{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T22:45:43Z","timestamp":1771368343076,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s11010-024-05203-w","type":"journal-article","created":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T19:03:06Z","timestamp":1736708586000},"page":"3695-3708","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The impact of combination of zofenopril and different diuretics on regression of myocardial reperfusion injury and oxidative status in spontaneously hypertensive rats"],"prefix":"10.1007","volume":"480","author":[{"given":"Maja","family":"Savic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevena","family":"Dragasevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmina","family":"Sretenovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarina","family":"Mihajlovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marijana","family":"Andjic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarina","family":"Djordjevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bozidar","family":"Pindovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Zivkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Srejovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Bolevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefani","family":"Bolevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Jakovljevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Nikolic Turnic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,12]]},"reference":[{"key":"5203_CR1","doi-asserted-by":"publisher","first-page":"1933","DOI":"10.1016\/S0140-6736(14)60107-0","volume":"383","author":"G Heusch","year":"2014","unstructured":"Heusch G, Libby P, Gersh B, Yellon D, B\u00f6hm M, Lopaschuk G, Opie L (2014) Cardiovascular remodelling in coronary artery disease and heart failure. Lancet 383:1933\u20131943. https:\/\/doi.org\/10.1016\/S0140-6736(14)60107-0","journal-title":"Lancet"},{"key":"5203_CR2","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1111\/bph.12811","volume":"172","author":"I Andreadou","year":"2015","unstructured":"Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P (2015) The role of gasotransmitters NO, H2S and CO in myocardial ischaemia\/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol 172:1587\u20131606. https:\/\/doi.org\/10.1111\/bph.12811","journal-title":"Br J Pharmacol"},{"issue":"22","key":"5203_CR3","doi-asserted-by":"publisher","first-page":"9669","DOI":"10.3390\/ijms22189669","volume":"7","author":"J Ku\u0107mierz","year":"2021","unstructured":"Ku\u0107mierz J, Fr\u0105k W, M\u0142ynarska E, Franczyk B, Rysz J (2021) Molecular interactions of arterial hypertension in its target organs. Int J Mol Sci 7(22):9669. https:\/\/doi.org\/10.3390\/ijms22189669","journal-title":"Int J Mol Sci"},{"key":"5203_CR4","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1177\/1074248413497257","volume":"19","author":"GC Roush","year":"2014","unstructured":"Roush GC, Kaur R, Ernst ME (2014) Diuretics: a review and update. J Cardiovasc Pharmacol Ther 19:5\u201313. https:\/\/doi.org\/10.1177\/1074248413497257","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"5203_CR5","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.21669.1","author":"M Doumas","year":"2020","unstructured":"Doumas M, Imprialos KP, Kallistratos MS, Manolis AJ (2020) Recent advances in understanding and managing resistant\/refractory hypertension. F1000Res. https:\/\/doi.org\/10.12688\/f1000research.21669.1","journal-title":"F1000Res"},{"key":"5203_CR6","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s11010-011-0766-9","volume":"352","author":"V Carnicelli","year":"2011","unstructured":"Carnicelli V, Frascarelli S, Zucchi R (2011) Effect of acute and chronic zofenopril administration on cardiac gene expression. Mol Cell Biochem 352:301\u2013307. https:\/\/doi.org\/10.1007\/s11010-011-0766-9","journal-title":"Mol Cell Biochem"},{"key":"5203_CR7","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1161\/01.HYP.0000122874.21730.81","volume":"43","author":"JM Chillon","year":"2004","unstructured":"Chillon JM, Baumbach GL (2004) Effects of indapamide, a thiazide-like diuretic, on structure of cerebral arterioles in hypertensive rats. Hypertension 