Metabolic changes in spontaneously hypertensive rat hearts precede cardiac dysfunction and left ventricular hypertrophy. J Am Heart Assoc 8(4):e010926. https:\/\/doi.org\/10.1161\/JAHA.118.010926","journal-title":"J Am Heart Assoc"},{"issue":"19","key":"4690_CR30","doi-asserted-by":"publisher","first-page":"3032","DOI":"10.3390\/cells11193032","volume":"11","author":"TK Bednarski","year":"2022","unstructured":"Bednarski TK, Duda MK, Dobrzyn P (2022) Alterations of lipid metabolism in the heart in spontaneously hypertensive rats precedes left ventricular hypertrophy and cardiac dysfunction. Cells 11(19):3032. https:\/\/doi.org\/10.3390\/cells11193032","journal-title":"Cells"},{"key":"4690_CR31","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/hr.2010.264","volume":"34","author":"R Rodrigo","year":"2011","unstructured":"Rodrigo R, Gonz\u00e1lez J, Paoletto F (2011) The role of oxidative stress in the pathophysiology of hypertension. Hypertens Res 34:431\u2013440. https:\/\/doi.org\/10.1038\/hr.2010.264","journal-title":"Hypertens Res"},{"issue":"2","key":"4690_CR32","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1161\/01.hyp.0000050963.1640","volume":"41","author":"JL Cracowski","year":"2003","unstructured":"Cracowski JL, Baguet JP, Ormezzano O, Bessard J, Stanke-Labesque F, Bessard G et al (2003) Lipid peroxidation is not increased in patients with untreated mild-to-moderate hypertension. Hypertension 41(2):286\u2013288. https:\/\/doi.org\/10.1161\/01.hyp.0000050963.1640","journal-title":"Hypertension"},{"key":"4690_CR33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116007","author":"Y Nojima","year":"2015","unstructured":"Nojima Y, Ito K, Ono H, Nakazato T, Bono H, Yokoyama T et al (2015) Superoxide dismutases, SOD1 and SOD2, play a distinct role in the fat body during pupation in silkworm Bombyx mori. PLoS ONE. https:\/\/doi.org\/10.1371\/journal.pone.0116007","journal-title":"PLoS ONE"},{"key":"4690_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/antiox9100948","volume":"9","author":"M \u015aciskalska","year":"2020","unstructured":"\u015aciskalska M, O\u0142dakowska M, Marek G, Milnerowicz H (2020) Changes in the activity and concentration of superoxide dismutase isoenzymes (Cu\/zn sod, mnsod) in the blood of healthy subjects and patients with acute pancreatitis. Antioxidants 9:1\u201316. https:\/\/doi.org\/10.3390\/antiox9100948","journal-title":"Antioxidants"},{"key":"4690_CR35","doi-asserted-by":"publisher","first-page":"513","DOI":"10.3727\/096368916X694265","volume":"26","author":"WL Tseng","year":"2017","unstructured":"Tseng WL, Chou SJ, Chiang HC, Wang ML, Chien CS, Chen KH et al (2017) Imbalanced production of reactive oxygen species and mitochondrial antioxidant SOD2 in fabry disease-specific human induced pluripotent stem cell-differentiated vascular endothelial cells. Cell Transplant 26:513\u2013527. https:\/\/doi.org\/10.3727\/096368916X694265","journal-title":"Cell Transplant"},{"key":"4690_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108954","author":"CC Yang","year":"2019","unstructured":"Yang CC, Chen YT, Chen CH, Li YC, Shao PL, Huang TH et al (2019) The therapeutic impact of entresto on protecting against cardiorenal syndrome-associated renal damage in rats on high protein diet. Biomed Pharmacother. https:\/\/doi.org\/10.1016\/j.biopha.2019.108954","journal-title":"Biomed Pharmacother"},{"key":"4690_CR37","first-page":"2290","volume":"10","author":"HI Lu","year":"2018","unstructured":"Lu HI, Tong MS, Chen KH, Lee FY, Chiang JY, Chung SY et al (2018) Entresto therapy effectively protects heart and lung against transverse aortic constriction induced cardiopulmonary syndrome injury in rat. Am J Transl Res 10:2290\u20132305","journal-title":"Am J Transl Res"},{"key":"4690_CR38","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.ahj.2009.09.006","volume":"158","author":"CJ McLeod","year":"2009","unstructured":"McLeod CJ, Bos JM, Theis JL, Edwards WD, Gersh BJ, Ommen SR et al (2009) Histologic characterization of hypertrophic cardiomyopathy with and without myofilament mutations. Am Heart J 158:799\u2013805. https:\/\/doi.org\/10.1016\/j.ahj.2009.09.006","journal-title":"Am Heart J"},{"issue":"4","key":"4690_CR39","doi-asserted-by":"publisher","first-page":"e005565","DOI":"10.1161\/CIRCHEARTFAILURE.118.005565","volume":"12","author":"RM Burke","year":"2019","unstructured":"Burke RM, Lighthouse JK, Mickelsen DM, Small EM (2019) Sacubitril\/valsartan decreases cardiac fibrosis in left ventricle pressure overload by restoring pkg signaling in cardiac fibroblasts. Circ Heart Fail 12(4):e005565. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.118.005565","journal-title":"Circ Heart Fail"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-023-04690-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-023-04690-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-023-04690-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T03:11:57Z","timestamp":1699240317000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-023-04690-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["4690"],"URL":"https:\/\/doi.org\/10.1007\/s11010-023-04690-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-1956344\/v1","asserted-by":"object"}]},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,30]]},"assertion":[{"value":"12 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}},{"value":"The protocol for this study was approved by the ethical committee for experimental animals\u2019 well-being of the Faculty of Medical Sciences, University of Kragujevac, Serbia. All animals used in this study were sourced from the Institute for Medical Research, University of Belgrade, and written informed consent was obtained prior to use of the animals.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"No human data were used in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for human and animal participants"}}]}}