{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T09:53:17Z","timestamp":1781776397083,"version":"3.54.5"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"DOI":"10.1007\/s11010-026-05538-6","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:40:54Z","timestamp":1777372854000},"page":"2339-2356","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Molecular and immune profiling of colorectal polyps using FTIR microspectroscopy"],"prefix":"10.1007","volume":"481","author":[{"given":"Gustavo Jesus","family":"Vazquez-Zapien","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Martinez-Cuazitl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Garibay-Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eira","family":"Cerda-Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlos Mauricio","family":"Lopez-Barrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Salvador","family":"Garcia-Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Guerrero-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica Maribel","family":"Mata-Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"issue":"4","key":"5538_CR1","doi-asserted-by":"publisher","first-page":"226","DOI":"10.24875\/j.gamo.24000028","volume":"23","author":"DI \u00c1lvarez-L\u00f3pez","year":"2024","unstructured":"\u00c1lvarez-L\u00f3pez DI, Hern\u00e1ndez-Guerrero A, Freyria-Sutcliffe F, Hern\u00e1ndez-Aguilar JM, Reynoso-Nover\u00f3n N (2024) Current status of colorectal cancer screening in Mexico: a literature review. Gac Mex Oncol 23(4):226\u2013233. https:\/\/doi.org\/10.24875\/j.gamo.24000028","journal-title":"Gac Mex Oncol"},{"issue":"8","key":"5538_CR2","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.3390\/cancers16081530","volume":"16","author":"G Roshandel","year":"2024","unstructured":"Roshandel G, Ghasemi-Kebria F, Malekzadeh R (2024) Colorectal Cancer: Epidemiology, Risk Factors, and Prevention. Cancers (Basel) 16(8):1530. https:\/\/doi.org\/10.3390\/cancers16081530","journal-title":"Cancers (Basel)"},{"key":"5538_CR3","doi-asserted-by":"publisher","first-page":"148","DOI":"10.34141\/LJCS6421962","volume":"6","author":"H L\u00f3pez Basave","year":"2024","unstructured":"L\u00f3pez Basave H, Castillo Vega AO, Pastor Sifuentes F, Zilli Hern\u00e1ndez S, Vela Sarmiento I, Aiello Crocifoglio V et al (2024) Oncogu\u00eda de c\u00e1ncer de colon 2023. Lat Am J Clin Sci Med Technol 6:148\u2013166. https:\/\/doi.org\/10.34141\/LJCS6421962","journal-title":"Lat Am J Clin Sci Med Technol"},{"issue":"12","key":"5538_CR4","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1038\/s41575-019-0189-8","volume":"16","author":"N Keum","year":"2019","unstructured":"Keum N, Giovannucci E (2019) Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nat Rev Gastroenterol Hepatol 16(12):713\u2013732. https:\/\/doi.org\/10.1038\/s41575-019-0189-8","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"8","key":"5538_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s12032-025-02861-8","volume":"42","author":"AE Kotula","year":"2025","unstructured":"Kotula AE, Korde YV, Oyler HJ, Wakefield MR, Fang Y (2025) Colorectal polyps: pathophysiology, malignant potential, and advancements in therapeutic strategies. Med Oncol 42(8):287. https:\/\/doi.org\/10.1007\/s12032-025-02861-8","journal-title":"Med Oncol"},{"issue":"3","key":"5538_CR6","doi-asserted-by":"publisher","first-page":"224","DOI":"10.4274\/tjcd.galenos.2020.2020-12-5","volume":"31","author":"A