{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:19:07Z","timestamp":1791623947599,"version":"4.3.4"},"reference-count":267,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32241005"],"award-info":[{"award-number":["32241005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s11010-025-05376-y","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:17:22Z","timestamp":1756293442000},"page":"5995-6014","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Chronic stress, gut microbiota, and immunity: interconnections and implications for health"],"prefix":"10.1007","volume":"480","author":[{"given":"Hexiao","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Can","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wancheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoxin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"key":"5376_CR1","first-page":"179","volume":"374","author":"MD Smith","year":"2025","unstructured":"Smith MD, Wesselbaum D. Global evidence on the prevalence of and risk factors associated with stress. Journal of Affective Disorders. 2025 Apr 1;374:179\u201383.","journal-title":"Int Rev Neurobiol"},{"issue":"9914","key":"5376_CR2","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/S0140-6736(14)60093-3","volume":"383","author":"M Jackson","year":"2014","unstructured":"Jackson M (2014) The stress of life: a modern complaint? Lancet 383(9914):300\u2013301","journal-title":"Lancet"},{"issue":"5","key":"5376_CR3","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1016\/j.cell.2020.02.021","volume":"180","author":"CR Consiglio","year":"2020","unstructured":"Consiglio CR, Brodin P (2020) Stressful beginnings with long-term consequences. Cell 180(5):820\u2013821","journal-title":"Cell"},{"issue":"7","key":"5376_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e18338","volume":"9","author":"W Zhang","year":"2023","unstructured":"Zhang W, Zhang X, Yan D, Wang G, Wang Q, Ren X et al (2023) Establishment of insomnia model of chronic unpredictable stress in rats. Heliyon 9(7):e18338","journal-title":"Heliyon"},{"key":"5376_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2019.104501","volume":"111","author":"A Labanski","year":"2020","unstructured":"Labanski A, Langhorst J, Engler H, Elsenbruch S (2020) Stress and the brain-gut axis in functional and chronic-inflammatory gastrointestinal diseases: a transdisciplinary challenge. Psychoneuroendocrinology 111:104501","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"5376_CR6","doi-asserted-by":"publisher","first-page":"2221","DOI":"10.1038\/s41467-020-15920-7","volume":"11","author":"WZ Liu","year":"2020","unstructured":"Liu WZ, Zhang WH, Zheng ZH, Zou JX, Liu XX, Huang SH et al (2020) Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety. Nat Commun 11(1):2221","journal-title":"Nat Commun"},{"issue":"10","key":"5376_CR7","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s11886-019-1208-7","volume":"21","author":"E Iob","year":"2019","unstructured":"Iob E, Steptoe A (2019) Cardiovascular disease and hair cortisol: a novel biomarker of chronic stress. Curr Cardiol Rep 21(10):116","journal-title":"Curr Cardiol Rep"},{"issue":"23","key":"5376_CR8","doi-asserted-by":"publisher","first-page":"2726","DOI":"10.3390\/cells12232726","volume":"12","author":"E Knezevic","year":"2023","unstructured":"Knezevic E, Nenic K, Milanovic V, Knezevic NN (2023) The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells 12(23):2726","journal-title":"Cells"},{"issue":"10","key":"5376_CR9","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.3389\/fonc.2020.01492","volume":"19","author":"S Dai","year":"2020","unstructured":"Dai S, Mo Y, Wang Y, Xiang B, Liao Q, Zhou M et al (2020) Chronic stress promotes cancer development. Front Oncol 19(10):1492","journal-title":"Front Oncol"},{"issue":"3","key":"5376_CR10","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1177\/0141076819890547","volume":"113","author":"W Bird","year":"2020","unstructured":"Bird W, Adamo G, Pitini E, Gray M, Jani A (2020) Reducing chronic stress to promote health in adults: the role of social prescriptions and social movements. J R Soc Med 113(3):105\u2013109","journal-title":"J R Soc Med"},{"key":"5376_CR11","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1111\/j.1749-6632.1999.tb08111.x","volume":"896","author":"A Baum","year":"1999","unstructured":"Baum A, Garofalo JP, Yali AM (1999) Socioeconomic status and chronic stress: does stress account for SES effects on health? Ann NY Acad Sci. 896:131\u201344","journal-title":"Ann NY Acad Sci."},{"key":"5376_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.738252","volume":"11","author":"H Hong","year":"2021","unstructured":"Hong H, Ji M, Lai D (2021) Chronic stress effects on tumor: pathway and mechanism. Front Oncol 11:738252","journal-title":"Front Oncol"},{"key":"5376_CR13","doi-asserted-by":"publisher","first-page":"1130989","DOI":"10.3389\/fpsyt.2023.1130989","volume":"14","author":"S Hassamal","year":"2023","unstructured":"Hassamal S (2023) Chronic stress, neuroinflammation, and depression: an overview of pathophysiological mechanisms and emerging anti-inflammatories. Front Psychiatry 14:1130989","journal-title":"Front Psychiatry"},{"issue":"14","key":"5376_CR14","doi-asserted-by":"publisher","first-page":"8773","DOI":"10.3390\/ijerph19148773","volume":"19","author":"FS Hussenoeder","year":"2022","unstructured":"Hussenoeder FS, Conrad I, Pabst A, Luppa M, Stein J, Engel C et al (2022) Different areas of chronic stress and their associations with depression. IJERPH 19(14):8773","journal-title":"IJERPH"},{"key":"5376_CR15","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-024-01024-y","author":"V Vaccarino","year":"2024","unstructured":"Vaccarino V, Bremner JD (2024) Stress and cardiovascular disease: an update. Nat Rev Cardiol. https:\/\/doi.org\/10.1038\/s41569-024-01024-y","journal-title":"Nat Rev Cardiol"},{"key":"5376_CR16","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3389\/fnbeh.2018.00127","volume":"12","author":"LD Godoy","year":"2018","unstructured":"Godoy LD, Rossignoli MT, Delfino-Pereira P, Garcia-Cairasco N, de Lima Umeoka EH (2018) A comprehensive overview on stress neurobiology: basic concepts and clinical implications. Front Behav Neurosci 12:127","journal-title":"Front Behav Neurosci"},{"issue":"23","key":"5376_CR17","doi-asserted-by":"publisher","first-page":"2726","DOI":"10.3390\/cells12232726","volume":"12","author":"E Knezevic","year":"2023","unstructured":"Knezevic E, Nenic K, Milanovic V, Knezevic NN (2023) The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells 12(23):2726","journal-title":"Cells"},{"issue":"4","key":"5376_CR18","doi-asserted-by":"publisher","first-page":"209","DOI":"10.5483\/BMBRep.2015.48.4.275","volume":"48","author":"DY Lee","year":"2015","unstructured":"Lee DY, Kim E, Choi MH (2015) Technical and clinical aspects of cortisol as a biochemical marker of chronic stress. BMB Rep 48(4):209\u2013216","journal-title":"BMB Rep"},{"issue":"105","key":"5376_CR19","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.psyneuen.2019.02.021","volume":"1","author":"N Rohleder","year":"2019","unstructured":"Rohleder N (2019) Stress and inflammation\u2014the need to address the gap in the transition between acute and chronic stress effects. Psychoneuroendocrinology 1(105):164\u2013171","journal-title":"Psychoneuroendocrinology"},{"issue":"6","key":"5376_CR20","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1210\/endrev\/bnad021","volume":"44","author":"L Langouche","year":"2023","unstructured":"Langouche L, T\u00e9blick A, Gunst J, Van den Berghe G (2023) The hypothalamus-pituitary-adrenocortical response to critical illness: a concept in need of revision. Endocr Rev 44(6):1096\u20131106","journal-title":"Endocr Rev"},{"issue":"5","key":"5376_CR21","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1158\/0008-5472.CAN-22-3705","volume":"84","author":"Q Cao","year":"2024","unstructured":"Cao Q, Zhao M, Su Y, Liu S, Lin Y, Da H et al (2024) Chronic stress dampens lactobacillus johnsonii-mediated tumor suppression to enhance colorectal cancer progression. Cancer Res 84(5):771\u2013784","journal-title":"Cancer Res"},{"issue":"9","key":"5376_CR22","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1016\/j.biopsych.2021.11.023","volume":"91","author":"I Su\u00e1rez-Pereira","year":"2022","unstructured":"Su\u00e1rez-Pereira I, Llorca-Torralba M, Bravo L, Camarena-Delgado C, Soriano-Mas C, Berrocoso E (2022) The role of the locus coeruleus in pain and associated stress-related disorders. Biol Psychiatry 91(9):786\u2013797","journal-title":"Biol Psychiatry"},{"key":"5376_CR23","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1146\/annurev-med-042320-014032","volume":"73","author":"EA Mayer","year":"2022","unstructured":"Mayer EA, Nance K, Chen S (2022) The gut-brain axis. Annu Rev Med. 73:439\u201353","journal-title":"Annu Rev Med."},{"issue":"10","key":"5376_CR24","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1093\/procel\/pwad026","volume":"14","author":"Q Wang","year":"2023","unstructured":"Wang Q, Yang Q, Liu X (2023) The microbiota-gut-brain axis and neurodevelopmental disorders. Protein Cell 14(10):762\u2013775","journal-title":"Protein Cell"},{"issue":"9","key":"5376_CR25","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/s41569-024-01024-y","volume":"21","author":"V Vaccarino","year":"2024","unstructured":"Vaccarino V, Bremner JD (2024) Stress and cardiovascular disease: an update. Nat Rev Cardiol 21(9):603\u2013616","journal-title":"Nat Rev Cardiol"},{"key":"5376_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.07.019","author":"H Chang","year":"2024","unstructured":"Chang H, Perkins MH, Novaes LS, Qian F, Zhang T, Neckel PH et al (2024) Stress-sensitive neural circuits change the gut microbiome via duodenal glands. Cell. https:\/\/doi.org\/10.1016\/j.cell.2024.07.019","journal-title":"Cell"},{"issue":"10071","key":"5376_CR27","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/S0140-6736(16)31714-7","volume":"389","author":"A Tawakol","year":"2017","unstructured":"Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y et al (2017) Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. Lancet 389(10071):834\u2013845","journal-title":"Lancet"},{"issue":"8","key":"5376_CR28","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.120.010931","volume":"13","author":"MT Osborne","year":"2020","unstructured":"Osborne MT, Shin LM, Mehta NN, Pitman RK, Fayad ZA, Tawakol A (2020) Disentangling the links between psychosocial stress and cardiovascular disease. Circ Cardiovasc Imaging 13(8):e010931","journal-title":"Circ Cardiovasc Imaging"},{"issue":"19","key":"5376_CR29","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1093\/eurheartj\/ehae149","volume":"45","author":"C Gharios","year":"2024","unstructured":"Gharios C, van Leent MMT, Chang HL, Abohashem S, O\u2019Connor D, Osborne MT et al (2024) Cortico-limbic interactions and carotid atherosclerotic burden during chronic stress exposure. Eur Heart J 45(19):1753\u20131764","journal-title":"Eur Heart J"},{"issue":"9","key":"5376_CR30","doi-asserted-by":"publisher","first-page":"4999","DOI":"10.3390\/ijms23094999","volume":"23","author":"OV Dolotov","year":"2022","unstructured":"Dolotov OV, Inozemtseva LS, Myasoedov NF, Grivennikov IA (2022) Stress-induced depression and Alzheimer\u2019s disease: focus on astrocytes. Int J Mol Sci 23(9):4999","journal-title":"Int J Mol Sci"},{"issue":"10","key":"5376_CR31","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.3390\/ijms18102150","volume":"18","author":"NG Burford","year":"2017","unstructured":"Burford NG, Webster NA, Cruz-Topete D (2017) Hypothalamic-pituitary-adrenal axis modulation of glucocorticoids in the cardiovascular system. Int J Mol Sci 18(10):2150","journal-title":"Int J Mol Sci"},{"issue":"6","key":"5376_CR32","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1210\/endrev\/bnad016","volume":"44","author":"R Pofi","year":"2023","unstructured":"Pofi R, Caratti G, Ray DW, Tomlinson JW (2023) Treating the side effects of exogenous glucocorticoids; can we separate the good from the bad? Endocr Rev 44(6):975\u20131011","journal-title":"Endocr Rev"},{"issue":"6284","key":"5376_CR33","doi-asserted-by":"publisher","first-page":"aaf1098","DOI":"10.1126\/science.aaf1098","volume":"352","author":"MG Netea","year":"2016","unstructured":"Netea MG, Joosten LAB, Latz E, Mills KHG, Natoli G, Stunnenberg HG et al (2016) Trained immunity: a program of innate immune memory in health and disease. Science. 