{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:12:40Z","timestamp":1785453160489,"version":"3.56.0"},"reference-count":102,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Shujin Guo","award":["Grant 81700044"],"award-info":[{"award-number":["Grant 81700044"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s11010-024-05065-2","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T13:02:01Z","timestamp":1720616521000},"page":"841-853","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pathogenesis of cardiovascular diseases: effects of mitochondrial CF6 on endothelial cell function"],"prefix":"10.1007","volume":"480","author":[{"given":"Yingying","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youren","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengwei","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengchun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiumei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Shuai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyou","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"5065_CR1","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.jacc.2023.08.007","volume":"82","author":"CJ Lavie","year":"2023","unstructured":"Lavie CJ, German CA, Sanchis-Gomar F (2023) Reducing mortality and cardiovascular disease: stepping up our game. J Am Coll Cardiol 82:1495\u20131498","journal-title":"J Am Coll Cardiol"},{"key":"5065_CR2","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/CIRCRESAHA.117.308903","volume":"121","author":"P Joseph","year":"2017","unstructured":"Joseph P, Leong D, McKee M, Anand SS, Schwalm J-D, Teo K et al (2017) Reducing the global burden of cardiovascular disease, part 1: the epidemiology and risk factors. Circ Res 121:677\u2013694","journal-title":"Circ Res"},{"key":"5065_CR3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1161\/CIR.0000000000000366","volume":"133","author":"D Mozaffarian","year":"2016","unstructured":"Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Writing Group Members et al (2016) Executive summary: heart disease and stroke statistics--2016 update: a report from the American Heart Association. Circulation 133:447\u2013454","journal-title":"Circulation"},{"key":"5065_CR4","doi-asserted-by":"crossref","first-page":"1278166","DOI":"10.3389\/fcell.2023.1278166","volume":"11","author":"JD Allbritton-King","year":"2023","unstructured":"Allbritton-King JD, Garc\u00eda-Carde\u00f1a G (2023) Endothelial cell dysfunction in cardiac disease: driver or consequence? Front Cell Dev Biol 11:1278166","journal-title":"Front Cell Dev Biol"},{"key":"5065_CR5","doi-asserted-by":"crossref","first-page":"e23012","DOI":"10.1096\/fj.202300393R","volume":"37","author":"X Wei","year":"2023","unstructured":"Wei X, Zhang M, Huang S, Lan X, Zheng J, Luo H et al (2023) Hyperuricemia: a key contributor to endothelial dysfunction in cardiovascular diseases. FASEB J 37:e23012","journal-title":"FASEB J"},{"key":"5065_CR6","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1161\/hc5001.100832","volume":"104","author":"T Osanai","year":"2001","unstructured":"Osanai T, Okada S, Sirato K, Nakano T, Saitoh M, Magota K et al (2001) Mitochondrial coupling factor 6 is present on the surface of human vascular endothelial cells and is released by shear stress. Circulation 104:3132\u20133136","journal-title":"Circulation"},{"key":"5065_CR7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.cardiores.2004.01.031","volume":"62","author":"S Sasaki","year":"2004","unstructured":"Sasaki S (2004) Tumor necrosis factor $alpha; as an endogenous stimulator for circulating coupling factor 6. Cardiovasc Res 62:578\u2013586","journal-title":"Cardiovasc Res"},{"key":"5065_CR8","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.cardiores.2005.02.022","volume":"67","author":"H Tomita","year":"2005","unstructured":"Tomita H, Osanai T, Toki T, Sasaki S, Maeda N, Murakami R et al (2005) Troglitazone and 15-deoxy-\u0394-prostaglandin J inhibit shear-induced coupling factor 6 release in endothelial cells. Cardiovasc Res 67:134\u2013141","journal-title":"Cardiovasc Res"},{"key":"5065_CR9","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1172\/JCI11076","volume":"108","author":"T Osanai","year":"2001","unstructured":"Osanai T, Tanaka M, Kamada T, Nakano T, Takahashi K, Okada S et al (2001) Mitochondrial coupling factor 6 as a potent endogenous vasoconstrictor. J Clin Invest 108:1023\u20131030","journal-title":"J Clin Invest"},{"key":"5065_CR10","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1126\/science.1990440","volume":"251","author":"MI Cybulsky","year":"1991","unstructured":"Cybulsky MI, Gimbrone MA (1991) Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251:788\u2013791","journal-title":"Science"},{"issue":"12","key":"5065_CR11","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1097\/00004872-200312000-00021","volume":"21","author":"T Osanai","year":"2003","unstructured":"Osanai T, Sasaki S, Kamada