Bulur","year":"2021","unstructured":"Bulur A, \u00c7ak\u0131r AS (2021) An Evaluation of Colorectal Polyps by Size and Advanced Histological Features: In a Secondary Referral Centre. Turk J Colorectal Dis 31(3):224\u2013229. https:\/\/doi.org\/10.4274\/tjcd.galenos.2020.2020-12-5","journal-title":"Turk J Colorectal Dis"},{"issue":"43","key":"5538_CR7","doi-asserted-by":"publisher","first-page":"16178","DOI":"10.3748\/wjg.v20.i43.16178","volume":"20","author":"CB Aarons","year":"2014","unstructured":"Aarons CB, Shanmugan S, Bleier JI (2014) Management of malignant colon polyps: current status and controversies. World J Gastroenterol 20(43):16178\u201316183. https:\/\/doi.org\/10.3748\/wjg.v20.i43.16178","journal-title":"World J Gastroenterol"},{"issue":"7","key":"5538_CR8","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.3390\/cancers14071732","volume":"14","author":"MS Hossain","year":"2022","unstructured":"Hossain MS, Karuniawati H, Jairoun AA, Urbi Z, Ooi J, John A, Lim YC, Kibria KMK, Mohiuddin AKM, Ming LC, Goh KW, Hadi MA (2022) Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies. Cancers (Basel) 14(7):1732. https:\/\/doi.org\/10.3390\/cancers14071732","journal-title":"Cancers (Basel)"},{"issue":"2","key":"5538_CR9","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.giec.2021.12.007","volume":"32","author":"Q Miller","year":"2022","unstructured":"Miller Q, Saeed O, Mesa H (2022) Clinical, Pathologic, and Molecular-Genetic Aspects of Colorectal Polyps. Gastrointest Endosc Clin N Am 32(2):313\u2013328. https:\/\/doi.org\/10.1016\/j.giec.2021.12.007","journal-title":"Gastrointest Endosc Clin N Am"},{"issue":"3","key":"5538_CR10","doi-asserted-by":"publisher","first-page":"651","DOI":"10.21608\/bmfj.2023.171743.1697","volume":"40","author":"MA Mohammed","year":"2023","unstructured":"Mohammed MA, Biomy H, Emara N, Eldamen M, Amin A (2023) Prevalence of Types and Patterns of Colorectal Polyps Detected During Colonoscopy. Benha Med J 40(3):651\u2013661. https:\/\/doi.org\/10.21608\/bmfj.2023.171743.1697","journal-title":"Benha Med J"},{"key":"5538_CR11","doi-asserted-by":"publisher","first-page":"103092","DOI":"10.1016\/j.vibspec.2020.103092","volume":"109","author":"JM Cameron","year":"2020","unstructured":"Cameron JM, Butler H, Anderson DJ, Christie L, Confield L, Spalding KE, Finlayson D, Murray S, Panni S, Rinaldi C, Sala A, Theakstone AG, Baker MJ (2020) Exploring pre-analytical factors for the optimisation of serum diagnostics: Progressing the clinical utility of ATR-FTIR spectroscopy. Vib Spectrosc 109:103092. https:\/\/doi.org\/10.1016\/j.vibspec.2020.103092","journal-title":"Vib Spectrosc"},{"issue":"12","key":"5538_CR12","doi-asserted-by":"publisher","first-page":"30223","DOI":"10.3390\/ijms161226227","volume":"16","author":"Y Chen","year":"2015","unstructured":"Chen Y, Zou C, Mastalerz M, Hu S, Gasaway C, Tao X (2015) Applications of Micro-Fourier Transform Infrared Spectroscopy (FTIR) in the Geological Sciences--A Review. Int J Mol Sci 16(12):30223\u201330250. https:\/\/doi.org\/10.3390\/ijms161226227","journal-title":"Int J Mol Sci"},{"issue":"1","key":"5538_CR13","doi-asserted-by":"publisher","first-page":"4269","DOI":"10.1038\/s41598-022-08156-6","volume":"12","author":"CCS Bandeira","year":"2022","unstructured":"Bandeira CCS, Madureira KCR, Rossi MB, Gallo JF, da Silva APMA, Torres VL, de Lima VA, J\u00fanior NK, Almeida JD, Zerbinati RM, Braz-Silva PH, Lindoso