352(6284):aaf1098","journal-title":"Science."},{"issue":"1","key":"5376_CR34","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.immuni.2022.12.008","volume":"56","author":"J Park","year":"2023","unstructured":"Park J, Hsueh PC, Li Z, Ho PC (2023) Microenvironment-driven metabolic adaptations guiding CD8+ T cell anti-tumor immunity. Immunity 56(1):32\u201342","journal-title":"Immunity"},{"issue":"15","key":"5376_CR35","doi-asserted-by":"publisher","first-page":"e35509","DOI":"10.1016\/j.heliyon.2024.e35509","volume":"10","author":"F Ghaedrahmati","year":"2024","unstructured":"Ghaedrahmati F, Esmaeil N, Akbari V, Ashrafi F (2024) More balance toward activating receptors and cytotoxic activity of NK cells ex vivo differentiated from human umbilical cord blood-derived CD34+ stem cells in comparison with peripheral blood NK cells. Heliyon 10(15):e35509","journal-title":"Heliyon"},{"issue":"7","key":"5376_CR36","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/s41423-020-0477-9","volume":"17","author":"S Capellino","year":"2020","unstructured":"Capellino S, Claus M, Watzl C (2020) Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine. Cell Mol Immunol 17(7):705\u2013711","journal-title":"Cell Mol Immunol"},{"issue":"2","key":"5376_CR37","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/s41571-020-0426-7","volume":"18","author":"JA Myers","year":"2021","unstructured":"Myers JA, Miller JS (2021) Exploring the NK cell platform for cancer immunotherapy. Nat Rev Clin Oncol 18(2):85\u2013100","journal-title":"Nat Rev Clin Oncol"},{"issue":"1","key":"5376_CR38","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s12974-020-01787-4","volume":"17","author":"D Li","year":"2020","unstructured":"Li D, Wang Y, Jin X, Hu D, Xia C, Xu H et al (2020) NK cell-derived exosomes carry miR-207 and alleviate depression-like symptoms in mice. J Neuroinflammation 17(1):126","journal-title":"J Neuroinflammation"},{"issue":"22","key":"5376_CR39","doi-asserted-by":"publisher","first-page":"e2201135","DOI":"10.1002\/advs.202201135","volume":"9","author":"M Zhang","year":"2022","unstructured":"Zhang M, Shao W, Yang T, Liu H, Guo S, Zhao D et al (2022) Conscription of immune cells by light-activatable silencing NK-derived exosome (LASNEO) for Synergetic tumor eradication. Adv Sci (Weinh) 9(22):e2201135","journal-title":"Adv Sci (Weinh)"},{"key":"5376_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2020.102975","volume":"59","author":"G Xie","year":"2020","unstructured":"Xie G, Dong H, Liang Y, Ham JD, Rizwan R, Chen J (2020) CAR-NK cells: a promising cellular immunotherapy for cancer. EBioMedicine 59:102975","journal-title":"EBioMedicine"},{"issue":"1","key":"5376_CR41","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1186\/s13287-023-03345-0","volume":"14","author":"C Zhou","year":"2023","unstructured":"Zhou C, Zhang B, Yang Y, Jiang Q, Li T, Gong J et al (2023) Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing. Stem Cell Res Ther 14(1):107","journal-title":"Stem Cell Res Ther"},{"issue":"4","key":"5376_CR42","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1182\/blood.V99.4.1449","volume":"99","author":"D Zeng","year":"2002","unstructured":"Zeng D, Hoffmann P, Lan F, Huie P, Higgins J, Strober S (2002) Unique patterns of surface receptors, cytokine secretion, and immune functions distinguish T cells in the bone marrow from those in the periphery: impact on allogeneic bone marrow transplantation. Blood 99(4):1449\u20131457","journal-title":"Blood"},{"issue":"5","key":"5376_CR43","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.stem.2023.04.005","volume":"30","author":"X Hao","year":"2023","unstructured":"Hao X, Shen Y, Chen N, Zhang W, Valverde E, Wu L et al (2023) Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal. Cell Stem Cell 30(5):648-664.e8","journal-title":"Cell Stem Cell"},{"issue":"8390","key":"5376_CR44","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1016\/S0140-6736(84)91819-1","volume":"1","author":"PC Rogers","year":"1984","unstructured":"Rogers PC, Bleyer WA, Coccia P, Lukens JN, Siegel S, Sather H et al (1984) Yield of unpredicted bone-marrow relapse diagnosed by routine marrow aspiration in children with acute lymphoblastic leukaemia: a report from the Children\u2019s Cancer Study Group. Lancet. 1(8390):1320\u20132","journal-title":"Lancet."},{"issue":"5","key":"5376_CR45","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/j.stem.2023.04.001","volume":"30","author":"S Beneyto-Calabuig","year":"2023","unstructured":"Beneyto-Calabuig S, Merbach AK, Kniffka JA, Antes M, Szu-Tu C, Rohde C et al (2023) Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia. Cell Stem Cell 30(5):706-721.e8","journal-title":"Cell Stem Cell"},{"issue":"4","key":"5376_CR46","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/s41571-021-00593-y","volume":"19","author":"AK Dutta","year":"2022","unstructured":"Dutta AK, Alberge JB, Sklavenitis-Pistofidis R, Lightbody ED, Getz G, Ghobrial IM (2022) Single-cell profiling of tumour evolution in multiple myeloma\u2014opportunities for precision medicine. Nat Rev Clin Oncol. 19(4):223\u201336","journal-title":"Nat Rev Clin Oncol."},{"issue":"1","key":"5376_CR47","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1097\/HEP.0000000000000270","volume":"78","author":"A Guillot","year":"2023","unstructured":"Guillot A, Winkler M, Silva Afonso M, Aggarwal A, Lopez D, Berger H et al (2023) Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression. Hepatology 78(1):150\u2013166","journal-title":"Hepatology"},{"issue":"2","key":"5376_CR48","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.surg.2022.04.056","volume":"172","author":"LS Kelly","year":"2022","unstructured":"Kelly LS, Munley JA, Pons EE, Kannan KB, Apple CG, Thompson CW et al (2022) Mechanisms of improved erythroid progenitor growth with removal of chronic stress after trauma. Surgery 172(2):759\u2013765","journal-title":"Surgery"},{"issue":"9","key":"5376_CR49","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1089\/sur.2023.154","volume":"24","author":"GS Gillies","year":"2023","unstructured":"Gillies GS, Munley JA, Kelly LS, Pons EE, Kannan KB, Bible LE et al (2023) Anemia recovery after lung contusion, hemorrhagic shock, and chronic stress is gender-specific in a rat model. Surg Infect (Larchmt) 24(9):773\u2013781","journal-title":"Surg Infect (Larchmt)"},{"issue":"1","key":"5376_CR50","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/TA.0000000000000686","volume":"79","author":"LE Bible","year":"2015","unstructured":"Bible LE, Pasupuleti LV, Gore AV, Sifri ZC, Kannan KB, Mohr AM (2015) Chronic restraint stress after injury and shock is associated with persistent anemia despite prolonged elevation in erythropoietin levels. J Trauma Acute Care Surg 79(1):91\u201397","journal-title":"J Trauma Acute Care Surg"},{"issue":"2","key":"5376_CR51","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1097\/TA.0000000000003821","volume":"94","author":"LS Kelly","year":"2023","unstructured":"Kelly LS, Munley JA, Pons EE, Coldwell PS, Kannan KB, Efron PA et al (2023) Multicompartmental trauma alters bone marrow erythroblastic islands. J Trauma Acute Care Surg 94(2):197\u2013204","journal-title":"J Trauma Acute Care Surg"},{"issue":"1","key":"5376_CR52","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/ncpneph0655","volume":"4","author":"K van der Putten","year":"2008","unstructured":"van der Putten K, Braam B, Jie KE, Gaillard CAJM (2008) Mechanisms of disease: erythropoietin resistance in patients with both heart and kidney failure. Nat Clin Pract Nephrol 4(1):47\u201357","journal-title":"Nat Clin Pract Nephrol"},{"key":"5376_CR53","doi-asserted-by":"publisher","first-page":"116008","DOI":"10.1016\/j.bcp.2023.116008","volume":"220","author":"H Zou","year":"2024","unstructured":"Zou H, Wong RSM, Yan X (2024) Thrombopoietin treats erythropoietin resistance by correcting EPO-induced progenitorcell depletion. Biochem Pharmacol 220:116008","journal-title":"Biochem Pharmacol"},{"issue":"2","key":"5376_CR54","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.neuron.2020.06.002","volume":"107","author":"E Beurel","year":"2020","unstructured":"Beurel E, Toups M, Nemeroff CB (2020) The bidirectional relationship of depression and inflammation: double trouble. Neuron 107(2):234\u2013256","journal-title":"Neuron"},{"issue":"3","key":"5376_CR55","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1038\/s41573-021-00368-1","volume":"21","author":"WC Drevets","year":"2022","unstructured":"Drevets WC, Wittenberg GM, Bullmore ET, Manji HK (2022) Immune targets for therapeutic development in depression: towards precision medicine. Nat Rev Drug Discov. 21(3):224\u201344","journal-title":"Nat Rev Drug Discov."},{"issue":"6","key":"5376_CR56","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.3390\/nu15061518","volume":"15","author":"Y Zheng","year":"2023","unstructured":"Zheng Y, Zhang L, Bonfili L, de Vivo L, Eleuteri AM, Bellesi M (2023) Probiotics supplementation attenuates inflammation and oxidative stress induced by chronic sleep restriction. Nutrients 15(6):1518","journal-title":"Nutrients"},{"key":"5376_CR57","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.psyneuen.2019.02.021","volume":"105","author":"N Rohleder","year":"2019","unstructured":"Rohleder N (2019) Stress and inflammation\u2014the need to address the gap in the transition between acute and chronic stress effects. Psychoneuroendocrinology 105:164\u2013171","journal-title":"Psychoneuroendocrinology"},{"issue":"13","key":"5376_CR58","doi-asserted-by":"publisher","first-page":"896601","DOI":"10.3389\/fphar.2022.896601","volume":"15","author":"G Xu","year":"2022","unstructured":"Xu G, Zou T, Deng L, Yang G, Guo T, Wang Y et al (2022) Nonerythropoietic erythropoietin mimetic peptide ARA290 ameliorates chronic stress-induced depression-like behavior and inflammation in mice. Front Pharmacol 15(13):896601","journal-title":"Front Pharmacol"},{"issue":"4","key":"5376_CR59","doi-asserted-by":"publisher","first-page":"410","DOI":"10.14336\/AD.2016.1209","volume":"8","author":"R Wang","year":"2017","unstructured":"Wang R, Li J, Duan Y, Tao Z, Zhao H, Luo Y (2017) Effects of erythropoietin on gliogenesis during cerebral ischemic\/reperfusion recovery in adult mice. Aging Dis 8(4):410\u2013419","journal-title":"Aging Dis"},{"issue":"2","key":"5376_CR60","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/j.yexcr.2017.11.002","volume":"361","author":"S Wei","year":"2017","unstructured":"Wei S, Luo C, Yu S, Gao J, Liu C, Wei Z et al (2017) Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR\/JAK2-STAT3 pathway. Exp Cell Res. 361(2):342\u201352","journal-title":"Exp Cell Res."},{"key":"5376_CR61","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.brainresbull.2021.10.005","volume":"177","author":"JY Gu","year":"2021","unstructured":"Gu JY, Xu YW, Feng LP, Dong J, Zhao LQ, Liu C et al (2021) Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats. Brain Res Bull 177:252\u2013262","journal-title":"Brain Res Bull"},{"key":"5376_CR62","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2020.113553","volume":"337","author":"R Wang","year":"2021","unstructured":"Wang R, Zhang S, Yang Z, Zheng Y, Yan F, Tao Z et al (2021) Mutant erythropoietin enhances white matter repair via the JAK2\/STAT3 and C\/EBP\u03b2 pathway in middle-aged mice following cerebral ischemia and reperfusion. Exp Neurol 337:113553","journal-title":"Exp Neurol"},{"issue":"4","key":"5376_CR63","doi-asserted-by":"publisher","first-page":"BSR20181584","DOI":"10.1042\/BSR20181584","volume":"39","author":"M Tian","year":"2019","unstructured":"Tian M, Yang M, Li Z, Wang Y, Chen W, Yang L et al (2019) Fluoxetine suppresses inflammatory reaction in microglia under OGD\/R challenge via modulation of NF-\u03baB signaling. Biosci Rep. 39(4):BSR20181584","journal-title":"Biosci Rep."