T, Fujiwara N, Nakano T, Tomita H et al (2003) Circulating coupling factor 6 in human hypertension: role of reactive oxygen species. J Hypertens 21(12):2323\u20132328","journal-title":"J Hypertens"},{"key":"5065_CR12","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1291\/hypres.27.717","volume":"27","author":"W Hui Ding","year":"2004","unstructured":"Hui Ding W, Yun Chu S, Feng Jiang H, Yong Cai D, Zheng Pang Y, Shu Tang C et al (2004) Plasma mitochondrial coupling factor 6 in patients with acute myocardial infarction. Hypertens Res 27:717\u2013722","journal-title":"Hypertens Res"},{"key":"5065_CR13","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1046\/j.1523-1755.2003.00334.x","volume":"64","author":"T Osanai","year":"2003","unstructured":"Osanai T, Nakamura M, Sasaki S, Tomita H, Saitoh M, Osawa H et al (2003) Plasma concentration of coupling factor 6 and cardiovascular events in patients with end-stage renal disease. Kidney Int 64:2291\u20132297","journal-title":"Kidney Int"},{"key":"5065_CR14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3109\/07853890903451781","volume":"42","author":"T Osanai","year":"2010","unstructured":"Osanai T, Fujiwara N, Sasaki S, Metoki N, Saitoh G, Tomita H et al (2010) Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine. Ann Med 42:79\u201386","journal-title":"Ann Med"},{"key":"5065_CR15","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.3892\/etm.2021.10619","volume":"22","author":"W Song","year":"2021","unstructured":"Song W, Shi X, Liu K, Li R, Niu L, Su L et al (2021) Detection of mitochondrial coupling factor 6 in placental tissues from preeclamptic pregnancies and its influence on biological behavior of trophoblast cells. Exp Ther Med 22:1185","journal-title":"Exp Ther Med"},{"key":"5065_CR16","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.amjms.2016.08.002","volume":"352","author":"N Li","year":"2016","unstructured":"Li N, Yin J, Cai W, Liu J, Zhang N, Yan S et al (2016) Coupling factor 6 is upregulated in monocrotaline-induced pulmonary arterial hypertension in rats. Am J Med Sci 352:631\u2013636","journal-title":"Am J Med Sci"},{"key":"5065_CR17","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s11302-016-9508-5","volume":"12","author":"J Aho","year":"2016","unstructured":"Aho J, Helenius M, Vattulainen-Collanus S, Alastalo T-P, Koskenvuo J (2016) Extracellular ATP protects endothelial cells against DNA damage. Purinergic Signal 12:575\u2013581","journal-title":"Purinergic Signal"},{"key":"5065_CR18","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1111\/bph.16050","volume":"180","author":"M Jiang","year":"2023","unstructured":"Jiang M, Zhang Y-X, Bu W-J, Li P, Chen J-H, Cao M et al (2023) Piezo1 channel activation stimulates ATP production through enhancing mitochondrial respiration and glycolysis in vascular endothelial cells. Br J Pharmacol 180:1862\u20131877","journal-title":"Br J Pharmacol"},{"key":"5065_CR19","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.molcel.2023.04.029","volume":"83","author":"Y Lai","year":"2023","unstructured":"Lai Y, Zhang Y, Zhou S, Xu J, Du Z, Feng Z et al (2023) Structure of the human ATP synthase. Mol Cell 83:2137-2147.e4","journal-title":"Mol Cell"},{"key":"5065_CR20","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00018-022-04153-0","volume":"79","author":"AV Vlasov","year":"2022","unstructured":"Vlasov AV, Osipov SD, Bondarev NA, Uversky VN, Borshchevskiy VI, Yanyushin MF et al (2022) ATP synthase FOF1 structure, function, and structure-based drug design. Cell Mol Life Sci 79:179","journal-title":"Cell Mol Life Sci"},{"key":"5065_CR21","doi-asserted-by":"crossref","first-page":"965620","DOI":"10.3389\/fmicb.2022.965620","volume":"13","author":"WD Frasch","year":"2022","unstructured":"Frasch WD, Bukhari ZA, Yanagisawa S (2022) F1FO ATP synthase molecular motor mechanisms. Front Microbiol 13:965620","journal-title":"Front Microbiol"},{"key":"5065_CR22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00210-009-0431-y","volume":"380","author":"T Osanai","year":"2009","unstructured":"Osanai T, Magota K, Okumura K (2009) Coupling factor 6 as a novel vasoactive and proatherogenic peptide in vascular endothelial cells. Naunyn Schmiedebergs Arch Pharmacol 380:205\u2013214","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"5065_CR23","doi-asserted-by":"crossref","first-page":"4074","DOI":"10.2174\/138161210794519219","volume":"16","author":"Y Fu","year":"2010","unstructured":"Fu Y, Zhu Y (2010) Ectopic ATP synthase in endothelial cells: a novel cardiovascular therapeutic target. Curr Pharm Des 16:4074\u20134079","journal-title":"Curr Pharm Des"},{"key":"5065_CR24","doi-asserted-by":"crossref","first-page":"12753","DOI":"10.1038\/s41598-022-16998-3","volume":"12","author":"A Gallinat","year":"2022","unstructured":"Gallinat A, Badimon L (2022) DJ-1 interacts with the ectopic ATP-synthase in endothelial cells during acute ischemia and reperfusion. Sci Rep 12:12753","journal-title":"Sci