JAL, da Silva Martinho H (2022) Micro-Fourier-transform infrared reflectance spectroscopy as tool for probing IgG glycosylation in COVID-19 patients. Sci Rep 12(1):4269. https:\/\/doi.org\/10.1038\/s41598-022-08156-6","journal-title":"Sci Rep"},{"issue":"2","key":"5538_CR14","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3390\/mi13020187","volume":"13","author":"A Fadlelmoula","year":"2022","unstructured":"Fadlelmoula A, Pinho D, Carvalho VH, Catarino SO, Minas G (2022) Fourier Transform Infrared (FTIR) Spectroscopy to Analyse Human Blood over the Last 20 Years: A Review towards Lab-on-a-Chip Devices. Micromachines (Basel) 13(2):187. https:\/\/doi.org\/10.3390\/mi13020187","journal-title":"Micromachines (Basel)"},{"issue":"1","key":"5538_CR15","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1111\/brv.12237","volume":"92","author":"M Kramer","year":"2017","unstructured":"Kramer M, Font E (2017) Reducing sample size in experiments with animals: historical controls and related strategies. Biol Rev Camb Philos Soc 92(1):431\u2013445. https:\/\/doi.org\/10.1111\/brv.12237","journal-title":"Biol Rev Camb Philos Soc"},{"key":"5538_CR16","doi-asserted-by":"publisher","first-page":"1215927","DOI":"10.3389\/fmed.2023.1215927","volume":"10","author":"X Zhang","year":"2023","unstructured":"Zhang X, Hartmann P (2023) How to calculate sample size in animal and human studies. Front Med (Lausanne) 10:1215927. https:\/\/doi.org\/10.3389\/fmed.2023.1215927","journal-title":"Front Med (Lausanne)"},{"issue":"2","key":"5538_CR17","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1080\/09637486.2019.1646714","volume":"71","author":"C Ricci","year":"2020","unstructured":"Ricci C, Baumgartner J, Malan L, Smuts CM (2020) Determining sample size adequacy for animal model studies in nutrition research: limits and ethical challenges of ordinary power calculation procedures. Int J Food Sci Nutr 71(2):256\u2013264. https:\/\/doi.org\/10.1080\/09637486.2019.1646714","journal-title":"Int J Food Sci Nutr"},{"issue":"5","key":"5538_CR18","doi-asserted-by":"publisher","first-page":"101","DOI":"10.21315\/mjms2017.24.5.11","volume":"24","author":"WN Arifin","year":"2017","unstructured":"Arifin WN, Zahiruddin WM (2017) Sample Size Calculation in Animal Studies Using Resource Equation Approach. Malays J Med Sci 24(5):101\u2013105. https:\/\/doi.org\/10.21315\/mjms2017.24.5.11","journal-title":"Malays J Med Sci"},{"issue":"4","key":"5538_CR19","doi-asserted-by":"publisher","first-page":"303","DOI":"10.4103\/0976-500X.119726","volume":"4","author":"J Charan","year":"2013","unstructured":"Charan J, Kantharia ND (2013) How to calculate sample size in animal studies? J Pharmacol Pharmacother 4(4):303\u2013306. https:\/\/doi.org\/10.4103\/0976-500X.119726","journal-title":"J Pharmacol Pharmacother"},{"issue":"3","key":"5538_CR20","doi-asserted-by":"publisher","first-page":"673","DOI":"10.3390\/ani11030673","volume":"11","author":"AL Whittaker","year":"2021","unstructured":"Whittaker AL, Liu Y, Barker TH (2021) Methods Used and Application of the Mouse Grimace Scale in Biomedical Research 10 Years on: A Scoping Review. Anim (Basel) 11(3):673. https:\/\/doi.org\/10.3390\/ani11030673","journal-title":"Anim (Basel)"},{"issue":"6","key":"5538_CR21","doi-asserted-by":"publisher","first-page":"100312","DOI":"10.1016\/j.mlwa.2022.100312","volume":"8","author":"A Vidal","year":"2022","unstructured":"Vidal A, Jha S, Hassler S, Price T (2022) Face detection and grimace scale prediction of white furred mice. Mach Learn Appl 8(6):100312. https:\/\/doi.org\/10.1016\/j.mlwa.2022.100312","journal-title":"Mach Learn Appl"},{"issue":"1","key":"5538_CR22","doi-asserted-by":"publisher","first-page":"19980","DOI":"10.1038\/s41598-021-99529-w","volume":"11","author":"A Martinez-Cuazitl","year":"2021","unstructured":"Martinez-Cuazitl A, Vazquez-Zapien GJ, Sanchez-Brito M, Limon-Pacheco JH, Guerrero-Ruiz M, Garibay-Gonzalez F, Delgado-Macuil RJ, de Jesus MGG, Corona-Perezgrovas MA, Pereyra-Talamantes A, Mata-Miranda MM (2021) ATR-FTIR spectrum analysis of saliva samples from COVID-19 positive patients. Sci Rep 11(1):19980. https:\/\/doi.org\/10.1038\/s41598-021-99529-w","journal-title":"Sci Rep"},{"issue":"23","key":"5538_CR23","doi-asserted-by":"publisher","first-page":"3884","DOI":"10.3390\/cells11233884","volume":"11","author":"GJ Vazquez-Zapien","year":"2022","unstructured":"Vazquez-Zapien GJ, Martinez-Cuazitl A, Sanchez-Brito M, Delgado-Macuil RJ, Atriano-Colorado C, Garibay-Gonzalez F, Sanchez-Monroy V, Lopez-Reyes A, Mata-Miranda MM (2022) Comparison of the Immune Response in Vaccinated People Positive and Negative to SARS-CoV-2 Employing FTIR Spectroscopy. Cells 11(23):3884. https:\/\/doi.org\/10.3390\/cells11233884","journal-title":"Cells"},{"issue":"1","key":"5538_CR24","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1515\/CCLM.2009.007","volume":"47","author":"L Benezzeddine-Boussaidi","year":"2009","unstructured":"Benezzeddine-Boussaidi L, Cazorla G, Melin AM (2009) Validation for quantification of immunoglobulins by Fourier transform infrared spectrometry. Clin Chem Lab Med 47(1):83\u201390. https:\/\/doi.org\/10.1515\/CCLM.2009.007","journal-title":"Clin Chem Lab Med"},{"key":"5538_CR25","doi-asserted-by":"publisher","first-page":"3423183","DOI":"10.1155\/2023\/3423183","volume":"2023","author":"A Martinez-Cuazitl","year":"2023","unstructured":"Martinez-Cuazitl A, Mata-Miranda MM, Sanchez-Brito M, Valencia-Trujillo D, Avila-Trejo AM, Delgado-Macuil RJ, Atriano-Colorado C, Garibay-Gonzalez F, Sanchez-Monroy V, Vazquez-Zapien GJ (2023) Clinical, Biochemical, and ATR-FTIR Spectroscopic Parameters Associated with Death or Survival in Patients with Severe COVID-19. J Spectrosc 2023:3423183. https:\/\/doi.org\/10.1155\/2023\/3423183","journal-title":"J Spectrosc"},{"issue":"3","key":"5538_CR26","doi-asserted-by":"publisher","first-page":"458","DOI":"10.3390\/cells11030458","volume":"11","author":"RK Praja","year":"2022","unstructured":"Praja RK, Wongwattanakul M, Tippayawat P, Phoksawat W, Jumnainsong A, Sornkayasit K, Leelayuwat C (2022) Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) Spectroscopy Discriminates the Elderly with a Low and High Percentage of Pathogenic CD4+ T Cells. Cells 11(3):458. https:\/\/doi.org\/10.3390\/cells11030458","journal-title":"Cells"},{"key":"5538_CR27","doi-asserted-by":"publisher","first-page":"5420624","DOI":"10.1155\/2019\/5420624","volume":"2019","author":"MM Mata-Miranda","year":"2019","unstructured":"Mata-Miranda MM, Bernal-Barquero CE, Martinez-Cuazitl A, Guerrero-Robles CI, Sanchez-Monroy V, Rojas-Lopez M, Vazquez-Zapien GJ (2019) Nephroprotective Effect of Embryonic Stem Cells Reducing Lipid Peroxidation in Kidney Injury Induced by Cisplatin. Oxid Med Cell Longev 2019:5420624. https:\/\/doi.org\/10.1155\/2019\/5420624","journal-title":"Oxid Med Cell