},{"issue":"3","key":"5376_CR64","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.ccell.2024.01.013","volume":"42","author":"XY He","year":"2024","unstructured":"He XY, Gao Y, Ng D, Michalopoulou E, George S, Adrover JM et al (2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell 42(3):474-486.e12","journal-title":"Cancer Cell"},{"issue":"13","key":"5376_CR65","doi-asserted-by":"publisher","first-page":"2823","DOI":"10.1016\/j.cell.2023.05.001","volume":"186","author":"KM Schneider","year":"2023","unstructured":"Schneider KM, Blank N, Alvarez Y, Thum K, Lundgren P, Litichevskiy L et al (2023) The enteric nervous system relays psychological stress to intestinal inflammation. Cell 186(13):2823-2838.e20","journal-title":"Cell"},{"issue":"1","key":"5376_CR66","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12974-023-02693-1","volume":"20","author":"J Ma","year":"2023","unstructured":"Ma J, Wang R, Chen Y, Wang Z, Dong Y (2023) 5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption. J Neuroinflammation 20(1):23","journal-title":"J Neuroinflammation"},{"key":"5376_CR67","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2023.101994","volume":"89","author":"M Nimgampalle","year":"2023","unstructured":"Nimgampalle M, Chakravarthy H, Sharma S, Shree S, Bhat AR, Pradeepkiran JA et al (2023) Neurotransmitter systems in the etiology of major neurological disorders: emerging insights and therapeutic implications. Ageing Res Rev 89:101994","journal-title":"Ageing Res Rev"},{"issue":"363","key":"5376_CR68","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.bbr.2019.01.045","volume":"2","author":"C Zhang","year":"2019","unstructured":"Zhang C, Kalueff AV, Song C (2019) Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behav Brain Res 2(363):109\u2013117","journal-title":"Behav Brain Res"},{"issue":"6","key":"5376_CR69","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1007\/s11064-023-03857-4","volume":"48","author":"T Cong","year":"2023","unstructured":"Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z et al (2023) Blocking two-pore domain potassium channel TREK-1 inhibits the activation of A1-like reactive astrocyte through the NF-\u03baB signaling pathway in a rat model of major depressive disorder. Neurochem Res 48(6):1737\u20131754","journal-title":"Neurochem Res"},{"issue":"40","key":"5376_CR70","doi-asserted-by":"publisher","first-page":"13896","DOI":"10.1523\/JNEUROSCI.1515-12.2012","volume":"32","author":"S Rossi","year":"2012","unstructured":"Rossi S, Sacchetti L, Napolitano F, De Chiara V, Motta C, Studer V et al (2012) Interleukin-1\u03b2 causes anxiety by interacting with the endocannabinoid system. J Neurosci 32(40):13896\u201313905","journal-title":"J Neurosci"},{"issue":"4","key":"5376_CR71","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.biopsych.2021.03.010","volume":"90","author":"J Lopez","year":"2021","unstructured":"Lopez J, Bagot RC (2021) Defining valid chronic stress models for depression with female rodents. Biol Psychiat 90(4):226\u2013235","journal-title":"Biol Psychiat"},{"issue":"1","key":"5376_CR72","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.ctcp.2013.10.001","volume":"20","author":"ER Kasala","year":"2014","unstructured":"Kasala ER, Bodduluru LN, Maneti Y, Thipparaboina R (2014) Effect of meditation on neurophysiological changes in stress mediated depression. Complement Ther Clin Pract 20(1):74\u201380","journal-title":"Complement Ther Clin Pract"},{"issue":"4","key":"5376_CR73","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.bbi.2004.11.004","volume":"19","author":"MF Dallman","year":"2005","unstructured":"Dallman MF, Pecoraro NC, la Fleur SE (2005) Chronic stress and comfort foods: self-medication and abdominal obesity. Brain Behav Immun. 19(4):275\u201380","journal-title":"Brain Behav Immun."},{"issue":"11\u201312","key":"5376_CR74","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.nut.2007.08.008","volume":"23","author":"SJ Torres","year":"2007","unstructured":"Torres SJ, Nowson CA (2007) Relationship between stress, eating behavior, and obesity. Nutrition 23(11\u201312):887\u2013894","journal-title":"Nutrition"},{"issue":"5","key":"5376_CR75","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/PSY.0000000000001256","volume":"86","author":"CE Lyons","year":"2024","unstructured":"Lyons CE, Graves SI, Razzoli M, Jeganathan K, Mansk RP, McGonigle S et al (2024) Chronic social and psychological stress impact select neuropathologies in the PS19 mouse model of tauopathy. Psychosom Med 86(5):366\u2013378","journal-title":"Psychosom Med"},{"key":"5376_CR76","first-page":"1784","volume":"17","author":"M Nakayama","year":"2011","unstructured":"Nakayama M, Aihara M, Chen YN, Araie M, Tomita-Yokotani K, Iwashina T (2011) Neuroprotective effects of flavonoids on hypoxia-, glutamate-, and oxidative stress-induced retinal ganglion cell death. Mol Vis 17:1784\u20131793","journal-title":"Mol Vis"},{"issue":"1","key":"5376_CR77","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/s13205-022-03438-2","volume":"13","author":"IM Ibrahim","year":"2023","unstructured":"Ibrahim IM, Alsieni M, Almalki SG, Alqurashi YE, Kumar V (2023) Comparative evaluation of natural neuroprotectives and their combinations on chronic immobilization stress-induced depression in experimental mice. 3 Biotech. 13(1):22","journal-title":"3 Biotech."},{"issue":"8","key":"5376_CR78","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1001\/archpsyc.60.8.789","volume":"60","author":"KS Kendler","year":"2003","unstructured":"Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA (2003) Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety. Arch Gen Psychiatry 60(8):789\u2013796","journal-title":"Arch Gen Psychiatry"},{"issue":"5","key":"5376_CR79","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.3390\/biomedicines10051005","volume":"10","author":"MT Lee","year":"2022","unstructured":"Lee MT, Peng WH, Kan HW, Wu CC, Wang DW, Ho YC (2022) Neurobiology of depression: chronic stress alters the glutamatergic system in the brain\u2014focusing on AMPA receptor. Biomedicines 10(5):1005","journal-title":"Biomedicines"},{"key":"5376_CR80","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.02143","volume":"11","author":"A Shimba","year":"2020","unstructured":"Shimba A, Ikuta K (2020) Glucocorticoids regulate circadian rhythm of innate and adaptive immunity. Front Immunol 11:2143","journal-title":"Front Immunol"},{"issue":"6153","key":"5376_CR81","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1126\/science.1240636","volume":"341","author":"KD Nguyen","year":"2013","unstructured":"Nguyen KD, Fentress SJ, Qiu Y, Yun K, Cox JS, Chawla A (2013) Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes. Science. 341(6153):1483\u20138","journal-title":"Science."},{"issue":"4","key":"5376_CR82","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.4049\/jimmunol.164.4.1768","volume":"164","author":"D Franchimont","year":"2000","unstructured":"Franchimont D, Galon J, Gadina M, Visconti R, Zhou Y, Aringer M et al (2000) Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes. J Immunol 164(4):1768\u20131774","journal-title":"J Immunol"},{"issue":"4","key":"5376_CR83","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1096\/fj.06-7452com","volume":"21","author":"AC Liberman","year":"2007","unstructured":"Liberman AC, Refojo D, Druker J, Toscano M, Rein T, Holsboer F et al (2007) The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction. FASEB J 21(4):1177\u20131188","journal-title":"FASEB J"},{"issue":"5","key":"5376_CR84","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1007\/s10787-017-0418-0","volume":"26","author":"L Chen","year":"2018","unstructured":"Chen L, Jondal M, Yakimchuk K (2018) Regulatory effects of dexamethasone on NK and T cell immunity. Inflammopharmacology 26(5):1331\u20131338","journal-title":"Inflammopharmacology"},{"issue":"41","key":"5376_CR85","doi-asserted-by":"publisher","first-page":"17582","DOI":"10.1073\/pnas.0909733106","volume":"106","author":"AYL So","year":"2009","unstructured":"So AYL, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ (2009) Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci USA 106(41):17582\u201317587","journal-title":"Proc Natl Acad Sci USA"},{"issue":"12","key":"5376_CR86","doi-asserted-by":"publisher","first-page":"6161","DOI":"10.1093\/nar\/gkt307","volume":"41","author":"S Cheon","year":"2013","unstructured":"Cheon S, Park N, Cho S, Kim K (2013) Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm. Nucleic Acids Res 41(12):6161\u20136174","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"5376_CR87","doi-asserted-by":"publisher","first-page":"3799","DOI":"10.1210\/endo.141.10.7708","volume":"141","author":"IP Torra","year":"2000","unstructured":"Torra IP, Tsibulsky V, Delaunay F, Saladin R, Laudet V, Fruchart JC et al (2000) Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver. Endocrinology 141(10):3799\u20133806","journal-title":"Endocrinology"},{"key":"5376_CR88","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1146\/annurev-psych-010418-102936","volume":"70","author":"AJ Tomiyama","year":"2019","unstructured":"Tomiyama AJ (2019) Stress and obesity. Annu Rev Psychol 70:703\u2013718","journal-title":"Annu Rev Psychol"},{"issue":"2","key":"5376_CR89","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1017\/S0954422419000143","volume":"32","author":"N Michels","year":"2019","unstructured":"Michels N (2019) Biological underpinnings from psychosocial stress towards appetite and obesity during youth: research implications towards metagenomics, epigenomics and metabolomics. Nutr Res Rev 32(2):282\u2013293","journal-title":"Nutr Res Rev"},{"issue":"5","key":"5376_CR90","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/s41574-022-00635-0","volume":"18","author":"DS Ludwig","year":"2022","unstructured":"Ludwig DS, S\u00f8rensen TIA (2022) An integrated model of obesity pathogenesis that revisits causal direction. Nat Rev Endocrinol 18(5):261\u2013262","journal-title":"Nat Rev Endocrinol"},{"issue":"4","key":"5376_CR91","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.tjnut.2023.01.026","volume":"153","author":"H Zhang","year":"2023","unstructured":"Zhang H, Wang Z, Wang G, Song X, Qian Y, Liao Z et al (2023) Understanding the connection between gut homeostasis and psychological stress. J Nutr 153(4):924\u2013939","journal-title":"J Nutr"},{"issue":"120","key":"5376_CR92","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.physbeh.2013.08.010","volume":"15","author":"MS Tryon","year":"2013","unstructured":"Tryon MS, Carter CS, Decant R, Laugero KD (2013) Chronic stress exposure may affect the brain\u2019s response to high calorie food cues and predispose to obesogenic eating habits. Physiol Behav 15(120):233\u2013242","journal-title":"Physiol Behav"},{"issue":"6","key":"5376_CR93","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.3390\/nu15061366","volume":"15","author":"R Podg\u00f3rski","year":"2023","unstructured":"Podg\u00f3rski R, Galiniak S, Mazur A, Domin A (2023) The association of the hypothalamic-pituitary-adrenal axis with appetite regulation in children with fetal alcohol spectrum disorders (FASDs). Nutrients 15(6):1366","journal-title":"Nutrients"},{"issue":"1","key":"5376_CR94","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.cmet.2019.04.001","volume":"30","author":"CK Ip","year":"2019","unstructured":"Ip CK, Zhang L, Farzi A, Qi Y, Clarke I, Reed F et al (2019) Amygdala NPY circuits promote the development of accelerated obesity under chronic stress conditions. Cell Metab 30(1):111-128.e6","journal-title":"Cell Metab"},{"issue":"1","key":"5376_CR95","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.physbeh.2011.08.019","volume":"106","author":"A Danese","year":"2012","unstructured":"Danese A, McEwen BS (2012) Adverse childhood experiences, allostasis, allostatic load, and age-related disease. Physiol Behav 106(1):29\u201339","journal-title":"Physiol Behav"},{"issue":"1","key":"5376_CR96","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s13679-011-0006-3","volume":"1","author":"KA Scott","year":"2012","unstructured":"Scott KA, Melhorn SJ, Sakai RR (2012) Effects of chronic social stress on obesity. Curr Obes Rep. 1(1):16\u201325","journal-title":"Curr Obes Rep."},{"issue":"3","key":"5376_CR97","first-page":"255","volume":"38","author":"YHC Yau","year":"2013","unstructured":"Yau YHC, Potenza MN (2013) Stress and eating behaviors. Minerva Endocrinol. 38(3):255\u201367","journal-title":"Minerva Endocrinol."},{"issue":"2","key":"5376_CR98","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1017\/S1466252316000153","volume":"17","author":"W Geng","year":"2016","unstructured":"Geng W, Lin J (2016) Bacterial bile salt hydrolase: an intestinal microbiome target for enhanced animal health. Anim Health Res Rev. 17(2):148\u201358","journal-title":"Anim Health Res Rev."