Rep"},{"issue":"46","key":"5065_CR25","first-page":"1140","volume":"2005","author":"T Osanai","year":"1979","unstructured":"Osanai T, Magota K, Tanaka M, Shimada M, Murakami R, Sasaki S et al (1979) Intracellular signaling for vasoconstrictor coupling factor 6: novel function of beta-subunit of ATP synthase as receptor. Hypertens Dallas Tex 2005(46):1140\u20131146","journal-title":"Hypertens Dallas Tex"},{"key":"5065_CR26","doi-asserted-by":"crossref","first-page":"6194","DOI":"10.1002\/jcb.26828","volume":"119","author":"T Osanai","year":"2018","unstructured":"Osanai T, Tanaka M, Mikami K, Kitajima M, Magota K, Tomita H et al (2018) Mitochondrial inhibitory factor protein 1 attenuates coupling factor 6-induced aging signal. J Cell Biochem 119:6194\u20136203","journal-title":"J Cell Biochem"},{"key":"5065_CR27","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1002\/jcb.25461","volume":"117","author":"M Kawai","year":"2016","unstructured":"Kawai M, Osanai T, Tanaka M, Magota K, Tomita H, Okumura K (2016) Mitochondrial inhibitory factor protein 1 functions as an endogenous inhibitor for coupling factor 6. J Cell Biochem 117:1680\u20131687","journal-title":"J Cell Biochem"},{"key":"5065_CR28","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3390\/biology13020070","volume":"13","author":"A Kulovic-Sissawo","year":"2024","unstructured":"Kulovic-Sissawo A, Tocantins C, Diniz MS, Weiss E, Steiner A, Tokic S et al (2024) Mitochondrial dysfunction in endothelial progenitor cells: unraveling insights from vascular endothelial cells. Biology 13:70","journal-title":"Biology"},{"key":"5065_CR29","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.mayocp.2023.05.008","volume":"99","author":"M Kou","year":"2024","unstructured":"Kou M, Wang X, Ma H, Li X, Heianza Y, Qi L (2024) Degree of risk factor control and incident cardiovascular diseases in patients with hypertension. Mayo Clin Proc 99:387\u2013399","journal-title":"Mayo Clin Proc"},{"key":"5065_CR30","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ijcard.2006.05.051","volume":"117","author":"XL Li","year":"2007","unstructured":"Li XL, Xing QC, Dong B, Gao YY, Xing SS, Pang YZ et al (2007) Plasma level of mitochondrial coupling factor 6 increases in patients with type 2 diabetes mellitus. Int J Cardiol 117:411\u2013412","journal-title":"Int J Cardiol"},{"key":"5065_CR31","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1253\/circj.71.693","volume":"71","author":"SB Chai","year":"2007","unstructured":"Chai SB, Hui YM, Li XM, Tang CS (2007) Plasma level of mitochondrial coupling factor 6 increases in patients with coronary heart disease. Circ J 71:693\u2013697","journal-title":"Circ J"},{"key":"5065_CR32","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.peptides.2006.11.006","volume":"28","author":"X Li","year":"2007","unstructured":"Li X, Xing S, Zhang L, Xing Q, Yan S, Dai H et al (2007) High glucose promotes the release and expression of novel vasoactive peptide, coupling factor 6, in human umbilical vein endothelial cells. Peptides 28:683\u2013690","journal-title":"Peptides"},{"key":"5065_CR33","doi-asserted-by":"crossref","first-page":"154766","DOI":"10.1016\/j.metabol.2021.154766","volume":"119","author":"MA Hill","year":"2021","unstructured":"Hill MA, Yang Y, Zhang L, Sun Z, Jia G, Parrish AR et al (2021) Insulin resistance, cardiovascular stiffening and cardiovascular disease. Metabolism 119:154766","journal-title":"Metabolism"},{"key":"5065_CR34","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1007\/s00125-011-2341-z","volume":"55","author":"T Osanai","year":"2012","unstructured":"Osanai T, Tanaka M, Magota K, Tomita H, Okumura K (2012) Coupling factor 6-induced activation of ecto-F1Fo complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice. Diabetologia 55:520\u2013529","journal-title":"Diabetologia"},{"key":"5065_CR35","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41581-019-0244-2","volume":"16","author":"KT Mills","year":"2020","unstructured":"Mills KT, Stefanescu A, He J (2020) The global epidemiology of hypertension. Nat Rev Nephrol 16:223\u2013237","journal-title":"Nat Rev Nephrol"},{"key":"5065_CR36","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/s41371-021-00570-z","volume":"36","author":"R Yin","year":"2022","unstructured":"Yin R, Yin L, Li L, Silva-Nash J, Tan J, Pan Z et al (2022) Hypertension in China: burdens, guidelines and policy responses: a state-of-the-art review. J Hum Hypertens 36:126\u2013134","journal-title":"J Hum Hypertens"},{"key":"5065_CR37","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1093\/eurheartj\/ehac395","volume":"44","author":"L Lauder","year":"2023","unstructured":"Lauder L, Mahfoud F, Azizi M, Bhatt DL, Ewen S, Kario K et al (2023) Hypertension management in patients with cardiovascular comorbidities. Eur Heart J 44:2066\u20132077","journal-title":"Eur Heart J"},{"issue":"80","key":"5065_CR38","first-page":"22","volume":"2023","author":"MM