Longev"},{"issue":"7","key":"5538_CR28","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.3390\/biomedicines10071710","volume":"10","author":"C Li","year":"2022","unstructured":"Li C, Lau HC, Zhang X, Yu J (2022) Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition. Biomedicines 10(7):1710. https:\/\/doi.org\/10.3390\/biomedicines10071710","journal-title":"Biomedicines"},{"issue":"1","key":"5538_CR29","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s42826-021-00096-y","volume":"37","author":"H Arnesen","year":"2021","unstructured":"Arnesen H, M\u00fcller MHB, Aleksandersen M, \u00d8stby GC, Carlsen H, Paulsen JE, Boysen P (2021) Induction of colorectal carcinogenesis in the C57BL\/6J and A\/J mouse strains with a reduced DSS dose in the AOM\/DSS model. Lab Anim Res 37(1):19. https:\/\/doi.org\/10.1186\/s42826-021-00096-y","journal-title":"Lab Anim Res"},{"issue":"4","key":"5538_CR30","doi-asserted-by":"publisher","first-page":"939","DOI":"10.3390\/biomedicines13040939","volume":"13","author":"E Correa","year":"2025","unstructured":"Correa E, Rend\u00f3n JP, Bedoya-Betancur V, Montoya J, Duque JM, Naranjo TW (2025) Standardization of a Preclinical Colon Cancer Model in Male and Female BALB\/c Mice: Macroscopic and Microscopic Characterization from Pre-Neoplastic to Tumoral Lesions. Biomedicines 13(4):939. https:\/\/doi.org\/10.3390\/biomedicines13040939","journal-title":"Biomedicines"},{"issue":"1","key":"5538_CR31","doi-asserted-by":"publisher","first-page":"e0228413","DOI":"10.1371\/journal.pone.0228413","volume":"15","author":"LC Chartier","year":"2020","unstructured":"Chartier LC, Hebart ML, Howarth GS, Whittaker AL, Mashtoub S (2020) Affective state determination in a mouse model of colitis-associated colorectal cancer. PLoS ONE 15(1):e0228413. https:\/\/doi.org\/10.1371\/journal.pone.0228413","journal-title":"PLoS ONE"},{"key":"5538_CR32","doi-asserted-by":"publisher","first-page":"1173446","DOI":"10.3389\/fvets.2023.1173446","volume":"10","author":"PP Pepperm\u00fcller","year":"2023","unstructured":"Pepperm\u00fcller PP, Gehring J, Zentrich E, Bleich A, H\u00e4ger C, Buettner M (2023) Grimace scale assessment during Citrobacter rodentium inflammation and colitis development in laboratory mice. Front Vet Sci 10:1173446. https:\/\/doi.org\/10.3389\/fvets.2023.1173446","journal-title":"Front Vet Sci"},{"issue":"25","key":"5538_CR33","doi-asserted-by":"publisher","first-page":"eadr3467","DOI":"10.1126\/sciadv.adr3467","volume":"11","author":"B Title","year":"2025","unstructured":"Title B, Velasco E, Engelmayer N, Rayi PR, Yanai R, Hart S, Katz B, Lev S, Yarom Y, Binshtok AM (2025) Opposite regulation of medullary pain-related projection neuron excitability in acute and chronic pain. Sci Adv 11(25):eadr3467. https:\/\/doi.org\/10.1126\/sciadv.adr3467","journal-title":"Sci Adv"},{"issue":"13","key":"5538_CR34","doi-asserted-by":"publisher","first-page":"6218","DOI":"10.3390\/ijms26136218","volume":"26","author":"S Hwang","year":"2025","unstructured":"Hwang S, Lee Y, Rhee KJ (2025) Modeling ETBF-Mediated Colorectal Tumorigenesis Using AOM\/DSS in Wild-Type Mice. Int J Mol Sci 26(13):6218. https:\/\/doi.org\/10.3390\/ijms26136218","journal-title":"Int J Mol Sci"},{"key":"5538_CR35","doi-asserted-by":"publisher","first-page":"9","DOI":"10.4103\/1477-3163.78279","volume":"10","author":"M De Robertis","year":"2011","unstructured":"De Robertis M, Massi E, Poeta ML, Carotti S, Morini S, Cecchetelli L, Signori E, Fazio VM (2011) The