43:1092\u20131097. https:\/\/doi.org\/10.1161\/01.HYP.0000122874.21730.81","journal-title":"Hypertension"},{"key":"5203_CR8","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1097\/FJC.0b013e318260e688","volume":"60","author":"P Milliez","year":"2012","unstructured":"Milliez P, Gomes S, Champ-Rigot L, Callebert J, Samuel JL, Delcayre C (2012) Effects of spironolactone alone and in addition to a \u03b2-blocker on myocardial histological and electrical remodeling in chronic severe failing rat hearts. J Cardiovasc Pharmacol 60:315\u2013321. https:\/\/doi.org\/10.1097\/FJC.0b013e318260e688","journal-title":"J Cardiovasc Pharmacol"},{"key":"5203_CR9","doi-asserted-by":"publisher","first-page":"9100","DOI":"10.3390\/ijms21239100","volume":"21","author":"JN Jeremic","year":"2020","unstructured":"Jeremic JN, Jakovljevic VL, Zivkovic VI, Srejovic IM, Bradic JV, Milosavljevic IM, Mitrovic SL, Jovicic NU, Bolevich SB, Svistunov AA, Tyagi SC, Jeremic NS (2020) Garlic derived diallyl trisulfide in experimental metabolic syndrome: metabolic effects and cardioprotective role. Int J Mol Sci 21:9100. https:\/\/doi.org\/10.3390\/ijms21239100","journal-title":"Int J Mol Sci"},{"key":"5203_CR10","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1258\/la.2007.06001e","volume":"43","author":"J Stypmann","year":"2009","unstructured":"Stypmann J, Engelen MA, Troatz C, Rothenburger M, Eckardt L, Tiemann K (2009) Echocardiographic assessment of global left ventricular function in mice. Lab Anim 43:127\u2013137. https:\/\/doi.org\/10.1258\/la.2007.06001e","journal-title":"Lab Anim"},{"key":"5203_CR11","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351\u2013358. https:\/\/doi.org\/10.1016\/0003-2697(79)90738-3","journal-title":"Anal Biochem"},{"key":"5203_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-x","volume":"126","author":"LC Green","year":"1982","unstructured":"Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR (1982) Analysis of nitrate, nitrite and [15N]nitrate in biological fluids. Anal Biochem 126:131\u2013138. https:\/\/doi.org\/10.1016\/0003-2697(82)90118-x","journal-title":"Anal Biochem"},{"key":"5203_CR13","first-page":"123","volume-title":"Handbook of methods for oxygen radical research","author":"C Auclair","year":"1985","unstructured":"Auclair C, Voisin E (1985) Nitroblue tetrazolium reduction. In: Greenvvald RA (ed) Handbook of methods for oxygen radical research. CRCPress, Boka Raton, pp 123\u2013132"},{"key":"5203_CR14","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0022-1759(80)90340-3","volume":"38","author":"E Pick","year":"1980","unstructured":"Pick E, Keisari Y (1980) A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture. J Immunol Methods 38:161\u2013170. https:\/\/doi.org\/10.1016\/0022-1759(80)90340-3","journal-title":"J Immunol Methods"},{"key":"5203_CR15","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/s0076-6879(84)05016-3","volume":"105","author":"H Aebi","year":"1984","unstructured":"Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121\u2013126. https:\/\/doi.org\/10.1016\/s0076-6879(84)05016-3","journal-title":"Methods Enzymol"},{"key":"5203_CR16","doi-asserted-by":"publisher","first-page":"3170","DOI":"10.1016\/S0021-9258(19)45228-9","volume":"25","author":"HP Misra","year":"1972","unstructured":"Misra HP, Fridovich I (1972) The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 25:3170\u20133175","journal-title":"J Biol Chem"},{"key":"5203_CR17","first-page":"112","volume-title":"Red cell metabolism, a manual of biochemical methods","author":"E Beutler","year":"1975","unstructured":"Beutler E (1975) Reduced glutathione (GSH). In: Beutler E (ed) Red cell metabolism, a manual of biochemical methods. Grune and Straton, New York, pp 112\u2013114"},{"key":"5203_CR18","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1517\/14656566.2014.879118","volume":"15","author":"J Tamargo","year":"2014","unstructured":"Tamargo J, Segura J, Ruilope LM (2014) Diuretics in the treatment of hypertension. Part 1: thiazide and thiazide-like diuretics. Expert Opin Pharmacother 15:527\u2013547. https:\/\/doi.org\/10.1517\/14656566.2014.879118","journal-title":"Expert Opin Pharmacother"},{"key":"5203_CR19","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1097\/01.hjh.0000187253.35245.dc","volume":"23","author":"B Dahl\u00f6f","year":"2005","unstructured":"Dahl\u00f6f