Santisteban","year":"1979","unstructured":"Santisteban MM, Iadecola C, Carnevale D (1979) Hypertension, neurovascular dysfunction, and cognitive impairment. Hypertens Dallas Tex 2023(80):22\u201334","journal-title":"Hypertens Dallas Tex"},{"key":"5065_CR39","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1097\/HJH.0b013e32832d4b05","volume":"27","author":"T Osanai","year":"2009","unstructured":"Osanai T, Tomita H, Yamada M, Tanaka M, Ashitate T, Echizen T et al (2009) Coupling factor 6-induced prostacyclin inhibition is enhanced in vascular smooth muscle cells from spontaneously hypertensive rats. J Hypertens 27:1823\u20131828","journal-title":"J Hypertens"},{"key":"5065_CR40","first-page":"2617","volume":"12","author":"MS Karthikesh","year":"2022","unstructured":"Karthikesh MS, Wu S, Singh R, Paulus Y, Wang X, Yang X (2022) Effect of photo-mediated ultrasound therapy on nitric oxide and prostacyclin from endothelial cells. Appl Sci Basel Switz 12:2617","journal-title":"Appl Sci Basel Switz"},{"key":"5065_CR41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.intimp.2004.10.016","volume":"5","author":"EM Zardi","year":"2005","unstructured":"Zardi EM, Zardi DM, Cacciapaglia F, Dobrina A, Amoroso A, Picardi A et al (2005) Endothelial dysfunction and activation as an expression of disease: role of prostacyclin analogs. Int Immunopharmacol 5:437\u2013459","journal-title":"Int Immunopharmacol"},{"key":"5065_CR42","doi-asserted-by":"crossref","first-page":"31778","DOI":"10.1074\/jbc.273.48.31778","volume":"273","author":"T Osanai","year":"1998","unstructured":"Osanai T, Kamada T, Fujiwara N, Katoh T, Takahashi K, Kimura M et al (1998) A novel inhibitory effect on prostacyclin synthesis of coupling factor 6 extracted from the heart of spontaneously hypertensive rats. J Biol Chem 273:31778\u201331783","journal-title":"J Biol Chem"},{"key":"5065_CR43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.atherosclerosis.2007.12.010","volume":"200","author":"A Kumagai","year":"2008","unstructured":"Kumagai A, Osanai T, Katoh C, Tanaka M, Tomita H, Morimoto T et al (2008) Coupling factor 6 downregulates platelet endothelial cell adhesion molecule-1 via c-Src activation and acts as a proatherogenic molecule. Atherosclerosis 200:45\u201350","journal-title":"Atherosclerosis"},{"key":"5065_CR44","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/cvr\/cvn356","volume":"81","author":"T Osanai","year":"2008","unstructured":"Osanai T, Tomita H, Kushibiki M, Yamada M, Tanaka M, Ashitate T et al (2008) Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells. Cardiovasc Res 81:780\u2013787","journal-title":"Cardiovasc Res"},{"key":"5065_CR45","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1097\/HJH.0b013e32833dfcbe","volume":"28","author":"T Ashitate","year":"2010","unstructured":"Ashitate T, Osanai T, Tanaka M, Magota K, Echizen T, Izumiyama K et al (2010) Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice. J Hypertens 28:2243\u20132251","journal-title":"J Hypertens"},{"key":"5065_CR46","first-page":"4629189","volume":"2020","author":"Y Chen","year":"2020","unstructured":"Chen Y, Li S, Guo Y, Yu H, Bao Y, Xin X et al (2020) Astaxanthin attenuates hypertensive vascular remodeling by protecting vascular smooth muscle cells from oxidative stress-induced mitochondrial dysfunction. Oxid Med Cell Longev 2020:4629189","journal-title":"Oxid Med Cell Longev"},{"key":"5065_CR47","doi-asserted-by":"crossref","first-page":"103386","DOI":"10.1016\/j.ebiom.2021.103386","volume":"67","author":"Z Cai","year":"2021","unstructured":"Cai Z, Wang Z, Yuan R, Cui M, Lao Y, Wang Y et al (2021) Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of \u03b2-catenin and regulation of its stability. EBioMedicine 67:103386","journal-title":"EBioMedicine"},{"key":"5065_CR48","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/s41440-022-01063-3","volume":"46","author":"D Piskorz","year":"2023","unstructured":"Piskorz D, Keller L, Citta L, Mata L, Tissera G, Bongarzoni L et al (2023) Diastolic dysfunction, hypertrophy and hypertension ventricular-arterial uncoupling treatment. Hypertens Res 46:136\u2013143","journal-title":"Hypertens Res"},{"key":"5065_CR49","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s40292-022-00521-w","volume":"29","author":"D Piskorz","year":"2022","unstructured":"Piskorz D, Keller L, Citta L, Mata L, Citta N, Bongarzoni L et al (2022) Ventricular-arterial uncoupling and hypertension mediated diastolic dysfunction. High Blood Press Cardiovasc Prev 29:361\u2013366","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"5065_CR50","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s00059-015-4301-8","volume":"40","author":"T He","year":"2015","unstructured":"He T, Guan A, Shi Y, Ge Z, Dai H (2015) Mitochondrial coupling factor 6 upregulation in hypertension-induced cardiac hypertrophy. Herz 40:783\u2013787","journal-title":"Herz"},{"key":"5065_CR51","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/hr.2011.232","volume":"35","author":"K