AOM\/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. J Carcinog 10:9. https:\/\/doi.org\/10.4103\/1477-3163.78279","journal-title":"J Carcinog"},{"issue":"1","key":"5538_CR36","doi-asserted-by":"publisher","first-page":"817","DOI":"10.3390\/ijms15010817","volume":"15","author":"LH Chen","year":"2014","unstructured":"Chen LH, Song JL, Qian Y, Zhao X, Suo HY, Li J (2014) Increased preventive effect on colon carcinogenesis by use of resistant starch (RS3) as the carrier for polysaccharide of Larimichthys crocea swimming bladder. Int J Mol Sci 15(1):817\u2013829. https:\/\/doi.org\/10.3390\/ijms15010817","journal-title":"Int J Mol Sci"},{"key":"5538_CR37","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/978-1-4939-3603-8_26","volume":"1422","author":"B Parang","year":"2016","unstructured":"Parang B, Barrett CW, Williams CS (2016) AOM\/DSS Model of Colitis-Associated Cancer. Methods Mol Biol 1422:297\u2013307. https:\/\/doi.org\/10.1007\/978-1-4939-3603-8_26","journal-title":"Methods Mol Biol"},{"issue":"3","key":"5538_CR38","doi-asserted-by":"publisher","first-page":"684","DOI":"10.3390\/molecules30030684","volume":"30","author":"S Pasieczna-Patkowska","year":"2025","unstructured":"Pasieczna-Patkowska S, Cichy M, Flieger J (2025) Application of Fourier Transform Infrared (FTIR) Spectroscopy in Characterization of Green Synthesized Nanoparticles. Molecules 30(3):684. https:\/\/doi.org\/10.3390\/molecules30030684","journal-title":"Molecules"},{"issue":"9","key":"5538_CR39","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1186\/s40550-025-00119-9","volume":"12","author":"GA Francis","year":"2025","unstructured":"Francis GA, Jeyakumar SS, Ray S, Supreethee S, Vashishth R (2025) Emerging roles of FTIR spectroscopy in toxic metal profiling: innovations for food safety monitoring. Food Saf Risk 12(9):2025. https:\/\/doi.org\/10.1186\/s40550-025-00119-9","journal-title":"Food Saf Risk"},{"issue":"21","key":"5538_CR40","doi-asserted-by":"publisher","first-page":"6677","DOI":"10.1039\/d5na00522a","volume":"7","author":"M Al-Amin Kawsar","year":"2025","unstructured":"Al-Amin Kawsar M, Bhuiyan Mamun MTR, Hossain S (2025) Fourier transform infrared spectroscopic technique for analysis of inorganic materials: a review. Nanoscale Adv 7(21):6677\u20136702. https:\/\/doi.org\/10.1039\/d5na00522a","journal-title":"Nanoscale Adv"},{"issue":"6","key":"5538_CR41","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.1016\/j.ajpath.2012.08.039","volume":"181","author":"MA Cohenford","year":"2012","unstructured":"Cohenford MA, Lim S, Brown C, Chaudhry MA, Sigdel S, Beckelhimer E, Rigas B (2012) FT-IR microspectroscopy of mouse colon tissues: insight into the chemistry of carcinogenesis and diagnostic potential. Am J Pathol 181(6):1961\u20131968. https:\/\/doi.org\/10.1016\/j.ajpath.2012.08.039","journal-title":"Am J Pathol"},{"issue":"4","key":"5538_CR42","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.3390\/jcm9041095","volume":"9","author":"A Mika","year":"2020","unstructured":"Mika A, Pakiet A, Czumaj A, Kaczynski Z, Liakh I, Kobiela J, Perdyan A, Adrych K, Makarewicz W, Sledzinski T (2020) Decreased Triacylglycerol Content and Elevated Contents of Cell Membrane Lipids in Colorectal Cancer Tissue: A Lipidomic Study. J Clin Med 9(4):1095. https:\/\/doi.org\/10.3390\/jcm9041095","journal-title":"J Clin Med"},{"issue":"2","key":"5538_CR43","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1117\/1.1463051","volume":"7","author":"S