B, Gosse P, Gu\u00e9ret P, Dubourg O, de Simone G, Schmieder R, Karpov Y, Garc\u00eda-Puig J, Matos L, De Leeuw PW, Degaute JP, Magometschnigg D (2005) Perindopril\/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. J Hypertens 23:2063\u20132070. https:\/\/doi.org\/10.1097\/01.hjh.0000187253.35245.dc","journal-title":"J Hypertens"},{"key":"5203_CR20","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1038\/hr.2009.103","volume":"32","author":"K Node","year":"2009","unstructured":"Node K (2009) Benefits and risks of combination therapy in hypertension. Hypertens Res 32:727\u2013728. https:\/\/doi.org\/10.1038\/hr.2009.103","journal-title":"Hypertens Res"},{"key":"5203_CR21","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1056\/NEJMra000050","volume":"345","author":"KT Weber","year":"2001","unstructured":"Weber KT (2001) Aldosterone in congestive heart failure. N Engl J Med 345:1689\u20131697. https:\/\/doi.org\/10.1056\/NEJMra000050","journal-title":"N Engl J Med"},{"key":"5203_CR22","doi-asserted-by":"publisher","DOI":"10.1177\/2048004014522440","author":"M Hargovan","year":"2014","unstructured":"Hargovan M, Ferro A (2014) Aldosterone synthase inhibitors in hypertension: current status and future possibilities. JRSM Cardiovasc Dis. https:\/\/doi.org\/10.1177\/2048004014522440","journal-title":"JRSM Cardiovasc Dis"},{"key":"5203_CR23","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1161\/CIRCRESAHA.115.306565","volume":"118","author":"JG Travers","year":"2016","unstructured":"Travers JG, Kamal FA, Robbins J, Yutzey KE, Blaxall BC (2016) Cardiac fibrosis: the fibroblast awakens. Circ Res 118:1021\u20131040. https:\/\/doi.org\/10.1161\/CIRCRESAHA.115.306565","journal-title":"Circ Res"},{"key":"5203_CR24","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1093\/ajh\/hpy120","volume":"31","author":"M Buonafine","year":"2018","unstructured":"Buonafine M, Bonnard B, Jaisser F (2018) Mineralocorticoid receptor and cardiovascular disease. Am J Hypertens 31:1165\u20131174. https:\/\/doi.org\/10.1093\/ajh\/hpy120","journal-title":"Am J Hypertens"},{"key":"5203_CR25","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1007\/s11010-022-04622-x","volume":"478","author":"N Dragasevic","year":"2023","unstructured":"Dragasevic N, Savic M, Mihajlovic K, Zivkovic V, Andjic M, Draginic N, Zdravkovic N, Bolevich S, Bolevich S, Jakovljevic V, Nikolic Turnic T (2023) The impact of different diuretics on regression of myocardial reperfusion injury in spontaneously hypertensive rats. Mol Cell Biochem 478:1803\u20131812. https:\/\/doi.org\/10.1007\/s11010-022-04622-x","journal-title":"Mol Cell Biochem"},{"key":"5203_CR26","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000069722","volume":"99","author":"E Yahiro","year":"2003","unstructured":"Yahiro E, Ideishi M, Wang LX, Urata H, Kumagai K, Arakawa K, Saku K (2003) Reperfusion-induced arrhythmias are suppressed by inhibition of the angiotensin II type 1 receptor. Cardiology 99:61\u201367. https:\/\/doi.org\/10.1159\/000069722","journal-title":"Cardiology"},{"key":"5203_CR27","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1177\/1074248414553231","volume":"20","author":"EI Dedkov","year":"2015","unstructured":"Dedkov EI, Bogatyryov Y, McCooey DS, Christensen LP, Weiss RM, Tomanek RJ (2015) Effect of chronic heart rate reduction by I(f) current inhibitor ivabradine on left ventricular remodeling and systolic performance in middle-aged rats with postmyocardial infarction heart failure. J Cardiovasc Pharmacol Ther 20:299\u2013312. https:\/\/doi.org\/10.1177\/1074248414553231","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"5203_CR28","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1093\/cvr\/cvy286","volume":"115","author":"DJ Hausenloy","year":"2019","unstructured":"Hausenloy DJ, Chilian W, Crea F, Davidson SM, Ferdinandy P, Garcia-Dorado D, van Royen N, Schulz R, Heusch G (2019) The coronary circulation in acute myocardial ischaemia\/reperfusion injury: a target for cardioprotection. Cardiovasc Res 115:1143\u20131155. https:\/\/doi.org\/10.1093\/cvr\/cvy286","journal-title":"Cardiovasc Res"},{"key":"5203_CR29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1093\/cvr\/cvr271","volume":"94","author":"G Heusch","year":"2012","unstructured":"Heusch