Izumiyama","year":"2012","unstructured":"Izumiyama K, Osanai T, Sagara S, Yamamoto Y, Itoh T, Sukekawa T et al (2012) Estrogen attenuates coupling factor 6-induced salt-sensitive hypertension and cardiac systolic dysfunction in mice. Hypertens Res 35:539\u2013546","journal-title":"Hypertens Res"},{"key":"5065_CR52","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.2337\/diabetes.52.6.1319","volume":"52","author":"K Bouzakri","year":"2003","unstructured":"Bouzakri K, Roques M, Gual P, Espinosa S, Guebre-Egziabher F, Riou J-P et al (2003) Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes. Diabetes 52:1319\u20131325","journal-title":"Diabetes"},{"key":"5065_CR53","doi-asserted-by":"crossref","first-page":"45304","DOI":"10.1074\/jbc.C400186200","volume":"279","author":"Y Li","year":"2004","unstructured":"Li Y, Soos TJ, Li X, Wu J, Degennaro M, Sun X et al (2004) Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). J Biol Chem 279:45304\u201345307","journal-title":"J Biol Chem"},{"key":"5065_CR54","first-page":"e563","volume":"140","author":"DK Arnett","year":"2019","unstructured":"Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Goldberger ZD, Hahn EJ et al (2019) 2019 ACC\/AHA guideline on the primary prevention of cardiovascular disease: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 140:e563\u2013e595","journal-title":"Circulation"},{"key":"5065_CR55","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/s41569-023-00879-x","volume":"20","author":"MKS Lee","year":"2023","unstructured":"Lee MKS, Murphy AJ (2023) A high-salt diet promotes atherosclerosis by altering haematopoiesis. Nat Rev Cardiol 20:435\u2013436","journal-title":"Nat Rev Cardiol"},{"key":"5065_CR56","doi-asserted-by":"crossref","first-page":"C7","DOI":"10.1016\/j.jacc.2005.09.068","volume":"47","author":"E Falk","year":"2006","unstructured":"Falk E (2006) Pathogenesis of atherosclerosis. J Am Coll Cardiol 47:C7\u2013C12","journal-title":"J Am Coll Cardiol"},{"key":"5065_CR57","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1038\/nm.2538","volume":"17","author":"C Weber","year":"2011","unstructured":"Weber C, Noels H (2011) Atherosclerosis: current pathogenesis and therapeutic options. Nat Med 17:1410\u20131422","journal-title":"Nat Med"},{"key":"5065_CR58","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.3390\/ijms24032600","volume":"24","author":"K Kie\u0142bowski","year":"2023","unstructured":"Kie\u0142bowski K, Bakinowska E, Pawlik A (2023) The potential role of connexins in the pathogenesis of atherosclerosis. Int J Mol Sci 24:2600","journal-title":"Int J Mol Sci"},{"key":"5065_CR59","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s12272-021-01324-8","volume":"44","author":"F Wang","year":"2021","unstructured":"Wang F, Yu R, Wen S, Yin J, Shi Y, Hu H et al (2021) Overexpressing microRNA-203 alleviates myocardial infarction via interacting with long non-coding RNA MIAT and mitochondrial coupling factor 6. Arch Pharm Res 44:525\u2013535","journal-title":"Arch Pharm Res"},{"key":"5065_CR60","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S1078-5884(03)00385-X","volume":"26","author":"J Vane","year":"2003","unstructured":"Vane J, Corin RE (2003) Prostacyclin: a vascular mediator. Eur J Vasc Endovasc Surg 26:571\u2013578","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"5065_CR61","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/hr.2008.24","volume":"32","author":"T Echizen","year":"2009","unstructured":"Echizen T, Osanai T, Ashitate T, Yokoyama H, Shibutani S, Tanaka M et al (2009) Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells: a role of acidosis-induced c-Src activation. Hypertens Res 32:182\u2013187","journal-title":"Hypertens Res"},{"key":"5065_CR62","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.3390\/jcm9093026","volume":"9","author":"L Dowsett","year":"2020","unstructured":"Dowsett L, Higgins E, Alanazi S, Alshuwayer NA, Leiper FC, Leiper J (2020) ADMA: a key player in the relationship between vascular dysfunction and inflammation in atherosclerosis. J Clin Med 9:3026","journal-title":"J Clin Med"},{"key":"5065_CR63","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/s12872-022-02634-5","volume":"22","author":"J Tao","year":"2022","unstructured":"Tao J, Hu Y (2022) Diagnostic and prognostic significance of lncRNA SOX2-OT in patients with carotid atherosclerosis. BMC Cardiovasc Disord 22:211","journal-title":"BMC Cardiovasc Disord"},{"key":"5065_CR64","first-page":"837","volume":"8","author":"C-N Hsu","year":"2021","unstructured":"Hsu C-N, Tain Y-L (2021) Asymmetric dimethylarginine (ADMA) in pediatric renal diseases: from pathophysiological phenomenon to clinical biomarker and beyond. Child Basel Switz 8:837","journal-title":"Child Basel Switz"},{"key":"5065_CR65","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/imm.13396","volume":"164","author":"I Singh","year":"2021","unstructured":"Singh I, Kim J, Saxena