},{"issue":"6","key":"5376_CR99","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.3390\/microorganisms9061122","volume":"9","author":"M Bourgin","year":"2021","unstructured":"Bourgin M, Kriaa A, Mkaouar H, Mariaule V, Jablaoui A, Maguin E et al (2021) Bile salt hydrolases: at the crossroads of microbiota and human health. Microorganisms 9(6):1122","journal-title":"Microorganisms"},{"issue":"1","key":"5376_CR100","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/S1499-3872(14)60307-6","volume":"14","author":"B Stanimirov","year":"2015","unstructured":"Stanimirov B, Stankov K, Mikov M (2015) Bile acid signaling through farnesoid X and TGR5 receptors in hepatobiliary and intestinal diseases. Hepatobiliary Pancreat Dis Int 14(1):18\u201333","journal-title":"Hepatobiliary Pancreat Dis Int"},{"issue":"1","key":"5376_CR101","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.cmet.2019.04.001","volume":"30","author":"CK Ip","year":"2019","unstructured":"Ip CK, Zhang L, Farzi A, Qi Y, Clarke I, Reed F et al (2019) Amygdala NPY circuits promote the development of accelerated obesity under chronic stress conditions. Cell Metab 30(1):111-128.e6","journal-title":"Cell Metab"},{"issue":"7","key":"5376_CR102","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.biopsych.2014.05.018","volume":"77","author":"JK Kiecolt-Glaser","year":"2015","unstructured":"Kiecolt-Glaser JK, Habash DL, Fagundes CP, Andridge R, Peng J, Malarkey WB et al (2015) Daily stressors, past depression, and metabolic responses to high-fat meals: a novel path to obesity. Biol Psychiatry 77(7):653\u2013660","journal-title":"Biol Psychiatry"},{"key":"5376_CR103","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2020.103525","volume":"107","author":"MA van der Kooij","year":"2020","unstructured":"van der Kooij MA (2020) The impact of chronic stress on energy metabolism. Mol Cell Neurosci 107:103525","journal-title":"Mol Cell Neurosci"},{"issue":"33","key":"5376_CR104","doi-asserted-by":"publisher","first-page":"e2303015","DOI":"10.1002\/advs.202303015","volume":"10","author":"Z Chen","year":"2023","unstructured":"Chen Z, Lv M, Liang J, Yang K, Li F, Zhou Z et al (2023) Neuropeptide Y-mediated gut microbiota alterations aggravate postmenopausal osteoporosis. Adv Sci (Weinh) 10(33):e2303015","journal-title":"Adv Sci (Weinh)"},{"issue":"4","key":"5376_CR105","doi-asserted-by":"publisher","first-page":"3887","DOI":"10.3390\/ijms24043887","volume":"24","author":"K Pierzynowska","year":"2023","unstructured":"Pierzynowska K, Gaffke L, \u017babi\u0144ska M, Cyske Z, Rintz E, Wi\u015bniewska K et al (2023) Roles of the oxytocin receptor (OXTR) in human diseases. Int J Mol Sci 24(4):3887","journal-title":"Int J Mol Sci"},{"issue":"4","key":"5376_CR106","doi-asserted-by":"publisher","first-page":"623","DOI":"10.3390\/cells11040623","volume":"11","author":"G Colleluori","year":"2022","unstructured":"Colleluori G, Galli C, Severi I, Perugini J, Giordano A (2022) Early life stress, brain development, and obesity risk: is oxytocin the missing link? Cells 11(4):623","journal-title":"Cells"},{"key":"5376_CR107","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2020.105099","volume":"125","author":"E Falc\u00f3n","year":"2021","unstructured":"Falc\u00f3n E, Vald\u00e9s-Moreno M, Rodr\u00edguez C, Sanabrais-Jim\u00e9nez M, Hern\u00e1ndez-Mu\u00f1oz S, Camarena B et al (2021) Interaction between three stress-related gene polymorphisms and food addiction increases the risk to develop obesity in a sample of Mexican people attending a nutrition clinic. Psychoneuroendocrinology 125:105099","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"5376_CR108","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.neuropharm.2012.04.017","volume":"63","author":"J Maniam","year":"2012","unstructured":"Maniam J, Morris MJ (2012) The link between stress and feeding behaviour. Neuropharmacology 63(1):97\u2013110","journal-title":"Neuropharmacology"},{"issue":"7","key":"5376_CR109","doi-asserted-by":"publisher","first-page":"3344","DOI":"10.3390\/ijms22073344","volume":"22","author":"SV Seal","year":"2021","unstructured":"Seal SV, Turner JD (2021) The \u2018Jekyll and Hyde\u2019 of gluconeogenesis: early life adversity, later life stress, and metabolic disturbances. Int J Mol Sci 22(7):3344","journal-title":"Int J Mol Sci"},{"issue":"6","key":"5376_CR110","doi-asserted-by":"publisher","first-page":"2266","DOI":"10.1172\/JCI66062","volume":"129","author":"A Cui","year":"2019","unstructured":"Cui A, Fan H, Zhang Y, Zhang Y, Niu D, Liu S et al (2019) Dexamethasone-induced Kr\u00fcppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia. J Clin Invest 129(6):2266\u20132278","journal-title":"J Clin Invest"},{"issue":"10","key":"5376_CR111","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.2337\/diacare.15.10.1413","volume":"15","author":"RS Surwit","year":"1992","unstructured":"Surwit RS, Schneider MS, Feinglos MN (1992) Stress and diabetes mellitus. Diabetes Care 15(10):1413\u20131422","journal-title":"Diabetes Care"},{"issue":"3","key":"5376_CR112","doi-asserted-by":"publisher","first-page":"321","DOI":"10.2174\/1871530323666230803095118","volume":"24","author":"G Lisco","year":"2024","unstructured":"Lisco G, Giagulli VA, De Pergola G, Guastamacchia E, Jirillo E, Vitale E et al (2024) Chronic stress as a risk factor for type 2 diabetes: endocrine, metabolic,and immune implications. EMIDDT 24(3):321\u2013332","journal-title":"EMIDDT"},{"issue":"7","key":"5376_CR113","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.tem.2016.04.007","volume":"27","author":"M Razzoli","year":"2016","unstructured":"Razzoli M, Bartolomucci A (2016) The dichotomous effect of chronic stress on obesity. Trends Endocrinol Metab 27(7):504\u2013515","journal-title":"Trends Endocrinol Metab"},{"issue":"3","key":"5376_CR114","doi-asserted-by":"publisher","first-page":"C375","DOI":"10.1152\/ajpcell.00379.2020","volume":"320","author":"T Kawai","year":"2021","unstructured":"Kawai T, Autieri MV, Scalia R (2021) Adipose tissue inflammation and metabolic dysfunction in obesity. Am J Physiol Cell Physiol 320(3):C375\u2013C391","journal-title":"Am J Physiol Cell Physiol"},{"key":"5376_CR115","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s003930070014","volume":"59","author":"HO Besedovsky","year":"2000","unstructured":"Besedovsky HO, del Rey A (2000) The cytokine-HPA axis feed-back circuit. Z Rheumatol. 59:26\u201330","journal-title":"Z Rheumatol."},{"issue":"11\u201312","key":"5376_CR116","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.nut.2007.08.008","volume":"23","author":"SJ Torres","year":"2007","unstructured":"Torres SJ, Nowson CA (2007) Relationship between stress, eating behavior, and obesity. Nutrition 23(11\u201312):887\u2013894","journal-title":"Nutrition"},{"issue":"6","key":"5376_CR117","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1210\/endrev\/bnae016","volume":"45","author":"SA Clarke","year":"2024","unstructured":"Clarke SA, Eng PC, Comninos AN, Lazarus K, Choudhury S, Tsang C et al (2024) Current challenges and future directions in the assessment of glucocorticoid status. Endocr Rev 45(6):795\u2013817","journal-title":"Endocr Rev"},{"issue":"2","key":"5376_CR118","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1017\/S0029665112000092","volume":"71","author":"FP de Heredia","year":"2012","unstructured":"de Heredia FP, G\u00f3mez-Mart\u00ednez S, Marcos A (2012) Obesity, inflammation and the immune system. Proc Nutr Soc 71(2):332\u2013338","journal-title":"Proc Nutr Soc"},{"issue":"1","key":"5376_CR119","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1152\/physrev.00021.2023","volume":"104","author":"GJ Martinez","year":"2024","unstructured":"Martinez GJ, Appleton M, Kipp ZA, Loria AS, Min B, Hinds TD (2024) Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries. Physiol Rev 104(1):473\u2013532","journal-title":"Physiol Rev"},{"issue":"9","key":"5376_CR120","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/nrendo.2017.64","volume":"13","author":"RA Hackett","year":"2017","unstructured":"Hackett RA, Steptoe A (2017) Type 2 diabetes mellitus and psychological stress - a modifiable risk factor. Nat Rev Endocrinol 13(9):547\u2013560","journal-title":"Nat Rev Endocrinol"},{"issue":"2","key":"5376_CR121","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1210\/jc.2015-2853","volume":"101","author":"RA Hackett","year":"2016","unstructured":"Hackett RA, Kivim\u00e4ki M, Kumari M, Steptoe A (2016) Diurnal cortisol patterns, future diabetes, and impaired glucose metabolism in the Whitehall II cohort study. J Clin Endocrinol Metab 101(2):619\u2013625","journal-title":"J Clin Endocrinol Metab"},{"key":"5376_CR122","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.yfrne.2018.03.001","volume":"49","author":"ES Epel","year":"2018","unstructured":"Epel ES, Crosswell AD, Mayer SE, Prather AA, Slavich GM, Puterman E et al (2018) More than a feeling: a unified view of stress measurement for population science. Front Neuroendocrinol 49:146\u2013169","journal-title":"Front Neuroendocrinol"},{"issue":"3","key":"5376_CR123","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1037\/0033-2909.130.3.355","volume":"130","author":"SS Dickerson","year":"2004","unstructured":"Dickerson SS, Kemeny ME (2004) Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychol Bull 130(3):355\u2013391","journal-title":"Psychol Bull"},{"key":"5376_CR124","doi-asserted-by":"publisher","first-page":"37","DOI":"10.3389\/fendo.2016.00037","volume":"7","author":"R Dumbell","year":"2016","unstructured":"Dumbell R, Matveeva O, Oster H (2016) Circadian clocks, stress, and immunity. Front Endocrinol (Lausanne) 7:37","journal-title":"Front Endocrinol (Lausanne)"},{"key":"5376_CR125","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ynstr.2016.09.001","volume":"6","author":"CE Koch","year":"2017","unstructured":"Koch CE, Leinweber B, Drengberg BC, Blaum C, Oster H (2017) Interaction between circadian rhythms and stress. Neurobiol Stress 6:57\u201367","journal-title":"Neurobiol Stress"},{"issue":"1","key":"5376_CR126","doi-asserted-by":"publisher","first-page":"R13","DOI":"10.1530\/JOE-20-0124","volume":"247","author":"H Oster","year":"2020","unstructured":"Oster H (2020) The interplay between stress, circadian clocks, and energy metabolism. J Endocrinol 247(1):R13-25","journal-title":"J Endocrinol"},{"issue":"1","key":"5376_CR127","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.psyneuen.2008.10.004","volume":"34","author":"BM Kudielka","year":"2009","unstructured":"Kudielka BM, Hellhammer DH, W\u00fcst S (2009) Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology 34(1):2\u201318","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"5376_CR128","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/s41574-018-0122-1","volume":"15","author":"DJ Stenvers","year":"2019","unstructured":"Stenvers DJ, Scheer FAJL, Schrauwen P, la Fleur SE, Kalsbeek A (2019) Circadian clocks and insulin resistance. Nat Rev Endocrinol 15(2):75\u201389","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"5376_CR129","doi-asserted-by":"publisher","first-page":"37","DOI":"10.4093\/dmj.2023.0193","volume":"48","author":"DY Lee","year":"2024","unstructured":"Lee DY, Jung I, Park SY, Yu JH, Seo JA, Kim KJ et al (2024) Attention to innate circadian rhythm and the impact of its disruption on diabetes. Diabetes Metab J 48(1):37\u201352","journal-title":"Diabetes Metab J"},{"key":"5376_CR130","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1156757","volume":"14","author":"A Hariri","year":"2023","unstructured":"Hariri A, Mirian M, Zarrabi A, Kohandel M, Amini-Pozveh M, Aref AR et al (2023) The circadian rhythm: an influential soundtrack in the diabetes story. Front Endocrinol (Lausanne) 14:1156757","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"5376_CR131","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nrn2647","volume":"10","author":"YM Ulrich-Lai","year":"2009","unstructured":"Ulrich-Lai YM, Herman JP (2009) Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci 10(6):397\u2013409","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"5376_CR132","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1093\/toxsci\/kfy129","volume":"164","author":"SJ Snow","year":"2018","unstructured":"Snow SJ, Henriquez AR, Costa DL, Kodavanti UP (2018) Neuroendocrine regulation of air pollution health effects: emerging insights. Toxicol Sci 164(1):9\u201320","journal-title":"Toxicol Sci"},{"issue":"3","key":"5376_CR133","doi-asserted-by":"publisher","first-page":"597","DOI":"10.3233\/JAD-190015","volume":"69","author":"EM Thomson","year":"2019","unstructured":"Thomson EM (2019) Air pollution, stress, and allostatic load: linking systemic and central nervous system impacts. J Alzheimers Dis 69(3):597\u2013614","journal-title":"J Alzheimers Dis"},{"issue":"7","key":"5376_CR134","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.4239\/wjd.v14.i7.1037","volume":"14","author":"EM Kruger","year":"2023","unstructured":"Kruger EM, Shehata SA, Toraih EA, Abdelghany AA, Fawzy MS (2023) Type 2 diabetes and thyroid cancer: synergized risk with rising air pollution. World J Diabetes 14(7):1037\u20131048","journal-title":"World J Diabetes"},{"key":"5376_CR135","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1146\/annurev-publhealth-031914-122921","volume":"36","author":"SJ Kelly","year":"2015","unstructured":"Kelly SJ, Ismail M (2015) Stress and type 2 diabetes: a review of how stress contributes to the development of type 2 diabetes. Annu Rev Public Health. 