G, Kleinbongard P, Skyschally A, Levkau B, Schulz R, Erbel R (2012) The coronary circulation in cardioprotection: more than just one confounder. Cardiovasc Res 94:237\u2013245. https:\/\/doi.org\/10.1093\/cvr\/cvr271","journal-title":"Cardiovasc Res"},{"key":"5203_CR30","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1097\/HJH.0000000000000826","volume":"34","author":"S M\u00f8lgaard","year":"2016","unstructured":"M\u00f8lgaard S, Faricelli B, Salomonsson M, Engstr\u00f8m T, Treiman M (2016) Increased myocardial vulnerability to ischemia-reperfusion injury in the presence of left ventricular hypertrophy. J Hypertens 34:513\u2013523. https:\/\/doi.org\/10.1097\/HJH.0000000000000826","journal-title":"J Hypertens"},{"key":"5203_CR31","doi-asserted-by":"publisher","first-page":"131","DOI":"10.2459\/JCM.0000000000000435","volume":"18","author":"P Pagliaro","year":"2017","unstructured":"Pagliaro P, Penna C (2017) Hypertension, hypertrophy, and reperfusion injury. J Cardiovasc Med (Hagerstown) 18:131\u2013135. https:\/\/doi.org\/10.2459\/JCM.0000000000000435","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"5203_CR32","doi-asserted-by":"publisher","first-page":"H1417","DOI":"10.1152\/ajpheart.00089.2013","volume":"305","author":"SI Dikalov","year":"2013","unstructured":"Dikalov SI, Ungvari Z (2013) Role of mitochondrial oxidative stress in hypertension. Am J Physiol Heart Circ Physiol 305:H1417-1427. https:\/\/doi.org\/10.1152\/ajpheart.00089.2013","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"5203_CR33","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1161\/01.HYP.0000138070.47616.9d","volume":"44","author":"RM Touyz","year":"2004","unstructured":"Touyz RM (2004) Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension 44:248\u2013252. https:\/\/doi.org\/10.1161\/01.HYP.0000138070.47616.9d","journal-title":"Hypertension"},{"key":"5203_CR34","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1097\/PSY.0000000000000324","volume":"78","author":"C Zuccarella-Hackl","year":"2016","unstructured":"Zuccarella-Hackl C, von K\u00e4nel R, Thomas L, Hauser M, Kuebler U, Widmer HR, Wirtz PH (2016) Macrophage superoxide anion production in essential hypertension: associations with biological and psychological cardiovascular risk factors. Psychosom Med 78:750\u2013757. https:\/\/doi.org\/10.1097\/PSY.0000000000000324","journal-title":"Psychosom Med"},{"key":"5203_CR35","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1055\/s-0035-1548765","volume":"123","author":"R Brito","year":"2015","unstructured":"Brito R, Castillo G, Gonz\u00e1lez J, Valls N, Rodrigo R (2015) Oxidative stress in hypertension: mechanisms and therapeutic opportunities. Exp Clin Endocrinol Diabetes 123:325\u2013335. https:\/\/doi.org\/10.1055\/s-0035-1548765","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"5203_CR36","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1111\/j.1476-5381.2010.00678.x","volume":"160","author":"CS Ceron","year":"2010","unstructured":"Ceron CS, Castro MM, Rizzi E, Montenegro MF, Fontana V, Salgado MC, Gerlach RF, Tanus-Santos JE (2010) Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension. Br J Pharmacol 160:77\u201387. https:\/\/doi.org\/10.1111\/j.1476-5381.2010.00678.x","journal-title":"Br J Pharmacol"},{"key":"5203_CR37","doi-asserted-by":"publisher","first-page":"e003531","DOI":"10.1161\/JAHA.116.003531","volume":"5","author":"E Donnarumma","year":"2016","unstructured":"Donnarumma E, Ali MJ, Rushing AM, Scarborough AL, Bradley JM, Organ CL, Islam KN, Polhemus DJ, Evangelista S, Cirino G, Jenkins JS, Patel RA, Lefer DJ, Goodchild TT (2016) Zofenopril protects against myocardial ischemia-reperfusion injury by increasing nitric oxide and hydrogen sulfide bioavailability. J Am Heart Assoc 5:e003531. https:\/\/doi.org\/10.1161\/JAHA.116.003531","journal-title":"J Am Heart Assoc"},{"key":"5203_CR38","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1124\/mol.113.085878","volume":"84","author":"F Ma","year":"2013","unstructured":"Ma F, Lin F, Chen C, Cheng J, Zeldin DC, Wang Y, Wang DW (2013) Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney. Mol Pharmacol 84:286\u2013295. https:\/\/doi.org\/10.1124\/mol.113.085878","journal-title":"Mol