N, Choi S, Islam SMT, Singh AK et al (2021) Vascular and immunopathological role of asymmetric dimethylarginine (ADMA) in experimental autoimmune encephalomyelitis. Immunology 164:602\u2013616","journal-title":"Immunology"},{"key":"5065_CR66","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/01.hjh.0000209985.66853.1e","volume":"24","author":"M Tanaka","year":"2006","unstructured":"Tanaka M, Osanai T, Murakami R, Sasaki S, Tomita H, Maeda N et al (2006) Effect of vasoconstrictor coupling factor 6 on gene expression profile in human vascular endothelial cells: enhanced release of asymmetric dimethylarginine. J Hypertens 24:489\u2013497","journal-title":"J Hypertens"},{"key":"5065_CR67","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1161\/01.RES.0000052990.68216.EF","volume":"92","author":"S Ueda","year":"2003","unstructured":"Ueda S, Kato S, Matsuoka H, Kimoto M, Okuda S, Morimatsu M et al (2003) Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase. Circ Res 92:226\u2013233","journal-title":"Circ Res"},{"key":"5065_CR68","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1080\/09537104.2020.1719055","volume":"32","author":"E Gao","year":"2021","unstructured":"Gao E, Hou J, Zhou Y, Ma J, Li T, Zhang J et al (2021) Mediation effect of platelet indices on the association of daytime nap duration with 10-year ASCVD risk. Platelets 32:82\u201389","journal-title":"Platelets"},{"key":"5065_CR69","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s40795-022-00541-8","volume":"8","author":"BB Nkambule","year":"2022","unstructured":"Nkambule BB, Mxinwa V, Nyambuya TM, Dludla PV (2022) The mean platelet volume and atherosclerotic cardiovascular-risk factors in adults with obesity: a systematic review and meta-analysis of observational studies. BMC Nutr 8:47","journal-title":"BMC Nutr"},{"key":"5065_CR70","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1038\/s41467-023-38069-5","volume":"14","author":"A Polzin","year":"2023","unstructured":"Polzin A, Dannenberg L, Benkhoff M, Barcik M, Helten C, Mourikis P et al (2023) Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction. Nat Commun 14:2404","journal-title":"Nat Commun"},{"key":"5065_CR71","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12933-018-0763-3","volume":"17","author":"R Kaur","year":"2018","unstructured":"Kaur R, Kaur M, Singh J (2018) Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies. Cardiovasc Diabetol 17:121","journal-title":"Cardiovasc Diabetol"},{"key":"5065_CR72","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.2337\/diacare.26.7.2181","volume":"26","author":"JA Colwell","year":"2003","unstructured":"Colwell JA, Nesto RW (2003) The platelet in diabetes: focus on prevention of ischemic events. Diabetes Care 26:2181\u20132188","journal-title":"Diabetes Care"},{"key":"5065_CR73","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s11239-020-02185-6","volume":"51","author":"T Osanai","year":"2021","unstructured":"Osanai T, Mikami K, Kitajima M, Urushizaka M, Tomisawa T, Hagii J et al (2021) Incidence and characteristics of spontaneous platelet macro-aggregation in acute ischemic stroke. J Thromb Thrombolysis 51:96\u2013101","journal-title":"J Thromb Thrombolysis"},{"key":"5065_CR74","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/hr.2012.231","volume":"36","author":"T Sukekawa","year":"2013","unstructured":"Sukekawa T, Osanai T, Nishizaki F, Metoki N, Hagii J, Kamada T et al (2013) Coupling factor 6 enhances the spontaneous microaggregation of platelets by decreasing cytosolic cAMP irrespective of antiplatelet therapy. Hypertens Res 36:520\u2013527","journal-title":"Hypertens Res"},{"key":"5065_CR75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijbiomac.2019.02.003","volume":"130","author":"J Yi","year":"2019","unstructured":"Yi J, Gao Z-F (2019) MicroRNA-9-5p promotes angiogenesis but inhibits apoptosis and inflammation of high glucose-induced injury in human umbilical vascular endothelial cells by targeting CXCR4. Int J Biol Macromol 130:1\u20139","journal-title":"Int J Biol Macromol"},{"key":"5065_CR76","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/hr.2014.65","volume":"37","author":"A Suzuki","year":"2014","unstructured":"Suzuki A, Osanai T, Tanaka M, Tomita H, Magota K, Okumura K (2014) Coupling factor 6 attenuates CXCR4 expression through the HIF-1\u03b1 and c-Src pathways and promotes endothelial apoptosis and inflammation. Hypertens Res 37:708\u2013715","journal-title":"Hypertens Res"},{"key":"5065_CR77","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1158\/1541-7786.MCR-07-0054","volume":"5","author":"E Matteucci","year":"2007","unstructured":"Matteucci E, Ridolfi E, Maroni P, Bendinelli P, Desiderio MA (2007) c-Src\/histone deacetylase 3 interaction is crucial for hepatocyte growth factor dependent decrease of CXCR4 expression in highly invasive breast tumor cells. Mol Cancer Res 5:833\u2013845","journal-title":"Mol Cancer