Argov","year":"2002","unstructured":"Argov S, Ramesh J, Salman A, Sinelnikov I, Goldstein J, Guterman H, Mordechai S (2002) Diagnostic potential of Fourier-transform infrared microspectroscopy and advanced computational methods in colon cancer patients. J Biomed Opt 7(2):248\u2013254. https:\/\/doi.org\/10.1117\/1.1463051","journal-title":"J Biomed Opt"},{"issue":"6","key":"5538_CR44","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1080\/01635581.2018.1470657","volume":"70","author":"MF McCarty","year":"2018","unstructured":"McCarty MF, DiNicolantonio JJ (2018) Minimizing Membrane Arachidonic Acid Content as a Strategy for Controlling Cancer: A Review. Nutr Cancer 70(6):840\u2013850. https:\/\/doi.org\/10.1080\/01635581.2018.1470657","journal-title":"Nutr Cancer"},{"issue":"21","key":"5538_CR45","doi-asserted-by":"publisher","first-page":"11280","DOI":"10.1073\/pnas.200367597","volume":"97","author":"Y Cao","year":"2000","unstructured":"Cao Y, Pearman AT, Zimmerman GA, McIntyre TM, Prescott SM (2000) Intracellular unesterified arachidonic acid signals apoptosis. Proc Natl Acad Sci U S A 97(21):11280\u201311285. https:\/\/doi.org\/10.1073\/pnas.200367597","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"5538_CR46","doi-asserted-by":"publisher","first-page":"370","DOI":"10.4240\/wjgs.v7.i12.370","volume":"7","author":"B Nazha","year":"2015","unstructured":"Nazha B, Moussaly E, Zaarour M, Weerasinghe C, Azab B (2015) Hypoalbuminemia in colorectal cancer prognosis: Nutritional marker or inflammatory surrogate? World J Gastrointest Surg 7(12):370\u2013377. https:\/\/doi.org\/10.4240\/wjgs.v7.i12.370","journal-title":"World J Gastrointest Surg"},{"issue":"11","key":"5538_CR47","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1093\/ckj\/sfab078","volume":"14","author":"S Adhikari","year":"2021","unstructured":"Adhikari S, Mamlouk O, Rondon-Berrios H, Workeneh BT (2021) Hypophosphatemia in cancer patients. Clin Kidney J 14(11):2304\u20132315. https:\/\/doi.org\/10.1093\/ckj\/sfab078","journal-title":"Clin Kidney J"},{"issue":"2","key":"5538_CR48","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/gastro\/gou082","volume":"3","author":"T Rai","year":"2015","unstructured":"Rai T, Wu X, Shen B (2015) Frequency and risk factors of low immunoglobulin levels in patients with inflammatory bowel disease. Gastroenterol Rep (Oxf) 3(2):115\u2013121. https:\/\/doi.org\/10.1093\/gastro\/gou082","journal-title":"Gastroenterol Rep (Oxf)"},{"issue":"9","key":"5538_CR49","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1158\/1940-6207.CAPR-20-0592","volume":"14","author":"K Wallace","year":"2021","unstructured":"Wallace K, El Nahas GJ, Bookhout C, Thaxton JE, Lewin DN, Nikolaishvili-Feinberg N, Cohen SM, Brazeal JG, Hill EG, Wu JD, Baron JA, Alekseyenko AV (2021) Immune Responses Vary in Preinvasive Colorectal Lesions by Tumor Location and Histology. Cancer Prev Res (Phila) 14(9):885\u2013892. https:\/\/doi.org\/10.1158\/1940-6207.CAPR-20-0592","journal-title":"Cancer Prev Res (Phila)"},{"issue":"2","key":"5538_CR50","doi-asserted-by":"publisher","first-page":"119","DOI":"10.33160\/yam.2017.06.008","volume":"60","author":"H Saito","year":"2017","unstructured":"Saito H, Miyatani K, Kono Y, Murakami Y, Kuroda H, Matsunaga T, Fukumoto Y, Takano S, Osaki T, Fujiwara Y (2017) Decreased Serum Concentration of Total IgG Is Related to Tumor Progression in Gastric Cancer