36:441\u201362","journal-title":"Annu Rev Public Health."},{"key":"5376_CR136","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2021.100972","volume":"65","author":"N Merabet","year":"2022","unstructured":"Merabet N, Lucassen PJ, Crielaard L, Stronks K, Quax R, Sloot PMA et al (2022) How exposure to chronic stress contributes to the development of type 2 diabetes: a complexity science approach. Front Neuroendocrinol 65:100972","journal-title":"Front Neuroendocrinol"},{"issue":"9","key":"5376_CR137","doi-asserted-by":"publisher","first-page":"e240222201413","DOI":"10.2174\/1573399818666220224140934","volume":"18","author":"Sunena","year":"2022","unstructured":"Sunena, Mishra DN (2022) Stress etiology of type 2 diabetes. Curr Diabetes Rev. 18(9):e240222201413","journal-title":"Curr Diabetes Rev."},{"issue":"23","key":"5376_CR138","doi-asserted-by":"publisher","first-page":"12846","DOI":"10.3390\/ijms222312846","volume":"22","author":"L Zhai","year":"2021","unstructured":"Zhai L, Wu J, Lam YY, Kwan HY, Bian ZX, Wong HLX (2021) Gut-Microbial metabolites, probiotics and their roles in type 2 diabetes. Int J Mol Sci 22(23):12846","journal-title":"Int J Mol Sci"},{"issue":"2","key":"5376_CR139","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1042\/CS20050243","volume":"110","author":"MB Jackson","year":"2006","unstructured":"Jackson MB, Ahima RS (2006) Neuroendocrine and metabolic effects of adipocyte-derived hormones. Clin Sci (Lond) 110(2):143\u2013152","journal-title":"Clin Sci (Lond)"},{"issue":"6","key":"5376_CR140","first-page":"546","volume":"16","author":"VK Sharma","year":"2020","unstructured":"Sharma VK, Singh TG (2020) Chronic stress and diabetes mellitus: interwoven pathologies. Curr Diabetes Rev 16(6):546\u2013556","journal-title":"Curr Diabetes Rev"},{"key":"5376_CR141","doi-asserted-by":"publisher","first-page":"e16029","DOI":"10.7717\/peerj.16029","volume":"11","author":"M Mao","year":"2023","unstructured":"Mao M, Deng Y, Wang L, Zhao G, Qi R, Gong H et al (2023) Chronic unpredictable mild stress promotes atherosclerosis via adipose tissue dysfunction in ApoE\u2212\/\u2212 mice. PeerJ. 11:e16029","journal-title":"PeerJ."},{"issue":"9","key":"5376_CR142","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1038\/s41573-021-00233-1","volume":"20","author":"HJ Forman","year":"2021","unstructured":"Forman HJ, Zhang H (2021) Targeting oxidative stress in disease: promise and limitations of antioxidant therapy. Nat Rev Drug Discov 20(9):689\u2013709","journal-title":"Nat Rev Drug Discov"},{"key":"5376_CR143","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.687868","volume":"9","author":"Y Lei","year":"2021","unstructured":"Lei Y, Cui Q, Yang G, Piao L, Inoue A, Wu H et al (2021) Statins mitigate stress-related vascular aging and atherosclerosis in apoE-deficient mice fed high fat-diet: the role of glucagon-like peptide-1\/adiponectin axis. Front Cell Dev Biol 9:687868","journal-title":"Front Cell Dev Biol"},{"issue":"5","key":"5376_CR144","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1161\/ATVBAHA.109.201582","volume":"30","author":"TK Rudolph","year":"2010","unstructured":"Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ et al (2010) Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 30(5):938\u2013945","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"9","key":"5376_CR145","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/S0165-6147(03)00233-5","volume":"24","author":"H Cai","year":"2003","unstructured":"Cai H, Griendling KK, Harrison DG (2003) The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 24(9):471\u2013478","journal-title":"Trends Pharmacol Sci"},{"issue":"6","key":"5376_CR146","doi-asserted-by":"publisher","first-page":"31130","DOI":"10.1038\/srep31130","volume":"5","author":"S Kumar","year":"2016","unstructured":"Kumar S, Chen M, Li Y, Wong FHS, Thiam CW, Hossain MZ et al (2016) Loss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE(\u2212\/\u2212) mice. Sci Rep 5(6):31130","journal-title":"Sci Rep"},{"issue":"10","key":"5376_CR147","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1042\/BJ20150844","volume":"473","author":"A Yurdagul","year":"2016","unstructured":"Yurdagul A, Finney AC, Woolard MD, Orr AW (2016) The arterial microenvironment: the where and why of atherosclerosis. Biochem J 473(10):1281\u20131295","journal-title":"Biochem J"},{"issue":"1","key":"5376_CR148","doi-asserted-by":"publisher","first-page":"89","DOI":"10.2741\/4378","volume":"21","author":"M Amin","year":"2016","unstructured":"Amin M, Pushpakumar S, Muradashvili N, Kundu S, Tyagi SC, Sen U (2016) Regulation and involvement of matrix metalloproteinases in vascular diseases. Front Biosci (Landmark Ed) 21(1):89\u2013118","journal-title":"Front Biosci (Landmark Ed)"},{"issue":"8","key":"5376_CR149","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1097\/HJH.0000000000002424","volume":"38","author":"X Meng","year":"2020","unstructured":"Meng X, Piao L, Wang H, Inoue A, Huang Z, Jiang H et al (2020) Deficiency of cysteinyl cathepsin K suppresses the development of experimental intimal hyperplasia in response to chronic stress. J Hypertens 38(8):1514\u20131524","journal-title":"J Hypertens"},{"issue":"6","key":"5376_CR150","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1172\/JCI200314915","volume":"111","author":"GK Sukhova","year":"2003","unstructured":"Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M et al (2003) Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest 111(6):897\u2013906","journal-title":"J Clin Invest"},{"issue":"1","key":"5376_CR151","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.105.561449","volume":"113","author":"E Lutgens","year":"2006","unstructured":"Lutgens E, Lutgens SPM, Faber BCG, Heeneman S, Gijbels MMJ, de Winther MPJ et al (2006) Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation. Circulation 113(1):98\u2013107","journal-title":"Circulation"},{"issue":"Pt B","key":"5376_CR152","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.neubiorev.2016.05.004","volume":"74","author":"EJ Brunner","year":"2017","unstructured":"Brunner EJ (2017) Social factors and cardiovascular morbidity. Neurosci Biobehav Rev 74(Pt B):260\u2013268","journal-title":"Neurosci Biobehav Rev"},{"issue":"Pt B","key":"5376_CR153","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.neubiorev.2016.10.011","volume":"74","author":"M Esler","year":"2017","unstructured":"Esler M (2017) Mental stress and human cardiovascular disease. Neurosci Biobehav Rev 74(Pt B):269\u2013276","journal-title":"Neurosci Biobehav Rev"},{"key":"5376_CR154","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.bbi.2015.08.007","volume":"50","author":"HM Lagraauw","year":"2015","unstructured":"Lagraauw HM, Kuiper J, Bot I (2015) Acute and chronic psychological stress as risk factors for cardiovascular disease: insights gained from epidemiological, clinical and experimental studies. Brain Behav Immun 50:18\u201330","journal-title":"Brain Behav Immun"},{"issue":"Pt B","key":"5376_CR155","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.neubiorev.2016.04.018","volume":"74","author":"SK Wood","year":"2017","unstructured":"Wood SK, Valentino RJ (2017) The brain norepinephrine system, stress and cardiovascular vulnerability. Neurosci Biobehav Rev 74(Pt B):393\u2013400","journal-title":"Neurosci Biobehav Rev"},{"issue":"10046","key":"5376_CR156","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/S0140-6736(16)30506-2","volume":"388","author":"MJ O\u2019Donnell","year":"2016","unstructured":"O\u2019Donnell MJ, Chin SL, Rangarajan S, Xavier D, Liu L, Zhang H et al (2016) Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. Lancet 388(10046):761\u2013775","journal-title":"Lancet"},{"issue":"9438","key":"5376_CR157","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1016\/S0140-6736(04)17019-0","volume":"364","author":"A Rosengren","year":"2004","unstructured":"Rosengren A, Hawken S, Ounpuu S, Sliwa K, Zubaid M, Almahmeed WA et al (2004) Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): case-control study. Lancet. 364(9438):953\u201362","journal-title":"Lancet."},{"issue":"9","key":"5376_CR158","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1016\/j.neubiorev.2012.07.001","volume":"36","author":"MN Hill","year":"2012","unstructured":"Hill MN, Hellemans KGC, Verma P, Gorzalka BB, Weinberg J (2012) Neurobiology of chronic mild stress: parallels to major depression. Neurosci Biobehav Rev 36(9):2085\u20132117","journal-title":"Neurosci Biobehav Rev"},{"issue":"Pt B","key":"5376_CR159","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.neubiorev.2016.04.023","volume":"74","author":"V Vaccarino","year":"2017","unstructured":"Vaccarino V, Bremner JD (2017) Behavioral, emotional and neurobiological determinants of coronary heart disease risk in women. Neurosci Biobehav Rev 74(Pt B):297\u2013309","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"5376_CR160","doi-asserted-by":"publisher","first-page":"e30","DOI":"10.1161\/STR.0000000000000113","volume":"48","author":"A Towfighi","year":"2017","unstructured":"Towfighi A, Ovbiagele B, El Husseini N, Hackett ML, Jorge RE, Kissela BM et al (2017) Poststroke depression: a scientific statement for healthcare professionals from the American Heart Association\/American Stroke Association. Stroke 48(2):e30-43","journal-title":"Stroke"},{"key":"5376_CR161","first-page":"862978","volume":"2013","author":"F Bartoli","year":"2013","unstructured":"Bartoli F, Lillia N, Lax A, Crocamo C, Mantero V, Carr\u00e0 G et al (2013) Depression after stroke and risk of mortality: a systematic review and meta-analysis. Stroke Res Treat 2013:862978","journal-title":"Stroke Res Treat"},{"issue":"Pt B","key":"5376_CR162","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.neubiorev.2016.07.003","volume":"74","author":"BWJH Penninx","year":"2017","unstructured":"Penninx BWJH (2017) Depression and cardiovascular disease: epidemiological evidence on their linking mechanisms. Neurosci Biobehav Rev 74(Pt B):277\u2013286","journal-title":"Neurosci Biobehav Rev"},{"issue":"1\u20132","key":"5376_CR163","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jad.2011.03.027","volume":"133","author":"BWJH Penninx","year":"2011","unstructured":"Penninx BWJH, Nolen WA, Lamers F, Zitman FG, Smit JH, Spinhoven P et al (2011) Two-year course of depressive and anxiety disorders: results from the Netherlands study of depression and anxiety (NESDA). J Affect Disord 133(1\u20132):76\u201385","journal-title":"J Affect Disord"},{"key":"5376_CR164","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02031","volume":"9","author":"M Fioranelli","year":"2018","unstructured":"Fioranelli M, Bottaccioli AG, Bottaccioli F, Bianchi M, Rovesti M, Roccia MG (2018) Stress and inflammation in coronary artery disease: a review psychoneuroendocrineimmunology-based. Front Immunol 9:2031","journal-title":"Front Immunol"},{"issue":"3","key":"5376_CR165","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.jad.2011.08.003","volume":"139","author":"Y Liu","year":"2012","unstructured":"Liu Y, Ho RCM, Mak A (2012) Interleukin (IL)-6, tumour necrosis factor alpha (TNF-\u03b1) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression. J Affect Disord 139(3):230\u2013239","journal-title":"J Affect Disord"},{"key":"5376_CR166","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1146\/annurev-publhealth-031912-114452","volume":"34","author":"A Steptoe","year":"2013","unstructured":"Steptoe A, Kivim\u00e4ki M (2013) Stress and cardiovascular disease: an update on current knowledge. Annu Rev Public Health 34:337\u2013354","journal-title":"Annu Rev Public Health"},{"issue":"15","key":"5376_CR167","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s12872-015-0036-y","volume":"12","author":"HWJ van Marwijk","year":"2015","unstructured":"van Marwijk HWJ, van der Kooy KG, Stehouwer CDA, Beekman ATF, van Hout HPJ (2015) Depression increases the onset of cardiovascular disease over and above other determinants in older primary care patients, a cohort study. BMC Cardiovasc Disord 12(15):40","journal-title":"BMC Cardiovasc Disord"},{"issue":"6","key":"5376_CR168","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1038\/nrcardio.2012.45","volume":"9","author":"A Steptoe","year":"2012","unstructured":"Steptoe A, Kivim\u00e4ki M (2012) Stress and cardiovascular disease. Nat Rev Cardiol 9(6):360\u2013370","journal-title":"Nat Rev Cardiol"},{"issue":"4","key":"5376_CR169","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1038\/nrcardio.2017.189","volume":"15","author":"M Kivim\u00e4ki","year":"2018","unstructured":"Kivim\u00e4ki M, Steptoe A (2018) Effects of stress on the development and progression of cardiovascular disease. Nat Rev Cardiol 15(4):215\u2013229","journal-title":"Nat Rev Cardiol"},{"issue":"9","key":"5376_CR170","doi-asserted-by":"publisher","first-page":"628","DOI":"10.3390\/brainsci10090628","volume":"10","author":"HR Aboelwafa","year":"2020","unstructured":"Aboelwafa HR, El-Kott AF, Abd-Ella EM, Yousef HN (2020) The possible neuroprotective effect of Silymarin against aluminum chloride-prompted Alzheimer\u2019s-like disease in rats. Brain Sci. 10(9):628","journal-title":"Brain Sci."