Pharmacol"},{"key":"5203_CR39","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1161\/01.CIR.0000153800.09920.40","volume":"111","author":"GM Kuster","year":"2005","unstructured":"Kuster GM, Kotlyar E, Rude MK, Siwik DA, Liao R, Colucci WS, Sam F (2005) Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload. Circulation 111:420\u2013427. https:\/\/doi.org\/10.1161\/01.CIR.0000153800.09920.40","journal-title":"Circulation"},{"key":"5203_CR40","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1161\/01.CIR.0000091405.00772.6E","volume":"108","author":"B Pitt","year":"2003","unstructured":"Pitt B, Reichek N, Willenbrock R, Zannad F, Phillips RA, Roniker B, Kleiman J, Krause S, Burns D, Williams GH (2003) Effects of eplerenone, enalapril, and eplerenone\/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. Circulation 108:1831\u20131838. https:\/\/doi.org\/10.1161\/01.CIR.0000091405.00772.6E","journal-title":"Circulation"},{"key":"5203_CR41","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1001\/jama.2013.905","volume":"309","author":"F Edelmann","year":"2013","unstructured":"Edelmann F, Wachter R, Schmidt AG, Kraigher-Krainer E, Colantonio C, Kamke W, Duvinage A, Stahrenberg R, Durstewitz K, L\u00f6ffler M, D\u00fcngen HD, Tsch\u00f6pe C, Herrmann-Lingen C, Halle M, Hasenfuss G, Gelbrich G, Pieske B (2013) Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial. JAMA 309:781\u2013791. https:\/\/doi.org\/10.1001\/jama.2013.905","journal-title":"JAMA"},{"key":"5203_CR42","doi-asserted-by":"publisher","first-page":"e000790","DOI":"10.1161\/JAHA.114.000790","volume":"25","author":"OR Coelho-Filho","year":"2014","unstructured":"Coelho-Filho OR, Shah RV, Neilan TG, Mitchell R, Moreno H Jr, Kwong R, Jerosch-Herold M (2014) Cardiac magnetic resonance assessment of interstitial myocardial fibrosis and cardiomyocyte hypertrophy in hypertensive mice treated with spironolactone. J Am Heart Assoc 25:e000790. https:\/\/doi.org\/10.1161\/JAHA.114.000790","journal-title":"J Am Heart Assoc"},{"key":"5203_CR43","doi-asserted-by":"publisher","first-page":"F519","DOI":"10.1152\/ajprenal.00606.2018","volume":"317","author":"LE Morales-Buenrostro","year":"2019","unstructured":"Morales-Buenrostro LE, Ortega-Trejo JA, P\u00e9rez-Villalva R, Marino LA, Gonz\u00e1lez-Bobadilla Y, Ju\u00e1rez H, Zamora-Mej\u00eda FM, Gonz\u00e1lez N, Espinoza R, Barrera-Chimal J, Bobadilla NA (2019) Spironolactone reduces oxidative stress in living donor kidney transplantation: a randomized controlled trial. Am J Physiol Renal Physiol 317:F519\u2013F528. https:\/\/doi.org\/10.1152\/ajprenal.00606.2018","journal-title":"Am J Physiol Renal Physiol"},{"key":"5203_CR44","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.2215\/CJN.05300516","volume":"12","author":"M Medeiros","year":"2017","unstructured":"Medeiros M, Vel\u00e1squez-Jones L, Hern\u00e1ndez AM, Ram\u00f3n-Garc\u00eda G, Valverde S, Fuentes Y, Vargas A, Pati\u00f1o M, P\u00e9rez-Villalva R, Ortega-Trejo JA, Barrera-Chimal J, Bobadilla NA (2017) Randomized controlled trial of mineralocorticoid receptor blockade in children with chronic kidney allograft nephropathy. Clin J Am Soc Nephrol 12:1291\u20131300. https:\/\/doi.org\/10.2215\/CJN.05300516","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-024-05203-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-024-05203-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-024-05203-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T13:02:56Z","timestamp":1747918976000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-024-05203-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,12]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["5203"],"URL":"https:\/\/doi.org\/10.1007\/s11010-024-05203-w","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,12]]},"assertion":[{"value":"25 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The University of Kragujevac in Serbia\u2019s Faculty of Medical Sciences conducted this inquiry (approval number 01-10667\/1). The study procedure was carried out in compliance with the European Council Directive (86\/609\/EEC) and the ethical guidelines established by the faculty\u2019s ethical committee for laboratory animal welfare.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and\/or the editor(s). MDPI and\/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}