Res"},{"key":"5065_CR78","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","volume":"43","author":"M Humbert","year":"2022","unstructured":"Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M et al (2022) 2022 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 43:3618\u20133731","journal-title":"Eur Heart J"},{"key":"5065_CR79","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1161\/CIRCULATIONAHA.122.058794","volume":"147","author":"E Born","year":"2023","unstructured":"Born E, Lipskaia L, Breau M, Houssaini A, Beaulieu D, Marcos E et al (2023) Eliminating senescent cells can promote pulmonary hypertension development and progression. Circulation 147:650\u2013666","journal-title":"Circulation"},{"key":"5065_CR80","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1152\/physrev.00030.2021","volume":"103","author":"A Balistrieri","year":"2023","unstructured":"Balistrieri A, Makino A, Yuan JX-J (2023) Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling. Physiol Rev 103:1827\u20131897","journal-title":"Physiol Rev"},{"key":"5065_CR81","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.55730\/1300-0144.5485","volume":"52","author":"N Li","year":"2022","unstructured":"Li N, Shi Y, Yin J, Sun L, Zhang Q, Bao S et al (2022) Impact of ATP synthase\/coupling factor 6 in hypoxic pulmonary arterial hypertension: an experimental rat model. Turk J Med Sci 52:1468\u20131477","journal-title":"Turk J Med Sci"},{"key":"5065_CR82","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12931-016-0409-5","volume":"17","author":"J Yin","year":"2016","unstructured":"Yin J, You S, Li N, Jiao S, Hu H, Xue M et al (2016) Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats. Respir Res 17:99","journal-title":"Respir Res"},{"key":"5065_CR83","doi-asserted-by":"crossref","first-page":"2101694","DOI":"10.1183\/13993003.01694-2021","volume":"60","author":"T Ogo","year":"2022","unstructured":"Ogo T, Shimokawahara H, Kinoshita H, Sakao S, Abe K, Matoba S et al (2022) Selexipag for the treatment of chronic thromboembolic pulmonary hypertension. Eur Respir J 60:2101694","journal-title":"Eur Respir J"},{"key":"5065_CR84","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/17476348.2017.1317599","volume":"11","author":"R Del Pozo","year":"2017","unstructured":"Del Pozo R, Hernandez Gonzalez I, Escribano-Subias P (2017) The prostacyclin pathway in pulmonary arterial hypertension: a clinical review. Expert Rev Respir Med 11:491\u2013503","journal-title":"Expert Rev Respir Med"},{"key":"5065_CR85","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1161\/CIRCRESAHA.116.308030","volume":"119","author":"SA Dick","year":"2016","unstructured":"Dick SA, Epelman S (2016) Chronic heart failure and inflammation: what do we really know? Circ Res 119:159\u2013176","journal-title":"Circ Res"},{"key":"5065_CR86","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvae045","author":"E Beslika","year":"2024","unstructured":"Beslika E, Leite-Moreira A, De Windt LJ, da Costa Martins P (2024) Large animal models of pressure overload-induced cardiac left ventricular hypertrophy to study remodeling of the human heart with aortic stenosis. Cardiovasc Res. https:\/\/doi.org\/10.1093\/cvr\/cvae045","journal-title":"Cardiovasc Res"},{"key":"5065_CR87","doi-asserted-by":"crossref","first-page":"794","DOI":"10.3390\/ijms25020794","volume":"25","author":"L Stoicescu","year":"2024","unstructured":"Stoicescu L, Cri\u015fan D, Morgovan C, Avram L, Ghibu S (2024) Heart failure with preserved ejection fraction: the pathophysiological mechanisms behind the clinical phenotypes and the therapeutic approach. Int J Mol Sci 25:794","journal-title":"Int J Mol Sci"},{"key":"5065_CR88","doi-asserted-by":"crossref","first-page":"e010673","DOI":"10.1161\/CIRCHEARTFAILURE.123.010673","volume":"16","author":"M Tamargo","year":"2023","unstructured":"Tamargo M, Mart\u00ednez-Legazpi P, Espinosa M\u00c1, Lyon A, M\u00e9ndez I, Guti\u00e9rrez-Iba\u00f1es E et al (2023) Increased chamber resting tone is a key determinant of left ventricular diastolic dysfunction. Circ Heart Fail 16:e010673","journal-title":"Circ Heart Fail"},{"key":"5065_CR89","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3390\/ijms25010510","volume":"25","author":"A Papamichail","year":"2023","unstructured":"Papamichail A, Kourek C, Briasoulis A, Xanthopoulos A, Tsougos E, Farmakis D et al (2023) Targeting key inflammatory mechanisms underlying heart failure: a comprehensive review. Int J Mol Sci 25:510","journal-title":"Int J Mol Sci"},{"key":"5065_CR90","doi-asserted-by":"crossref","first-page":"102163","DOI":"10.1016\/j.arr.2023.102163","volume":"93","author":"X Ye","year":"2024","unstructured":"Ye X, Wang Z, Lei W, Shen M, Tang J, Xu X et al (2024) Pentraxin 3: a promising therapeutic target for cardiovascular diseases. Ageing Res Rev 93:102163","journal-title":"Ageing Res Rev"},{"key":"5065_CR91","doi-asserted-by":"crossref","first-page":"933215","DOI":"10.3389\/fcvm.2022.933215","volume":"9","author":"Z