},{"issue":"9533","key":"5376_CR171","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0140-6736(06)69113-7","volume":"368","author":"K Blennow","year":"2006","unstructured":"Blennow K, de Leon MJ, Zetterberg H (2006) Alzheimer\u2019s disease. Lancet 368(9533):387\u2013403","journal-title":"Lancet"},{"issue":"3","key":"5376_CR172","doi-asserted-by":"publisher","first-page":"356","DOI":"10.2174\/09298673113206660258","volume":"21","author":"M Pohanka","year":"2014","unstructured":"Pohanka M (2014) Alzheimer\u00b4s disease and oxidative stress: a review. Curr Med Chem 21(3):356\u2013364","journal-title":"Curr Med Chem"},{"issue":"4","key":"5376_CR173","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1002\/bab.2216","volume":"69","author":"S Mohammadi","year":"2022","unstructured":"Mohammadi S, Zandi M, Dousti Kataj P, Karimi Zandi L (2022) Chronic stress and Alzheimer\u2019s disease. Biotechnol Appl Biochem 69(4):1451\u20131458","journal-title":"Biotechnol Appl Biochem"},{"issue":"10","key":"5376_CR174","doi-asserted-by":"publisher","first-page":"2491","DOI":"10.1111\/j.1460-9568.2004.03717.x","volume":"20","author":"EYH Wong","year":"2004","unstructured":"Wong EYH, Herbert J (2004) The corticoid environment: a determining factor for neural progenitors\u2019 survival in the adult hippocampus. Eur J Neurosci 20(10):2491\u20132498","journal-title":"Eur J Neurosci"},{"issue":"341","key":"5376_CR175","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.bbr.2017.12.025","volume":"2","author":"E Jesulola","year":"2018","unstructured":"Jesulola E, Micalos P, Baguley IJ (2018) Understanding the pathophysiology of depression: from monoamines to the neurogenesis hypothesis model\u2014are we there yet? Behav Brain Res 2(341):79\u201390","journal-title":"Behav Brain Res"},{"issue":"1","key":"5376_CR176","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.psc.2011.12.001","volume":"35","author":"RV Saveanu","year":"2012","unstructured":"Saveanu RV, Nemeroff CB (2012) Etiology of depression: genetic and environmental factors. Psychiatr Clin North Am 35(1):51\u201371","journal-title":"Psychiatr Clin North Am"},{"issue":"9","key":"5376_CR177","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.tins.2008.06.006","volume":"31","author":"CM Pariante","year":"2008","unstructured":"Pariante CM, Lightman SL (2008) The HPA axis in major depression: classical theories and new developments. Trends Neurosci 31(9):464\u2013468","journal-title":"Trends Neurosci"},{"key":"5376_CR178","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ynstr.2018.04.002","volume":"8","author":"NJ Justice","year":"2018","unstructured":"Justice NJ (2018) The relationship between stress and Alzheimer\u2019s disease. Neurobiol Stress 8:127\u2013133","journal-title":"Neurobiol Stress"},{"issue":"35","key":"5376_CR179","doi-asserted-by":"publisher","first-page":"9047","DOI":"10.1523\/JNEUROSCI.2797-06.2006","volume":"26","author":"KN Green","year":"2006","unstructured":"Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM (2006) Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer\u2019s disease. J Neurosci 26(35):9047\u20139056","journal-title":"J Neurosci"},{"key":"5376_CR180","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.yfrne.2015.12.001","volume":"41","author":"J Herbert","year":"2016","unstructured":"Herbert J, Lucassen PJ (2016) Depression as a risk factor for Alzheimer\u2019s disease: genes, steroids, cytokines and neurogenesis - What do we need to know? Front Neuroendocrinol 41:153\u2013171","journal-title":"Front Neuroendocrinol"},{"issue":"5","key":"5376_CR181","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1176\/ajp.140.5.586","volume":"140","author":"DL Evans","year":"1983","unstructured":"Evans DL, Burnett GB, Nemeroff CB (1983) The dexamethasone suppression test in the clinical setting. Am J Psychiatry 140(5):586\u2013589","journal-title":"Am J Psychiatry"},{"issue":"2","key":"5376_CR182","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.biopsych.2020.11.007","volume":"90","author":"JW Koo","year":"2021","unstructured":"Koo JW, Wohleb ES (2021) How stress shapes neuroimmune function: implications for the neurobiology of psychiatric disorders. Biol Psychiatry 90(2):74\u201384","journal-title":"Biol Psychiatry"},{"issue":"4","key":"5376_CR183","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/S0893-133X(99)00134-7","volume":"22","author":"S Lanquillon","year":"2000","unstructured":"Lanquillon S, Krieg JC, Bening-Abu-Shach U, Vedder H (2000) Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology 22(4):370\u2013379","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"5376_CR184","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.pnpbp.2004.11.003","volume":"29","author":"OJG Schiepers","year":"2005","unstructured":"Schiepers OJG, Wichers MC, Maes M (2005) Cytokines and major depression. Prog Neuropsychopharmacol Biol Psychiatry 29(2):201\u2013217","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"6","key":"5376_CR185","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197267","volume":"13","author":"W Zou","year":"2018","unstructured":"Zou W, Feng R, Yang Y (2018) Changes in the serum levels of inflammatory cytokines in antidepressant drug-na\u00efve patients with major depression. PLoS ONE 13(6):e0197267","journal-title":"PLoS ONE"},{"issue":"1","key":"5376_CR186","first-page":"31","volume":"11","author":"N M\u00fcller","year":"2010","unstructured":"M\u00fcller N (2010) COX-2 inhibitors as antidepressants and antipsychotics: clinical evidence. Curr Opin Investig Drugs 11(1):31\u201342","journal-title":"Curr Opin Investig Drugs"},{"issue":"12","key":"5376_CR187","doi-asserted-by":"publisher","first-page":"2245","DOI":"10.1016\/j.bbadis.2013.07.022","volume":"1832","author":"S Wuwongse","year":"2013","unstructured":"Wuwongse S, Cheng SSY, Wong GTH, Hung CHL, Zhang NQ, Ho YS et al (2013) Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: implications for depression and Alzheimer\u2019s disease. Biochim Biophys Acta 1832(12):2245\u20132256","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"5376_CR188","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1038\/s41398-020-0839-1","volume":"10","author":"FS Dafsari","year":"2020","unstructured":"Dafsari FS, Jessen F (2020) Depression-an underrecognized target for prevention of dementia in Alzheimer\u2019s disease. Transl Psychiatry 10(1):160","journal-title":"Transl Psychiatry"},{"issue":"3","key":"5376_CR189","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.cmet.2023.02.003","volume":"35","author":"NWS Chew","year":"2023","unstructured":"Chew NWS, Ng CH, Tan DJH, Kong G, Lin C, Chin YH et al (2023) The global burden of metabolic disease: data from 2000 to 2019. Cell Metab 35(3):414-428.e3","journal-title":"Cell Metab"},{"key":"5376_CR190","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.ejphar.2018.07.039","volume":"834","author":"V Micale","year":"2018","unstructured":"Micale V, Drago F (2018) Endocannabinoid system, stress and HPA axis. Eur J Pharmacol. 834:230\u20139","journal-title":"Eur J Pharmacol."},{"issue":"5","key":"5376_CR191","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1111\/obr.12019","volume":"14","author":"HKJ Gonnissen","year":"2013","unstructured":"Gonnissen HKJ, Hulshof T, Westerterp-Plantenga MS (2013) Chronobiology, endocrinology, and energy- and food-reward homeostasis. Obes Rev 14(5):405\u2013416","journal-title":"Obes Rev"},{"issue":"9","key":"5376_CR192","doi-asserted-by":"publisher","first-page":"7910","DOI":"10.3390\/ijms24097910","volume":"24","author":"E Gusev","year":"2023","unstructured":"Gusev E, Sarapultsev A (2023) Atherosclerosis and inflammation: insights from the theory of general pathological processes. Int J Mol Sci 24(9):7910","journal-title":"Int J Mol Sci"},{"issue":"966","key":"5376_CR193","doi-asserted-by":"publisher","first-page":"176338","DOI":"10.1016\/j.ejphar.2024.176338","volume":"5","author":"A Attiq","year":"2024","unstructured":"Attiq A, Afzal S, Ahmad W, Kandeel M (2024) Hegemony of inflammation in atherosclerosis and coronary artery disease. Eur J Pharmacol 5(966):176338","journal-title":"Eur J Pharmacol"},{"issue":"14","key":"5376_CR194","doi-asserted-by":"publisher","first-page":"2880","DOI":"10.1093\/cvr\/cvab316","volume":"118","author":"T M\u00fcnzel","year":"2022","unstructured":"M\u00fcnzel T, Hahad O, S\u00f8rensen M, Lelieveld J, Duerr GD, Nieuwenhuijsen M et al (2022) Environmental risk factors and cardiovascular diseases: a comprehensive expert review. Cardiovasc Res 118(14):2880\u20132902","journal-title":"Cardiovasc Res"},{"issue":"10","key":"5376_CR195","doi-asserted-by":"publisher","first-page":"e763","DOI":"10.1161\/CIR.0000000000000947","volume":"143","author":"GN Levine","year":"2021","unstructured":"Levine GN, Cohen BE, Commodore-Mensah Y, Fleury J, Huffman JC, Khalid U et al (2021) Psychological health, well-being, and the mind-heart-body connection: a scientific statement from the American Heart Association. Circulation 143(10):e763\u2013e783","journal-title":"Circulation"},{"key":"5376_CR196","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jpsychires.2016.07.019","volume":"82","author":"JR Kelly","year":"2016","unstructured":"Kelly JR, Borre Y, O\u2019Brien C, Patterson E, El Aidy S, Deane J et al (2016) Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat. J Psychiatr Res. 82:109\u201318","journal-title":"J Psychiatr Res."