Patients. Yonago Acta Med 60(2):119\u2013125","journal-title":"Yonago Acta Med"},{"issue":"6","key":"5538_CR51","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1007\/s00262-013-1410-1","volume":"62","author":"RV Muthuswamy","year":"2013","unstructured":"Muthuswamy RV, Sundstr\u00f6m P, B\u00f6rjesson L, Gustavsson B, Quiding-J\u00e4rbrink M (2013) Impaired migration of IgA-secreting cells to colon adenocarcinomas. Cancer Immunol Immunother 62(6):989\u2013997. https:\/\/doi.org\/10.1007\/s00262-013-1410-1","journal-title":"Cancer Immunol Immunother"},{"issue":"1","key":"5538_CR52","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/BF00266795","volume":"94","author":"H Ditzel","year":"1990","unstructured":"Ditzel H, Erb K, Teisner B, Nielsen B, Borup-Christensen P, Jensenius JC (1990) Immunohistochemical analysis of the binding of human IgM to secretory component present in normal adult colon epithelia, but not in colon cancer and fetal colon epithelia. Histochemistry 94(1):95\u201399. https:\/\/doi.org\/10.1007\/BF00266795","journal-title":"Histochemistry"},{"issue":"2","key":"5538_CR53","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.ajg.2023.12.013","volume":"25","author":"J Zheng","year":"2024","unstructured":"Zheng J, Jin H, Tu Y (2024) Differences in circulating lymphocyte subpopulations among patients with inflammatory polyps, colorectal adenomas and colorectal cancer. Arab J Gastroenterol 25(2):129\u2013134. https:\/\/doi.org\/10.1016\/j.ajg.2023.12.013","journal-title":"Arab J Gastroenterol"},{"issue":"14","key":"5538_CR54","doi-asserted-by":"publisher","first-page":"11673","DOI":"10.3390\/ijms241411673","volume":"24","author":"Z Zheng","year":"2023","unstructured":"Zheng Z, Wieder T, Mauerer B, Sch\u00e4fer L, Kesselring R, Braum\u00fcller H (2023) T Cells in Colorectal Cancer: Unravelling the Function of Different T Cell Subsets in the Tumor Microenvironment. Int J Mol Sci 24(14):11673. https:\/\/doi.org\/10.3390\/ijms241411673","journal-title":"Int J Mol Sci"},{"issue":"11","key":"5538_CR55","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.4251\/wjgo.v14.i11.2208","volume":"14","author":"D Tsounis","year":"2022","unstructured":"Tsounis D, Villiotou V, Melpidou A, Pantsiou C, Argyrou A, Giannopoulou C, Grigoratou A, Rontogianni D, Mantzaris GJ, Papatheodoridis G (2022) Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development. World J Gastrointest Oncol 14(11):2208\u20132223. https:\/\/doi.org\/10.4251\/wjgo.v14.i11.2208","journal-title":"World J Gastrointest Oncol"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-026-05538-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11010-026-05538-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-026-05538-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T09:03:48Z","timestamp":1781773428000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11010-026-05538-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":55,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["5538"],"URL":"https:\/\/doi.org\/10.1007\/s11010-026-05538-6","relation":{},"ISSN":["1573-4919"],"issn-type":[{"value":"1573-4919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"23 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The Ethics Committee (No. CEINV-045\/22) and the Institutional Committee for the Care and Use of Laboratory Animals (No. CICUAL-018\/22) approved the research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}