Abassi","year":"2022","unstructured":"Abassi Z, Khoury EE, Karram T, Aronson D (2022) Edema formation in congestive heart failure and the underlying mechanisms. Front Cardiovasc Med 9:933215","journal-title":"Front Cardiovasc Med"},{"key":"5065_CR92","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.3390\/nu14071386","volume":"14","author":"C Chrysohoou","year":"2022","unstructured":"Chrysohoou C, Mantzouranis E, Dimitroglou Y, Mavroudis A, Tsioufis K (2022) Fluid and salt balance and the role of nutrition in heart failure. Nutrients 14:1386","journal-title":"Nutrients"},{"key":"5065_CR93","doi-asserted-by":"crossref","first-page":"102411","DOI":"10.1016\/j.cpcardiol.2024.102411","volume":"49","author":"Maryam","year":"2024","unstructured":"Maryam, Varghese TP, Tazneem B (2024) Unraveling the complex pathophysiology of heart failure: insights into the role of renin-angiotensin-aldosterone system (RAAS) and sympathetic nervous system (SNS). Curr Probl Cardiol 49:102411","journal-title":"Curr Probl Cardiol"},{"key":"5065_CR94","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.jacc.2009.05.015","volume":"54","author":"F Triposkiadis","year":"2009","unstructured":"Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J (2009) The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 54:1747\u20131762","journal-title":"J Am Coll Cardiol"},{"key":"5065_CR95","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/nrneph.2012.282","volume":"9","author":"M Nagase","year":"2013","unstructured":"Nagase M, Fujita T (2013) Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease. Nat Rev Nephrol 9:86\u201398","journal-title":"Nat Rev Nephrol"},{"issue":"67","key":"5065_CR96","first-page":"99","volume":"2016","author":"N Ayuzawa","year":"1979","unstructured":"Ayuzawa N, Nagase M, Ueda K, Nishimoto M, Kawarazaki W, Marumo T et al (1979) Rac1-mediated activation of mineralocorticoid receptor in pressure overload-induced cardiac injury. Hypertens Dallas Tex 2016(67):99\u2013106","journal-title":"Hypertens Dallas Tex"},{"key":"5065_CR97","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3390\/md20010061","volume":"20","author":"S Geahchan","year":"2022","unstructured":"Geahchan S, Baharlouei P, Rahman A (2022) Marine collagen: a promising biomaterial for wound healing, skin anti-aging, and bone regeneration. Mar Drugs 20:61","journal-title":"Mar Drugs"},{"key":"5065_CR98","doi-asserted-by":"crossref","first-page":"3947","DOI":"10.3892\/mmr.2017.7061","volume":"16","author":"C Zhu","year":"2017","unstructured":"Zhu C, Zhang W, Liu J, Mu B, Zhang F, Lai N et al (2017) Marine collagen peptides reduce endothelial cell injury in diabetic rats by inhibiting apoptosis and the expression of coupling factor 6 and microparticles. Mol Med Rep 16:3947\u20133957","journal-title":"Mol Med Rep"},{"key":"5065_CR99","doi-asserted-by":"crossref","first-page":"10501","DOI":"10.1038\/s41598-017-11251-8","volume":"7","author":"K Yang","year":"2017","unstructured":"Yang K, Long Q, Saja K, Huang F, Pogwizd SM, Zhou L et al (2017) Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy. Sci Rep 7:10501","journal-title":"Sci Rep"},{"key":"5065_CR100","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12944-017-0430-9","volume":"16","author":"S Maierean","year":"2017","unstructured":"Maierean S, Serban M-C, Rizzo M, Lippi G, Sahebkar A, Banach M (2017) The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review. Lipids Health Dis 16:35","journal-title":"Lipids Health Dis"},{"key":"5065_CR101","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1194\/jlr.P036335","volume":"54","author":"A Genoux","year":"2013","unstructured":"Genoux A, Ruidavets J-B, Ferri\u00e8res J, Combes G, Lichtenstein L, Pons V et al (2013) Serum IF1 concentration is independently associated to HDL levels and to coronary heart disease: the GENES study. J Lipid Res 54:2550\u20132558","journal-title":"J Lipid Res"},{"key":"5065_CR102","doi-asserted-by":"crossref","first-page":"731","DOI":"10.7150\/ijbs.64956","volume":"18","author":"J-W Wu","year":"2022","unstructured":"Wu J-W, Hu H, Hua J-S, Ma L-K (2022) ATPase inhibitory factor 1 protects the heart from acute myocardial ischemia\/reperfusion injury through activating AMPK signaling pathway. Int J Biol Sci 18:731\u2013741","journal-title":"Int J Biol Sci"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-024-05065-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-024-05065-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-024-05065-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T14:14:08Z","timestamp":1739888048000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-024-05065-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,10]]},"references-count":102,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["5065"],"URL":"https:\/\/doi.org\/10.1007\/s11010-024-05065-2","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,10]]},"assertion":[{"value":"28 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}