},{"issue":"6","key":"5376_CR197","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1038\/mp.2016.44","volume":"21","author":"P Zheng","year":"2016","unstructured":"Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu X et al (2016) Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host\u2019s metabolism. Mol Psychiatry 21(6):786\u2013796","journal-title":"Mol Psychiatry"},{"issue":"4","key":"5376_CR198","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/s41564-018-0337-x","volume":"4","author":"M Valles-Colomer","year":"2019","unstructured":"Valles-Colomer M, Falony G, Darzi Y, Tigchelaar EF, Wang J, Tito RY et al (2019) The neuroactive potential of the human gut microbiota in quality of life and depression. Nat Microbiol 4(4):623\u2013632","journal-title":"Nat Microbiol"},{"issue":"1","key":"5376_CR199","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s00213-010-2010-9","volume":"214","author":"SM O\u2019Mahony","year":"2011","unstructured":"O\u2019Mahony SM, Hyland NP, Dinan TG, Cryan JF (2011) Maternal separation as a model of brain-gut axis dysfunction. Psychopharmacology 214(1):71\u201388","journal-title":"Psychopharmacology"},{"issue":"2","key":"5376_CR200","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1002\/(SICI)1098-2302(199909)35:2<146::AID-DEV7>3.0.CO;2-G","volume":"35","author":"MT Bailey","year":"1999","unstructured":"Bailey MT, Coe CL (1999) Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev Psychobiol 35(2):146\u2013155","journal-title":"Dev Psychobiol"},{"issue":"3","key":"5376_CR201","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.biopsych.2008.06.026","volume":"65","author":"SM O\u2019Mahony","year":"2009","unstructured":"O\u2019Mahony SM, Marchesi JR, Scully P, Codling C, Ceolho AM, Quigley EMM et al (2009) Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry 65(3):263\u2013267","journal-title":"Biol Psychiatry"},{"issue":"3","key":"5376_CR202","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.bbi.2010.10.023","volume":"25","author":"MT Bailey","year":"2011","unstructured":"Bailey MT, Dowd SE, Galley JD, Hufnagle AR, Allen RG, Lyte M (2011) Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav Immun 25(3):397\u2013407","journal-title":"Brain Behav Immun"},{"issue":"1","key":"5376_CR203","doi-asserted-by":"publisher","first-page":"3950","DOI":"10.1038\/s41598-020-60862-1","volume":"10","author":"M Xu","year":"2020","unstructured":"Xu M, Wang C, Krolick KN, Shi H, Zhu J (2020) Difference in post-stress recovery of the gut microbiome and its altered metabolism after chronic adolescent stress in rats. Sci Rep 10(1):3950","journal-title":"Sci Rep"},{"issue":"14","key":"5376_CR204","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/1471-2180-14-189","volume":"15","author":"JD Galley","year":"2014","unstructured":"Galley JD, Nelson MC, Yu Z, Dowd SE, Walter J, Kumar PS et al (2014) Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota. BMC Microbiol 15(14):189","journal-title":"BMC Microbiol"},{"issue":"60","key":"5376_CR205","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1146\/annurev-pharmtox-010919-023628","volume":"6","author":"C Long-Smith","year":"2020","unstructured":"Long-Smith C, O\u2019Riordan KJ, Clarke G, Stanton C, Dinan TG, Cryan JF (2020) Microbiota-gut-brain axis: new therapeutic opportunities. Annu Rev Pharmacol Toxicol 6(60):477\u2013502","journal-title":"Annu Rev Pharmacol Toxicol"},{"issue":"5","key":"5376_CR206","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1053\/j.gastro.2020.10.066","volume":"160","author":"KG Margolis","year":"2021","unstructured":"Margolis KG, Cryan JF, Mayer EA (2021) The microbiota-gut-brain axis: from motility to mood. Gastroenterology 160(5):1486\u20131501","journal-title":"Gastroenterology"},{"issue":"5","key":"5376_CR207","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/nrgastro.2009.35","volume":"6","author":"SH Rhee","year":"2009","unstructured":"Rhee SH, Pothoulakis C, Mayer EA (2009) Principles and clinical implications of the brain-gut-enteric microbiota axis. Nat Rev Gastroenterol Hepatol 6(5):306\u2013314","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"11","key":"5376_CR208","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1038\/nrmicro2876","volume":"10","author":"SM Collins","year":"2012","unstructured":"Collins SM, Surette M, Bercik P (2012) The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol 10(11):735\u2013742","journal-title":"Nat Rev Microbiol"},{"issue":"4","key":"5376_CR209","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1152\/physrev.00018.2018","volume":"99","author":"JF Cryan","year":"2019","unstructured":"Cryan JF, O\u2019Riordan KJ, Cowan CSM, Sandhu KV, Bastiaanssen TFS, Boehme M et al (2019) The microbiota-gut-brain axis. Physiol Rev 99(4):1877\u20132013","journal-title":"Physiol Rev"},{"issue":"10","key":"5376_CR210","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1038\/nrn3346","volume":"13","author":"JF Cryan","year":"2012","unstructured":"Cryan JF, Dinan TG (2012) Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 13(10):701\u2013712","journal-title":"Nat Rev Neurosci"},{"issue":"7","key":"5376_CR211","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.it.2016.05.003","volume":"37","author":"KG Margolis","year":"2016","unstructured":"Margolis KG, Gershon MD, Bogunovic M (2016) Cellular organization of neuroimmune interactions in the gastrointestinal tract. Trends Immunol 37(7):487\u2013501","journal-title":"Trends Immunol"},{"issue":"9","key":"5376_CR212","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/nrgastro.2016.107","volume":"13","author":"M Rao","year":"2016","unstructured":"Rao M, Gershon MD (2016) The bowel and beyond: the enteric nervous system in neurological disorders. Nat Rev Gastroenterol Hepatol 13(9):517\u2013528","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"5376_CR213","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00049","volume":"12","author":"B Bonaz","year":"2018","unstructured":"Bonaz B, Bazin T, Pellissier S (2018) The vagus nerve at the interface of the microbiota-gut-brain axis. Front Neurosci 12:49","journal-title":"Front Neurosci"},{"issue":"8","key":"5376_CR214","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nrn3071","volume":"12","author":"EA Mayer","year":"2011","unstructured":"Mayer EA (2011) Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci 12(8):453\u2013466","journal-title":"Nat Rev Neurosci"},{"issue":"10","key":"5376_CR215","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1038\/ni.2967","volume":"15","author":"CC Bain","year":"2014","unstructured":"Bain CC, Bravo-Blas A, Scott CL, Perdiguero EG, Geissmann F, Henri S et al (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nat Immunol 15(10):929\u2013937","journal-title":"Nat Immunol"},{"issue":"1","key":"5376_CR216","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s40168-022-01458-x","volume":"11","author":"Y Pi","year":"2023","unstructured":"Pi Y, Wu Y, Zhang X, Lu D, Han D, Zhao J et al (2023) Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization. Microbiome 11(1):19","journal-title":"Microbiome"},{"issue":"11","key":"5376_CR217","doi-asserted-by":"publisher","first-page":"2447","DOI":"10.1038\/s41418-019-0312-y","volume":"26","author":"R Li","year":"2019","unstructured":"Li R, Zhou R, Wang H, Li W, Pan M, Yao X et al (2019) Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer. Cell Death Differ 26(11):2447\u20132463","journal-title":"Cell Death Differ"},{"issue":"5","key":"5376_CR218","doi-asserted-by":"publisher","first-page":"16148","DOI":"10.1038\/srep16148","volume":"6","author":"C Nastasi","year":"2015","unstructured":"Nastasi C, Candela M, Bonefeld CM, Geisler C, Hansen M, Krejsgaard T et al (2015) The effect of short-chain fatty acids on human monocyte-derived dendritic cells. Sci Rep 6(5):16148","journal-title":"Sci Rep"},{"issue":"3","key":"5376_CR219","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1124\/mol.62.3.722","volume":"62","author":"CE Ruby","year":"2002","unstructured":"Ruby CE, Leid M, Kerkvliet NI (2002) 2,3,7,8-tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-alpha and anti-CD40-induced activation of NF-kappaB\/Rel in dendritic cells: p50 homodimer activation is not affected. Mol Pharmacol 62(3):722\u2013728","journal-title":"Mol Pharmacol"},{"issue":"1","key":"5376_CR220","doi-asserted-by":"publisher","first-page":"4457","DOI":"10.1038\/s41467-020-18262-6","volume":"11","author":"W Yang","year":"2020","unstructured":"Yang W, Yu T, Huang X, Bilotta AJ, Xu L, Lu Y et al (2020) Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 11(1):4457","journal-title":"Nat Commun."},{"issue":"1","key":"5376_CR221","doi-asserted-by":"publisher","first-page":"264","DOI":"10.4049\/jimmunol.1501789","volume":"196","author":"AK Ehrlich","year":"2016","unstructured":"Ehrlich AK, Pennington JM, Wang X, Rohlman D, Punj S, L\u00f6hr CV et al (2016) Activation of the aryl hydrocarbon receptor by 10-Cl-BBQ prevents insulitis and effector T cell development independently of Foxp3+ regulatory T cells in nonobese diabetic mice. J Immunol 196(1):264\u2013273","journal-title":"J Immunol"},{"issue":"7","key":"5376_CR222","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1111\/all.14223","volume":"75","author":"M Giovannini","year":"2020","unstructured":"Giovannini M, Lodi L, Ricci S (2020) T-cell immunomodulation by bile acid metabolites. Allergy 75(7):1833\u20131834","journal-title":"Allergy"},{"issue":"3","key":"5376_CR223","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.4049\/jimmunol.179.3.1634","volume":"179","author":"S Chen","year":"2007","unstructured":"Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PE (2007) Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation. J Immunol 179(3):1634\u20131647","journal-title":"J Immunol"},{"issue":"3","key":"5376_CR224","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1271\/bbb.80733","volume":"73","author":"T Ishikawa","year":"2009","unstructured":"Ishikawa T, Nanjo F (2009) Dietary cycloinulooligosaccharides enhance intestinal immunoglobulin A production in mice. Biosci Biotechnol Biochem 73(3):677\u2013682","journal-title":"Biosci Biotechnol Biochem"},{"issue":"4","key":"5376_CR225","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1084\/jem.20020121","volume":"196","author":"G Frumento","year":"2002","unstructured":"Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB (2002) Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J Exp Med 196(4):459\u2013468","journal-title":"J Exp Med"},{"issue":"13","key":"5376_CR226","doi-asserted-by":"publisher","first-page":"4118","DOI":"10.1182\/blood-2006-03-006700","volume":"108","author":"M Della Chiesa","year":"2006","unstructured":"Della Chiesa M, Carlomagno S, Frumento G, Balsamo M, Cantoni C, Conte R et al (2006) The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. Blood 108(13):4118\u20134125","journal-title":"Blood"},{"issue":"3","key":"5376_CR227","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.cell.2017.07.008","volume":"170","author":"T Yu","year":"2017","unstructured":"Yu T, Guo F, Yu Y, Sun T, Ma D, Han J et al (2017) Fusobacterium nucleatum promotes chemoresistance to colorectal cancer by modulating autophagy. Cell 170(3):548-563.e16","journal-title":"Cell"},{"issue":"6","key":"5376_CR228","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1053\/j.gastro.2014.01.001","volume":"146","author":"MT Abreu","year":"2014","unstructured":"Abreu MT, Peek RM (2014) Gastrointestinal malignancy and the microbiome. Gastroenterology 146(6):1534-1546.e3","journal-title":"Gastroenterology"},{"issue":"4","key":"5376_CR229","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.4049\/jimmunol.179.4.2501","volume":"179","author":"H Liu","year":"2007","unstructured":"Liu H, Redline RW, Han YW (2007) Fusobacterium nucleatum induces fetal death in mice via stimulation of TLR4-mediated placental inflammatory response. J Immunol 179(4):2501\u20132508","journal-title":"J Immunol"},{"issue":"2","key":"5376_CR230","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/nm.3444","volume":"20","author":"A Trompette","year":"2014","unstructured":"Trompette A, Gollwitzer ES, Yadava K, Sichelstiel AK, Sprenger N, Ngom-Bru C et al (2014) Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med 20(2):159\u2013166","journal-title":"Nat Med"},{"issue":"9","key":"5376_CR231","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/nchembio.1864","volume":"11","author":"AS Devlin","year":"2015","unstructured":"Devlin AS, Fischbach MA (2015) A biosynthetic pathway for a prominent class of microbiota-derived bile acids. Nat Chem Biol 11(9):685\u2013690","journal-title":"Nat Chem Biol"},{"issue":"7885","key":"5376_CR232","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1038\/s41586-021-03832-5","volume":"599","author":"Y Sato","year":"2021","unstructured":"Sato Y, Atarashi K, Plichta DR, Arai Y, Sasajima S, Kearney SM et al (2021) Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians. Nature 599(7885):458\u2013464","journal-title":"Nature"},{"issue":"4","key":"5376_CR233","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1021\/acs.jafc.7b04994","volume":"66","author":"X Si","year":"2018","unstructured":"Si X, Shang W, Zhou Z, Shui G, Lam SM, Blanchard C et al (2018) Gamma-aminobutyric acid enriched rice bran diet attenuates insulin resistance and balances energy expenditure via modification of gut microbiota and short-chain fatty acids. J Agric Food Chem 66(4):881\u2013890","journal-title":"J Agric Food Chem"},{"issue":"2","key":"5376_CR234","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.immuni.2019.06.002","volume":"51","author":"A Bachem","year":"2019","unstructured":"Bachem A, Makhlouf C, Binger KJ, de Souza DP, Tull D, Hochheiser K et al (2019) Microbiota-derived short-chain fatty acids promote the memory potential of antigen-activated CD8+ T cells. Immunity 51(2):285-297.e5","journal-title":"Immunity"},{"issue":"8","key":"5376_CR235","doi-asserted-by":"publisher","first-page":"4229","DOI":"10.3390\/ijms22084229","volume":"22","author":"P Ergang","year":"2021","unstructured":"Ergang P, Vagnerov\u00e1 K, Hermanov\u00e1 P, Vodi\u010dka M, J\u00e1gr M, \u0160r\u016ftkov\u00e1 D et al (2021) The gut microbiota affects corticosterone production in the murine small intestine. Int J Mol Sci 22(8):4229","journal-title":"Int J Mol Sci"},{"issue":"6123","key":"5376_CR236","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1126\/science.1233521","volume":"339","author":"JGM Markle","year":"2013","unstructured":"Markle JGM, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U et al (2013) Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science 339(6123):1084\u20131088","journal-title":"Science"},{"issue":"11","key":"5376_CR237","doi-asserted-by":"publisher","first-page":"e867","DOI":"10.1016\/S2666-5247(22)00184-7","volume":"3","author":"CGM Alcazar","year":"2022","unstructured":"Alcazar CGM, Paes VM, Shao Y, Oesser C, Miltz A, Lawley TD et al (2022) The association between early-life gut microbiota and childhood respiratory diseases: a systematic review. Lancet Microbe 3(11):e867\u2013e880","journal-title":"Lancet Microbe"},{"issue":"4","key":"5376_CR238","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2017.1373208","volume":"5","author":"T Takiishi","year":"2017","unstructured":"Takiishi T, Fenero CIM, C\u00e2mara NOS (2017) Intestinal barrier and gut microbiota: shaping our immune responses throughout life. Tissue Barriers 5(4):e1373208","journal-title":"Tissue Barriers"},{"issue":"2","key":"5376_CR239","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.chom.2023.12.015","volume":"32","author":"T Li","year":"2024","unstructured":"Li T, Ding N, Guo H, Hua R, Lin Z, Tian H et al (2024) A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage. Cell Host Microbe 32(2):191-208.e9","journal-title":"Cell Host Microbe"},{"issue":"1","key":"5376_CR240","doi-asserted-by":"publisher","first-page":"5370","DOI":"10.1038\/s41467-022-33050-0","volume":"13","author":"KF Dekkers","year":"2022","unstructured":"Dekkers KF, Sayols-Baixeras S, Baldanzi G, Nowak C, Hammar U, Nguyen D et al (2022) An online atlas of human plasma metabolite signatures of gut microbiome composition. Nat Commun. 13(1):5370","journal-title":"Nat Commun."},{"issue":"5","key":"5376_CR241","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3748\/wjg.v17.i5.557","volume":"17","author":"F Fava","year":"2011","unstructured":"Fava F, Danese S (2011) Intestinal microbiota in inflammatory bowel disease: friend of foe? World J Gastroenterol 17(5):557\u2013566","journal-title":"World J Gastroenterol"},{"issue":"7461","key":"5376_CR242","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/nature12331","volume":"500","author":"K Atarashi","year":"2013","unstructured":"Atarashi K, Tanoue T, Oshima K, Suda W, Nagano Y, Nishikawa H et al (2013) Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 500(7461):232\u2013236","journal-title":"Nature"},{"issue":"5","key":"5376_CR243","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/nri2515","volume":"9","author":"JL Round","year":"2009","unstructured":"Round JL, Mazmanian SK (2009) The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9(5):313\u2013323","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"5376_CR244","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1053\/j.gastro.2013.04.056","volume":"145","author":"MH Kim","year":"2013","unstructured":"Kim MH, Kang SG, Park JH, Yanagisawa M, Kim CH (2013) Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice. Gastroenterology. 145(2):396\u2013406","journal-title":"Gastroenterology."},{"issue":"2","key":"5376_CR245","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s10735-007-9145-y","volume":"39","author":"SI Karaki","year":"2008","unstructured":"Karaki SI, Tazoe H, Hayashi H, Kashiwabara H, Tooyama K, Suzuki Y et al (2008) Expression of the short-chain fatty acid receptor, GPR43, in the human colon. J Mol Histol 39(2):135\u2013142","journal-title":"J Mol Histol"},{"issue":"3","key":"5376_CR246","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00441-005-0140-x","volume":"324","author":"S Karaki","year":"2006","unstructured":"Karaki S, Mitsui R, Hayashi H, Kato I, Sugiya H, Iwanaga T et al (2006) Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res 324(3):353\u2013360","journal-title":"Cell Tissue Res"},{"key":"5376_CR247","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01434","volume":"9","author":"G Yang","year":"2018","unstructured":"Yang G, Chen S, Deng B, Tan C, Deng J, Zhu G et al (2018) Implication of G protein-coupled receptor 43 in intestinal inflammation: a mini-review. Front Immunol 9:1434","journal-title":"Front Immunol"},{"issue":"36","key":"5376_CR248","doi-asserted-by":"publisher","first-page":"27601","DOI":"10.1074\/jbc.M110.102947","volume":"285","author":"N Singh","year":"2010","unstructured":"Singh N, Thangaraju M, Prasad PD, Martin PM, Lambert NA, Boettger T et al (2010) Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases. J Biol Chem. 285(36):27601\u20138","journal-title":"J Biol Chem."},{"issue":"2","key":"5376_CR249","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1182\/blood-2003-09-3237","volume":"105","author":"A Halupa","year":"2005","unstructured":"Halupa A, Bailey ML, Huang K, Iscove NN, Levy DE, Barber DL (2005) A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alters their distribution. Blood 105(2):552\u2013561","journal-title":"Blood"},{"issue":"6","key":"5376_CR250","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1182\/bloodadvances.2021006816","volume":"6","author":"H Yan","year":"2022","unstructured":"Yan H, Walker FC, Ali A, Han H, Tan L, Veillon L et al (2022) The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling. Blood Adv 6(6):1754\u20131765","journal-title":"Blood Adv"},{"issue":"6","key":"5376_CR251","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1182\/blood-2016-03-708594","volume":"129","author":"KS Josefsdottir","year":"2017","unstructured":"Josefsdottir KS, Baldridge MT, Kadmon CS, King KY (2017) Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota. Blood 129(6):729\u2013739","journal-title":"Blood"},{"key":"5376_CR252","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.985141","volume":"9","author":"Y Daou","year":"2022","unstructured":"Daou Y, Falabr\u00e8gue M, Pourzand C, Peyssonnaux C, Edeas M (2022) Host and microbiota derived extracellular vesicles: Crucial players in iron homeostasis. Front Med 9:985141","journal-title":"Front Med"},{"issue":"6","key":"5376_CR253","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/nri.2016.42","volume":"16","author":"MG Rooks","year":"2016","unstructured":"Rooks MG, Garrett WS (2016) Gut microbiota, metabolites and host immunity. Nat Rev Immunol 16(6):341\u2013352","journal-title":"Nat Rev Immunol"},{"issue":"11","key":"5376_CR254","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1038\/s41577-023-00874-w","volume":"23","author":"K Donald","year":"2023","unstructured":"Donald K, Finlay BB (2023) Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease. Nat Rev Immunol 23(11):735\u2013748","journal-title":"Nat Rev Immunol"},{"issue":"16","key":"5376_CR255","doi-asserted-by":"publisher","first-page":"4137","DOI":"10.1016\/j.cell.2021.06.019","volume":"184","author":"HC Wastyk","year":"2021","unstructured":"Wastyk HC, Fragiadakis GK, Perelman D, Dahan D, Merrill BD, Yu FB et al (2021) Gut-microbiota-targeted diets modulate human immune status. Cell 184(16):4137-4153.e14","journal-title":"Cell"},{"issue":"1","key":"5376_CR256","doi-asserted-by":"publisher","first-page":"2190305","DOI":"10.1080\/19490976.2023.2190305","volume":"15","author":"SR Ames","year":"2023","unstructured":"Ames SR, Lotoski LC, Azad MB (2023) Comparing early life nutritional sources and human milk feeding practices: personalized and dynamic nutrition supports infant gut microbiome development and immune system maturation. Gut Microbes 15(1):2190305","journal-title":"Gut Microbes"},{"key":"5376_CR257","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2022.102173","volume":"69","author":"HP Browne","year":"2022","unstructured":"Browne HP, Shao Y, Lawley TD (2022) Mother-infant transmission of human microbiota. Curr Opin Microbiol 69:102173","journal-title":"Curr Opin Microbiol"},{"issue":"8","key":"5376_CR258","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.4049\/jimmunol.1701776","volume":"200","author":"KD McCoy","year":"2018","unstructured":"McCoy KD, Thomson CA (2018) The impact of maternal microbes and microbial colonization in early life on hematopoiesis. J Immunol 200(8):2519\u20132526","journal-title":"J Immunol"},{"issue":"2","key":"5376_CR259","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.1960","volume":"11","author":"R Zefferino","year":"2021","unstructured":"Zefferino R, Di Gioia S, Conese M (2021) Molecular links between endocrine, nervous and immune system during chronic stress. Brain Behav 11(2):e01960","journal-title":"Brain Behav"},{"key":"5376_CR260","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.104621","volume":"134","author":"C Gubert","year":"2020","unstructured":"Gubert C, Kong G, Renoir T, Hannan AJ (2020) Exercise, diet and stress as modulators of gut microbiota: implications for neurodegenerative diseases. Neurobiol Dis 134:104621","journal-title":"Neurobiol Dis"},{"issue":"10","key":"5376_CR261","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.3390\/microorganisms8101587","volume":"8","author":"JY Yoo","year":"2020","unstructured":"Yoo JY, Groer M, Dutra SVO, Sarkar A, McSkimming DI (2020) Gut microbiota and immune system interactions. Microorganisms 8(10):1587","journal-title":"Microorganisms"},{"key":"5376_CR262","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.cobeha.2019.01.011","volume":"28","author":"A Madison","year":"2019","unstructured":"Madison A, Kiecolt-Glaser JK (2019) Stress, depression, diet, and the gut microbiota: human\u2013bacteria interactions at the core of psychoneuroimmunology and nutrition. Curr Opin Behav Sci 28:105\u2013110","journal-title":"Curr Opin Behav Sci"},{"issue":"1","key":"5376_CR263","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1186\/s13287-023-03461-x","volume":"14","author":"W Wen","year":"2023","unstructured":"Wen W, Chen X, Shen XY, Li HY, Zhang F, Fang FQ et al (2023) Enhancing cord blood stem cell-derived NK cell growth and differentiation through hyperosmosis. Stem Cell Res Ther 14(1):295","journal-title":"Stem Cell Res Ther"},{"key":"5376_CR264","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1720696115","author":"X Gao","year":"2018","unstructured":"Gao X, Cao Q, Cheng Y, Zhao D, Wang Z, Yang H et al (2018) Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response. Proc Natl Acad Sci USA. https:\/\/doi.org\/10.1073\/pnas.1720696115","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"5376_CR265","doi-asserted-by":"publisher","first-page":"904","DOI":"10.2174\/1570159X21666230811141557","volume":"22","author":"A Menke","year":"2024","unstructured":"Menke A (2024) The HPA axis as target for depression. Curr Neuropharmacol 22(5):904\u2013915","journal-title":"Curr Neuropharmacol"},{"issue":"1","key":"5376_CR266","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1111\/prd.12452","volume":"90","author":"J Ball","year":"2000","unstructured":"Ball J, Darby I (2000) Mental health and periodontal and peri-implant diseases. Periodontol 2000 90(1):106\u201324","journal-title":"Periodontol 2000"},{"issue":"12","key":"5376_CR267","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1016\/j.jsams.2020.06.002","volume":"23","author":"CJ Bennett","year":"2020","unstructured":"Bennett CJ, Henry R, Snipe RMJ, Costa RJS (2020) Is the gut microbiota bacterial abundance and composition associated with intestinal epithelial injury, systemic inflammatory profile, and gastrointestinal symptoms in response to exertional-heat stress? J Sci Med Sport 23(12):1141\u20131153","journal-title":"J Sci Med Sport"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-025-05376-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-025-05376-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-025-05376-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T10:02:55Z","timestamp":1762509775000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-025-05376-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,27]]},"references-count":267,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["5376"],"URL":"https:\/\/doi.org\/10.1007\/s11010-025-05376-y","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"value":"0300-8177","type":"print"},{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,27]]},"assertion":[{"value":"14 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}